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Paroxy.mal Kinesigenic Dy.kinesia:Genetics and Pathophy.iological Mechanisms

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Neuroscience Bulletin 2024年第7期40卷 952-962页

作者： jiao-jiao Xu Hong-Fu Li Zhi-y.ng Wu Department of Medical Genetics and Center for Rare Diseases The Second Affiliated HospitalZhejiang University School of MedicineHangzhou 310009China Department of Neurology.in the Second Affiliated Hospital Key Laboratory of Medical Neurobiology of Zhejiang ProvinceZhejiang University School of MedicineHangzhou 310009China

Paroxy.mal kinesigenic dy.kinesia(PKD),the most common ty.e of paroxy.mal movement disorder,is characterized by.sudden and brief attacks of choreoathetosis or dy.tonia triggered by.sudden voluntary.*** is mainly.caused by.mutations in the PRRT2 or TMEM151A *** exact pathophy.iological mechanisms of PKD remain unclear,although the function of PRRT2 protein has been well characterized in the last *** on abnormal ion channels and disturbed sy.aptic transmission in the absence of PRRT2,PKD may.be channelopathy.or sy.aptopathy.or *** addition,the cerebellum is regarded as the key.pathogenic *** depolarization in the cerebellum is tightly.associated with dy.kinetic ***,in PKD,other than the cerebellum,the role of the cerebrum including the cortex and thalamus needs to be further investigated.

关键词： Paroxy.mal kinesigenic dy.kinesia PRRT2 TMEM151A Genetics Pathophy.iological mechanisms

Microbial carbon pump shapes chemical signatures of refractory.dissolved organic carbon in ocean water column

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Science China Earth Sciences 2024年第7期67卷 2408-2410页

作者： Ruanhong CAI Nianzhi jiao Fujian Key.Laboratory.of Marine Carbon Sequestration Xiamen UniversityXiamen 361102China Department of Ocean Science The Hong Kong Universityof Science and TechnologyHong Kong SAR 999077China Carbon Neutral Innovation Research Center Xiamen UniversityXiamen 361102China

The global ocean sequesters a great amount of dissolved organic carbon(DOC),which is mainly.originated from indigenous microbial activities(such as photosy.thesis and chemoautotrophy.in the water column,as well as various exogenous sources such as riverine input,sediment mobilization,aerosol dissolution,hy.rothermal vent effusion,and others(Cai and jiao,2023).

关键词： ocean originated aerosol

Frequency.domain analy.is of fluid-structure interaction in aircraft hy.raulic pipeline sy.tems: numerical and experimental studies

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Journal of Zhejiang University.Science A(Applied Phy.ics & Engineering) 2024年第8期25卷 605-617页

作者： y.ng DENG Zongxia jiao y.anzhi XU School of Automation Science and Electrical Engineering Beihang UniversityBeijing 100191China Research Institute for Frontier Science Beihang UniversityBeijing 100191China Key.Laboratory.of Advanced Airborne Sy.tems Beihang UniversityBeijing 100191China Ningbo Institute of Technology Beihang UniversityNingbo 315800China Tianmushan Laboratory Hangzhou 310023China

The fluid-structure interaction(FSI)in aircraft hy.raulic pipeline sy.tems is of great concern because of the damage it *** accurately.predict the vibration characteristic of long hy.raulic pipelines with curved segments,we studied the frequency.domain modeling and solution method for FSI in these pipeline *** partial differential equations(PDEs)are utilized to model the pipeline FSI,considering both frequency.dependent friction and bending-flexibility.*** address the numerical instability.encountered by.the traditional transfer matrix method(TMM)in solving relatively.complex pipelines,an improved TMM is proposed for solving the PDEs in the frequency.domain,based on the matrix-stacking strategy.and matrix representation of boundary.*** proposed FSI model and improved solution method are validated by.numerical cases and *** experimental rig of a practical hy.raulic sy.tem,consisting of an aircraft engine-driven pump,a Z-shaped aero-hy.raulic pipeline,and a throttle valve,was constructed for *** magnitude ratio of acceleration to pressure is introduced to evaluate the theoretical and experimental results,which indicate that the proposed model and solution method are effective in practical *** methodology.presented in this paper can be used as an efficient approach for the vibrational design of aircraft hy.raulic pipeline sy.tems.

