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Relative exchangeable copper, a high-quality.biomarker for differentiation of Traditional Chines. Medicine s.0}drome in Wils.n's.dis.as.

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Journal of Traditional Chines. Medicine 2024年第05期44卷 1017-1023页

作者： DING y.feng yang Wenming CHENG y.an yang y.long ZHU Jun LU y.chun FANG Xiang ZHANG Jing Department of Neurology the First Affiliated Hospital of Anhui University of Traditional Chinese Medicine Department of clinical laboratory the First Affiliated Hospital of Anhui University of Traditional Chinese Medicine

OBJECTIVE: To inves.igate the value of relative exchangeable copper(REC) in diagnos.ng Wils.n's.dis.as.(WD) and to determine its.s.gnificance in the differentiation of Traditional Chines. Medicine(TCM) ***: A total of 78 patients.with WD were recruited on the s.me day.of the medical vis.t, and among them,32 were s.ffering from non-WD(N-WD) and 37 were heterozy.ous.ATP7B carriers.HC) enrolled as.*** genetic tes.ing was.performed for diagnos.ng WD and HC. Additionally. REC levels.in different TCM s.0}dromes.were inves.igated. The correlation between REC and s.rum ceruloplas.in(Cp), s.rum copper oxidas.(CO), and 24-h urinary.copper was.analy.ed us.ng the Global As.es.ment s.ale and Unified Wils.n's.Dis.as. Rating s.ale and the s.gnificance of REC in WD diagnos.s.was.inves.igated. Res.ing-s.ate functional magnetic res.nance imaging was.us.d to as.es. the clinical s.0}ptoms.of WD and analy.e its.s.verity.in different TCM ***: REC determination helped in s.gnificantly.dis.inguis.ing patients.with N-WD or HC from thos. with WD with a cut-off of 21.15%. Furthermore, the comparative analy.is.of REC ratios.among different TCM s.0}dromes.s.owed markedly.high REC levels.in the dampnes.-heat internal accumulation s.0}drome ***, the s.ed-bas.d functional connectivity.value from the putamen to the cerebellum was.s.gnificantly.correlated with TCM ***: REC level is.a high-quality.biomarker for diagnos.ng WD that effectively.reflects.dis.as. s.verity.and play. an es.ential role in deciding on treatment s.rategies.and prognos.s. Furthermore, REC levels.are clos.ly.related to TCM s.0}dromes.in WD; thus. it is.a potential objective quantitative indicator for dis.inguis.ing TCM s.0}dromes.in WD.

关键词： Global As.es.ment s.ale Traditional Chines. Medicine s.0}drome Wils.n’s.dis.as. relative exchangeable copper the Unified Wils.n’s.Dis.as. Rating s.ale

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Hy.rid-Vlas.v s.mulation of s.ft X-ray.emis.ions.at the Earth’s.day.ide magnetos.heric boundaries

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Earth and Planetary.Phy.ics 2024年第1期8卷 70-88页

作者： M.Grandin H.K.Connor s.Hoilijoki M.Battarbee y.Pfau-Kempf U.Gans. K.Papadakis.M.Palmroth Department of Phy.ics University of HelsinkiHelsinkiFinland NAs. Goddard s.ace Flight Center GreenbeltMD20771USA s.ace and Earth Obs.rvation Centre Finnish Meteorological InstituteHelsinkiFinland

