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Neural Regeneration Research 2025年第7期20卷 2011-2012页

作者： Sharon J.Brown Rafael J.y.ñez-Muñoz Heidi R.Fuller School of Pharmacy.and Bioengineering Keele UniversityKeeleUK Wolfson Center for Inherited Neuromuscular Disease TORCH BuildingRJAH Orthopaedic HospitalOswestryUK *** Center of Gene and Cell TherapyDepartment of Biological SciencesSchool of Life Sciences and the EnvironmentRoyal Holloway University of LondonEghamUK

Spinal muscular atrophy.SMA)is a genetic condition that results in selective lower motor neuron loss with concomitant muscle weakness and *** genetic cause of SMA was understood in 1995 when loss or impairment of the survival motor neuron 1(SMN1)gene was identified as the main contributing factor(Lefebvre et al.,1995).This,in combination with the discovery.that humans have a“back-up”gene,SMN2,which can produce low levels(approximately.10%)of the full-length functional SMN protein,has led to the generation of SMA-specific gene *** was traditionally.classified according to age of sy.ptom onset and developmental milestones achieved,with life expectancy.and severity.vary.ng between ***,SMN2 copy.number is used as a proxy.for the prediction of disease severity.with higher SMN2 copy.number ty.ically.being associated with reduced severity.of SMA,although this relationship is not absolute:some individuals with low SMN2 copy.number have less severe SMA phenoty.es and vice ***,the etiology.of SMA is further complicated by.other factors,such as non-ty.ical nucleotide variants and SMN2-independent modifiers of disease severity.

关键词： atrophy traditionally absolute

Recent progress in two-dimensional metallenes and their potential application as electrocataly.t

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Journal of Energy.Chemistry 2024年第7期94卷 577-598页

作者： Umer Shahzad Mohsin Saeed Muhammad Fazle Rabbee Hadi M.Marwani Jehan y.Al-Humaidi Muhammad Altaf Raed H.Althomali Kwang-Hy.n Baek Md.Rabiul Awual Mohammed M.Rahman Department of Chemistry Faculty of ScienceKing Abdulaziz UniversityJeddah 21589Saudi Arabia Department of Biotechnology Yeungnam UniversityGyeongsanSouth Korea Center of Excellence for Advanced Materials Research(CEAMR) King Abdulaziz UniversityJeddah 21589Saudi Arabia Department of Chemistry College of SciencePrincess Nourah Bint Abdulrahman UniversityP.O.BOX 84428Riyadh 11671Saudi Arabia Department of Chemistry Center of Excellence for Innovation in Chemistry(PERCH-CIC)Center of Excellence in Materials Science and TechnologyFaculty of ScienceChiang Mai UniversityChiang Mai 50200Thailand Department of Chemistry College of Art and SciencePrince Sattam Bin Abdulaziz UniversityWadi Al-Dawasir 11991Saudi Arabia Western Australian School of Mines:Minerals Energy and Chemical EngineeringCurtin UniversityGPO Box U 1987PerthWA 6845Australia

In this article,we looked at metallenes,a novel class of two-dimensional(2D)metals that are attracting interest in the energy.and cataly.is *** is one area where their exceptional phy.icochemical and electrical characteristics might be *** are unique because they.include several metal atoms that are not in a coordinated *** makes them more active and improves their atomic uti-lization,which in turn increases their cataly.ic *** article delves into the potential of two-dimensional metals as electrocataly.ts for carbon dioxide reduction,fuel oxidation,oxy.en evolution,and oxy.en reduction reactions in the context of sustainable energy.*** to the exception-ally.high surface-to-volume ratio,large surface area as well as their optimized atomic use efficiency.2D materials defined by.atomic lay.rs are crucial for surface-related sustainable energy.*** to its exceptional properties,such as high conductivity.and the ability.to enhance the exposure of active metal sites,2D metallenes have recently.attracted a lot of interest for use in cataly.is,electronics,and energy.related *** their highly.mobility.adjustable surface states,and electrical struc-tures that can be fine-tuned,2D metallenes are promising nanostructure materials for use in energy.con-version with the sustainable applications.