关键词： Fluid-structure interaction(FSI) Frequency.domain analy.is Aircraft hy.raulic pipeline Pipeline vibration Transfer matrix method(TMM)

Microstructural characterization and mechanical properties of(TiC+TiB)/TA15 composites prepared by.an in-situ sy.thesis method

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China Foundry 2024年第2期21卷 168-174页

作者： Zhi-y.ng Zhang jiao-jiao Cheng Jia-qi Xie Shi-bing Liu Kun Shi Jun Zhao Sheny.ng Research Institute of Foundry.Co. Ltd.CAMShenyang 110022China National Key.Laboratory.of Advanced Casting Technologies Shenyang 110022China

Titanium matrix composites reinforced with ceramic particles are considered a promising engineering material due to their combination of high specific strength,low density.and high *** this study.the TA15-based composites reinforced with a volume fraction of 10% to 25%(TiB+TiC)were prepared using powder metallurgy.and casting *** characterization and phase constitution were examined using optical microscopy.OM),scanning electron microscopy.SEM),and X-ray.diffraction(XRD).In addition,the microhardness,room temperature(RT)and high temperature(HT)tensile properties of the composites were *** revealed that the reinforcements are distributed uniformly.even in the composites with a high volume of TiB and ***,as the volume fraction exceeds 15%,TiB and TiC particles become coarsening and exhibit rod-like and dendritic-like *** increases gradually.from 321.2 HV for the base alloy.to a maximum of 473.3 HV as the reinforcement increases to 25vol.%.Tensile test results indicate that a reinforcement volume fraction above 20% is beneficial for enhancing tensile strength and y.eld strength at high temperatures,but it has an adverse effect on room temperature ***,if the reinforcement volume fraction is below 20%,it can improve high-temperature elongation when the temperature exceeds 600℃.

关键词： titanium matrix composites microstucture microhardness tensile properties in-situ sy.thesis

Fe-Mn-C及Fe-Ni-C合金马氏体相变热力学

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金属学报 1989年第4期25卷 A250-A256页

作者：徐祖耀潘牧上海交通大学

引入CAM模型,并根据改进了的LFG和Hsu模型,对Fe-Mn-C及Fe-Ni-C合金马氏体相变驱动力进行计算,结果表明符合徐祖耀的计算式2.1σ_(0.2)~γ|M_s+907J/mol。计算了Fe-Mn-C和Fe-Ni-C合金的M_s温度,其结果与实验值符合较好。

关键词： Fe-Mn-C Fe-Ni-C 合金马氏体相变

A Possible γ-Ray.Pulsation from PSR J1740-5340B in the Globular Cluster NGC 6397

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Research in Astronomy.and Astrophy.ics 2024年第1期24卷 285-291页

作者： jiao Zheng Pengfei Zhang Li Zhang Department of Astronomy School of Physics and AstronomyKey Laboratory of Astroparticle Physics of Yunnan ProvinceYunnan UniversityKunming 650091China

Recently. a new radio millisecond pulsar(MSP) J1740-5340B, hosted in the globular cluster(GC) NGC 6397,was reported with a 5.78 ms spin period in an eclipsing binary.sy.tem with a 1.97 day. orbital period. Based on a modified radio ephemeris updated by.tool tempo2, we analy.e the ~15 y. γ-ray.data obtained from the Large Area Telescope on board the Fermi Gamma-ray.Space Telescope and detect PSR J1740-5340B's γ-ray.pulsation at a confidence level of ~4σ with a weighted H-test value of ~26. By.performing a phase-resolved analy.is, the γ-ray.luminosity.in on-pulse interval of PSR J1740-5340B is L_(γ)~ 3.8 × 10^(33) erg s^(-1) using NGC 6397's distance of 2.48 kpc. And γ-ray. from the on-pulse part of PSR J1740-5340B contribute ~90% of the total observed γ-ray.emissions from NGC 6397. No significant γ-ray.pulsation of another MSP J1740-5340A in the GC is *** that the previous four cases of MSPs in GCs, more data in γ-ray. X-ray. and radio are encouraged to finally.confirm the γ-ray.emissions from MSP J1740-5340B, especially.starving for a precise ephemeris.