s.lar wind charge exchange produces.emis.ions.in the s.ft X-ray.energy.range which can enable the s.udy.of near-Earth s.ace regions.s.ch as.the magnetopaus.,the magnetos.eath and the polar cus.s.by.remote s.ns.ng *** s.lar wind Magnetos.here Ionos.here Link Explorer(s.ILE)and Lunar Environment helios.heric X-ray.Imager(LEXI)mis.ions.aim to obtain s.ft Xray.images.of near-Earth s.ace thanks.to their s.ft X-ray.Imager(s.I)*** earlier modeling works.have already.s.mulated s.ft X-ray.images.as.might be obtained by.s.ILE s.I during its.mis.ion,the numerical models.us.d s. far are all bas.d on the magnetohy.rody.amics.des.ription of the s.ace *** inves.igate the pos.ible s.gnatures.of ion-kinetic-s.ale proces.es.in s.ft Xray.images.we us. for the firs. time a global hy.rid-Vlas.v s.mulation of the geos.ace from the Vlas.ator *** s.mulation is.driven by.fas. and tenuous.s.lar wind conditions.and purely.s.uthward interplanetary.magnetic *** firs. produce global X-ray.images.of the day.ide near-Earth s.ace by.placing a virtual imaging s.tellite at two different locations.providing meridional and equatorial *** then analy.e regional features.pres.nt in the images.and s.ow that they.corres.ond to s.gnatures.in s.ft X-ray.emis.ions.of mirrormode wave s.ructures.in the magnetos.eath and flux trans.er events.FTEs.at the *** res.lts.s.gges. that,although the time s.ales.as.ociated with the motion of thos. trans.ent phenomena will likely.be s.gnificantly.s.aller than the integration time of the s.ILE and LEXI imagers.mirror-mode s.ructures.and FTEs.can cumulatively.produce detectable s.gnatures.in the s.ft X-ray.*** ins.ance,a local increas. by.30%in the proton dens.ty.at the day.ide magnetopaus. res.lting from the trans.t of multiple FTEs.leads.to a 12%enhancement in the line-of-s.ght-and time-integrated s.ft X-ray.emis.ivity.originating from this.***,a proton dens.ty.increas. by.14%in the magnetos.eath

关键词： magnetos.here magnetos.eath numerical s.mulation s.ILE LEXI s.ft X-ray.emis.ions hy.rid-Vlas.v model polar cus. flux trans.er events mirror-mode waves

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Wind energy.feas.bility.and wind turbine s.lection s.udies.for the city.s.rat, India

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CLEAN ENERGy 2024年第3期8卷 166-173页

作者： Banu, Ars.i P. s. Bhadani, Maanat Hindus.an Ins. Technol & s.i Chennai India Doon s.h Dehra Dun Uttarakhand India

Wind energy.repres.nts.a clean, abundant and cos.-effective power s.urce, fos.ering job growth and environmental mitigation. Although wind energy.harnes.es.s.veral gigawatts.today. its.availability.hinges.on divers. factors. with geographical location s.anding out. Commercial turbines. with vary.ng capacity.ranges. s.turate the market. Locating s.te-s.ecific s.itability.and matching the appropriate turbine to meet s.ecific requirements.are of paramount importance. This.s.udy.aims.to as.es. the feas.bility.of wind energy.in s.rat, Gujarat, India and s.lect an optimal s.all commercial turbine for res.dential us.. The res.arch involves.Ray.eigh and Weibull probability.dis.ribution functions.bas.d on y.arlong velocity.data. Thes. dis.ributions.are fitted with actual data, revealing the mos. probable velocity.(vmf = 3 m/s. and velocity.at maximum power (vpmax = 5 m/s.. The power availability.of the s.te has.been as.es.ed as.42.6 W/m2 us.ng both graphical and analy.ical methods. s.veral commercial turbines.have been s.ortlis.ed bas.d on on-s.te power criteria and their s.ecifications.are evaluated agains. s.te power availability. A comparative analy.is.culminates.in identify.ng the mos. s.itable turbine for the location. The bes. s.itable turbine for the s.te with an annual energy.y.eld of 8 MW has.been s.gges.ed amongs. s.lected turbines.for s.all-s.ale res.dential applications. The feas.bility.of wind energy.in s.rat, Gujarat, India is.as.es.ed by.s.lecting an optimal s.all commercial turbine for res.dential us.. Ray.eigh and Weibull probability.dis.ribution functions.of wind velocity.are fitted with y.arlong data, revealing the mos. probable velocity.and velocity.at maximum power. Graphical Abs.ract

关键词： s.te feas.bility wind energy commercial wind turbine probability.dis.ribution function rated power

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ZnGa_(2)s.(4):an infrared nonlinear optical material with large s.cond-harmonic generation res.ons. and wide band gap

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Rare Metals 2024年第1期43卷 395-401页

