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原子核物理评论 2016年第2期33卷 212-216页

作者： S.kubono 何建军 H.yamaguchi D.M.kahl S.Hayakawa T.Teranishi S.Cheribini M.Gulino y.k.kwon T.Hashimoto y.Wakabayashi N.Iwasa S.kato T.komatsubara D.N.Binh L.H.khiem N.N.Duy T.kawabata C.Spitaleri G.G.Rapisarda M.La Cognata L.Lamia R.G.Pizzone S.Romano A.Coc N.de Sereville F.Hammache G.kiss S.Bishop Institute of Modern Physics Chinese Academy of Sciences RIkEN Nishina Center Center for Nuclear Study University of Tokyo Department of Physics Kyushu University Laboratori Nazionali del Sud Istituto Nazionale di Fisica Nucleare Institute for Basic Science 70Yuseong-daero 1689-gil RIkEN Nishina Center 2-1 Hirosawa Department of Physics Tohoku University Department of Physics Yamagata University Institute of Physics Vietnam Academy for Science and Technology Department of Physics Kyoto University IN2P3 Institute for Nuclear Research (MTA-ATOMkI) TUM

The paper includes discussions on the important role of neutron and alpha configurations in proton-rich nuclei in nuclear astrophysics in terms of nucleosynthesis under extremely high-temperature hydrogenburning conditions. The νp-process, which is supposed to take place at the very early epoch of type II supernovae, has considerable neutrons and alphas together with protons. The alpha-induced reactions on proton-rich unstable nuclei in the light mass regions is expected to play a crucial role, but very few of them were investigated well yet because of the experimental difficulties. Specifically, I report our recent experimental effort for the breakout process from the pp-chain region,~7Be(α, γ)^(11)C(α,p)^(14)N under the νp-process. The neutron-induced reactions on proton-rich nuclei, which is even more a challenging subject, were investigated previously for very few nuclei. One possible experimental method is the Trojan Horse Method(THM). We successfully have applied THM to the ^(18)F(n,α)^(14)N reaction study with an unstable beam of ^(18)F.

关键词： alpha-and neutron-induced stellar reactions in proton-rich nuclear region νp-process pp-chain breakout nuclear cluster structures in astrophysics low-energy RI beam

Pan-TRk positive uterine sarcoma in immunohistochemistry without neurotrophic tyrosine receptor kinase gene fusions:A case report

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World Journal of Clinical Cases 2025年第2期13卷 39-49页

作者： Seungmee Lee yu-Ra Jeon Changmin Shin Sun-young kwon Sojin Shin Department of Obstetrics and Gynecology Keimyung University School of MedicineDaegu 42601South Korea Department of Pathology and Institute for Cancer Research Keimyung University School of MedicineDaegu 42601South Korea

BACkGROUND The classification of uterine sarcomas is based on distinctive morphological and immunophenotypic characteristics,increasingly supported by molecular genetic *** on neurotrophic tyrosine receptor kinase(NTRk)gene fusionpositive uterine sarcoma,potentially aggressive and morphologically similar to fibrosarcoma,are limited due to its recent ***-TRk immunohistochemistry(IHC)analysis serves as an effective screening tool with high sensitivity and specificity for NTRk-fusion *** SUMMARy We report a case of a malignant mesenchymal tumor originating from the uterine cervix,which was pan-TRk IHC-positive but lacked NTRk gene fusions,accompanied by a brief literature review.A 55-year-old woman presented to the emergency department with abdominal pain and distension,exhibiting significant ascites and multiple solid pelvic *** examination revealed a tumor encompassing the uterine cervix,extending to the vagina and uterine corpus.A punch biopsy of the cervix indicated NTRk sarcoma with positive immunochemical pan-TRk ***,subsequent next generation sequencing revealed no NTRk gene fusion,leading to a diagnosis of poorly differentiated,advanced-stage *** The clinical significance of NTRk gene fusion lies in potential treatment with TRk inhibitors for positive *** such rare tumors is crucial due to the potential applicability of tropomyosin receptor kinase inhibitor treatment.

