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Acta Metallurgica Sinica(English Letters) 2005年第2期18卷 96-106页

作者： y.t.chen x.chen q.f.ding j.zeng technologyCenter WuhanIronandSteel（group）CooperationWuhan430080China

the microstructure and the characteristics of the inclusions embedded in ferrite matrix in simulated coarse-grain heat affected zone (CGHAZ) of a ti-Zr-treated high strength low alloy (HSLA) steel have been investigated. the microstructure of the simulated CGHAZ dominantly consisted of intragranular acicular ferrite (IAf) combining with a small amount of polygonal ferrite (Pf), widmanst tten ferrite (Wf), bainite ferrite (Bf), pearlite and martensite-austenite (M-A) islands. the Pf, Wf and Bf were generally observed at the prior austenite grain boundaries and the interlocking acicular ferrite was usually found intragranularly. It was found that the inclusions were composed of ti2O3, ZrO2, Al2O3 locating at the center of the particles and MnS lying on the surface layer of the inclusions. the intragranular complex inclusions promoted the acicular ferrite formation and the refinement of microstructure whilst those at prior austenite grain boundaries caused Pf formation on the inclusions. the simulated CGHAZ consisting of such complicated microstructure exhibited desired mechanical properties.

关键词： microalloyed HSLA steel heat affected zone microstructure mechanical property inclusion acicular ferrite titanium zirconium

the 2022 Extreme Heatwave in Shanghai,Lower Reaches of the yangtze River Valley:Combined Influences of Multiscale Variabilities

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Advances in Atmospheric Sciences 2024年第4期41卷 593-607页

作者： Ping LIANG Zhiqi ZHANG yihui ding zeng-Zhen HU qi chen Key Laboratory of Cities’Mitigation and Adaptation to Climate Change in Shanghai Shanghai Regional Climate CenterChina Meteorological AdministrationShanghai 200030China National Climate Center China Meteorological AdministrationBeijing 100081China Climate Prediction Center NCEP/NWS/NOAACollege ParkMD 20740USA

In the summer of 2022,China(especially the yangtze River Valley,yRV)suffered its strongest heatwave(HW)event since *** this study,we examined the influences of multiscale variabilities on the 2022 extreme HW in the lower reaches of the yRV,focusing on the city of *** found that about 1/3 of the 2022 HW days in Shanghai can be attributed to the long-term warming trend of global *** mid-summer of 2022,an enhanced western Pacific subtropical high(WPSH)and anomalous double blockings over the Ural Mountains and Sea of Okhotsk,respectively,were associated with the persistently anomalous high pressure over the yRV,leading to the extreme *** Pacific Decadal Oscillation played a major role in the anomalous blocking pattern associated with the HW at the decadal time ***,the positive phase of the Atlantic Multidecadal Oscillation may have contributed to regulating the formation of the double-blocking *** warming of both the warm pool of the western Pacific and tropical North Atlantic at the interannual time scale may also have favored the persistency of the double blocking and the anomalously strong *** the subseasonal time scale,the anomalously frequent phases 2-5 of the canonical northward propagating variability of boreal summer intraseasonal oscillation associated with the anomalous propagation of a weak Madden-julian Oscillation suppressed the convection over the yRV and also contributed to the ***,the 2022 extreme HW originated from multiscale forcing including both the climate warming trend and air-sea interaction at multiple time scales.

关键词： extreme heatwave multiscale variability air-sea interaction warming trend yangtze River Valley Shanghai

Rescattering of stimulated Raman side scattering in nonuniform plasmas

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Matter and Radiation at Extremes 2024年第5期9卷 68-76页

作者： S.tan q.Wang y.chen W.B.yao C.Z.xiao j.f.Myatt School of Physics and Electronics Hunan UniversityChangsha 410082China Institute of Applied Physics and Computational Mathematics Beijing 100094China School of Electrical and Information Engineering Anhui University of Science and TechnologyHuainanAnhui 232001China Department of Electrical and Computer Engineering University of Alberta9211116 St.NWEdmontonAlberta T6G 1H9Canada