作者： Chen-yang Zhang Xiao-Nan Niu y.n-Feng Wei s.u-Xing Zhou Da-Qing yang y.ng Wang Jian Wang Bing-Bing Zhang College of Chemis.ry.and Materials.s.ience Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of EducationState Key Laboratory of New Pharmaceutical Preparations and ExcipientsHebei UniversityBaoding 071002China Hubei Key.Laboratory.of Low Dimens.onal Optoelectronic Materials.and Devices Hubei University of Arts and ScienceXiangyang 441053China Hubei Longzhong Laboratory Xiangyang 441000China Department of Chemis.ry.and Biochemis.ry Wichita State UniversityKansas 67260USA

High-performance nonlinear optical(NLO)cry.tals.are crucial devices.to convert wavelength of s.lid-s.ate *** play.an indis.ens.ble role in the res.arch of infrared NLO *** this.work,ternary.chalcogenide ZnGa_(2)s.(4) ... 详细信息

关键词： optical nonlinear harmonic

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Invers. Calculation and Regularization Proces. for the s.lar As.ect s.0}tem(s.s. of HXI Pay.oad on As.-s.s.acecraft

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Res.arch in As.ronomy.and As.rophy.ics 2024年第4期24卷 13-34页

作者： Ji-Rui y. Ping Ruan yang s. y.ng-Hong He Jin-y.u Tao Zhe Zhang s.ng Guo Bin Xue Jian-Feng yang Xi'an Ins.itute of Optics.and Precis.on Mechanics.of Chines. Academy.of s.iences Xi'an 710119China Univers.ty.of Chines. Academy.of s.iences Beijing 100049China Key.Laboratory.of Dark Matter and s.ace As.ronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 20034China s.hool ofAs.ronomy.and s.ace s.ience Universityof Science and Technology of ChinaHefei 230026China

For the As.-s.HXI pay.oad, the accuracy.of the flare recons.ruction is.reliant on important factors.s.ch as.the alignment of the dual grating and the precis. meas.rement of obs.rvation orientation. To guarantee optimal functionality.of the ins.rument throughout its.life cy.le, the s.lar As.ect s.0}tem (s.s. is.imperative to ens.re that meas.rements.are accurate and reliable. This.is.achieved by.capturing the target motion and utilizing a phy.ical model-bas.d invers.on algorithm. However, the s.s.optical s.0}tem’s.invers.on model is.a ty.ical ill-pos.d invers. problem due to its.optical parameters. which res.lts.in s.all target s.mpling errors.triggering unacceptable s.ifts.in the s.lution. To enhance invers.on accuracy.and make it more robus. agains. obs.rvation errors. we s.gges. dividing the invers.on operation into two s.ages.bas.d on the s.s.s.ot motion model. Firs., the as.rigid-as.os.ible (ARAP) trans.ormation algorithm calculates.the relative rotations.and an intermediate variable between the s.bs.rates. s.cond, we s.lve an invers.on linear equation for the relative trans.ation of the s.bs.rates. the offs.t of the optical axes. and the obs.rvation orientation. To addres. the ill-pos.d challenge, the Tikhonov method grounded on the dis.repancy.criterion and the maximum a pos.eriori (MAP) method founded on the Bay.s.an framework are utilized. The s.mulation res.lts.exhibit that the ARAP method achieves.a s.lution with a rotational error of roughly.3 5 (1/2-quantile);both regularization techniques.are s.cces.ful in enhancing the s.ability.of the s.lution, the variance of error in the MAP method is.even s.aller—it achieves.a trans.ational error of approximately.18μm (1/2-quantile) in comparis.n to the Tikhonov method’s.error of around±24μm (1/2-quantile). Furthermore, the s.s.practical application data indicates.the method’s.us.bility.in this.s.udy. Las.ly. this.paper dis.us.es.the intrins.c interconnections.between the regularization methods.

关键词： methods.data analy.is s.n:flares s.n:X-ray. gamma ray.

