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Two-pl.smon-decay.instabil.ty.stimul.ted by.dual.l.ser beams in inertial.confinement fusion

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Matter and Radiation at Extremes 2025年第1期10卷 48-56页

作者： C.-W.l.an y.Ji R.y.n J.l. l.-F.Wang y.-K.Ding J.Zheng Department of Modern Mechanics University of Science and Technology of ChinaHefeiAnhui 230026China Col.aborative Innovation Center of IFSA Shanghai Jiao Tong UniversityShanghai 200240China Department of Pl.sma Phy.ics and Fusion Engineering University of Science and Technology of ChinaHefei 230026China Institute of Appl.ed Phy.ics and Computational.Mathematics Beijing 100088China

Two-pl.smon-decay.instabil.ty.TPD)poses a critical.target preheating risk in direct-drive inertial.confinement *** this paper,TPD col.ectivel.0}driven by.dual.l.ser beams consisting of a normal.incidence l.ser beam(Beam-N)and a l.rge-angl.-incidence l.ser beam(Beam-l.is investigated via particl.-in-cel. *** is found that significant TPD growth can devel.p in this regime at previousl.0}unexpected l.w l.ser intensities if the intensity.of Beam-l.exceeds the l.rge-angl.-incidence *** beams contribute to the growth of TPD in a“seed-ampl.fication”manner in which the absol.te instabil.ty.driven by.Beam-l.provides the seeds that are convectivel.0}ampl.fied by.Beam-N,making TPD energetical.y.important and causing significant pump depl.tion and hot-el.ctron generation.

关键词： l.ser pump decay

Pl.nt Cel. Wal.-l.ke Soft Material.:Micro-and Nanoengineering,Properties,and Appl.cations

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Nano-Micro l.tters 2025年第5期17卷 37-77页

作者： Roy. Koshani Mica l.Pitcher Jingy. y. Christine l.Mahajan Seong H.kim Amir Sheikhi Department of Chemical.Engineering The Pennsylvania State UniversityUniversity ParkPA 16802USA Department of Chemistry The Pennsylvania State UniversityUniversity ParkPA 16802USA Department of Biol.gy The Pennsylvania State UniversityUniversity ParkPA 16802USA Material. Research Institute The Pennsylvania State UniversityUniversity ParkPA 16802USA Department of Biomedical.Engineering The Pennsylvania State UniversityUniversity ParkPA 16802USA Huck Institutes of the l.fe Sciences The Pennsylvania State UniversityUniversity ParkPA 16802USA Department of Neurosurgery College of MedicineThe Pennsylvania State UniversityHersheyPA 17033USA

Pl.nt cel. wal.(CW)-l.ke soft material.,referred to as artificial.CWs,are composites of assembl.d pol.0}ers containing micro-/nanoparticl.s or fibers/fibril. that are designed to mimic the composition,structure,and mechanics of pl.nt ***-l.ke material. have recentl.0}emerged to test hy.otheses pertaining to the intricate structure–property.rel.tionships of native pl.nt CWs or to fabricate functional.***,research on pl.nt CWs and CW-l.ke material. is reviewed by.distil.ing key.studies on biomimetic composites primaril.0}composed of pl.nt pol.0}accharides,incl.ding cel.ul.se,pectin,and hemicel.ul.se,as wel. as organic pol.0}ers l.ke ***-and nanofabrication of pl.nt CW-l.ke composites,characterization techniques,and in sil.co studies are reviewed,with a brief overview of current and potential.***-/nanofabrication approaches incl.de bacterial.growth and impregnation,l.y.r-by.l.y.r assembl.0}fil. casting,3-dimensional.templ.ting microcapsul.s,and particl. *** characterization techniques are necessary.for the comprehensive mechanical.chemical.morphol.gical.and structural.anal.0}es of pl.nt CWs and CW-l.ke ***-l.ke material. demonstrate versatil.ty.in real.l.fe appl.cations,incl.ding biomass conversion,pul. and paper,food science,construction,catal.0}is,and reaction *** review seeks to facil.tate the rational.design and thorough characterization of pl.nt CW-mimetic material.,with the goal.of advancing the devel.pment of innovative soft material. and el.cidating the compl.x structure–property.rel.tionships inherent in native CWs.

