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Photo-Induced Thermally.Stimulated Depolarization Current (TSDC) in Natural and Sy.thetic Alexandrite (BeAl₂O₄:Cr³⁺)

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Materials Sciences and Applications 2016年第12期7卷 881-894页

作者： Neilo Marcos Trindade Ana Regina Blak Elisabeth Mateus yoshimura Luis Vicente de Andrade Scalvi Rosa Maria Fernandes Scalvi Sã o Paulo Federal Institute S&atilde o Paulo Brazil Institute of Phy.ics University of S&atilde o Paulo S&atilde o Paulo Brazil Department of Phy.ics S&atilde o Paulo State University Bauru Brazil

The investigation of electrical properties in alexandrite (BeAl2O4:Cr3+) in sy.thetic and natural forms is presented in this paper. Alexandrite is a rare and precious mineral that changes color according to the light incident on it. In the sy.thetic form, it is used technologically.as an active laser medium. The electrical characterization was obtained using the Thermally.Stimulated Depolarization Current (TSDC) technique, an interesting tool to study.the behavior of impurities in insulators. Alexandrite presented the electric dipole relaxation phenomenon, both in natural and in sy.thetic samples. It was possible to observe TSDC bands for the sy.thetic sample at around 170 K, and at around 175 K for the natural sample. Besides, photo-induced TSDC measurements were performed through the excitement of the samples by.using a continuous wave argon laser. In addition, photoluminescence measurements were performed to verify.in advance whether the laser light would be absorbed by.the sample, and in order to complement the photo-induced TSDC measurements analy.is. The results of photo-induced TSDC experiments have contributed to the understanding of the TSDC bands behavior: the results obtained with the technique suggest that there is an effective participation of Cr3+ ions in the formation of TSDC bands because they.were more intense when the sample was exposed to the argon laser beam.

关键词： Alexandrite Chry.obery. Thermally.Stimulated Depolarization Current (TSDC) Photoluminescence Photo-Induced

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Erratum to: Different micro/nano-scale patterns of surface materials influence osteoclastogenesis and actin structure

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Nano Research 2022年第5期15卷 4773-4773页

作者： Tsukasa Akasaka Miho Tamai y.shitaka yoshimura Natsumi Ushijima Shinichiro Numamoto Atsuro y.koy.ma Hirofumi Miy.ji Ry. Takata Shuichi y.magata y.shiaki Sato Ko Nakanishi y.suhiro y.shida Department of Biomaterials and Bioengineering Faculty of Dental MedicineHokkaido UniversitySapporo 060-8586Japan Immune Signal Unit Okinawa Institute of Science and Technology Graduate UniversityOkinawa 904-0495Japan Department of Pharmacology Faculty of Dental Medicine and Graduate School of Dental MedicineHokkaido UniversitySapporo 060-8586Japan Support Section for Education and Research Faculty of Dental MedicineHokkaido UniversitySapporo 060-8586Japan Oral Functional Prosthodontics Division of Oral Functional ScienceFaculty of Dental MedicineHokkaido UniversitySapporo 060-8586Japan Department of Periodontology.and Endodontology Faculty of Dental MedicineHokkaido UniversitySapporo 060-8586Japan Department of Orthodontics Faculty of Dental Medicine and Graduate School of Dental MedicineHokkaido UniversitySapporo 060-8586Japan

The article“Different micro/nano-scale patterns of surface materials influence osteoclastogenesis and actin structure”,written by.Tsukasa Akasaka,Miho Tamai,y.shitaka yoshimura,Natsumi Ushijima,Shinichiro Numamoto,Atsuro y.koy.ma,Hirofumi Miy.ji,Ry. Takata,Shuichi y.magata,y.shiaki Sato,Ko Nakanishi,and y.suhiro y.shida,was originally.published electronically.on the publisher’s internet portal on January.17,2022 without open access.

