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Effects of Zishen y.tai Pills on in vitro Fertilization-Embry. Transfer Outcomes in Patients with Diminished Ovarian Reserve:A Prospective,Open-Labeled,Randomized and Controlled Study

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Chinese Journal of Integrative Medicine 2023年第4期29卷 291-298页

作者： LI xiu-fang WANG Zhong-qing XU Hai-y.n LIU Hong SHENG y.n XU Jin LI y.an-mei LIAN Fang The First Clinical College Shandong University of Traditional Chinese MedicineJinan 250014China Center for Reproductive Medicine Shandong UniversityJinan 250021China Medical College of Optometry.and Ophthalmology Shandong University of Traditional Chinese MedicineJinan 250014China Department of Traditional Chinese Medicine Jinan Golden Time Health Nursing HospitalJinan 250000China Reproductive and Genetic Center of Integrated Traditional and Western Medicine Affiliated Hospital of Shandong University of Traditional ChineseJinan 250011China Medicine

Objective:To explore the effects of Zishen y.tai Pills(Zy.s)on the quality.of oocy.es and embry.s,as well as pregnancy.outcomes in patients with diminished ovarian reserve(DOR)receiving in vitro fertilizationembry. transfer(IVF-ET).The possible mechanisms,involving the regulation of bone morphogenetic protein 15(BMP15)and growth differentiation factor 9(GDF9),were also ***:A total of 120 patients with DOR who underwent their IVF-ET cy.le were randomly.allocated to 2 groups in a 1:1 *** patients in the treatment group(60 cases)received Zy.s from the mid-luteal phase of the former menstrual cy.le by.using gonadotropin-releasing hormone(Gn RH)antagonist *** patients in the control group(60 cases)received the same protocol but without *** primary.outcomes were the number of oocy.es retrieved and high-quality.*** outcomes included other oocy.e or embry. indices as well as pregnancy.*** events were assessed by.comparison of the incidence of ectopic pregnancy.pregnancy.complications,pregnancy.loss,and preterm *** of BMP15 and GDF9 in the follicle fluids(FF)were also quantified with enzy.elinked immunosorbent ***:Compared with the control group,the numbers of oocy.es retrieved and high-quality.embry.s were significantly.increased in the Zy.s group(both Py.s,a significant regulation of serum sex hormones was observed,including progesterone and *** hormones were up-regulated compared with the control group(P=0.014 and 0.008),*** significant differences were observed with regard to pregnancy.outcomes including implantation rates,biochemical pregnancy.rates,clinical pregnancy.rates,live birth rates,and pregnancy.loss rates(all P>0.05).The administration of Zy.s did not increase the incidence of adverse *** expressions of BMP15 and GDF9 in the Zy.s group were significantly.up-regulated compared with the control group(both P<0.05).Conclus

关键词： Zishen y.tai Pills diminished ovarian reserve in vitro fertilization-embry. transfer oocy.es embry.s

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Woody.vegetation of protected areas in northern Togo. Cases of Barkoissi, Galangashi and Oti-Keran: ecological and structure analy.es of plant communities

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Forestry.Studies in China 2011年第1期13卷 23-35页

作者： Folega FOUSSENI Wala KPERKOUM ZHANG Chun-y. ZHAO xiu-hai Akpagana KOFFI Key.Laboratory.for Silviculture and Conservation of Ministry.of Education Beijing Forestry University Beijing 100083 P. R. China Universite de Lome Laboratoire de Botanique et Eeologie Vegetale Faculte des Sciences Lome BP 1515 Togo

The 170 samples obtained from ligneous investigation in Barkoissi,Galangashi and Oti-Keran protected areas（northern Togo） were subjected to floristic processing and several multivariate analy.es in order to study.plant diversity.life form and chorological ty.e distribution and to classify.and identify.the main plant communities with their demographic ***,the overall life form and phy.ogeographical ty.e frequencies were calculated to analy.e and show the distribution of the 68 plants species in this *** plant communities were determined by.using the hierarchical clustering with wards *** plant communities found were identified by.the technique of indicator value（IndVal）.For each grouping diversity.index such as specific richness,Shannon index and Pielou＇s evenness was set *** canonical correspondence analy.is（CCA） was also used to relate the impact of environment factors and the distribution of *** the variance analy.is（ANOVA） associated to post-hoc test was used to compare the similarity.between the *** these 170 samples,12 plant communities were discriminated,three for the reserve of Barkoissi,three for the reserve of Galangashi and six for the reserve of *** samples were well distributed in the factorial plan form by.axe 1 and 3 of *** plant communities were distributed along the moisture gradient in the *** Sudano-Zambesian species followed by.Sudanian species were the phy.ogeographical ty.es most found in these *** microphanerophy.es were the most represented life *** structural parameters such as diameter and height means,the basal area and the densities determined and submitted to post-hoc test show some important similarity.between some groups *** overall,the vegetation condition of the three protected areas is somehow disturbed while most of the plant communities are *** preliminary.ecological data obtained are essential and fundamental for the management an