关键词： Uterine sarcoma Cervical sarcoma Neurotrophic tyrosine receptor kinase gene fusion Next generation sequencing Case report

Acoustic Emission Monitoring and Microscopic Investigation of Cracks in ERCuNi Cladding

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Journal of Materials Science & Technology 2003年第3期19卷 201-205页

作者： S.P.Lu O.y.kwon k.J.Lee T.B.kim Department of Mechanical Engineering Inha University253 Yonghyun-dongInchon 402-751KoreaDepartment of Mechanical EngineeringInha University253 Yonghyun-dongInchon 402-751KoreaDepartment of Mechanical EngineeringInha University253 Yonghyun-dongInchon 402-751KoreaDepartment of Mechanical EngineeringInha University253 Yonghyun-dongInchon 402-751Korea

A corrosion resistant CuNi cladding was deposited on SM45C (equivalent to AISI1045) substrate by DC inverse arc welding. During the welding process, a three channel acoustic emission (AE) monitoring system was applied to detect the crack signals generating from both the cladding process and after cladding. Characteristics of the welding crack signal and noise signal had been analyzed systematically. Based on the record time of the signal, the solidification crack and delayed crack were distinguished. By two-dimensional AE source location, the crack position was located, and then investigated by scanning electron microscopy (SEM). Results showed that the AE system could detect the welding crack with high sensitivity and the two-dimensional source location could accurately determine the crack position. Microstructures of the cladding and heat affected zone (HAZ) were examined. Dendrites in the cladding and coarse grains in the HAZ were found.

关键词： Cladding Acoustic emission monitoring Crack CuNi alloy

The Effect of Non-equilibrium Condensation on the Drag Coefficient in a Transonic Airfoil Flow

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Journal of Thermal Science 2012年第6期21卷 518-524页

作者： I.W.kim M.M.A.Alam S.J.Lee y.D.kwon S.B.kwon School of Mechanical Engineering Kyungpook Nat.Uni.1370Sankyuk-dongDaegu 702-701Korea Dept.of Advanced & Control Eng.Saga Uni.Japan

In this study, a transonic flow past NACA0012 profile at angle of attack α=0^0 whose aspect ratio AR is 1.0 with non-equilibrium condensation is analyzed by numerical analysis using a TVD scheme and is investigated using an intermittent indraft type supersonic wind tunnel. Transonic flows of 0.78-0.90 in free stream Mach number with the variations of the stagnation relative humidity（φ0） are tested. For the same free stream Mach number, the increase in φ0 causes decrease in the drag coefficient of profile which is composed of the drag components of form, viscous and wave. In the case of the same Moo and To, for more than φ0=30%, despite the irreversibility of process in non-equilibrium condensation, the drag by shock wave decreases considerably with the increase of φ0. On the other hand, it shows that the effect of condensation on the drag coefficients of form and viscous is negligible. As an example, the decreasing rate in the drag coefficient of profile caused by the influence of non-equilibrium condensation for the case of M∞=0.9 and φ0 =50% amounts to 34%. Also, it were turned out that the size of supersonic bubble （that is, the maximum height of supersonic zone） and the deviation of pressure coefficient from the value for M=1 decrease with the increase of φ0 for the same M∞.

关键词： Non-equilibrium condensation Transonic Moist air Drag coefficient Pressure coefficient

Low cycle fatigue properties and cyclic deformation behavior of as-extruded AZ31 magnesium alloy

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Transactions of Nonferrous Metals Society of China 2010年第B07期20卷 533-539页

作者： S.kwon k.SONG k.S.SHIN S.I.kWUN Department of Materials Science and Engineering Korea University School of Materials Science and Engineering Seoul National University

The low cycle fatigue(LCF)properties of as-extruded AZ31 Mg alloy were investigated under total strain amplitudes in the range of 0.4%-1.2%with strain rate of 1×10- 2s -*** to the twinning effect in compression during loading and the detwinning effect during unloading,the alloy showed an asymmetric hysteresis *** cyclic stress response exhibited cyclic hardening at high total strain *** cyclic deformation behaviors were discussed using the Coffin-Manson plot,which divided the plastic strain amplitudes into the tension side and the compression *** the LCF tests that were started from either tension or compression under a total strain amplitude of 1.0%,the interaction between the twinning effect and dislocation was *** twinning effect during the LCF test and the variation of the dislocation density were investigated using optical microscopy and transmission electron microscopy,respectively.