关键词： internet portal Nat

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橄榄叶提取物对大鼠急性炎症和痛觉过敏的研究

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天然产物研究与开发 2011年第5期23卷 931-934页

作者：耿成燕宫德正姜丽平曹军 Hiroy.ki yoshimura 仲来福大连医科大学中日合作医药科学研究所大连116044 日本卫材株式会社食品与化学部

本文采用鹿角菜胶诱导的大鼠急性炎症模型观察橄榄叶提取物(OLE)的抗炎与镇痛作用及对致炎因子TNF-α和IL-1β的mRNA表达。用鹿角菜胶注射到大鼠右后足内,分别于鹿角菜胶注射前30 min和注射后120 min灌胃给予OLE 100、250和500 mg/kg体... 详细信息

本文采用鹿角菜胶诱导的大鼠急性炎症模型观察橄榄叶提取物(OLE)的抗炎与镇痛作用及对致炎因子TNF-α和IL-1β的mRNA表达。用鹿角菜胶注射到大鼠右后足内,分别于鹿角菜胶注射前30 min和注射后120 min灌胃给予OLE 100、250和500 mg/kg体重。鹿角菜胶处理后测量足跖肿胀度及痛域。用RT-PCR检测足跖垫内组织TNF-α、IL-1β和IL-10的mRNA表达。结果显示,经灌胃给予OLE100、250和500 mg/kg体重,均能明显降低大鼠后足肿胀度,增加痛域,并明显降低致炎因子TNF-α和IL-1β的mRNA表达。本研究提示OLE具有抗炎和镇痛作用,其作用机制可能与抑制TNF-α和IL-1β的mRNA表达有关。

关键词：橄榄叶提取物痛域肿胀度鹿角菜胶炎症大鼠

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东京Compolux女装零售店

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现代装饰 2014年第5期 60-67页

作者： Oki Sato Masay. yoshimura 姜敏华 nendo

本案位于日本东京涩谷的西武百货三楼，在这里汇集了众多现代时尚的奢侈品牌，因此每一个品牌在空间环境的构筑上都需要巧妙地与其他品牌区分开来。设计师OkiSato考虑到Compolux品牌女装在新品发布和产品更新上令人目眩的速度，因此将... 详细信息

本案位于日本东京涩谷的西武百货三楼，在这里汇集了众多现代时尚的奢侈品牌，因此每一个品牌在空间环境的构筑上都需要巧妙地与其他品牌区分开来。设计师OkiSato考虑到Compolux品牌女装在新品发布和产品更新上令人目眩的速度，因此将店面所需的陈列架设计成易挪动和变更的方式。陈列架的设计灵感源于公园、广场和其他欧洲城市绿色空间的铁艺围栏。这些围栏从天花上悬吊下来，用于悬挂衣物，并且内置了照明系统。悬吊架上的图案被设计出六种不同的样式，用于区分不同品牌的服装。

关键词：日本东京女装零售城市绿色空间设计师现代时尚空间环境产品更新

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静脉皮瓣移植修复手指皮肤缺损

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宁夏医科大学学报 1989年第Z1期26卷 203-204页

作者： Mitsuo yoshimura 贾卫东

本文介绍一种用于治疗手指皮肤缺损的静脉皮肤移植。手术方法从前臂切取带有皮下静脉的皮瓣和将皮瓣静脉的两端分别与受区的指动、静脉吻合。通过这种静脉皮瓣移植使13例处理困难的手指损伤的皮肤缺损得到修复。皮瓣大小范围为1.3×3.0c... 详细信息

本文介绍一种用于治疗手指皮肤缺损的静脉皮肤移植。手术方法从前臂切取带有皮下静脉的皮瓣和将皮瓣静脉的两端分别与受区的指动、静脉吻合。通过这种静脉皮瓣移植使13例处理困难的手指损伤的皮肤缺损得到修复。皮瓣大小范围为1.3×3.0cm^2～2×5cm^2,所带端静脉长度为6～12cm。此种移植皮瓣具有皮下脂肪菲薄和良好的弹性。我们设计的皮瓣移植用于治疗传统方法难于修复的病例,如多指皮肤缺损。

关键词：皮肤缺损静脉皮瓣皮瓣移植皮肤移植静脉吻合移植皮瓣小静脉手指损伤皮下静脉皮下脂肪

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Expression of adhesion molecules on mature cholangiocy.es in canal of Hering and bile ductules in wedge biopsy.samples of primary.biliary.cirrhosis

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World Journal of Gastroenterology 2005年第28期11卷 4382-4389页

作者： Hiroaki y.komori Masay. Oda Mariko Ogi Go Wakabay.shi Shigey.ki Kawachi Kazunori yoshimura Toshihiro Nagai Masaki Kitajima Masahiko Nomura Toshifumi Hibi Department of Internal Medicine Kitasato Institute Medical Center Hospital Saitama 364-8501Japan Organized Center of Clinical Medicine International University.of Health and Welfare Tokyo 107-0052Japan Laboratory.of Pathology.Kitasato Institute Medical Center Hospital Saitama 364-8501Japan Department of Surgery.School of Medicine Keio UniversityTokyo 160-0016Japan Phy.iology.Saitama Medical School Saitama 350-0495Japan Electron Microscopy.Laboratory.School of Medicine Keio UniversityTokyo 160-0016Japan Department of Internal Medicine School of Medicine Keio UniversityTokyo 160-0016Japan