Rescattering of stimulated Raman side scattering(SRSS)is observed for the first time via two-dimensional(2D)particle-in-cell(PIC)*** construct a theoretical model for the rescattering process,which can predict the region of occurrence of mth-order SRSS and estimate its *** rescattering process is identified by the 2D PIC simulations under typical conditions of a direct-drive inertial confinement fusion *** electrons produced by second-order SRSS propagate nearly perpendicular to the density gradient and gain nearly the same energy as in first-order SRSS,but there is no cascade acceleration to produce superhot *** studies for a wide range of ignition conditions show that SRSS and associated rescatterings are robust and important processes in inertial confinement fusion.

关键词： nonuniform acceleration scattering

Silencing MfN2 Drives WNt/β-catenin Nucleation to Reduce Sorafenib Sensitivity in Hepatocellular Carcinoma Cells

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Current Medical Science 2024年第4期44卷 789-798页

作者： Chai-ming zeng Bin SHAO yan-ping chen Gui-sheng ding Department of Geriatric Medicine Shengli Clinical Medical College of Fujian Medical UniversityFujian Key Laboratory of Geriatrics DiseasesFujian Provincial Center for GeriatricsFujian Provincial HospitalFuzhou350001China Department of Rehabilitation Shengli Clinical Medical College of Fujian Medical UniversityFujian Provincial HospitalFuzhou350001China Department of Gynecology Shengli Clinical Medical College of Fujian Medical UniversityFujian Provincial HospitalFuzhou350001China Department of Ultrasonography Shengli Clinical Medical College of Fujian Medical UniversityFujian Provincial HospitalFuzhou350001China

Objective Mitofusin-2(MfN2)is a mitochondrial membrane protein that plays a critical role in regulating mitochondrial fusion and cellular *** further elucidate the impact of MfN2,this study aimed to investigate its significance on hepatocellular carcinoma(HCC)cell function and its potential role in mediating *** this study investigated the effects of silencing and overexpressing MfN2 on the survival,proliferation,invasion and migration abilities,and sorafenib resistance of MHCC97-L HCC *** experiments were conducted using xAV939(aβ-catenin inhibitor)and HLy78(aβ-catenin activator)to further validate these *** Silencing MfN2 significantly promoted the survival and proliferation of MHCC97-L cells,enhanced their invasion and migration capacities,increased the IC50 of sorafenib,reduced the percentage of tUNEL-positive cells,and decreased the expression of proapoptotic ***,silencing MfN2 markedly induced the nuclear translocation ofβ-catenin,increasedβ-catenin acetylation levels and enhanced the expression of the downstream regulatory proteins Snail1 and Vimentin while inhibiting E-cadherin ***,overexpressing MfN2 reversed the effects observed in MHCC97-L cells mentioned *** results confirmed that silencing MfN2 activated theβ-catenin/epithelial-mesenchymal transition(EMt)pathway and reduced the sensitivity of cells to sorafenib,which could be reversed by xAV939 ***,overexpression of MfN2 inhibited theβ-catenin/EMt pathway and increased the sensitivity of cells to sorafenib,which could be altered by *** Low expression of MfN2 in HCC cells promotes the nuclear translocation ofβ-catenin,thereby activating the EMt pathway and mediating resistance to sorafenib.

关键词： mitofusin-2 epithelial-mesenchymal transition sorafenib resistance apoptosis hepatocellular carcinoma

Generation of polarized electron beams through self-injection in the interaction of a laser with a pre-polarized plasma

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High Power Laser Science and Engineering 2024年第3期12卷 62-68页