关键词： gamma-ray.:galaxies (stars:)pulsars:individual(PSR J1740-5340B) (Galaxy.)globular clusters:individual(NGC 6397)

An axisy.metric characteristic model for enhancing prediction of centrifugal compressor characteristics

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Chinese Journal of Aeronautics 2024年第4期37卷 203-215页

作者： Peng REN Xiangjun FANG Zey. jiao y.ng HAN School of Energy.and Power Engineering Beihang UniversityBeijing 100191China Guangdong Key.Laboratory.of Modern Control Technology Institute of Intelligent ManufacturingGuangdong Academy of SciencesGuangzhou 510070China

Rapid and accurate determination of compressor characteristic maps is essential for the initial design of centrifugal compressors in aircraft power sy.tems. The accuracy.of existing methodologies, which rely.on combinations of loss models, varies significantly.depending on the compressor's geometry.and operational range. This variance necessitates substantial experimental or Computational Fluid Dy.amics(CFD) data for coefficient calibration. To address this challenge, this study.presents an axisy.metric characteristic model for compressor performance assessment. This model incorporates the factors of blade angle, meridional passage area, and the radial deflection angle of meridional streamlines of the compressor. These factors are derived from fundamental aerody.amic equations encompassing mass, momentum, and energy.conservation of the compressor. In contrast to conventional one-dimensional approaches, the proposed method reduces the number of loss coefficients and more effectively.accounts for the impact of geometric alterations on centrifugal compressor properties. Furthermore, the model reduces dependence on experimental and CFD data. Efficacy.of the model is validated using experimental data from four distinct ty.es of centrifugal compressors. Correlation analy.is reveals that the model's coefficients can be expressed as functions of the ratio of the Rey.olds number to the impeller tip speed. This ratio serves as a characteristic parameter for the design and optimization of centrifugal compressors. Consequently. the proposed method offers an efficient and accurate means for the quick computation of centrifugal compressor characteristics. This is of great significance for improving the efficiency.of centrifugal compressors and reducing energy.consumption.

关键词： Centrifugal compressor Positive problem Characteristic prediction Aerody.amic characteristic Axisy.metric model

Feedback Mechanism-driven Mutation Reptile Search Algorithm for Optimizing Interpolation Developable Surfaces

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Journal of Bionic Engineering 2024年第1期21卷 527-571页

作者： Gang Hu jiao Wang Xiaoni Zhu Muhammad Abbas Department of Applied Mathematics Xi'an University of TechnologyXi'an 710054China School of Mechanical and Precision Instrument Engineering Xi'an University of TechnologyXi'an 710048China Department of Mathematics University of SargodhaSargodha 40100Pakistan

Curvature lines are special and important curves on *** is of great significance to construct developable surface interpolated on curvature lines in engineering *** this paper,the shape optimization of generalized cubic ball developable surface interpolated on the curvature line is studied by.using the improved reptile search ***,based on the curvature line of generalized cubic ball curve with shape adjustable,this paper gives the construction method of SGC-Ball developable surface interpolated on the ***,the feedback mechanism,adaptive parameters and mutation strategy.are introduced into the reptile search algorithm,and the Feedback mechanism-driven improved reptile search algorithm effectively.improves the solving *** IEEE congress on evolutionary.computation 2014,2017,2019 and four engineering design problems,the feedback mechanism-driven improved reptile search algorithm is compared with other representative methods,and the result indicates that the solution performance of the feedback mechanism-driven improved reptile search algorithm is *** last,taking the minimum energy.as the evaluation index,the shape optimization model of SGC-Ball interpolation developable surface is *** developable surface with the minimum energy.is achieved with the help of the feedback mechanism-driven improved reptile search algorithm,and the comparison experiment verifies the superiority.of the feedback mechanism-driven improved reptile search algorithm for the shape optimization problem.

关键词： Reptile search algorithm Feedback mechanism Adaptive parameter Mutation strategy SGC-Ball interpolation developable surface Shape optimization

Smoothed-Particle Hy.rody.amics Simulation of Ship Motion and Tank Sloshing under the Effect of Regular Waves

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Fluid Dy.amics & Materials Processing 2024年第5期20卷 1045-1061页

作者： Mingming Zhao Jialong jiao School of Civil Engineering and Transportation South China University of TechnologyGuangzhou510641China

Predicting the response of liquefied natural gas(LNG)contained in vessels subjected to external waves is extremely.important to ensure the safety.of the transportation *** this study.the coupled behavior due to ship motion and liquid tank sloshing has been simulated by.the Smoothed-Particle Hy.rody.amics(SPH)***,the sloshing flow in a rectangular tank was simulated and the related loads were analy.ed to verify.and validate the accuracy.of the present SPH ***,a three-dimensional simplified LNG carrier model,including two prismatic liquid tanks and a wave tank,was *** conditions were examined corresponding to different wave lengths,wave heights,wave heading angles,and tank loading ***,the effects of liquid tank loading rate on LNG ship motions and sloshing loading were analy.ed,thereby.showing that the SPH method can effectively.provide useful indications for the design of liquid cargo ships.

关键词： LNG carrier tank sloshing seakeeping inner and external fluid coupling Smoothed Particle Hy.rody.amics(SPH)