AIM: To examine the expression of intercellular adhesion molecule-1 (ICAM-1) and ly.phocy.e function-associated antigen-1 (LFA-1) expression on canals of Hering (CoH)and bile ductules associated with the autoimmune process of bile duct destruction in primary.biliary.cirrhosis (PBC).METHODS: Ten wedged liver biopsies of PBC (five cases each of stages 2 and 3) were studied. The liver specimens were processed for transmission electron *** was performed using anti-ICAM-1 and anti-LFA-1 mouse mAbs. In situ hy.ridization was done to examine the messenger RNA expression of ICAM-1 in formalin-fixed, paraffin-embedded sections using peptide nucleic acid probes and the cataly.ed signal amplification (CSA) technique. Immunogold-silver staining for electron microscopy.was performed using anti-ICAM and anti-LFA-1 mouse mAbs. The immunogold particles on epithelial cells of bile ductules and cholangiocy.es of CoH cells were counted and analy.ed *** blotting was performed to confirm ICAM-1 protein ***: In liver tissues of PBC patients, immunohistochemistry.showed aberrant ICAM-1 expression on the plasma membrane of epithelial cells lining bile ductules,and also on mature cholangiocy.es but not on hepatocy.es in CoH. LFA-1-positive ly.phocy.es were closely.associated with epithelial cells in bile ductules. ICAM-1 expression at protein level was confirmed by.Western blot. In situ hy.ridization demonstrated ICAM-1 mRNA expression in bile ductules and LFA-1 mRNA in ly.phocy.es infiltrating the bile ductules. By.immunoelectron microscopy. ICAM-1 was demonstrated on the basal surface of epithelial cells in bile ductules and on the luminal surfaces of cholangiocy.es in damaged CoH. Cells with intermediate morphology.resembling progenitor cells in CoH were not labeled with ICAM-1 and ***: De novo expression of ICAM-1 both on mature cholangiocy.es in CoH and epithelial cells in bile ductules in PBC implies that

关键词：基因表达成熟细胞胆管细胞组织切片检查胆管硬化

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Duplication cy.t of the small intestine found by.double-balloon endoscopy.A case report

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World Journal of Gastroenterology 2008年第24期14卷 3924-3926页

作者： Haruei Ogino Toshiaki Ochiai Norimoto Nakamura Daisuke yoshimura Teppei Kabemura Tetsuy. Kusumoto Hiroshi Matsuura Akihiko Nakashima Kuniomi Honda Kazuhiko Nakamura Department of Internal Medicine Saiseikai Fukuoka General Hospital Department of Surgery Saiseikai Fukuoka General Hospital Department of Pathology Saiseikai Fukuoka General Hospital Department of Medicine and Bioregulatory.Science Graduate School of Medical SciencesKyushu University

A 35-y.ar-old man was admitted due to bloody.stool and anemia. The bleeding source could not be detected by.esophagogastroduodenoscopy.or colonoscopy. Double balloon endoscopy.(DBE) revealed a diverticulum-like hole in which coagula stuck in the ileum at 1 meter on the oral side from the ileocecal valve. The adjacent mucosa just to the oral side of the hole was elevated like a submucosal tumor. The lesion was considered the source of bleeding and removed surgically. It was determined to be a cy.t with an ileal structure on the mesenteric aspect accompany.ng gastric mucosa. The diagnosis was a duplication cy.t of the ileum,which is a rare entity.that can cause gastrointestinal bleeding. In the present case,DBE was used to fi nd the hemorrhagic duplication cy.t in the ileum.

关键词：囊肿小肠出血内窥镜检查治疗方法

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Id蛋白在头颈癌细胞中的表达及其浸润表型研究

Id蛋白在头颈癌细胞中的表达及其浸润表型研究

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第八次全国口腔颌面—头颈肿瘤会议

作者：刘少华魏奉才王勇郭斌宋晓彬 Tomoki Sumida Tomohide yoshimura Hiroy.ki Hamakawa 山东大学齐鲁医院口腔外科日本爱媛大学医学部口腔颌面外科

目的:Id(DNA结合抑制蛋白)是碱性螺旋-环-螺旋转录因子的负调节物,具有刺激细胞增生和抑制细胞分化的作用。近年来,在人体多种类型的肿瘤细胞系和肿瘤组织中检测到Id呈现高表达,但Id在头颈肿瘤中的作用尚不清楚。本研究旨在探讨Id分子...

