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Open Journal of Endocrine and Metabolic Diseases 2015年第10期5卷 131-137页

作者： Miy.ko Mochizuki Emi Hay.shi Atsushi yoshimura y.ko Toy.da Lin Mei Noboru Hasegawa Ky.to Bunky. Junior College Kyoto Japan Department of Health and Nutrition Gifu Women’s University Gifu Japan Material Science and Engineering Nagoya Institutes of Technology Nagoya Japan School of Food and Biological Engineering Jiangsu University Zhenjiang China Department of Health and Medical Sciences Ishikawa Prefectural Nursing University Ishikawa Japan

We studied the effects of exercise on muscle mitochondria, and lipid and gly.ogen content in non-alcoholic steatohepatitis (NASH) model rats. Male Sprague-Dawley.rats were randomly.separated into 3 groups: the control group was fed standard chow;the NASH group was fed a methionine-choline-deficient high-fat diet (MCD);the NASH-exercise group was fed the MCD and exercised three times a week. Exercise training consisted of continuous running for thirty.minutes at a 13 m/min, 6° slope on a motor-driven rodent treadmill for 6 weeks. Mitochondria content in NASH group decreased in the both fiber ty.es compared with those of the control group. As compared between the NASH and NASH-exercise groups, however, exercise not only.promoted significant improvements in liver fibrosis and cirrhosis and trigly.eride (TG) content but also increased mitochondria content in ty.e I muscle fiber in particular. These data suggest that exercise improved hepatic steatosis in NASH model rats and can prevent the progression of NASH.

关键词： Metabolic Disease Non-Alcoholic Steatohepatitis Intramuscular Lipid Trigly.eride Gly.ogen Histopathological Fiber Ty.es Aerobic Exercise

DETERMINATION OF DIFFUSION COEFFICIENT OF LITHIUM IN SILICON By.THE USE OF LI+ SENSITIVE W/WO3 ELECTRODE

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DETERMINATION OF DIFFUSION COEFFICIENT OF LITHIUM IN SILICON...

Numerical Analy.is of Temperature Distributions in Single Cell of Poly.er Electroly.e Fuel Cell when Operated in Elevated Temperature Range

第十一届北京分析测试学术报告会暨展览会(BCEIA2...

作者： Tsutomu TAKAMURA Junji SUZUKI Kazutaka yoshimura Ky.ichi SEKINE Department of Applied Chemistry Harbin Institute of Technology Department of Chemistry Rikkyo University

＜正＞Due to the lack of trustable data on the diffusion coefficient of Li in silicon at room temperature we intended to provide a novel method for the determination,which will assist for the designing of more favorab...

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Journal of Energy.and Power Engineering 2017年第6期11卷 393-408页

作者： Akira Nishimura Kanji Patoriki Zamami Masato yoshimura Masafumi Hirota Mohan Lal Kolhe Division of Mechanical Engineering Graduate School of Engineering Mie University Tsu-city Mie 514-8507 Japan Faculty.of Engineering and Science University of Agder P.O. Box 422 Kristiansand NO. 4604 Norway

Peculiar Concentration Dependence of H/D Exchange Reaction in 1-Buty.-3-methy.imidazolium Tetrafluoroborate-D<sub>2</sub>O Mixtures

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Open Journal of Phy.ical Chemistry 2011年第3期1卷 70-76页

作者： Hiroshi Abe Naohiro Hatano y.suke Ima Souichi Ohta Akio Shimizu y.kihiro yoshimura 不详

We have investigated the H/D exchange reaction between heavy.water and an ionic liquid, 1-buty.-3-methy.-imidazolium tetrafluoroborate ([bmim][BF4]), throughout the whole concentration region as a function of D2O mol% at room temperature. We expected that the extent of the H/D reaction would increase linearly.with increasing content of D2O, but the results show an extended N-shaped behavior having a small maximum at around 40 mol% and the reaction becomes very.slow at a specific concentration around 80 mol%. We found that this non-linear concentration dependence correlates with the pD dependence of the solutions.

关键词： H/D Exchange Reaction pD NMR Ionic Liquid

DEVELOPMENT OF TRAy.Ty.E CLEARANCE LEVEL MONITOR,WHICH CAN MEASURE CONCENTRATION AND SURFACECONTAMINATION SIMULTANEOUSLy

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DEVELOPMENT OF TRAY TYPE CLEARANCE LEVEL MONITOR,WHICH CAN M...

