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Increasing polymer scission rate by tying an overhand knot

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Science China Chemistry 2024年

作者： yuheng Hu Jennifer T.Ou Jim y.huang yuanning Feng Department of Chemistry and Biochemistry The University of Oklahoma

Similar to the phenomenon of knotted ropes in life, knotted climbing ropes will reduce their strength due to knots. Although computer simulations [1], theoretical speculation[2,3], and intuition [3] suggest that similar processes may occur at the nanoscale, this hypothesis has not been experimentally proven before. With the increasing maturity of molecular recognition and self-assembly, a research communication by Leigh et al. [4]

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INFLUENCE OF ALLOyING ELEMENTS ON HyDROGEN DIFFUSION USING SCM-DV-X_α

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Acta Metallurgica Sinica(English Letters) 2004年第1期17卷 71-76页

作者： y.huang D.M.Xing School of Materials Science and Engineering Tianjin University Tianjin 300072 ChinaSchool of Physics Tianjin Normal UniversityTianjin 300071China

The influence of alloy composition (Ti, Mn, TiN) on hydrogen diffusion in Fe was studied in detail using SCM-DV-Xα method. The voltage barriers were obtained via calculation on Fe clusters containing the alloy elements such as Ti, Mn as well as the chemical compound TiN respectively. The results showed that Ti element produced deep trap in Fe, decreasing the diffusion coefficient of hydrogen elements, Mn element did not produce deep trap in Fe, decreasing the diffusion coefficient slightly and TiN in Fe produced very deep "trap" decreasing the diffusion coefficient obviously. The calculation results were in agreement with experiment results.

关键词： hydrogen diffusion SCM-DV-Xα method cluster

Genes important for survival or reproduction in Varroa destructor identified by RNAi

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Insect Science 2019年第1期26卷 68-75页

作者： Zachary y.huang Guowu Bian Zhiyong Xi Xianbing Xie Department of Laboratory Animal Science Nanchang UniversityNanchangJiangxiChina Department of Entomology Michigan State UniversityEast LansingMIUSA Department of Microbiology and Molecular Genetics Michigan State UniversityEast LansingMI USA Ecology Evolutionary Biology and BehaviorMichigan State UniversityEast LansingMIUSA BEACON Center for the Study of Evolution in Action Michigan State UniversityEast LansingMIUSA

The Varroa mite,(Varroa destructor),is the worst threat to honey bee health *** explore the possibility of using RNA interference to control this pest, we determined the effects of knocking down various genes on Varroa mite survival and ***-stranded RNA (dsRNA)of six candidate genes (Da,Pros26S,RpL8, RpL11,RpPO and RpS13)were synthesized and each injected into Varroa mites,then mite survival and reproduction were *** of dsRNA for Da (Daughterless)and Pros26S (Gene for proteasome 26S subunit adenosine triphosphatase)caused a significant reduction in mite survival,with 3.57%±1.94% and 30.03%±11.43% mites surviving at 72 h post-inj ection (hpi),*** mites injected with green fluorescent protein (GFP)-dsRNA showed survival rates of 81.95%±5.03% and 82.36 ±2.81%,respectively. Injections of dsRNA for four other genes (RpL8,RpL11,RpPO and RpS13)did not affect survival significantly,enabling us to assess their effect on Varroa mite *** number of female offspring per mite was significantly reduced for mites injected with dsRNA of each of these four genes compared to their GFP-dsRNA *** of the target genes was verified by real-time polymerase chain reaction for two genes important for reproduction (RpL8,RpL11)and one gene important for survival (Pros26S). In conclusion,through RNA interference,we have discovered two genes important for mite survival and four genes important for mite *** genes could be explored as possible targets for the control of Varroa destructor in the future.