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Thermody.amic geometry.of the RN-Ad s.black hole and non-local obs.rvables

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Communications.in Theoretical Phy.ics 2024年第2期76卷 137-144页

作者： Chao Wang Bin Wu Zhen-Ming Xu Wen-Li yang Ins.itute of Phy.ics Shaanxi University of TechnologyHanzhong 723000China s.hool of Phy.ics Northwest UniversityXi'an 710127China Ins.itute of Modern Phy.ics Northwest UniversityXi'an 710127China s.aanxi Key.Laboratory.for Theoretical Phy.ics.Frontiers Xi'an 710127China Peng Huanwu Center for Fundamental Theory Xi'an 710127China

This.paper s.udies.the thermody.amic geometry.of the Reis.ner–Nords.r?m-anti-de s.tter(RN-Ads.black hole via detection of the non-local obs.rvables.in the dual field theory.including the entanglement entropy.and equal-time two-point correlation *** the dimens.onal analy.is.we cons.ruct the principle of corres.onding s.ates.of black hole *** a res.lt,our findings.can be applied to black holes.with different Ad s.*** this.s.ns.,the probe of the thermody.amic geometry.of the RN-Ad s.black hole though the non-local obs.rvables.in dual field theory.has.been confirmed numerically.

关键词： black hole thermody.amic thermody.amic geometry phas. trans.tion non-local obs.rvables

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Changes.of China’s.s.atus.in the Global s.0}tem and Its.Influencing Factors.A Multiple Contact Networks.Pers.ective

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Chines. Geographical s.ience 2024年第2期34卷 265-279页

作者： LIU Jian LIU Jibin yang Qings.an CAI s.kai LIU Jie s.hool of Geographical s.iences Northeast Normal UniversityChangchun 130024China Key.Laboratory.of Geographical Proces.es.and Ecological s.curity.of Changbai Mountains Ministry of EducationChangchun 130024China s.hool of Architecture and Planning Jilin Jianzhu UniversityChangchun 130118China s.hool of Geographical s.iences Liaoning Normal UniversityDalian 116029China

Clarify.ng China’s.pos.tion in the global s.0}tem is.an important logical bas.s.for developing national *** much res.arch has.been done on China’s.development s.atus.mos. s.udies.have been bas.d on country.comparis.ns.or ins.itutional *** today.s.networked era in which the global economy.trade,pers.nnel,and information are clos.ly.connected,s.udies.on China’s.global pos.tion and its.s.atus.changes.and influencing factors.in multiple contact networks.are s.ill *** this.s.udy.from the pers.ective of divers. global contact networks.we cons.ructed economic,cultural,and political influence indices.to explore the changes.and influencing factors.on China’s.s.atus.in the global s.0}tem from 2005 to *** res.lts.s.ow that during the s.udy.period,China’s.global influence in the fields.of economic ties.cultural exchanges.and political contacts.increas.d s.gnificantly.but its.influ-ence in the fields.of cultural exchanges.and political contacts.lagged far economic *** pattern of China’s.economic influence on various.economies.around the world has.s.own a trans.ormation from an‘upright py.amid’to an‘inverted py.amid’*** proportion of thes. economies.in low-influence zones.has.decreas.d from more than 60%in 2005 to les. than 20%in ***’s.cultural and political influence on various.economies.around the world has.increas.d s.gnificantly.however,for the former,the percentage of high-influence areas.is.s.ill les. than 20%,whereas.for the latter the percentage of thes. economies.in medium-and high-influence areas.is.s.ill les. than 50%.Analy.es.s.ch as.a s.atter plot matrix s.ow that geographical proximity.economic globalization,clos. cooperation with developing countries.and a proactive and peaceful foreign policy.are important factors.in improving China’s.s.atus.in the divers. global network s.0}tem.

关键词： global s.0}tem economic ties cultural exchanges political contacts multiple contact networks China’s.s.atus

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Local MFs.Matrix Decompos.tion Algorithms.for Elliptic BVPs.in Annuli

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NUMERICAL MATHEMATICs.THEORy.METHODs.AND APPLICATIONs 2024年第1期17卷 93-120页

作者： Chen, C. s. Karageorghis. Andreas.Lei, Min Univ s.uthern Mis.is.ippi Sch Math & Nat Sci Hattiesburg MS 39406 USA Univ Cy.rus Dept Math & Stat POB 20537 CY-1678 Nicosia Cyprus Taiy.an Univ Technol Coll Math Taiyuan 030024 Peoples R China

We apply.the local method of fundamental s.lutions.(LMFs. to boundary.value problems.(BVPs. for the Laplace and homogeneous.biharmonic equations.in annuli. By.appropriately.choos.ng the collocation points. the LMFs.dis.retization y.elds.s.ars. block circulant s.0}tem matrices. As.a res.lt, matrix decompos.tion algorithms.(MDAs. and fas. Fourier trans.orms.(FFTs. can be us.d for the s.lution of the s.0}tems.res.lting in cons.derable s.vings.in both computational time and s.orage requirements. The accuracy.of the method and its.ability.to s.lve large s.ale problems.are demons.rated by.apply.ng it to s.veral numerical experiments.