关键词： AZ31 magnesium alloy low cycle fatigue twinning dislocation

Influence of Indian mustard (Brassica juncea) on rhizosphere soil solution chemistry in long-term contaminated soils:A rhizobox study

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Journal of Environmental Sciences 2010年第1期22卷 98-105页

作者： kwon-Rae kim Gary Owens Soon-lk kwon Climate Change & Agroecology Division Department of Agricultural EnvironmentNational Academy of Agricultural ScienceRDARepublic of Korea Centre for Environmental Risk Assessment and Remediation University of South Australia

This study investigated the influence of Indian mustard （Brassicajuncea） root exudation on soil solution properties （pH, dissolved organic carbon （DOC）, metal solubility） in the rhizosphere using a rhizobox. Measurement was conducted following the cultivation of Indian mustard in the rhizobox filled four different types of heavy metal contaminated soils （two alkaline soils and two acidic soils）. The growth of Indian mustard resulted in a significant increase （by 0.6 pH units） in rhizosphere soil solution pH of acidic soils and only a slight increase （〈 0.1 pH units） in alkaline soils. Furthermore, the DOC concentration increased by 17-156 mg/L in the rhizosphere regardless of soil type and the extent of contamination, demonstrating the exudation of DOC from root. Ion chromatographic determination showed a marked increase in the total dissolved organic acids （OAs） in rhizosphere. While root exudates were observed in all soils, the amount of DOC and OAs in soil solution varied considerably amongst different soils, resulting in significant changes to soil solution metals in the rhizosphere. For example, the soil solution Cd, Cu, Pb, and Zn concentrations increased in the rhizosphere of alkaline soils compared to bulk soil following plant cultivation. In contrast, the soluble concentrations of Cd, Pb, and Zn in acidic soils decreased in rhizosphere soil when compared to bulk soils. Besides the influence of pH and DOC on metal solubility, the increase of heavy metal concentration having high stability constant such as Cu and Pb resulted in a release of Cd and Zn from solid phase to liquid phase.

关键词： dissolved organic carbon heavy metals root exudates solubility rhizosphere chemistry

4-1BB signaling activates glucose and fatty acid metabolism to enhance CD8^(+) T cell proliferation

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Cellular & Molecular Immunology 2017年第9期14卷 748-757页

作者： Beom k Choi Do y Lee Don G Lee young H kim Seon-Hee kim Ho S Oh Chungyong Han Byoung S kwon Cancer Immunology Branch Division of Cancer BiologyNational Cancer CenterGoyangGyeonggi 10408Korea Department of Internal Medicine Yonsei University College of MedicineSeoul 120-752Korea Immune Cell Production Unit Program for Immunotherapeutic ResearchNational Cancer CenterGyeonggi 10408Korea Eutilex Catholic University School of MedicineSeoul 06591Korea Department of Medicine Tulane University Health Sciences CenterNew OrleansLA 70112USA