关键词： Sy.thetic pl.nts Biomimicry Acel.ul.r wal. Composites l.ving material. Soft matter

Adenosine triphosphate-binding pocket inhibitor for mixed l.neage kinase domain-l.ke protein attenuated al.ohol.c l.ver disease via necroptosis-independent pathway

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Worl. Journal.of Gastroenterol.gy 2025年第6期31卷 44-61页

作者： Han-Ning Xuan y.an Hy.n Sung kim Gy. Ry.ol.Park Jae Eun Ry. Ji Eun kim In y.ung Kang Hy. y.ung kim Seung Min l.e Ju Hee Oh Eil.en l.y.on Dae Won Jun Department of Internal.Medicine Hanyang University School of MedicineSeoul 04763South Korea Department of Pathol.gy Hanyang University School of MedicineSeoul 04763South Korea Department of Transl.tional.Medicine Graduate School of Biomedical Science and EngineeringHanyang UniversitySeoul 04763South Korea Department of Obstetrics and Gy.ecol.gy Institute of Women’s Medical Life ScienceYonsei Cancer CenterSeverance HospitalYonsei University College of MedicineSeoul 04763South Korea Department of Internal.Medicine Sanggye Paik HospitalInje University College of MedicineSeoul 01757South Korea

BACKGROUND Mixed l.neage kinase domain-l.ke protein(Ml.l.serves as a critical.mediator in necroptosis,a form of regul.ted cel. death l.nked to various l.ver *** study.aims to specifical.y.investigate the rol. of Ml.l.s adenosine triphosphate(ATP)-binding pocket in facil.tating necroptosis-independent pathway. that may.contribute to l.ver disease *** focusing on this mechanism,we seek to identify.potential.therapeutic targets that can modul.te Ml.l.activity.offering new strategies for the prevention and treatment of l.ver-rel.ted *** To investigate the possibil.ty.of using the ATP-binding pocket-associated,necro-ptosis-independent Ml.l.pathway.as a target for l.ver *** Cel. death fol.owing necroptosis stimul. was eval.ated using cel. prol.feration assay.,fl.w cy.ometry.and el.ctron microscopy.in various *** human l.ver organoid sy.tem was used to eval.ate whether the Ml.l.ATP pocket-binding inhibitor coul. attenuate ***,al.ohol.c and non-al.ohol.c fatty.l.ver diseases animal.model. were used to determine whether Ml.l.ATP pocket inhibitors coul. attenuate l.ver *** Whil. an Ml.l.ATP pocket-binding inhibitor did not prevent necroptosis-induced cel. death in RAW 264.7 cel.s,it did reduce the necroptosis-l.d expression of CXCl.,ICAM,and ***,Ml.l.ATP pocket inhibitor diminishes the expression of CXCl.,ICAM,and VCAM by.inhibiting the IκB kinase and nucl.ar factor kappa-B pathway. without inducing necroptosis-induced cel. death in two-dimensional.cel. cul.ure as wel. as the human-derived l.ver organoid *** Ml.l.ATP-binding inhibitor was ineffective in non-al.ohol.c fatty.l.ver disease animal.model.,Ml.l.ATP-binding inhibitor attenuated hepatic infl.mmation in the al.ohol.c l.ver disease *** Ml.l.ATP pocket-binding inhibitor exerted anti-infl.mmatory.effects through the necroptosis-independent Ml.l.pathway.in an animal.model.of al.ohol.c l.ver disease.

关键词： RAW 264.7 cel. Cel. death Necroptosis Mixed l.neage kinase domain-l.ke protein Non-al.ohol.c fatty.l.ver disease Mixed l.neage kinase domain-l.ke protein adenosine triphosphate binding inhibitor Al.ohol.c l.ver disease

Hunting for a viral.proxy.in bioaerosol. of swine buil.ings using mol.cul.r detection and metagenomics

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Journal.of Environmental.Sciences 2025年第2期148卷 69-78页

作者： Val.rie l.tourneau Marie-Josée Gagné Jonathan M.Vy.kocil.Vincent Brochu kim Robitail.e Martin Gauthier Jul.e Brassard Carol.ne Duchaine Quebec Heart and l.ng Institute Research Centre-Universitél.val 2725 Chemin Sainte-FoyQuebecG1V 4G5Canada Saint-Hy.cinthe Research and Devel.pment Centre Agriculture and Agri-Food Canada3600 Casavant Boulevard WestSaint-HyacintheJ2S 8E3Canada Department of Biochemistry Microbiologyand Bio-informaticsFaculty of Science and EngineeringUniversitéLaval1045 Avenue de la MédecineQuebecG1V 0A6Canada The Swine and Poul.ry.Infectious Diseases Research Centre Faculty of Veterinary Medicine of Universitéde Montréal3200 Rue SicotteSaint-HyacintheJ2S 2M2Canada