作者： L.R.yin x.f.Li y.j.Gu N.Cao q.Kong M.Büscher S.M.Weng M.chen Z.M.Sheng Key Laboratory of Nuclear Physics and Ion-beam Application(MoE) Institute of Modern PhysicsDepartment of Nuclear Science and TechnologyFudan UniversityShanghaiChina State Key Laboratory of High field Laser Physics Shanghai Institute of Optics and Fine MechanicsChinese Academy of SciencesShanghaiChina SANKEN(Institute of Scientific and Industrial Research) Osaka UniversityOsakaJapan Sichuan Research Institute Shanghai Jiao Tong UniversityChengduChina Peter Grünberg Institut(PGI-6) Forschungszentrum JülichJülichGermany Institut für Laser-und Plasmaphysik Heinrich-Heine-Universität DüsseldorfDüsseldorfGermany Key Laboratory for Laser Plasmas(MoE) School of Physics and AstronomyShanghai Jiao Tong UniversityShanghaiChina Collaborative Innovation Center of IfSA Shanghai Jiao Tong UniversityShanghaiChina tsung-Dao Lee Institute Shanghai Jiao Tong UniversityShanghaiChina

Polarized electron beam production via laser wakefield acceleration in pre-polarized plasma is investigated by particlein-cell *** evolution of the electron beam polarization is studied based on the thomas±Bargmann±Michel±telegdi equation for the transverse and longitudinal self-injection,and the depolarization process is found to be influenced by the injection *** the case of transverse self-injection,as found typically in the bubble regime,the spin precession of the accelerated electrons is mainly influenced by the ***,in the case of longitudinal injection in the quasi-1D regime(for example,*** et al.,***.110,135002(2013)),the direction of electron spin oscillates in the laser *** the electrons move around the laser axis,the net influence of the laser field is nearly zero and the contribution of the wakefield can be ***,an ultra-short electron beam with polarization of 99%can be obtained using longitudinal self-injection.

关键词： laser wakefield acceleration longitudinal self-injection particle-in-cell simulation polarized electron beam

StCf conceptual design report (Volume 1): Physics & detector

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frontiers of physics 2024年第1期19卷 1-154页