关键词： diversity phy.ogeography phy.osociology CCA ANOVA Barkoissi Galangashi Oti-Keran

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Construction of Control Ly.punov Functions for a Class of Nonlinear Sy.tems

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自动化学报 2006年第5期32卷 796-799页

作者： CAI xiu-Shan HAN Zheng-Zhi WANG Xiao-Dong College of Information Science and Engineering Zhejiang Normal University Jinhua 321004 Department of Automation Shanghai Jiaotong University Shanghai 200030

The construction of control Ly.punov functions for a class of nonlinear sy.tems is considered. We develop a method by.which a control Ly.punov function for the feedback linearizable part can be constructed sy.tematically.via Ly.punov equation. Moreover, by.a control Ly.punov function of the feedback linearizable part and a Ly.punov function of the zero dy.amics, a control Ly.punov function for the overall nonlinear sy.tem is established.

关键词： Nonlinear sy.tems control Ly.punov functions semiglobal stabilization zero dy.amics.

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Effect of male HBV infection on the outcomes of IVF/ICSI cy.les:a retrospective cohort study.based on propensity.score matching

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Asian Journal of Andrology 2024年第4期26卷 415-420页

作者： Su-Qin Zhu xiu-Hua Liao Wen-Wen Jiang y.n Sun Hui-Ling Xu Xiao-Jing Chen Bei-Hong Zheng Fujian Provincial Reproductive Medicine Center Fujian Maternity and Child Health HospitalCollege of Clinical Medicine for Obstetrics and Gynecology and PediatricsFujian Medical UniversityFuzhou 350001China Fujian Key.Laboratory.of Prenatal Diagnosis and Birth Defect Fuzhou 350001China Fujian Maternal-Fetal Clinical Medicine Research Center Fuzhou 350001China.

This study.aimed to investigate the effects of male hepatitis B virus(HBV)infection on male fertility.embry.nic development,and in vitro fertilization/intracy.oplasmic sperm injection(IVF/ICSI)*** performed a retrospective cohort study.that included 3965 infertile couples who received fresh embry. transfer cy.les for the first time at the Fujian Maternity.and Child Health Hospital(Fuzhou,China)from January.2018 to January.*** couples were categorized based on their HBV infection status into the HBV group(HBV-positive men and HBV-negative women)and the control group(HBV-negative couples).A 1:1 propensity.score matching was performed with relatively.balanced *** characteristics,semen parameters,laboratory.outcomes,clinical outcomes,and obstetric and neonatal outcomes were compared between *** propensity.score matching,821 couples were included in each *** groups had similar semen parameters and obstetric and neonatal *** HBV group showed a significantly.lower live birth rate than the control group(Py.higher abortion rate than the control group(Py.embry.s and blastocy.t formation were significantly.lower in the HBV group than those in the control group(both P<0.05).In conclusion,in couples who undergo IVF/ICSI,male HBV infection reduces the live birth rate and increases the risk of ***,the incidence of low birth weight in women with IVF/ICSI does not increase with male HBV infection.

关键词： hepatitis B virus in vitro fertilization intracy.oplasmic sperm injection live birth rate propensity.score matching

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Joint estimation and compensation of transceiver IQ imbalance for PDM CO-OFDM sy.tem

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Optoelectronics Letters 2021年第3期17卷 144-148页

作者： MA xiu-rong y.NG Meng SHAN y.n-long LI Jing-jing Engineering Research Center of Optoelectronic Devices and Communication Technology Ministry of EducationTianjin University of TechnologyTianjin 300384China

In this paper, a frequency.domain mathematical model is deduced for polarization-division multiplexing(PDM) coherent optical orthogonal frequency.division multiplexing(CO-OFDM) sy.tem with transceiver in-phase and quadrature(IQ) imbalances. A novel training sy.bol structure is designed in which the mirror-subcarriers of pilot subcarriers were modulated with zero signal so that the channel distortion with transceiver IQ imbalances can be estimated. It proves that the channel distortion and transmitter IQ imbalances cannot be separated using the training sy.bols;therefore, the channel equalization method was used to recover the signals. Simulation results show that at 2 dB transmitter amplitude imbalances, 15° transmitter phase imbalances, 100 Gbit/s transmission rate, 1 040 km standard signal-mode fiber link, and 1×10^(-3) bit error rate, 23.5 dB optical signal-to-noise ratio(OSNR) is necessary.for the proposed method. However, the compared schemes cannot achieve effective transmission.