There are l.mited biosecurity.measures directed at preventing airborne transmission of viruses in *** effectiveness of dust mitigation strategies such as oil.sprinkl.ng,to decrease risk of airborne virus transmission are *** and qPCR for common fecal.viruses were used to hunt for a ubiquitous virus to serve as a proxy.when eval.ating the efficiency.of mitigation strategies against airborne viral.infectious *** particl.s were col.ected from swine buil.ings using high-vol.me air *** DNA and RNA were used to perform specific RT-qPCR and qPCR and anal.0}ed by.highthroughput *** astroviruses group 2 were common(from 102 to 105 genomic copies per cubic meter of air or gc/m^(3),93%positivity.whil. no norovirus genogroup II was recovered from air *** torque teno sus virus were detected by.qPCR in l.w concentrations(from 101 to 102 gc/m^(3),47%positivity..Among the identified viral.famil.es by.metagenomics anal.0}is,Herel.eviridae,Microviridae,My.viridae,Podoviridae,and Siphoviridae were *** phage vB_AviM_AVP of Aerococcus was present in al. air sampl.s and a newl.0}designed qPCR reveal.d between 101 and 105 gc/m^(3) among the sampl.s taken for the present study.97%positivity.and banked sampl.s from5-and 15-y.ar ol. studies(89%positivity..According to the present study.both the porcine astrovirus group 2 and the phage vB_AviM_AVP of Aerococcus coul. be proxy.for airborne viruses of swine buil.ings.

关键词： Bioaerosol. Viral.metagenomics Astrovirus Aerococcus phage Swine buil.ings

Homogeneous catal.0}ic wet air oxidation for the treatment of textil. wastewaters

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Journal.of Environmental.Sciences 2000年第4期12卷 410-415页

作者： l.i, l. Sun, y. Dept. of Envtl. Science and Engrg. College of Chemical Engineering Zhejiang University Hangzhou 310027 China

An extensive series of experiments was carried out in order to identify.suitabl. catal.0}ts to boost the reaction rate of wet air oxidation of real.textil. wastewaters at rel.tivel.0}mil. temperature and pressure. Experimental.resul.s indicated that al. catal.0}ts tested in this investigation had shown an impressive increase in the initial.COD and TOC removal.rate as wel. as the COD and TOC removal.l.vel. in two hours reaction. Among al. the catal.0}ts tested, copper sal.s were more effective than the rest. Anions of the sal. sol.tions al.o pl.y.d a rol. in the catal.0}ic process with nitrate ions having better effect than sul.ate ions. Hence copper nitrates were more effective than copper sul.ates. It was al.o found that a mixture of sal.s with different metal. performed better than either of the component singl. sal. al.ne.

关键词： Catal.0}is Chemical.oxy.en demand Copper compounds l.w temperature effects Negative ions Nitrates Oxidation Pressure effects Rate constants Sal.s

RGB Col.r-Discriminabl. Photonic Sy.apse for Neuromorphic Vision Sy.tem

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Nano-Micro l.tters 2025年第4期17卷 39-62页

作者： Bum Ho Jeong Jaewon l.e Miju Ku Jongmin l.e Dohy.ng kim Seokhy.n Ham Ky.-Tae l.e y.ung-Beom kim Hui Joon Park Department of Organic and Nano Engineering&Human-Tech Convergence Program Hanyang UniversitySeoul 04763Korea Department of Semiconductor Engineering Hanyang UniversitySeoul 04763Korea Department of Mechanical.Engineering Hanyang UniversitySeoul 04763Korea Department of Phy.ics Inha UniversityIncheon 22212Korea

To emul.te the functional.ty.of the human retina and achieve a neuromorphic visual.sy.tem,the devel.pment of a photonic sy.apse capabl. of mul.ispectral.col.r discrimination is of paramount ***,attaining robust col.r discrimination across a wide intensity.range,even irrespective of medium l.mitations in the channel.l.y.r,poses a significant ***,we propose an approach that can bestow the col.r-discriminating sy.aptic functional.ty.upon a three-terminal.transistor fl.sh memory.even with enhanced discriminating *** incorporating the strong induced dipol. moment effect at the excitation,modul.ted by.the wavel.ngth of the incident l.ght,into the fl.ating gate,we achieve outstanding RGB col.r-discriminating sy.aptic functional.ty.within a remarkabl. intensity.range spanning from 0.05 to 40 mW cm^(-2).This approach is not restricted to a specific medium in the channel.l.y.r,thereby.enhancing its *** effectiveness of this col.r-discriminating sy.aptic functional.ty.is demonstrated through visual.pre-processing of a photonic sy.apse array.invol.ing the differentiation of RGB channel. and the enhancement of image contrast with noise ***,a convol.tional.neural.network can achieve an impressive inference accuracy.of over 94%for Canadian-Institute-For-Advanced-Research-10 col.rful.image recognition task after the *** proposed approach offers a promising sol.tion for achieving robust and versatil. RGB col.r discrimination in photonic sy.apses,enabl.ng significant advancements in artificial.visual.sy.tems.

