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COMPOSITION EFFECT ON DRy SLIDING WEAR BEhAVIORS OF Ti-B-N ThIN FILMS

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Acta Metallurgica Sinica(English Letters) 2005年第3期18卷 300-306页

作者： P.Sit y.h.lu h.Chen Z.F.Zhou y.G.Shen K.y.Li DepartmentofPhysicsandMaterialsScience CityUniversityofHongKongKowloonHongKongChina DepartmentofPhysicsandMaterialsScience CityUniversityofHongKongKowloonHongKongChina／／DepartmentofManufacturingEngineeringg：EngineeringManagementCityUniversityofHongKongKowloonHongKongChina DepartmentofManufacturingEngineering＆EngineeringManagement CityUniversityofHongKongKowloonHongKongChina

Friction and sliding wear behaviour of Ti-B-N coatings against AISI440C steel ba ll and WC-6wt%Co ball were studied by using pin-on-disk tribometer along with mi crostructure characterization using optical microscopy (OM), scanning electron m icroscopy (SEM) and X-ray photoelectron spectroscopy (XPS). It is shown that the wear resistance of film depended on the wear mechanism. In the case of AISI440C steel, adhesive wear were pre-dominant and the wear rate increased sharply to a maximum when N content reach ~38at.%. This might be related to the change of fi lm microstructure and phase configuration, so the least adhesive transfer of tri bo-film was observed. If WC-6wt%Co ball was used, less deformation wear debris w as observed, this was responsible for the rise of wear rate. Despite of differen t wear modes, friction coefficients in both cases were found to depend mainly on the formation and the amount of h-BN phase. Elemental analysis by energy disper sive spectroscopy (EDS) and X-ray photoelectron spectroscopy (XPS) revealed that oxygen participated in the wear behavior by reacting with films to form the deb ris comprised of various types of Ti oxide including TiO, TiO2 and Ti2O3 , which increased wear resistance.

关键词： dry sliding wear friction coefficient oxidation Ti-B-N wear

FRACTURE MEChANISM AND MICROMEChANICAL ANALySIS OF POLySyNThETICALLy TWINNED CRySTALS OF γTiAl ALLOyS

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中国有色金属学会会刊:英文版 1999年第S1期9卷 130-137页

作者： y.G.Zhang y.h.lu G.K.hu C.Q.Chen Department of Materials Science and Engineering Beijing University of Aeronautics and Astronautics UnversityBeijing 100083China Department of Applied Mechanics Beijing Institute of TechnologyBeijing 100081China

The fracture behavior and mechanism of PST crystals of a Ti 49%(mole fraction)Al alloy have been studied by using in situ straining and micromechanical calculation. The three dimensional micromechanical model representing the structure of PST crystal has been built, and the stress distribution ahead of the sharp and blunt crack tips either parallel to lamellar interface or perpendicular to the lamellae has been calculated by using finite element method based on linear elasticity of PST crystals. The experimental results show that the fracture behaviors and mechanisms are strongly dependent on the angle of loading axis to the lamellae. The calculation indicates that nucleation and propagation of microcrack along the interfaces are controlled by the normal stress and translamellar microcrack is controlled by shear stress ahead of crack tip.

关键词： TiAl alloy PST crystal fracture behavior mechanism micromechanical model finite element method

The challenges of dealing with promiscuous cytochrome P450 and PXR

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The challenges of dealing with promiscuous cytochrome P450 a...

Axial ultra high cycle fatigue behavior of warm compaction Fe-Cu-Ni-Mo-C sintered material

第九届全国药物和化学异物代谢学术会议

作者： Anthony y.h.lu Department of Chemical Biology Ernest Mario School of PharmacyRutgers UniversityPiscatawayNew JerseyUSA

Unlike classical enzymes,drug-metabolizing enzymes such as cytochrome P450,UDP-glucuronyltransferase,epoxide hydrolase and flavin-containing monooxygenase all exhibit broad substrate specificities,low turnover rates,atypical kinetics and other unusual *** such as pregnane X receptor(PXR),constitutive androstane receptor(CAR) and aromatic hydrocarbon receptor(AhR) responsible for the ind uction of various drug-metabolizing enzymes also have broad substrate *** P450 and PXR are two important proteins intimately involved in drug metabolism. Promiscuous proteins,by definition,are known for diversity,but not for specificity in their interactions with

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Axial ultra high cycle fatigue behavior of warm compaction F...