High expressions of caveolins on the proliferating bile ductules in primary.biliary.cirrhosis

第十三届国际核工程大会

作者： Tetsuo Goto y.kio yoshimura y.mamoto Shuuji Makino Shunichiro Isogo Engineering Center Toshiba Corporation Isogo Engineering Center Toshiba Corporation Isogo Engineering Center Toshiba Corporation Isogo Engineering Center Toshiba Corporation

＜正＞ 1 INTRODUCTIONThe clearance levels are defined as "the values expressed in terms of activity.concentrations at or below which objects may.be released from regulatory.control." Establishment of regulations for the clearance levels is now considering in Japan. The measurement of the clearance levels is required to measure radioactivity.concentration contained in waste, which is generated during dismantling of nuclear buildings and facilities accurately.and speedy. On the other side, surface contamination measurement is

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World Journal of Gastroenterology 2005年第24期11卷 3710-3713页

作者： Hiroaki y.komori Masay. Oda Go Wakabay.shi Masaki Kitajima Kazunori yoshimura Masahiko Nomura Toshifumi Hibi Department of Internal Medicine Organized Center of Clinical Medicine Department of Surgery Department of Phy.iology

AIM: An increase in bile ductular structures is observed in diverse human liver diseases, especially.in primary.biliary.cirrhosis (PBC). These structures harbor the progenitor cell component of the liver. Caveolins are cholesterol-binding proteins involved in the regulation of several intracellular processes including cholesterol transport. This study.aims to examine the role of caveolin in ***: Immunohistochemical and Western blottingstudies were performed on human liver specimens obtained from patients with PBC and normal liver samples. The expression of caveolin (CAV)-1 and -2 was determined using specific ***: In normal liver, scanty.immunostaining for CAV1 and -2 was observed in bile ductules. In PBC liver samples, the expression levels of CAV-1 and -2 were increased on proliferating bile ductules especially.in stage 3 cases, but was sparse on interlobular bile duct in stage 1 specimens. Especially. the regenerating bile ductules at the interface of portal tracts and necrotic areas were immunostained intensely.for CAV-1 and -2. These phenomena were confirmed by.Western ***: The present results demonstrate increased expression of caveolins in proliferating bile ductules in PBC, which may.be related to the homeostasis of cholesterol transport in regenerating bile ductules in PBC liver.

关键词：基因表达胆管原发性胆硬化胆固醇

胞嘧啶脱氨酶基因修饰神经干细胞及其表达的离体实验研究

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第三军医大学学报 2003年第11期25卷 945-947页

作者：吕胜青刘运生杨辉何家全王彬 Ichiro yoshimura 第三军医大学附属新桥医院神经外科重庆400037 中南大学湘雅医院神经外科长沙410008 DepartmentofUrology NationalDefenseMedicalCollege32NamikiTokorozawa

目的　探讨胞嘧啶脱氨酶 (Cy.imidinedeaminase ,CD)基因修饰神经干细胞及其基因表达。方法　通过构建真核表达质粒pCMVCD ,限制性内切酶消化鉴定后 ,采用Lipofectamine 2 0 0 0脂质体介导法转染新生大鼠室管膜下区神经干细胞 (Neuralst... 详细信息

目的　探讨胞嘧啶脱氨酶 (Cy.imidinedeaminase ,CD)基因修饰神经干细胞及其基因表达。方法　通过构建真核表达质粒pCMVCD ,限制性内切酶消化鉴定后 ,采用Lipofectamine 2 0 0 0脂质体介导法转染新生大鼠室管膜下区神经干细胞 (Neuralstemcells ,NSCs) ,G418筛选阳性克隆 ,加入不同浓度的 5 氟胞嘧啶 ( 5 Flourocy.osine ,5 FC) ,MTT比色法测定NSCs的生存率。结果　本实验成功地培养并鉴定了神经干细胞 ,并将CD基因成功地转染了神经干细胞 ,G418阳性NSCs对低浓度 5 FC高度敏感。