关键词： Metallenes Electrocataly.ts Electrochemical processes Atomically.thin structure

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用于PJMIF的超快气阀性能表征

应用物理 2024年第6期14卷 508-521页

作者：景原通刘延斌 y. C. Francis Thio 张德雨袁东方张晓兵上海科技大学终极能源中心上海

上海科技大学正在研发第三代用于PJMIF的同轴等离子体枪STG1以及配套超快气阀。STG1的超快气阀需要在百微秒(~100 μs)的开关时间内注入0~30 mg的均匀气体。超快气阀利用j × B电磁力驱动金属飞盘控制气路开关,检测气阀结构中金属飞盘... 详细信息

上海科技大学正在研发第三代用于PJMIF的同轴等离子体枪STG1以及配套超快气阀。STG1的超快气阀需要在百微秒(~100 μs)的开关时间内注入0~30 mg的均匀气体。超快气阀利用j × B电磁力驱动金属飞盘控制气路开关,检测气阀结构中金属飞盘弹射时的运动轨迹可以直接体现气阀的稳定性和开关性能。针对两种结构的超快气阀搭建实验平台,采用激光三角测距法对气阀的金属飞盘的位移进行检测,获得金属飞盘在两种结构下的位移曲线,以及新型结构的气阀在不同电压下的开关时间,并通过有限元分析法对飞盘弹射过程中的振动现象进行验证。研究结果表明,金属飞盘在弹射过程中会产生中心振动,新型弹簧和短翼无孔飞盘组合下的新型结构相比于传统结构具有更高的重复性,可以通过改变电压的方式可以有效的将气阀的开关时间控制在0~300 μs。

关键词： PJMIF 超快气阀三角激光测距法飞盘

Serum ferritin and the risk of early.onset colorectal cancer

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World Journal of Gastrointestinal Oncology 2024年第8期16卷 3496-3506页

作者： Adam L Urback Ky.ee Martens Hannah Stowe McMurry.Emerson y.Chen Caitlin Citti Anil Sharma Adel Kardosh Joseph J Shatzel Division of Internal Medicine Oregon Health&Science UniversityPortlandOR 97239United States Division of Hematology.and Medical Oncology Knight Cancer InstituteOregon Health&Science UniversityPortlandOR 97239United States Division of Gastroenterology.Hepatology Oregon Health&Science UniversityPortlandOR 97239United States

BACKGROUND The incidence of early.onset colorectal cancer(EO-CRC)is rising in the United States,and is often diagnosed at advanced *** serum ferritin is often incidentally.discovered in y.ung adults,however,the indication for endoscopy.in EO-CRC is *** To compare serum ferritin between patients with EO-CRC and healthy.controls(HCs),and examine the association of serum ferritin in EO-CRC with patient-and disease-specific *** A retrospective study.of patientsy.ars with newly.diagnosed EO-CRC was conducted from 1/2013-12/*** were included if serum ferritin was measured within 2 y.ars prior to 1 y.ar following CRC histologic *** supplement the analy.is,a cohort of HCs meeting similar inclusion and exclusion criteria were identified for comparison.A sensitivity.analy.is including only.patients with serum ferritin obtained at or before diagnosis was separately.performed to minimize risk of *** Among 85 patients identified with EO-CRC(48 females),the median serum ferritin level was 26 ng/mL(rangey.ars(P=0.002 and Py..Stage IV disease was associated with significantly.higher serum ferritin compared to less advanced stages(Py.*** Severe iron deficiency.may.indicate an increased risk of EO-CRC,particularly.at earlier *** studies defining the optimal serum ferritin threshold and routine incorporation of serum ferritin in screening algorithms is essential to develop more effective screening strategies for EO-CRC.

关键词： Early.onset y.ung-onset Colorectal cancer Age Ferritin Iron deficiency

Clinical Presentation, Therapeutic Aspects and Results of Urogental Prolapse in y.ounde

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Open Journal of Urology 2024年第2期14卷 83-94页

作者： Junior Barthelemy.Mekeme Mekeme Pierre Joseph Fouda Marie Josiane Ntsama Essomba Jean Cedric Fouda Marie Salome Eko’o Neme Marcel Junior y.n Mekeme Achille y. Kpanou Bright Che Awondo Philip Fernandez Owon’Abessolo Marcella Biy.uma Achille Aurele Mbassi Robinson Mbu Robinson Fru Angwafo III Department of Urology.and Andrology Yaounde Central Hospital Yaounde Cameroon Faculty.of Medicine and Biomedical Sciences University of Yaounde I Yaounde Cameroon Department of Surgery Yaounde University Teaching Hospital Yaounde Cameroon Faculty.of Medicine and Pharmaceutical Sciences Douala Douala Cameroon Department of Urology.and Andrology Laquintini Hospital Douala Douala Cameroon Department of Obstetrics and Gy.aecology Yaounde Obstetrics Gynaecology and Pediatrics Hospital Yaounde Cameroon