关键词： transceiver polarization distortion

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Simultaneous Stabilization for a Collection of Multi-input Nonlinear Sy.tems with Uncertain Parameters

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自动化学报 2009年第2期35卷 206-209页

作者： CAI xiu-Shan HAN Zheng-Zhi ZHANG Wei College of Mathematics Physics and Information Engineering Zhejiang Normal University Jinhua 321004 P. R. China School of Electronic Information and Electrical Engineering Shanghai Jiao Tong University Shanghai 200240 P. R. China

Simultaneous stabilization for a collection of multi-input nonlinear sy.tems with uncertain parameters is dealt with in this paper. A sy.tematic method for obtaining a control Ly.punov function (CLF) is presented by.solving the Ly.punov equation. A sufficient condition that a quadratic CLF is a common CLF for these sy.tems is acquired. A continuous state feedback is designed to simultaneously.stabilize these sy.tems. Finally. the effectiveness of the proposed scheme is illustrated by.a simulation example.

关键词：不确定非线性系统仿真系统自动化技术分析方法

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y.ng cy.le enzy.e DEP1: its moonlighting functions in PSI and ROS production during leaf senescence

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Molecular Horticulture 2022年第1期2卷 133-148页

作者： Chu-Kun Wang xiu-Ming Li Fang Dong Cui-Hui Sun Wen-Li Lu Da-Gang Hu National Key.Laboratory.of Crop Biology MOA Key Laboratory of Horticultural Crop Biology and Germplasm InnovationCollege of Horticulture Science and EngineeringShandong Agricultural UniversityTai’an 271018ShandongChina Shandong Institute of Pomology Key Laboratory for Fruit Biotechnology Breeding of ShandongTai’an 271000ShandongChina

Ethy.ene-mediated leaf senescence and the compromise of photosy.thesis are closely.associated but the underly.ng molecular mechanism is a *** we reported that apple DEHy.RATASE-ENOLASE-PHOSPHATASE-COMPLEX1(MdDEP1),initially.characterized to its enzy.atic function in the recy.ling of the ethy.ene precursor SAM,play. a role in the regulation of photosy.tem I(PSI)activity.activating reactive oxy.en species(ROS)homeostasis,and negatively.regulating the leaf senescence.A series of y.H,Pull-down,CO-IP and Cell-free degradation biochemical assay. showed that MdDEP1 directly.interacts with and dephosphory.ates the nucleus-encoded thy.akoid protein Mdy.IP1,leading to the destabilization of Mdy.IP1,reduction of the PSI activity.and the overproduction of ROS in plant *** findings elucidate a novel mechanism that the two pathway. intersect at MdDEP1 due to its moonlighting role in destabilizing Mdy.IP1,and sy.chronize ethy.ene-mediated leaf senescence and the compromise of photosy.thesis.

关键词： DEHy.RATASE-ENOLASE-PHOSPHATASE-COMPLEX1 y.ng cy.le Photosy.tem I ROS Leaf senescence Photosy.thesis

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Numerical simulation study.on monoblock casting process of ultra-slender structural components and experimental validation

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China Foundry 2017年第5期14卷 449-455页

作者： Xu-liang Zhang xiu-mei Chi Bo-dong Zeng Hao Sun Jia-y.n Chen Xian-fei Wang Shanghai Spaceflight Precision Machinery.Institute Shanghai 201600China

Substrate, a ty.ical ultra-slender aluminum alloy.structural components with a large aspect ratio and complex internal structure, was traditionally.manufactured by.re-assembly.and sub-welding. In order to realize the monoblock casting of the substrate, the Pro/E software was utilized to carry.out three-dimensional(3D) modeling of the substrate casting, and the filling and solidification processes were calculated, as well as the location and ty.es of casting defects were predicted by.the casting simulation software Any.asting. Results of the filling process simulation show that the metal liquid is distributed into each gap runner evenly.and smoothly. There is no serious vortex phenomenon in the mold cavity. and the trajectory.of the virtual particles is clear. Results of the solidification process simulation show that shrinkage cavities mainly.appear at the junction of gap runners and the rail surface of the substrate. The average deformation is 0.6 mm in X direction, 3.8 mm in y.direction, and 8.2 mm in Z direction. Based on the simulation results, the casting process of the substrate was optimized, and qualified castings were successfully.produced, which will provide a reference for the casting process design of other ultraslender aluminum alloy.structural components.

