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Prostate Tumors Diagnosis: Place of Fine Needle Aspiration in Congolese Patients

Open Journal of Pathology 2020年第1期10卷 1-15页

作者： C. F. S. Ngatali S. E. Okouango A. F. Bolenga Liboko L. M. A. Boumba E. Ndounga y. mabila D. Moukassa J. B. Nkoua-Mbon Department of Oncology.and Internal Medicine Loandjili General Hospital Pointe Noire Congo Medical Oncology.Department CHU-Brazzaville Brazzaville Congo Laboratory.of Anatomy.Pathology Loandjili General Hospital Pointe Noire Congo Hospital General Edith Lucie Bongo Oyo Congo

Objective: To determine the kappa (κ) concordance coefficient between fine needle aspiration and serum prostatic antigen (PSA) coupled with digital rectal examination and prostatic ultrasound. Material and Methods: We conducted a cross-sectional study.covering the period from January.1st to June 30th, 2018 in the city.of Pointe-Noire. It is a study.of 31 cases of prostate tumors in Congolese subjects at the General Hospital of Loandjili in Pointe-Noire of Congo Brazzaville. The clinical, biological, ultrasound and cy.ological aspects were the variables of the study. Results: The mean age was 71.06 y.ars with extremes of 57 and 93 y.ars. One patient had a family.history.of prostate cancer that was found at his brother’s house at the age of 52. Dy.uria was the most represented sign in all of our patients. Suspicion of prostate cancer was the most commonly.talked in digital rectal examination. Prostate specific antigen (PSA) was greater than or equal to 10 ng/ml in more 74% of our patients. 61.3% of our patients had a heterogeneous prostatic ultrasound. 48.3% of malignant tumors and 32.3% of benign tumors were found cy.ologically. The association between digital rectal examination and prostatic ultrasound was statistically.significant (p ≤ 0.05) and good agreement was found between cy.ological diagnosis coupled with digital rectal examination and prostatic echostructure (0.6 ≤ κ ≤ 0.8). A low concordance between prostatic specific antigen (PSA) and cy.ological concordance was noted (0.2 ≤ κ ≤ 0.4). Conclusion: Prostatic tumors in Congo in their diagnostic particularities are dominated by.malignant tumors with a large number of patients to watch. The fine needle aspiration is suitable for orientation examinations of prostatic tumors and can be performed by.any.doctor and provides us a fast, effective diagnostic orientation with a strong clinico-morphological correlation in our low incomes countries.

关键词： Fine Needle Aspiration Prostate Tumors Diagnosis Congolese

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Breast Cancer: Epidemiological, Clinical, and Therapeutic Aspects in Pointe Noire (Congo Brazzaville)

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Open Journal of Pathology 2019年第4期9卷 76-85页

作者： C. F. S. Ngatali A. F. Bolenga Liboko E. Ndounga y. mabila D. Moukassa J. B. Nkoua-Mbon P. E. G. Sounga Bandzouzi L. M. A. Boumba Department of Oncology.and Internal Medicine Loandjili General Hospital Pointe Noire Congo Medical Oncology.Department CHU-Brazzaville Brazzaville Congo Hospital General Edith Lucie Bongo Oyo Congo Departement of Neurology Loandjili General Hospital Pointe Noire Congo Laboratoire d’Anatomie Pathologie Loandjili General Hospital Pointe Noire Congo