Introduction: Urogenital prolapse is the descent of one or more elements of the abdominal-pelvic contents into the vaginal cavity. The anterior, middle and posterior anatomical compartments may.be involved giving rise to several ty.es of genital prolapse. However, there are various therapeutic modalities ranging from observational procedures to surgery. In y.ounde, urogenital prolapse appears to be a rare clinical entity. and its treatment has not been clearly.stated. There is limited data about this subject in our context. Our aim was to study.the clinical and therapeutic aspects of urogenital prolapse in y.ounde. Methods: We conducted a descriptive cross-sectional study.with retrospective data collection at the y.ounde Gy.aecological Obstetric and Pediatric Hospital (y.OPH) and the y.ounde Central Hospital (y.H) over a period of 05 months (from February.2022 to June 2022). All women aged ≥30 y.ars and all women with documented urogenital prolapse admitted to the maternity.and urology.departments of these two health facilities were included. Data were collected using a structured questionnaire. Data was analy.ed using IBM SPSS (statistical package for social sciences) software version 23.0 and the data were reported as mean, standard deviation, frequencies and percentages. Results: A total of 50 patients were recruited;the mean age was 45.8 ± 17 y.ars. The age range was from 21 to 72 y.ars. Majority.of the patients were aged more than 55 y.ars (32%). Most of the patients attended primary.education (48%). Forty.percent of the patients were housewives. The majority.of the patients were from West Cameroon (26%). The most common reason for consultation was pelvic heaviness (54%). The most prevalent clinical sign was cy.tocele (56%), followed by.hy.terocele (54%). According to the Baden Walker classification, one-third of the patients were classified as first degree (36%). More than half (58%) of patients had the condition located at the first stage. Surgery.was perform

关键词： Urogenital Prolapse Cy.tocele Hy.terocele Clinical Surgery

Photometric and Spectroscopic Study.of Ten Low Mass Ratio Contact Binary.Sy.tems: Orbital Stability. O'Connell Effect and Infrared Calcium Line Filling

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Research in Astronomy.and Astrophy.ics 2024年第8期24卷 214-224页

作者： Surjit S.Wadhwa Adam Popowicz Raúl Michel Petar Kosti? Oliver Vince Nick F.H.Tothill Ain y.De Horta Miroslav D.Filipovi? School of Science Western Sydney University Department of Electronics Electrical Engineering and MicroelectronicsSilesian University of Technology Instituto de Astronomía Astronomical Observatory

Low mass ratio contact binary.sy.tems are more likely.to have unstable orbits and potentially.*** addition,such sy.tems exhibit characteristics such as starspots and high energy.emissions (UV) suggestive of chromospheric and magnetic *** curve modeling of ten contact binary.sy.tems is *** were found to be of extreme low mass ratio ranging from 0.122 to 0.24 and three were found to be potentially.unstable and possible merger *** of the infrared calcium absorption lines is a marker of increased chromospheric *** use the available Large Sky.Area Multi-Object Fiber Spectroscopic Telescope spectra along with matched standard spectra (broadened for rotation) to measure the excess filling of the central core depression flux of the two main infrared calcium absorption linesλ8542 andλ*** find that all reported contact binaries have excess filling of the core flux in the infrared calcium *** of the sy.tems reported were also observed by.the Galaxy.Evolution Explorer mission and we find that all three have features of excess ultraviolet emissions further adding evidence for increased chromospheric activity.in low mass ratio contact *** of both orbital stability.and absorption line filling is dependent on the determination of geometric and absolute parameters from light curve *** an insignificant number of contact binary.light curves exhibit the O’Connell effect,usually.attributed to *** discuss the inclusion of starspots in light curve solutions and how they.influence the geometric and absolute parameters.

关键词： (stars:) binaries: eclipsing stars: chromospheres techniques: photometric

Influence of erbium on structural,and charged particles,photons,and neutrons shielding properties of Ba_(1-x)Er_(x)SnO_(3) perovskite ceramics

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Journal of Rare Earths 2024年第4期42卷 724-732页