Rational design of AgGaS/ZnS/ZnS quantum dots with a near-unity photoluminescence quantum yield via double shelling scheme

2012年海峡两岸破坏科学/材料试验学术会议

作者： y.h.lu Z.y.Xiao X.yE y.y.Li School of Mechanical and Automotive Engineering South China University of Technology

Partly pre-alloyed Fe-2Cu-2Ni-1Mo-1C material was fabricated by die-wall lubricated warm *** compacts were sintered at 1120℃for 60 min in a hydrogen-nitrogen protecting *** properties such as hardness and tensile strength were measured. Axial tension-compression ultrasonic fatigue testing specimen was designed by finite element *** behavior when 10～10 cycles was *** showed that fatigue fracture was appeared at more than 10 *** conditional fatigue limit of material was existed. The fatigue strength was 392 MPa,312 MPa,249 MPa,199 MPa and 159 MPa on the corresponding conditions of 10,10,10,10 and 10 cycles,*** fractures were analyzed,and fracture source was located close to the hole near the surface.

关键词： Powder Metallurgy Ultra high Cycle Fatigue Behavior Warm Compaction Fracture

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Journal of Materials Science & Technology 2024年第2期169卷 235-242页

作者： h.X.lu h.Liu Z.Z.Fu y.y.Chen h.Q.Dai Z.hu W.L.Zhang R.Q.Guo Institute for Electric Light Sources School of Information Science and TechnologyFudan UniversityShanghai 200433China Institute of Future Lighting Academy for Engineering and TechnologyFudan UniversityShanghai 200433China yiwu Research Institute of Fudan University YiwuZhejiang 322000China Zhongshan-Fudan Joint Innovation Center Zhongshan 528437China

In this study,a two-step method was used to synthesize highly luminescent AgGaS/ZnS/ZnS quantum dots(QDs).In the first step,an inner ZnS shell was formed via a one-pot method,which resulted in a smaller lattice mismatch between the AgGaS core and the outer ZnS shell,thereby facilitating the formation of a thick outer *** the two-step shelling process,the synthesized AgGaS/ZnS/ZnS QDs showed an excellent photoluminescence quantum yield(PLQy)of 96.4%with a peak wavelength of 508 nm,repre-senting the highest PLQy reported thus far for AgGaS ***,the effect of halogen ions in Zn precursors on the shelling process was *** was proposed that the capacity of halogen ions to coordinate with the QDs influenced the balance between Zn cation diffusion and ZnS shelling ***,the ZnS shelling reaction was dominant when ZnCl_(2)was employed,while Zn cation diffusion was the dominant process under the I^(−)-rich *** work provides insights into the interfacial restructuring during the ZnS shelling and offers a clear map for the tailored synthesis of core/shell QDs.

关键词： AgGaS Quantum dots Photoluminescence Core/shell Alloyed core/shell interface

Trial characteristics and treatment effect estimates in randomized controlled trials of Chinese herbal medicine: A meta-epidemiological study

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Journal of Integrative Medicine 2024年第3期22卷 223-234页

作者： Betty h.Wang ya-li Lin yin-yan Gao Jin-lu Song Lang Qin Ling-qi Li Wen-qi Liu Claire C.W.Zhong Mary y.Jiang Chen Mao Xiao-bo yang Vincent C.h.Chung Irene X.y.Wu Jockey Club School of Public health and Primary Care the Chinese University of Hong KongHong Kong 999077China Xiangya School of Public health Central South UniversityChangsha 410006Hunan ProvinceChina School of Chinese Medicine the Chinese University of Hong KongHong Kong 999077China School of Public health Southern Medical UniversityGuangzhou 510080Guangdong ProvinceChina State Key Laboratory of Dampness Syndrome of Chinese Medicine the Second Affiliated Hospital of Guangzhou University of Chinese MedicineGuangzhou 510120Guangdong ProvinceChina Chinese Medicine Syndrome Research Team the Second Affiliated HospitalGuangzhou University of Chinese MedicineGuangzhou 510120Guangdong ProvinceChina Guangdong Provincial Key Laboratory of Clinical Research on Traditional Chinese Medicine Syndrome Guangzhou 510120Guangdong ProvinceChina hunan Provincial Key Laboratory of Clinical Epidemiology Central South UniversityChangsha 410006Hunan ProvinceChina