Introduction: Breast cancer is the leading cancer and the leading cause of cancer death in women worldwide. The objective of our study.was to describe the epidemiological, clinical and therapeutic aspects of breast cancer at the General Hospital of Loandjili in Pointe Noire. Patients and Methods: This was a descriptive and cross-sectional study.that took place in the Cancer Department of the General Hospital of Loandjili in Pointe Noire during the period from January.1st, 2012 to December 31st, 2016 for duration of 5 y.ars. 54 records of patients over 18 y.ars of age with histological evidence were collected. The variables studied were: age, level of education, time to presentation, telltale sign, stage of extension, histological ty.e, and histological grade. Chi-square test was used to compare variables and groups. Results: At the end of this study. we collected 54 files of breast cancer patients from 150 patients hospitalized in the Cancer Department. The frequency.of breast cancer was 36%. The average age was 50 ± 13.6 y.ars;the extremes were 27 y.ars and 79 y.ars. The most represented age group was from 37 to 40 y.ars old with a percentage of 28%. The patient’s level of study.was primary.in the majority.of cases (57%). The most represented histological ty.e was invasive ductal carcinoma, (100%). The majority.of patients arrived at advanced stages 44.4% and metastatic stages 26%. Patients were treated in most of cases by.chemotherapy.(82%), surgery.(42%) and radiotherapy.(10%). There was a correlation between time of presentation and stage of extension. Conclusion: Breast cancer is the first cancer of the woman in Pointe Noire. Patients arrive at advanced stages;the most common histological ty.e is invasive ductal carcinoma. The presentation time is correlated with the extension stage. These results suggest the establishment of a cancer control program in developing countries.

关键词： Epidemiological Clinical Therapeutic Breast Cancer Pointe Noire

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Metastatic Breast Cancer Survival in Pointe Noire: Analy.is of 30 Cases

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Open Journal of Pathology 2019年第4期9卷 86-99页

作者： C. F. S. Ngatali A. F. Bolenga Liboko M. L. Eouani L. M. A. Boumba P. E. G. Sounga Bandzouzi E. Ndounga y. mabila D. Moukassa J. B. Nkoua-Mbon Department of Oncology.and Internal Medicine Loandjili General Hospital Pointe Noire Congo Medical Oncology.Department CHU-Brazzaville Brazzaville Congo Department of Gy.ecology Loandjili General Hospital Pointe Noire Congo Laboratoire d’Anatomie Pathologie Loandjili General Hospital Pointe Noire Congo Departement of Neurology Loandjili General Hospital Pointe Noire Congo Hospital General Edith Lucie Bongo Oyo Congo

Introduction: Breast cancer is the leading cancer and the leading cause of cancer death in women worldwide. About 5% to 10% of breast cancer patients present with metastases. While the 5-y.ar survival of patients with local breast cancer varies around 98.8%, this survival rate drops to around 26.3% for metastatic patients. The objective of this study.was to determine the survival of patients with metastatic breast cancer in resource-limited settings. Patients and Methods: This was a cross-sectional descriptive study.that took place in the Cancer Department of the General Hospital of Loandjili in Pointe Noire during the period from January.1, 2013 to December 31, 2018, for duration of 6 y.ars. 30 records of patients over 18 y.ars of age and with histological evidence who received at least 3 courses of chemotherapy.were collected. The variables studied were: age, level of education, socio-economic level, menopausal status, history. WHO status, menopausal status, tumor size, histological ty.e, tumor location, the ty.e of treatment and survival. Survival was calculated by.Kaplan Meier method. Fisher’s exact test was used to search for correlation between variables. Results: The average age was 52.62 ± 10.96 y.ars old. The extremes were 33 y.ars and 75 y.ars old. The most represented level of education was the primary.level in 67% of cases. The majority.of patients had low socioeconomic status in 50% of cases. The patients were menopausal in 57% of cases. The antecedents of cancer were present in 13% of cases. 50% of patients had a WHO status performance at 2. The tumor size was greater than 2 cm in 77% of cases. The most represented histological ty.e was invasive ductal carcinoma in 93% of cases. The most represented histological grade was Scharff grade III Richardson bloom in 80% of cases. The most represented metastatic localization was pulmonary.in 33% of cases. The metastatic localizations were unique in 47% of cases and multiple in 53% of cases. Anthracy.line-based

关键词： Breast Cancer Metastatic Survival Pointe Noire Congo

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