关键词： Apis mellijera reproduction RNAi survival Varroa destructor

The Role of TNF Related Apoptosis-Inducing Ligand in Neurodegenerative Diseases

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Cellular & Molecular Immunology 2005年第2期2卷 113-122页

作者： y.huang N.Erdmann H.Peng y.Zhao ThelaboratoryofNeurotoxicologyattheCenterforNeurovirology＆NeurodegenerativeDisorders ／／Dept.Pharmacology Dept.ofSurgery UniversityofNebraskaMedicalCenterOmahaNE68198-5880USA／／InstituteofAnimalResearchChineseAcademyofScienceChina

A hallmark of all forms of neurodegenerative diseases is impairment of neuronal functions,and in many cases neuronal cell *** the etiology of neurodegenerative diseases may be distinct,different diseases display a similar pathogenesis,for example abnormal immunity within the central nervous system(CNS),activation of macrophage/microglia and the involvement of proinflammatory *** studies show that neurons in a neurodegenerative state undergo a highly regulated programmed cell death,also called ***-related apoptosis-inducing ligand(TRAIL),a member of the TNF family,has been shown to be involved in apoptosis during many *** one member of a death ligand family,TRAIL was originally thought to target only tumor cells and was not present in ***,recent data showed that TRAIL was unregulated in HIV-1-infected and immune-activated macrophages,a major disease inducing cell during HIV-1-assoeiated dementia(HAD).TRAIL is also induced on neuron by β-amyloid protein,an important pathogen for Alzheimer's *** this review,we summarize the possible common aspects that TRAIL involved those neurodegenerative diseases,TRAIL induced apoptosis signaling in the CNS cells,and specific role of TRAIL in individual *** & Molecular Immunology.2005;2(2):113-122.

关键词： Alzheimer's disease HⅣ-1 associated dementia multiple sclerosis apoptosis TRAIL macrophage

Leveraging generative adversarial networks to create realistic scanning transmission electron microscopy images

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npj Computational Materials 2023年第1期9卷 1492-1500页

作者： Abid Khan Chia-Hao Lee Pinshane y.huang Bryan K.Clark Department of Physics University of Illinois Urbana-ChampaignUrbanaIL 61801USA Department of Materials Science and Engineering University of Illinois Urbana-ChampaignUrbanaIL 61801USA Materials Research Laboratory University of Illinois Urbana-ChampaignUrbanaIL 61801USA Institute for Condensed Matter Theory and IQUIST and NCSA Center for Artificial Intelligence Innovation University of Illinois Urbana-ChampaignUrbanaIL 61801USA

The rise of automation and machine learning(ML)in electron microscopy has the potential to revolutionize materials research through autonomous data collection and processing.A significant challenge lies in developing ML models that rapidly generalize to large data sets under varying experimental *** address this by employing a cycle generative adversarial network(CycleGAN)with a reciprocal space discriminator,which augments simulated data with realistic spatial frequency *** allows the CycleGAN to generate images nearly indistinguishable from real data and provide labels for ML *** showcase our approach by training a fully convolutional network(FCN)to identify single atom defects in a 4.5 million atom data set,collected using automated acquisition in an aberration-corrected scanning transmission electron microscope(STEM).Our method produces adaptable FCNs that can adjust to dynamically changing experimental variables with minimal intervention,marking a crucial step towards fully autonomous harnessing of microscopy big data.

关键词： autonomous adjust network

Material and structural instabilities of single-wall carbon nanotubes

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Acta Mechanica Sinica 2008年第3期24卷 285-288页

作者： J.Wu K.C.Hwang J.Song y.huang FML Department of Engineering MechanicsTsinghua UniversityBeijing 100084China Department of Mechanical Science and Engineering University of Illinois1206 W.Green StreetUrbanaIL 61801USA Department of Civil and Environmental Engineering and Department of Mechanical Engineering Northwestern UniversityEvanstonIL 60208USA

The nonlinear atomistic interactions usually involve softening behavior. Instability resulting directly from this softening are called the material instability, while those unrelated to this softening are called the structural instability. We use the finite-deformation shell theory based on the interatomic potential to show that the tension instability of single-wall carbon nanotubes is the material instability, while the compression and torsion instabilities are structural instability.