作者： M.Achasov x.C.Ai L.P.An R.Aliberti q.An x.Z.Bai y.Bai O.Bakina A.Barnyakov V.Blinov V.Bobrovnikov D.Bodrov A.Bogomyagkov A.Bondar I.Boyko Z.H.Bu f.M.Cai H.Cai j.j.Cao q.H.Cao x.Cao Z.Cao q.Chang K.t.Chao D.y.chen H.chen H.x.chen j.f.chen K.chen L.L.chen P.chen S.L.chen S.M.chen S.chen S.P.chen W.chen x.chen x.f.chen x.R.chen y.chen y.q.chen H.y.cheng j.cheng S.cheng t.G.cheng j.P.Dai L.y.Dai x.C.Dai D.Dedovich A.Denig I.Denisenko j.M.Dias D.Z.ding L.y.Dong W.H.Dong V.Druzhinin D.S.Du y.j.Du Z.G.Du L.M.Duan D.Epifanov y.L.fan S.S.fang Z.j.fang G.fedotovich C.q.feng x.feng y.t.feng j.L.fu j.Gao y.N.Gao P.S.Ge C.q.Geng L.S.Geng A.Gilman L.Gong t.Gong B.Gou W.Gradl j.L.Gu A.Guevara L.C.Gui A.q.Guo f.K.Guo j.C.Guo j.Guo y.P.Guo Z.H.Guo A.Guskov K.L.Han L.Han M.Han x.q.Hao j.B.He S.q.He x.G.He y.L.He Z.B.He Z.x.Heng B.L.Hou t.j.Hou y.R.Hou C.y.Hu H.M.Hu K.Hu R.j.Hu W.H.Hu x.H.Hu y.C.Hu j.Hua G.S.Huang j.S.Huang M.Huang q.y.Huang W.q.Huang x.t.Huang x.j.Huang y.B.Huang y.S.Huang N.Hüsken V.Ivanov q.P.ji j.j.jia S.jia Z.K.jia H.B.jiang j.jiang S.Z.jiang j.B.jiao Z.jiao H.j.jing x.L.Kang x.S.Kang B.C.Ke M.Kenzie A.Khoukaz I.Koop E.Kravchenko A.Kuzmin y.Lei E.Levichev C.H.Li C.Li D.y.Li f.Li G.Li G.Li H.B.Li H.Li H.N.Li H.j.Li H.L.Li j.M.Li j.Li L.Li L.Li L.y.Li N.Li P.R.Li R.H.Li S.Li t.Li W.j.Li x.Li x.H.Li x.q.Li x.H.Li y.Li y.y.Li Z.j.Li H.Liang j.H.Liang y.t.Liang G.R.Liao L.Z.Liao y.Liao C.x.Lin D.x.Lin x.S.Lin B.j.Liu C.W.Liu D.Liu f.Liu G.M.Liu H.B.Liu j.Liu j.j.Liu j.B.Liu K.Liu K.y.Liu K.Liu L.Liu q.Liu S.B.Liu t.Liu x.Liu y.W.Liu y.Liu y.L.Liu Z.q.Liu Z.y.Liu Z.W.Liu I.Logashenko y.Long C.G.Lu j.x.Lu N.Lu q.f.Lü y.Lu y.Lu Z.Lu P.Lukin f.j.Luo t.Luo x.f.Luo y.H.Luo H.j.Lyu x.R.Lyu j.P.Ma P.Ma y.Ma y.M.Ma f.Maas S.Malde D.Matvienko Z.x.Meng R.Mitchell A.Nefediev y.Nefedov S.L.Olsen q.Ouyang P.Pakhlov G.Pakhlova x.Pan y.Pan E.Passemar y.P.Pei H.P.Peng L.Peng x.y.Peng x.j.Peng K.Peters S.Pivovarov E.Pyata B.B.qi y.q.qi W.B.qian y.qian C.f.qiao j.j.qin j.j.qin L.q.qin x.S.qin t.L.qiu j.Rademacker C.f.Redmer H.y.Sang Anhui University Hefei 230039China Beihang University Beijing 100191China Budker Institute of Nuclear Physics Novosibirsk 630090Russia CAS Key Laboratory of theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China Cavendish Laboratory University of CambridgeJJ Thomson AveCambridge CB30HEUnited Kingdom Central China Normal University Wuhan 430079China Central South University Changsha 410083China China University of Geosciences Wuhan 430074China China University of Mining and technology Xuzhou 221116China École Polytechnique fédérale de Lausanne(EPfL) LausanneSwitzerland fudan University Shanghai 200433China Goethe University frankfurt D-60325 Frankfurt am MainGermany Guangxi Normal University Guilin 541004China Guangxi Uninversity Nanning 530004China Hangzhou Institute for Advanced Study UCASHangzhou 310024China Hebei Normal University Shijiazhuang 050024China Hebei University Baoding 071002China Hefei University of technology Hefei 230601China Helmholtz Institute Mainz Staudinger Weg 18D-55099 MainzGermany Henan Normal University Xinxiang 453007China Henan University Kaifeng 475004China High Energy Physics Center Chung-Ang UniversitySeoul 06974Korea Higher School of Economy 11 Pokrovsky Bulvar Moscow 109028Russia Huangshan University Huangshan 245000China Hubei University of Automotive technology Shiyan 442002China Hunan Normal University Changsha 410081China Hunan University of Science and technology Xiangtan 411201China Hunan University Changsha 410082China Indiana University BloomingtonIndiana 47405USA Inner Mongolia University Hohhot 010021China Institute of Advanced Science facilities Shenzhen 518107China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China Institute of Physics Academia SinicaTaipeiTaiwan 11529China Institute of theoretical Physics Chinese Academy of SciencesBeijing 100190China jilin University Changch

the superτ-charm facility(StCf)is an electron–positron collider proposed by the Chinese particle physics *** is designed to operate in a center-of-mass energy range from 2 to 7 GeV with a peak luminosity of 0.5×10^(35) cm^(–2)·s^(–1) or *** StCf will produce a data sample about a factor of 100 larger than that of the presentτ-charm factory—the BEPCII,providing a unique platform for exploring the asymmetry of matter-antimatter(charge-parity violation),in-depth studies of the internal structure of hadrons and the nature of non-perturbative strong interactions,as well as searching for exotic hadrons and physics beyond the Standard *** StCf project in China is under development with an extensive R&D *** document presents the physics opportunities at the StCf,describes conceptual designs of the StCf detector system,and discusses future plans for detector R&D and physics case studies.