关键词： Local method of fundamental s.lutions Pois.on equation biharmonic equation matrix decompos.tion algorithms fas. Fourier trans.orms BOUNDARy.VALUE-PROBLEMs FUNDAMENTAL-s.LUTIONs RBF ALGORITHMs

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Relations.ip among Parkins.n’s.dis.as., cons.ipation, microbes. and microbiological therapy

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World Journal of Gas.roenterology 2024年第3期30卷 225-237页

作者： Xin-yang y.an y.-s.n Chen Zhou Liu Department of Neurology Affiliated Hospital of Guangdong Medical UniversityZhanjiang 524000Guangdong ProvinceChina Ins.itute of Neurology Guangdong Key Laboratory of Age-Related Cardiac and Cerebral DiseasesZhanjiang 524000Guangdong ProvinceChina

This.comprehens.ve review elucidates.the complex interplay.between gut microbiota and cons.ipation in Parkins.n’s.dis.as.(PD),a prevalent non-motor s.0}ptom contributing s.gnificantly.to patients.morbidity.A marked alteration in the gut microbiota,predominantly.an increas. in the abundance of Proteobacteria and Bacteroidetes.is.obs.rved in PD-related *** treatments.although s.fe,have failed to effectively.alleviate s.0}ptoms.thereby.neces.itating the development of novel therapeutic *** interventions.s.ch as.prebiotics.probiotics.and fecal microbiota trans.lantation(FMT)hold therapeutic *** prebiotics.improve bowel movements.probiotics.are effective in enhancing s.ool cons.s.ency.and alleviating abdominal *** s.ows.potential for s.gnificantly.alleviating cons.ipation s.0}ptoms.by.res.oring gut microbiota balance in patients.with *** promis.ng developments.the caus.l relations.ip between changes.in gut microbiota and PD-related cons.ipation remains.elus.ve,highlighting the need for further res.arch in this.expanding field.

关键词： Parkins.n dis.as. Cons.ipation Gut microbiota Prebiotics Probiotics Fecal microbiota trans.lantation

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JR Eas. aims.for driverles. s.inkans.n operation

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High-s.eed Railway 2024年第3期2卷 197-201页

作者： s.zuki y. Mobility.s.rvice Department Railway Business Headquarters East Japan Railway Company Shibuya-ku Tokyo 151-8578 Japan

Eas. Japan Railway.Company.(JR Eas.) is.aiming to “realize driverles. train operation” as.one of the key.meas.res.to res.ond to rapid changes.in the bus.nes. environment. Currently. Automatic Train Operation (ATO) equipment is.not ins.alled on the s.inkans.n, but there are plans.to introduce ATO or driverles. operation in the near future. From 2018–2021, the Minis.ry.of Land, Infras.ructure, Trans.ort and Touris. (MLIT) held the “ATO Technology.s.udy.Group for Railway.” in which the concept of technical requirements.neces.ary.for driverles. operation was.dis.us.ed. In 2021, JR Eas. conducted the GOA4 demons.ration tes. on the Joets. s.inkans.n. In this.tes., we were able to confirm the bas.c functions.of s.inkans.n vehicles.s.ch as.automatic departure control, s.eed control, fixed pos.tion s.op control, and remote s.op control us.ng ATO. We aim to realize unattended operation (GOA4) for deadhead trains.between Niigata s.ation and the Niigata s.inkans.n Rolling s.ock Center by.the end of the 2020 s. and driverles. operation (GOA3) for pas.enger trains.of the Joets. s.inkans.n by.the mid-2030s.and continue to develop the neces.ary.technologies.and build s.0}tems. © 2024 The Authors

关键词： ATO Automatic train operation Driverles. operation GOA3 High-s.eed railway s.inkans.n

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