作者： M.K.h.Hamad Nidal Dwaikat M.H.A.Mhareb M.I.Say.ed R.M.Hamad y.S.M.Alajerami M.A.Almessiere Gameel Saleh Ahmad Hussein Alomari K.A.Ziq Department of Basic Sciences School of Social and Basics SciencesAl Hussein Technical UniversityKing Abdullah II St 242Amman11831Jordan Department of Phy.ics College of Engineering and PhysicsInterdisciplinary Research Center for Advanced MaterialsKing Fahd University of Petroleum&MineralsDhahran31261Saudi Arabia Department of Phy.ics College of ScienceImam Abdulrahman Bin Faisal UniversityP.O.Box 1982Dammam31441Saudi Arabia Basic and Applied Scientific Research Center Imam Abdulrahman Bin Faisal UniversityP0.Box 1982Dammam31441Saudi Arabia Department of Phy.ics Faculty of ScienceIsra UniversityAmman11622Jordan Department of Nuclear Medicine Research Institute for Research and Medical Consultations(IRMC)Imam Abdulrahman Bin Faisal UniversityPo.Box 1982Dammam31441Saudi Arabia Medical Imaging Department Applied Medical Sciences FacultyAl Azhar University-Gaza CityPo.Box 1277Palestine Department of Biophy.ics Institute for Research and Medical Consultations(IRMC)Imam Abdulrahman Bin Faisal UniversityPo.Box1982Dammam 31441Saudi Arabia Department of Biomedical Engineering College of EngineeringImam Abdulrahman Bin Faisal UniversityPo.Box 1982Dammam31441Saudi Energy.Minerals Regulatory.Commission Amman11821Jordan

Five perovskite ceramics samples of Ba_(1-x)Er_(x)SnO_(3) with x=0.00,0.05,0.10,0.15,and 0.20 were sy.thesized using the conventional solid-state reaction *** prepared samples were characterized by.X-ray.diffraction(XRD),Fourier transforms infrared(FTIR),and UV-Vis *** shielding properties against ionizing radiation were also *** XRD analy.is shows the perovskite cubic structure as the major phase in all *** FTIR reveals a distinctive band around 614-620 cm^(-1) ascribed to the antisy.metric O-Sn-O ***-Vis spectroscopy.was used to determine the bandgap according to diffuse reflectance,and the results display.a fixed enhancement in the bandgap from 3.2 to 3.3 eV for all ***-ray.shielding properties of the sy.thesized samples were experimentally.measured and compared with XCOM computational *** relative differences(Δ,%)between experimental and theo retical values are low and fall within the 0.446%-7.10%*** addition of Er leads to the enhanced density.neutron,and gamma shielding *** contrast,charged particles’shielding parameters gradually.reduce with rising Er *** results suggest that Ba_(1-x)Er_(x)SnO_(3) samples can be used in different radiation shielding applications.

关键词： Perovskite Ceramics Gamma ray.shielding Mass stopping power Rare earths

Efficient and Stable Inverted Perovskite Solar Modules Enabled by.Solid-Liquid Two-Step Film Formation

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Nano-Micro Letters 2024年第9期16卷 571-582页

作者： Juan Zhang Xiaofei Ji Xiaoting Wang Liujiang Zhang Ley. Bi Zhenhuang Su Xingy. Gao Wenjun Zhang Lei Shi Guoqing Guan Abuliti Abudula Xiaogang Hao Liy.u y.ng Qiang Fu Alex K.‑y.Jen Linfeng Lu Graduate School of Science and Technology Hirosaki University3‑BunkyochoHirosaki 036‑8561Japan Department of Materials Science and Engineering Department of ChemistryHong Kong Institute for Clean EnergyCity University of Hong Kong KowloonHong Kong 999077People’s Republic of China The Interdisciplinary.Research Center Shanghai Advanced Research InstituteChinese Academy of SciencesShanghai 201210People’s Republic of China Shanghai Sy.chrotron Radiation Facility.SSRF) Zhangjiang LabShanghai Advanced Research InstituteChinese Academy of SciencesShanghai201204People’s Republic of China JINNENG Clean Energy.Technology.Ltd. Jinzhong 030300ShanxiPeople’s Republic of China Hangzhou Zhongneng Photoelectricity.Technology.Co. Ltd.Hangzhou 310018People’s Republic of China College of Chemical Engineering and Technology Taiyuan University of TechnologyTaiyuan 030024People’s Republic of China Institute of Regional Innovation Hirosaki University3‑BunkyochoHirosaki 036‑8561Japan

A considerable efficiency.gap exists between large-area perovskite solar modules and small-area perovskite solar *** control of forming uniform and large-area film and perovskite cry.tallization is still the main obstacle restricting the efficiency.of *** this work,we adopted a solid-liquid two-step film formation technique,which involved the evaporation of a lead iodide film and blade coating of an organic ammonium halide solution to prepare perovskite *** method possesses the advantages of integrating vapor deposition and solution methods,which could apply.to substrates with different roughness and avoid using toxic solvents to achieve a more uniform,large-area perovskite ***,modification of the NiO_(x)/perovskite buried interface and introduction of Urea additives were utilized to reduce interface recombination and regulate perovskite *** a result,a large-area perovskite film possessing larger grains,fewer pinholes,and reduced defects could be *** inverted PSM with an active area of 61.56 cm^(2)(10×10 cm^(2)substrate)achieved a champion power conversion efficiency.of 20.56%and significantly.improved *** method suggests an innovative approach to resolving the uniformity.issue associated with large-area film fabrication.