关键词： electron–positron collider tau-charm region high luminosity StCf detector conceptual design

Development of a novel Eu^(3+)-doped tantalate red-emitting phosphor for w-LEDs application

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journal of Rare Earths 2024年第8期42卷 1479-1488,I0003页

作者： fan zeng jingjing Ru Bing Zhao feiyun Guo jianzhong chen College of Chemistry and Materials Fujian Province University Key Laboratory of Green Energy and Environment CatalysisNingde Normal University.Ningde352100China School of Environment and Resources School of Carbon Neutral and Modern IndustryFujian Normal UniversityFuzhou350007China College of Information and Mechanical&Electrical Engineering Ningde Normal UniversityNingde352100China College of Chemistry Fuzhou UniversityFuzhou350108China

two novel phosphors LiBa_(4(1-x))Eu_(4x)ta_(3)O_(12)(H-LBtO:xEu^(3+)) and Li_(0.25)Ba_(1-x)Eu_(x)ta_(0.75)O_(3)(C-LBtO:xEu^(3+))were prepared successfully by a molten salt *** transformation between these two structures was realized by changing the sintering temperature or changing the Eu^(3+) ions concentration,which was also demonstrated by the x-ray diffraction(xRD),scanning electron microscopy(SEM),diffuse reflectance spectra(DRS),and photoluminescence excitation(PLE) analyses,Both the sintering temperature and the Eu^(3+)ions doping concentration have significant impact on the formation of the crystal *** these phosphors sintered at 1023 K exhibit two major luminescence lines at 594 and 614 nm under nearUV light of 395 nm excitation,corresponding to Eu^(3+)ions typical transitions of ^(5)D_(0)→^(7)f_(1) and ^(5)D_(0)→^(7)f_(2).the optimum concentration of Eu^(3+) ions is 9 mol% for C-LBtO:xEu^(3+) samples and the quenching interaction type is the nearest-neighbor ion *** thermal stability of the C-LBtO:0.09Eu^(3+)sample was investigated in detail and the device application further suggests that C-LBtO:0.09Eu^(3+) can be used as a red phosphor for near-UV excited w-LEDs in lighting.

关键词： Phosphor tantalate LED device Rare earths

A Catalog of ^(13)CO Clumps from the MWISP in l=10°–20°

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Research in Astronomy and Astrophysics 2024年第5期24卷 218-234页

作者： xiaoyu Luo Sheng Zheng Zhibo jiang Zhiwei chen yao Huang Shuguang zeng xiangyun zeng Rui Zhang chen Long Guangrong Zhou jinbo Hu Center for Astronomy and Space Sciences China Three Gorges UniversityYichang 443000China College of Electrical Engineering and New Energy China Three Gorges UniversityYichang 443000China College of Science China Three Gorges UniversityYichang 443000China Purple Mountain Observatory Chinese Academy of SciencesNanjing 210023China

In this study, we present a catalog of molecular clumps extracted from ^(13)CO(j=1-0) emission data of the Milky Way Imaging Scroll Painting(MWISP) project. the data covers the inner Milky Way within the longitude range10°≤l≤20° and the latitude strip of |b|≤ 5°. 25. the workflow for the extraction of clumps, namely facet-SS-3DClump, consists of two parts: the identification of clump candidates and their verification. first, facet-SS-3DClump employs facetClumps to identify clump candidates. Subsequently, high-confidence clumps are obtained by cross-matching with the clumps detected by other algorithms, such as dendrogram. Second, these high-confidence clumps are used as prior knowledge to train a semi-supervised deep clustering approach, SS-3D-Clump, which is applied to verify clump candidates detected by facetClumps, providing confidence levels for the molecular clumps. finally, the catalog comprising 18,757 molecular clumps was obtained using facet-SS-3D-Clump, and the catalog is 90% complete above 37 K km s^(-1). We observe a significant deviation of the mean Galactic latitude for clumps within |b|≤ 2° from the midplane, with b=-0°.110. We found that 82.3% of the dust clumps correspond to ^(13)CO clumps by matching with Herschel infrared dust clumps. In the future, facet-SS-3D-Clump will be applied to detect ^(13)CO clumps in the entire MWISP data.