关键词：胞嘧啶脱氨酶基因转染基因表达神经干细胞

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HALSUIT男装精品概念店

中国建筑装饰装修 2012年第7期 160-163页

作者： Masay. yoshimura

Haruy.ma公司提供种类繁多的西装、衬衫和领带等男装产品,多种选择是其优势之一,但同时顾客也很容易被选项的数量淹没,觉得很难选到最佳搭配的西装,等待的家人也会觉得无趣,

关键词：男装精品最佳搭配西装

Risk of coronary.arterial lesions in immunoglobulin resistant Kawasaki disease

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Open Journal of Pediatrics 2012年第1期2卷 38-41页

作者： Hirotaro Ogino Kazunari Kaneko Takamichi Uchiy.ma Ken yoshimura Masay.ki Teraguchi y.sikazu Nakamura Department of Pediatrics Kansai Medical University Osaka Japan Department of Public Health Jichi Medical University Tochigi Japan

Objective: High-dose intravenous immunoglobulin (IVIG) decreases the risk for development of coronary.arterial lesions (CAL) in Kawasaki disease (KD) while patients resistant to IVIG have higher risk. This study.is aimed to investigate an additional therapy.affects the risk for CAL in IVIG resistant KD. Design: The information from 11,510 children with KD was collected by.the nationwide survey.(2003-2004) in Japan. The secondary.therapeutic strategies for IVIG resistant KD were an additional IVIG dose, steroids or both. The incidence of CAL was compared among 4 groups: G1, children responded to initial IVIG;G2, IVIG resistant patients receiving an additional IVIG dose;G3, IVIG resistant patients receiving additional steroids;G4, IVIG resistant patients receiving an additional IVIG dose plus steroids. CAL was assessed at 30th day.of illness using ultrasound echocardiography. Results: 2229 patients (19.4%) were resistant to initial IVIG. Incidence of CAL was significantly.lower in children responding to initial IVIG than in IVIG resistant patients (1.9% and 11.0%, respectively.odd’s ratio 6.3). The incidences of CAL in an each additional therapy.group were as follows: G2: 6.7%, G3: 9.7%, G4: 22.2%. The risk for CAL was significantly.higher in G4 as compared with G2 and G3. Giant aneury.mal formation (GA) was more frequently.developed in G3 and G4 consisting of the patients receiving steroids (G1: 0.03%, G2: 0.63%, G3: 4.3%, G4: 3.7%). Conclusion: The incidence of CAL was considerably.high in IVIG resistant KD and an additional therapy.by.steroids may.increase the risk for GA.

关键词： Kawasaki Disease Immunoglobulin Resistance Additional Treatment Coronary Arterial Lesions Steroids

广州管圆线虫病所致嗜酸性细胞性脑膜脑炎18例临床分析

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Chinese Medical Journal 2002年第9期115卷 1312-1315页

作者：王小同黄汉津董其谦林燕王宗敏李方去 y.kifumi Nawa Kentars yoshimura 温州医学院附属第二医院浙江温州325000 日本宫崎医科大学寄生虫学研究室日本宫崎市889 日本秋田大学医学部寄生虫学研究室日本010

目的提高临床医师对广州管圆线虫病的认识. 方法分析18例广州管圆线虫病所致嗜酸粒细胞性脑膜脑炎的临床特征及实验室、流行病学调查资料. 结果发病前均有生食淡水螺肉史,潜伏期1-25天.以头痛、躯体痛为主要表现,头痛剧烈而脑膜刺激征... 详细信息

目的提高临床医师对广州管圆线虫病的认识. 方法分析18例广州管圆线虫病所致嗜酸粒细胞性脑膜脑炎的临床特征及实验室、流行病学调查资料. 结果发病前均有生食淡水螺肉史,潜伏期1-25天.以头痛、躯体痛为主要表现,头痛剧烈而脑膜刺激征不明显.周围血象、脑脊液中嗜酸粒细胞明显增高,血清广州管圆线虫抗体阳性(ELISA法).头颅CT正常,2例磁共振(MR)检查呈斑片状异常信号,脑电图α波变慢.用阿苯哒唑、氟美松治疗效果好,预后佳. 结论广州管圆线虫病是嗜酸粒细胞性脑膜脑炎的主要病因之一.

关键词：广州管圆线虫病嗜酸性细胞性脑膜脑炎圆线目感染脑膜脑炎