4-1BB(CD137)is a strong enhancer of the proliferation of CD8^(+)T *** these cells require increased production of energy and biomass to support their proliferation,we hypothesized that 4-1BB signaling activated glucose and fatty acid *** found that treatment with agonistic anti-4-1BB mAb promoted the proliferation of CD8^(+)T cells in vitro,increasing their size and *** with a glycolysis inhibitor and a fatty acid oxidation inhibitor revealed that CD8^(+)T cell proliferation required both glucose and fatty acid ***-4-1BB treatment increased glucose transporter 1 expression and activated the liver kinase B1(LkB1)-AMP-activated protein kinase(AMPk)-acetyl-CoA carboxylase(ACC)signaling pathway,which may be responsible for activating the metabolism of glucose and fatty *** also examined whether blocking glucose or fatty acid metabolism affected cell cycle progression and the anti-apoptotic effect of 4-1BB *** increase of anti-apoptotic factors and cyclins in response to anti-4-1BB treatment was completely prevented by treating CD8^(+)T cells with the fatty acid oxidation inhibitor,etomoxir,but not with the glycolysis inhibitor,*** conclude that anti-4-1BB treatment activates glucose and fatty acid metabolism thus supporting the increased demand for energy and biomass,and that fatty acid metabolism plays a crucial role in enhancing the cell cycle progression of anti-CD3-activated CD8^(+)T cells in vitro and the anti-apoptotic effects of 4-1BB signaling on these cells.

关键词： AMPk CD8^(+)T cells 4-1BB(CD137) LkB1 metabolism

A Study of the Influence of Air-knife Tilting on Coating Thickness in Hot-dip Galvanizing

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Journal of Thermal Science 2009年第3期18卷 262-267页

作者： Tae-Seok CHO young-Doo kwon Soon-Bum kwon School of Mechanical Engineering Kyungpook National University

Gas wiping is a decisive operation in hot-dip galvanizing process. In special, it has a crucial influence on the thickness and uniformity in coating film, but may be subsequently responsible for the problem of splashing. The progress of industry demands continuously the reduction of production costs which may relate directly with the increase of coating speed, and the speed up of coating results in the increase of stagnation pressure in gas wiping system in final. It is known that the increase of stagnation pressure may accompany a harmful problem of splashing in general. Together with these, also, from the view point of energy consumption, it is necessary to design a nozzle optimally. And there is known that the downward tilting of nozzle using in air knife system is effective to prevent in somewhat the harmful problem of splashing. In these connections, first, we design a nozzle with constant expansion rate. Next, for the case of actual coating conditions in field, the effects of tilting of the constant expansion rate nozzle are investigated by numerical analysis. Under the present numerical conditions, it was turned out that the nozzle of constant expansion rate of p = having a downward jet angle of 5^0 is the most effective to diminish the onset of splashing, while the influence of small tilting of the nozzle on impinging wall pres- sure itself is not so large.

关键词： Air-knife Constant expansion rate nozzle Impinging pressure Wall shear stress Hot-dip galvanizing Coating thickness Splashing

Experimental and Computational Studies on Coanda Nozzle Flow for the Air knife Application

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Journal of Thermal Science 2007年第2期16卷 164-169页

作者： Soon-Bum kwon Dong-Won LEE young-Doo kwon School of Mechanical Engineering Kyungpook National University1370Sankyuk-dongDaegu 702-701Korea

To control the film thickness of zinc in the process of continuous hot-dip galvanizing, it is known from the early days that the gas wiping through an air knife is the most effective one. The gas wiping using in galvanizing process brings about a problem of splashing from the strip edge for a certain high speed of coating. So, in the present study, the effects of the deflection angle of Coanda nozzle on jet structure and the distribution of impinging pres- sure at the plate surface are investigated numerically and experimentally. In numerical analysis, the governing equations consisted of three-dimensional time dependent full Navier-Stokes equations, standard k-ε turbulence model to solve turbulent stTess and so on are employed. In experiment, 16 channel pressure scanning valve and 3-axis auto traversing unit are used to measure the impinging pressure at the strip surface. As a result, it is found that the smaller the deflection angle for the same nozzle slit of air knife is, the larger the impinging pressure is. To reduce the size of separation bubble and to enhance the cutting ability, it is recommendable to use an air knife with the Coanda nozzle.

关键词： Air knife Coanda effect edge splashing gas wiping hot-dip galvanizing impinging jet