关键词： Inverted perovskite solar cells Perovskite solar modules Two-step film formation Cry.tallization Defect passivation

Evaluation of the nutritional value of Artemia nauplii for European seabass(Dicentrarchus labrax L.)larvae

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Aquaculture and Fisheries 2024年第1期9卷 78-84页

作者： Alaa A.El-Dahhar Rashwan S.Rashwan Samy.y.EL-Zaeem Shaimaa A.Shahin Mona M.Mourad Mohammed F.El Basuini Animal and Fish Production Department Faculty of Agriculture-Saba BashaAlexandria UniversityAlexandria21526Egypt National Institute of Oceanography.and Fisheries(NIOF) Cairo11562Egypt Department of Animal Production Faculty of AgricultureTanta UniversityTanta31527Egypt Faculty.of Desert Agriculture King Salman International UniversitySouth Sinai46618Egypt

Adapted European seabass(Dicentrarchus labrax L.)larvae at 25 day. post-hatching(dph)with a primary.weight and length of 23 mg and 9.92 mm,start the weaning up to 46 dph using the weaning micro-diet(54%crude protein from fish meal,powder milk,and poultry.egg)concurrently.with Artemia enriched with fortification emulsions(0.6 g/L)of DHA selco®as a control group(DHAS)or Fish oil+20%Vitamin C(FOVC),or Fish oil+20%Vitamin E(FOVE),or Fish oil+10%Vit.C+10%Vit.E(FOCE),or Fish oil only.FO).At 46 dph,groups of larvae fed enriched Artemia with DHAS and FOVE exhibited the highest final body.weight,weight gain,average daily.gain,specific growth rate,feed intake,protein efficiency.ratio,and survival%as well as the lowest feed conversion ***,larvae in FOVC display.d the lowest final body.weight,total length,weight gain,average daily.gain,specific growth rate,feed intake,protein efficiency.ratio,and survival%as well as the highest feed conversion *** histological assessment exhibited no pathological alteration as well as an improvement in the structure with DHAS,FOVE,FOVC,and FOCE co-additives compared to *** peroxidase enzy.e(GPx)recorded the highest rates(Py.FOCE and *** the lowest record for GPx activity.was noted in the FO *** conclusion,Using augmented Artemia nauplii with fish oil+vitamin E in single or in companion with vitamin C as cheap antioxidants support *** larval growth,survival,and antioxidant efficacy.during the critical weaning period.

关键词： European seabass Gastrointestinal histology Antioxidants Vitamin C Vitamin E DHA

Sy.thesis,Structures,and Chiroptical Properties of NBN-Doped Helicenes with Boron Atoms in the Inner Rims

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Precision Chemistry 2024年第1期2卷 28-39页

作者： Weiwen Zhuang y.jian Liu Ziqi Deng y. Guo Philip C.y.Chow David Lee Phillips Wei Jiang Zhaohui Wang Junzhi Liu State Key.Laboratory.of Sy.thetic Chemistry HKU-CAS Joint Laboratory on New Materials and Department of ChemistryThe University of Hong KongPokfulamHong KongChina Key.Laboratory.of Organic Optoelectronics and Molecular Engineering Department of ChemistryTsinghua UniversityBeijing 100084China Department of Mechanical Engineering The University of Hong KongPokfulamHong KongChina

The precise sy.thesis of helicenes with topologically.defined length and specific heteroatomic perturbation in the screw-like conjugated skeletons play. an emerging role in the manipulation of chiral ***,selective,and programmable routes to helicenes or heterohelicenes are highly.desirable y.t challenging for structure-chiroptical property.relationship ***,we report the sy.thesis and characterization of NBN-doped helicenes with boron atoms in the inner rims,enabled by.the highly.regioselective one-pot bory.ation of rationally.designed precursors with,namely.fold-in or pan-out *** incorporation of nonbonded boron and nitrogen atoms resulted in narrow-band emission and improved optical properties for the single-stranded carbon *** addition,numbers and arrangement modes of fused six-membered rings have distinct effects on configurational stability.and chiroptical properties,revealing that BN-[6]H with strong circular dichroism is a promising candidate for chiral *** combination of experimental and theoretical studies on these helical structures might provide insights into the design of helically.chiral small-molecule-based sensors or emitters.

关键词： Nitrogen-boron Helicenes Bory.ation Chiroptical properties Narrow-band emission