Background:Previously published meta-epidemiological studies focused on Western medicine have identified some trial characteristics that impact the treatment effect of randomized controlled trials(RCTs).Nevertheless,it remains unclear if similar associations exist in RCTs on Chinese herbal medicine(ChM).Further,Chinese medicine-related characteristics have not been explored ***:To investigate trial characteristics related to treatment effect estimates on ChM *** strategy:This meta-epidemiological study searched 5 databases for systematic reviews on ChM treatment published between January 2011 and July *** criteria:An eligible systematic review should only include RCTs of ChM and conduct at least one *** extraction and analysis:Two reviewers independently conducted data extraction on general characteristics of systematic reviews,meta-analyses and included *** also assessed the risk of bias of RCTs using the Cochrane risk of bias tool.A two-step approach was used for data *** ratio of odds ratios(ROR) and difference in standardized mean differences (dSMD) with 95%confidence interval (CI) were applied to present the difference in effect estimates for binary and continuous outcomes,***:Ninety-one systematic reviews,comprising 1338 RCTs were *** binary outcomes,RCTs incorporated with syndrome differentiation (ROR:1.23;95%CI:[1.07,1.39]),adopting Chinese medicine formula (ROR:1.19;95%CI:[1.03,1.34]),with low risk of bias on incomplete outcome data (ROR:1.29;95%CI:[1.06,1.52]) and selective outcome reporting (ROR:1.12;95%CI:[1.01,1.24]),as well as a trial size≥100 (ROR:1.23;95%CI:[1.04,1.42]) preferred to show larger effect *** for continuous outcomes,RCTs with Chinese medicine diagnostic criteria (dSMD:0.23;95%CI:[0.06,0.41]),judged as high/unclear risk of bias on allocation concealment (dSMD:-0.70;95%CI:[-0.99,-0.42]),with low risk of bias on incomplete outcome data (dSMD:0.30

关键词： Chinese herbal medicine Randomized controlled trial Risk of bias Meta-epidemiological study Effect estimates

Chinese Expert Consensus on the Diagnosis and Treatment of Adult Dermatomyositis (2022)#

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International Journal of Dermatology and Venereology 2024年第3期7卷 163-173页

作者： Cao h. Chen A.-J. Cui y. Deng D.-Q. Gao X.-h. he y.-L. Kang X.-J. Jin h.-Z. Li C.-X. Li F. Li h.-J. Liao W.-J. Liu X.-M. lu Q.-J. lu y. Pan M. Pan W.-h. Shu X.-M. Sun Q. Tang K.-y. Tao J. Wang y. Xiao T. Zhang F.-R. Zhang h.-L. Department of Dermatology Ruijin Hospital Affiliated Shanghai Jiao Tong University School of Medicine Shanghai 200025 China Department of Dermatology First Affiliated Hospital of Chongqing Medical University Chongqing 400042 China Department of Dermatology China-Japan Friendship Hospital Beijing 100029 China Department of Dermatology The Second Affiliated Hospital of Kunming Medical University Yunnan Kunming 650101 China Department of Dermatology The First Hospital of China Medical University Liaoning Shenyang 110001 China Department of Dermatology Beijing Chaoyang Hospital Affiliated to Capital Medical University Beijing 100020 China Department of Dermatology and Venereology People's Hospital of Xinjiang Uygur Autonomous Region Xinjiang Uygur Autonomous Region Urumqi 830001 China Department of Dermatology State Key Laboratory of Complex Severe and Rare Diseases Peking Union Medical College Hospital Chinese Academy of Medical Science Peking Union Medical College Beijing 100730 China Department of Dermatology First Medical Center PLA General Hospital Beijing 100853 China Department of Dermatology Hainan Hospital of PLA General Hospital Hainan Sanya 572013 China Department of Dermatology Xijing Hospital Air Force Medical University Shaanxi Xi'an 710032 China Department of Dermatology Huazhong University of Science and Technology Union Shenzhen Hospital Guangdong Shenzhen 518052 China hospital for Skin Diseases Institute of Dermatology Chinese Academy of Medical Sciences Peking Union Medical College Jiangsu Nanjing 210042 China Department of Dermatology Jiangsu Province Hospital The First Affiliated Hospital Nanjing Medical University Jiangsu Nanjing 210029 China Department of Dermatology Shanghai Changzheng Hospital Second Affiliated Hospital of Naval Medical University Shanghai 200003 China Department of Rheumatology China-Japan Friendship Hospital Beijing 100029 China Department of Dermatology Qilu Hospital of Shandong Universit

Dermatomyositis, an idiopathic inflammatory myopathy, is characterized by distinctive skin manifestations, proximal muscle weakness, and multiple organ involvement and can be accompanied by malignancies. To provide a reference for dermatologists and clinicians in other relevant fields of clinical practice, experts from the Dermatology Branch of the China International Exchange and Promotion Association for Medical and health Care and the National Clinical Research Center for Dermatologic and Immunologic Diseases developed this consensus on the diagnosis and treatment of adult dermatomyositis using Chinese and international literature and expert advice. © 2024 Wolters Kluwer health. All rights reserved.