关键词： Carbon nanotubes Instability

Mblk-1 regulates sugar responsiveness in honey bee(Apis mellifera)foragers

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Insect Science 2022年第3期29卷 683-690页

作者： Fang Liu Lixian Wu yuan Zhang Qiang Li Liangbin Li Zachary y.huang Hongxia Zhao Guangdong Key Laboratory of Animal Conservation and Resource Utilization Guangdong Public Laboratory of Wild Animal Conservation and UtilizationInstitute of ZoologyGuangdong Academy of SciencesChina yunnan Academy of Biodiversity Southwest Forestry UniversityKunmingYunnan650224China Department of Entomology Michigan State UniversityEast LansingMichiganUSA

Brain transcriptional regulatory network for behavior demonstrates that brain gene expression in the honey bee can be accurately predicted from the expression transcription factors(TFs),but roles for specific TFs are less *** bodies(MBs)are important for learning,memory and sensory integration in the honey bee brain.A TFs,Mblk-1,expressed preferentially in the large-type Kenyon cells of the honeybee MBs is predicted to be involved in brain function by regulating transcription of its target genes in honey ***,its function and the mechanism of regulation in behavior of honey bee is still *** we show that Mblk-1 had significantly higher expression in the brains of forager bees relative to nurse ***-1 was significantly inhibited in bees fed small interfering *** addition,inhibition of Mblk-1 decreased sucrose responsiveness in ***,we determined that Mblk-1 regulated the messenger RNA of *** findings suggest that Mblk-1 may target AmGRl to regulate the sucrose responsiveness of foragers.

关键词： division of labor GRs honey bee Mblk-1 sucrose responsiveness

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《照应现象的跨语言研究》述评

当代语言学 2006年第4期8卷 354-359页

作者： y.huang 李丛禾（述评）不详南京政治学院上海分院外语教研室上海市200433

《照应现象的跨语言研究》（Anaphora：A Cross，Linguistic Study2000）一书是英国牛津大学出版社“类型学和语言学理论”系列丛书之一，是英国雷丁大学黄衍继《照应现象的句法及语用研究》（huang 1994）之后的又一部力作。

关键词：语言研究照应牛津大学出版社述评语言学理论系列丛书语用研究类型学

Techno-economic assessment of pulverized coal boilers and IGCC power plants with CO_(2) capture

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Frontiers of Chemical Science and Engineering 2010年第2期4卷 196-206页

作者： y.huang S.REZVANI D.McILVEEN-WRIGHT N.HEWITT A.MINCHENER J.MONDOL University of Ulster Centre for Sustainable TechnologiesCo.AntrimBT370QBNorthern IrelandUK IEA EPL Gemini House London SW156AAUK

The current studies on power plant technologies suggest that Integrated Gasification Combined Cycle(IGCC)systems are an effective and economic CO_(2) capture technology *** addition,the system in conventional configuration has the advantage of being more“CO_(2) capture ready”than other *** coal boilers(PC)have,however,proven high technical performance attributes and are economically often most practical *** highlight the pros and cons of both technologies in connection with an integrated CO_(2) capture,a comparative analysis of ultrasupercritical PC and IGCC is carried out in this *** technical design,the mass and energy balance and the system optimizations are implemented by using the ECLIPSE chemical plant simulation software *** upon these technologies,the CO_(2) capture facilities are incorporated within the *** most appropriate CO_(2) capture systems for the PC system selected for this work are the oxy-fuel system and the postcombustion scheme using Monoethanolamine solvent scrubber column(MEA).The IGCC systems are designed in two configurations:Water gas shift reactor and Selexol-based *** options generate CO_(2)-rich and hydrogen rich-gas *** the comparative analysis of the technical performance attributes of the above cycles,the economic assessment is carried out using the economic toolbox of ECLIPSE is seamlessly connected to the results of the mass and energy balance as well as the utility *** total cost assessment is implemented according to the stepcount exponential costing method using the dominant factors and/or a combination of ***,based on a set of assumptions,the net present value estimation is implemented to calculate the breakeven electricity selling prices and the CO_(2) avoidance cost.

关键词： integrated gasification combined cycle(IGCC) Oxy-fuel combustion CO_(2)apture super-critical pulverized coal(SPC) amine scrubbing system technoeconomic analysis break-even electricity selling price(BESP)