关键词： ISM molecules methods data analysis-stars formation

towards complex scenes: A deep learning-based camouflaged people detection method for snapshot multispectral images

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Defence technology（防务技术） 2024年第4期34卷 269-281页

作者： Shu Wang Dawei zeng yixuan xu Gonghan yang feng Huang Liqiong chen School of Mechanical Engineering and Automation Fuzhou UniversityFuzhou 350108China

Camouflaged people are extremely expert in actively concealing themselves by effectively utilizing cover and the surrounding environment. Despite advancements in optical detection capabilities through imaging systems, including spectral, polarization, and infrared technologies, there is still a lack of effective real-time method for accurately detecting small-size and high-efficient camouflaged people in complex real-world scenes. Here, this study proposes a snapshot multispectral image-based camouflaged detection model, multispectral yOLO(MS-yOLO), which utilizes the SPD-Conv and Sim AM modules to effectively represent targets and suppress background interference by exploiting the spatial-spectral target information. Besides, the study constructs the first real-shot multispectral camouflaged people dataset(MSCPD), which encompasses diverse scenes, target scales, and attitudes. to minimize information redundancy, MS-yOLO selects an optimal subset of 12 bands with strong feature representation and minimal inter-band correlation as input. through experiments on the MSCPD, MS-yOLO achieves a mean Average Precision of 94.31% and real-time detection at 65 frames per second, which confirms the effectiveness and efficiency of our method in detecting camouflaged people in various typical desert and forest scenes. Our approach offers valuable support to improve the perception capabilities of unmanned aerial vehicles in detecting enemy forces and rescuing personnel in battlefield.

关键词： Camouflaged people detection Snapshot multispectral imaging Optimal band selection MS-yOLO Complex remote sensing scenes

SRy-Box transcription factor 9 triggers yAP nuclear entry via direct interaction in tumors

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Signal transduction and targeted therapy 2024年第5期9卷 2285-2297页

作者： Hui qian chen-Hong ding fang Liu Shi-jie chen chen-Kai Huang Meng-Chao xiao xia-Lu Hong Ming-chen Wang fang-Zhi yan Kai ding ya-Lu Cui Bai-Nan Zheng jin ding cheng Luo xin Zhang Wei-fen xie Department of Gastroenterology Changzheng HospitalNaval Medical UniversityShanghaiChina Department of Gastroenterology Shanghai East HospitalSchool of MedicineTongji UniversityShanghaiChina Drug Discovery and Design Center CAS Key Laboratory of Receptor ResearchState Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaChinese Academy of SciencesShanghaiChina Department of Gastroenterology First Affiliated Hospital of Nanchang UniversityNanchangChina Clinical Cancer Institute Center for Translational MedicineNaval Medical UniversityShanghaiChina

the translocation of yAP from the cytoplasm to the nucleus is critical for its activation and plays a key role in tumor ***,the precise molecular mechanisms governing the nuclear import of yAP are not fully *** this study,we have uncovered a crucial role of SOx9 in the activation of ***9 promotes the nuclear translocation of yAP by direct ***,we have identified that the binding between Asp-125 of SOx9 and Arg-124 of yAP is essential for SOx9-yAP interaction and subsequent nuclear entry of ***,we have discovered a novel asymmetrical dimethylation of yAP at Arg-124(yAP-R124me2a)catalyzed by ***-R124me2a enhances the interaction between yAP and SOx9 and is associated with poor prognosis in multiple ***,we disrupted the interaction between SOx9 and yAP using a competitive peptide,S-A1,which mimics anα-helix of SOx9 containing Asp-125.S-A1 significantly inhibits yAP nuclear translocation and effectively suppresses tumor *** study provides the first evidence of SOx9 as a pivotal regulator driving yAP nuclear translocation and presents a potential therapeutic strategy for yAP-driven human cancers by targeting SOx9-yAP interaction.

关键词： interaction interaction precise