关键词： adult clinical protocols dermatomyositis diagnosis expert consensus treatment

Renewable biosynthesis of isoprene from wastewater through a synthetic biology approach:the role of individual organic compounds

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Frontiers of Environmental Science & Engineering 2024年第3期18卷 13-24页

作者： Min yang Xianghui Li Weixiang Chao Xiang Gao huan Wang lu lu State Key Laboratory of Urban Water Resource and Environment School of Civil and Environmental EngineeringHarbin Institute of TechnologyShenzhen 518055China Center for Materials Synthetic Biology CAS Key Laboratory of Quantitative Engineering Biology of CASShenzhen Institute of Synthetic BiologyShenzhen Institutes of Advanced TechnologyChinese Academic of ScienceShenzhen 518000China Institute of Urban Ecology and Environmental Technology School of Materials and Environmental EngineeringShenzhen Polytechnic UniversityShenzhen 518055China

The biosynthesis of isoprene offers a more sustainable alternative to fossil fuel-based approaches,yet its success has been largely limited to pure organic compounds and the cost remains a *** study proposes a waste-to-wealth strategy for isoprene biosynthesis utilizing genetically engineered *** bacteria to convert organic waste from real food *** impact of organic compounds present in wastewater on *** growth and isoprene production was systematically *** results demonstrated that with filtration pretreatment of wastewater,isoprene yield,and production achieved 115 mg/g COD and 7.1 mg/(L·h),***,even without pretreatment,isoprene yield only decreased by~24%,indicating promising ***,maltose,glycerol,and lactate are effective substrates for isoprene biosynthesis,whereas starch,protein,and acetate do not support *** *** optimum C/N ratio for isoprene production was found to be 8:***,augmenting essential nutrients in wastewater elevated the isoprene yield increased to 159 mg/g *** wastewater biosynthesis significantly reduced the cost(44%–53%decrease,p-valuelueh both sugar fermentation and fossil fuel–based *** study introduced a more sustainable and economically viable approach to isoprene synthesis,offering an avenue for resource recovery from wastewater.

关键词： Wastewater Resource recovery Genetic engineering Biosynthesis Isoprene

Surface iodine and pyrenyl-graphdiyne co-modified Bi catalysts for highly efficient CO_(2) electroreduction in acidic electrolyte

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Nano Research 2024年第4期17卷 2381-2387页

作者： Min Zhang Juan Wang Xin Rong Xiu-Li lu Tong-Bu lu MOE International Joint Laboratory of Materials Microstructure Institute for New Energy Materials and Low Carbon TechnologiesSchool of Materials Science and EngineeringTianjin University of TechnologyTianjin 300384China

CO_(2) electroreduction to formic acid/formate would contribute to alleviating the energy and climate *** work reports a Bi-based catalyst derived from the in-situ electroreduction of Bi_(2)O_(2)CO_(3) modified with iodine and pyrenyl-graphdiyne(PGDy)on the surface for efficient electroreduction of CO_(2) in acidic electrolyte,with a high partial current density of 98.71 mA·cm^(-2) and high Faradaic efficiency(FE)>90%over the potential range from^(-1).2 to-1.5 V *** hydrogen electrode(RhE),as well as the long-term operational stability over 240 h without degradation in h-type *** results and density function theory calculations show that the synergistic effect of surface iodine and PGDy is responsible for this active and extremely stable process of CO_(2) electroreduction via lowering the energy barriers for formation of*OChO intermediate,suppressing the competitive hER by enhancing the concentration of both K+and CO_(2) at reaction interface,as well as preventing the dissolution and re-deposition of active Bi atoms on surface during catalytic *** work provides new insight into designing highly active and stable electrocatalysts for CO_(2) reduction.

关键词： CO_(2) reduction electrocatalysis Bi-based catalysts acidic electrolyte