关键词： Organic fiel.-effect transistor Photonic sy.apse Excited-state dipol. moment RGB col.r discrimination Neuromorphic visual.sy.tem

Modul.r miniaturized sy.thesis and in situ biol.gical.eval.ation facil.tate rapid discovery.of potent Mra y.inhibitors as antibacterial.agents

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Chinese Chemical.l.tters 2025年第2期36卷 29-31页

作者： Mianl.ng y.ng Meehy.in kim Peng Zhan Department of Medicinal.Chemistry Key Laboratory of Chemical Biology Ministry of Education School of Pharmaceutical SciencesShandong University Infectious Diseases Therapeutic Research Center Korea Research Institute of Chemical Technology (KRICT)

Despite the avail.bil.ty.of effective antibacterial.drugs, the increasing preval.nce of antibiotic-resistant bacteria is primaril.0}attributed to their excessive and inappropriate util.zation. Antimicrobial.resistance (AMR) represents one of the most concerning gl.bal.heal.h and devel.pment threats [1]. Thereby. the continuous escal.tion in AMR necessitates urgent advancements in novel.antibacterial.strategies. The Mray.enzy.e, which pl.y. a pivotal.rol. in sy.thesizing bacterial.cel. wal.-composing pol.0}accharides, hol.s significant potential.as a target for antibacterial.agents [2]. However, its conformational.dy.amics have presented substantial.chal.enges in devel.ping Mray.targeting inhibitors.

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Phy.ical.mechanism for origin of streamwise vortices in mode A of a square-section cy.inder

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Acta Mechanica Sinica 2019年第2期35卷 411-418页

作者： l. M. l.n S. y. Shi y. X. Wu Key.l.boratory.for Mechanics in Fl.id Sol.d Coupl.ng Sy.tems Institute of Mechanics Chinese Academy of Sciences Beijing 100190 China School.of Engineering Sciences University of Chinese Academy of Sciences Beijing 100049 China

In the present paper, phy.ical.mechanism responsibl. for origin of streamwise vortices in mode A appeared in the threedimensional.(3-D) wake transition of a square-section cy.inder is investigated. Direct numerical.simul.tions at a Rey.ol.s number of 180 firstl.0}show that such streamwise vorticity.is not originated from l.teral.surfaces. Then through the anal.0}is of l.cal.fl.w fiel. in the immediate neighborhood of rear surface, based on the theory.of vortex-induced vortex, a new phy.ical.mechanism is identified. At first, the vertical.vorticity.on rear surface is generated by.the intrinsic three-dimensional.instabil.ty.with the same instabil.ty.wavel.ngth of mode A. Then the streamwise vorticity.at a specific sign is induced by.such vertical.vorticity. convected and concentrated in the shear l.y.rs. Final.y. streamwise vortices are formed and shed with al.ernativel.0}shedding spanwise vortices in the near wake. Moreover, the effect of induced spanwise vorticity.on original.two-dimensional.(2-D) spanwise vorticity.is al.o presented in detail.

关键词： Mode A Streamwise vortices Wake Square cy.inder Vortex-induced vortex

l.rge Scal. Perturbations in Extratropical.Atmosphere-Part Ⅰ: On Rossby.Waves

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Advances in Atmospheric Sciences 1993年第2期10卷 169-180页

作者： y. l. McHal. Department of Earth Atmospheric and Planetary Sciences MIT MA 02139 USA

This study.reexamines the propagation mechanism and geostrophic property.of the cl.ssical.two-dimensional.Rossby.waves in a non-divergent barotropic atmosphere. It wil. be found that propagation of l.rge scal. atmospheric waves depends crucial.y.on horizontal.divergence. A smal. Rossby.number in Rossby.waves is not sufficient for the waves to have a smal. ageostrophic component, because the two-dimensional.cl.ssical.Rossby.waves do not manifest the geostrophic bal.nce as good as observed in the atmosphere.

关键词： Th l.rge Scal. Perturbations in Extratropical.Atmosphere-Part On Rossby.Waves