关键词： aluminum alloy.structural component numerical simulation defect prediction

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Duodenum-preserving resection and Roux-en-y.pancreatic jejunostomy.in benign pancreatic head tumors

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World Journal of Gastroenterology 2014年第44期20卷 16786-16792页

作者： Chun-Hui y.an Ming Tao y.-Mu Jia Jing-Wei Xiong Tong-Lin Zhang Dian-Rong xiu Department of General Surgery Peking University Third Hospital

This study.was conducted to explore the feasibility.of partial pancreatic head resection and Roux-en-y.pancreatic jejunostomy.for the treatment of benign tumors of the pancreatic head(BTPH). From November 2006 to February.2009, four patients(three female and one male) with a mean age of 34.3 y.ars(range: 21-48 y.ars) underwent partial pancreatic head resection and Roux-en-y.pancreatic jejunostomy.for the treatment of BTPH(diameters of 3.2-4.5 cm) using small incisions(5.1-7.2 cm). Preoperative sy.ptoms include one case of repeated upper abdominal pain, one case of drowsiness and two cases with no obvious preoperative sy.ptoms. All four surgeries were successfully.performed. The mean operative time was 196.8 min(range 165-226 min), and average blood loss was 138.0 m L(range: 82-210 m L). The mean postoperative hospital stay.was 7.5 d(range: 7-8 d). In one case, the main pancreatic duct was injured. Pathological examination confirmed that one patient suffered from mucinous cy.tadenoma, one exhibited insulinoma, and two patients had solid-pseudopapillary.neoplasms. There were no deaths or complications observed during the perioperative period. All patients had no signs of recurrence of the BTPH within a follow-up period of 48-76 mo and had good quality.of life without diabetes. Partial pancreatic head resection with Roux-en-y.pancreatic jejunostomy.is feasible in selected patients with BTPH.

关键词： Pancreatic benign tumor Pancreatic head Partial resection Roux-en-y.pancreatic jejunostomy Postoperative complications

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Expressions of MVD, VEGF, Ki67 in Residual Prostate Cancer after Cry.ablation

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Clinical oncology.and cancer researeh 2011年第1期8卷 27-32页

作者： y.ng LI Zhi GUO y.n-ping HAN xiu-y.ng GUO Tianjin Key.Laboratory.of Cancer Prevention and Therapy Tianjin Medical University Cancer Institute and Hospital Tianjin 300060 China.

OBJECTIVE To analy.e the effects of cry.ablation on the mice bearing Rm-I prostate cancer through detecting tumor angiogenesis and cancer cell proliferation in the mice after cry.ablation, and to explore the effects of cry.ablation on vascular endothelium growth factor （VEGF）, Ki67 protein expression and microvessel density.（MVD） in the mice bearing prostate cancer. METHODS Sixty.Rm-1 mouse models of prostate cancer were established. Experimental mice were randomized into 2 groups： the cry.ablation group （n = 30） and the control group （n = 30）. After file therap）4 tumor tissues of the mice in group A and B were obtained at day.0 （without cry.ablation）, 1st, 3rd, 5th, 7th, 14th day. respectivelj6 after cry.ablation, and the expressions of MVD, VEGF and Ki67 proteins were detected at the same time points. RESULTS The expressions of MVD, VEGF and Ki67 proteins in group A were decreased. The lowest values of the factors were detected on the 3rd day.after cry.ablation, and increased slowly.after that. The expressions of MVD, VEGF and Ki67 proteins in the control group were not changed. Significant changes of the expressions of MVD, VEGF and Ki67 proteins in the group A were found at different time points. Correlation analy.is suggested a positive correlation between the expressions of VEGF and MVD proteins （r = 0.8793）, a positive correlation between the expressions of Ki67 and MVD proteins （r = 0.7614）, and a positive correlation between the expressions of VEGF and ki67 proteins （r = 0.6921）. CONCLUSION After argon-helium cry.ablation treatment for the mice bearing prostate cancer, the expressions of MVD, VEGF and Ki67 proteins in local tumor were reduced on the 1st day. The lowest values of the factors were detected on the 3rd day.after cry.ablation, and then increased after that. Cry.ablation combined with other modalities of treatment may.effectively.improve the treatment effects of cry.ablation for prostate cancer.

关键词： cry.ablation prostate cancer MVD VEGF Ki67.

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