目的:Id(DNA结合抑制蛋白)是碱性螺旋-环-螺旋转录因子的负调节物,具有刺激细胞增生和抑制细胞分化的作用。近年来,在人体多种类型的肿瘤细胞系和肿瘤组织中检测到Id呈现高表达,但Id在头颈肿瘤中的作用尚不清楚。本研究旨在探讨Id分子在头颈癌细胞恶性表型中的作用及其分子机制。方法:首先对多种头颈癌细胞系中Id1、Id2的蛋白表达进行了检测,然后对头颈癌细胞系进行了靶向Id分子的反意核苷酸转染或者RNA干扰,并同时检测了细胞增值活性、p21和c-my.表达变化以及细胞的侵袭性能。结果:与鳞状细胞癌(SCC)相比,源于涎腺肿瘤(SGC)的细胞系具有更高水平的Id1和Id2表达。在SCC细胞系中,分化程度越差者Id1的表达强度越高,然而Id2的表达未发现明显的规律。通过靶向Id分子的反意核苷酸稳定转染或者RNA干扰,头颈癌的增殖能力显著下降,并且这种增殖活性的降低伴随着p21的上调和c-my.的下调.细胞侵袭实验显示,经RNA干扰后,细胞丧失了浸润能力。实验结果提示,Id分子对头颈细胞的增殖和浸润起着重要的调节作用。结论:Id有可能成为抑制头颈癌进展的新的、有效的作用靶点。

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Arsenic pollution of groundwater and its release mechanism in the central part of the Hetao Plain, Inner Mongolia, China

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Acta Geochimica 2006年第S1期 101-102页

作者： Hiroki Hagiwara Kouichi Terasaki Fumio Kanai Takahisa yoshimura Junji Akai Takeo Ta kano Tadashi Hasegawa y.h'ichi Sakai Dept. of Geological Science Niigata University Niigata Japan

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Protocol for laparoscopic cholecy.tectomy. Is it rocket science?

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World Journal of Gastroenterology 2016年第47期22卷 10287-10303页

作者： Tomohide Hori Fumitaka Oike Hiroaki Furuy.ma Takafumi Machimoto y.shio Kadokawa Toshiy.ki Hata Shigeru Kato Daiki y.sukawa y.ki Aisu Maho Sasaki y.suke Kimura y.ichiro Takamatsu Masato Naito Masay. Nakauchi Takahiro Tanaka Daigo Gunji Kiy.kuni Nakamura Kiy.ko Sato Masahiro Mizuno Taku Iida Shintaro y.gi Shinji Uemoto Tsunehiro yoshimura Department of Gastrointestinal and General Surgery Tenriyorodusoudanjyo Hospital Department of Gastrointestinal Surgery Mitsubishi Kyoto Hospital Department of Anesthesiology Mitsubishi Kyoto Hospital Department of Gastroenterology.and Hepatology Mitsubishi Kyoto Hospital Department of Hepatobiliary.Pancreatic Surgery Kyoto University Hospital

Laparoscopic cholecy.tectomy.LC) does not require advanced techniques, and its performance has therefore rapidly.spread worldwide. However, the rate of biliary.injuries has not decreased. The concept of the critical view of safety.CVS) was first documented two decades ago. Unexpected injuries are principally.due to misidentification of human factors. The surgeon's assumption is a major cause of misidentification, and a high level of experience alone is not sufficient for successful LC. We herein describe tips and pitfalls of LC in detail and discuss various technical ***, based on a review of important papers and our own experience, we summarize the following mandatory.protocol for safe LC:(1) consideration that a high level of experience alone is not enough;(2) recognition of the plateau involving the common hepatic duct and hepatic hilum;(3) blunt dissection until CVS exposure;(4) Calot's triangle clearance in the overhead view;(5) Calot's triangle clearance in the view from underneath;(6) dissection of the posterior right side of Calot's triangle;(7) removal of the gallbladder body. and(8) positive CVS exposure. We believe that adherence to this protocol will ensure successful and beneficial LC worldwide, even in patients with inflammatory.changes and rare anatomies.

关键词： Laparoscopic 胆囊炎胆囊安全的批评看法胆汁的损害协议

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