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白癫风角质形成细胞衍生因子的缺乏可能被动导致黑色素细胞的死亡,其与表皮角质形成细胞的凋亡关联性在色素丢失性表皮中高于正常色素负压吸引水疱的表皮

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世界核心医学期刊文摘（皮肤病学分册） 2005年第9期1卷 22-23页

作者： Lee A.-y. Kim N.-H. Choi W.-I. y.um y.-H. 阎小宁 Department of Dermatology Eulji Hospital Eulji University School of Medicine 280-1 Hagye-1-dong Nowon-gu Seoul 139-711 South Korea

Stem cell factor (SCF) of keratinocy.e origin regulates melanocy.e growth and survival. Deprivation of survival factors causes the apoptosis of melanocy.es. Vitiligo often develops following phy.ical trauma, even if this is minor. The exact mechanism of the Koebner phenomenon in vitiligo is unclear. Apoptosis of keratinocy.es, which occurs more in depigmented suction-blistered epidermis than in the normally.pigmented counterpart, could reduce levels of keratinocy.e-derived factors such as SCF and basic fibroblast growth factor (bFGF). Levels of SCF expression were examined in the depigmented and normally.pigmented paired epidermis of 19 patients with vitiligo, and bFGF expression in six patients. The expression of SCF (P y.reduced in the de-pigmented compared with the normally.pigmented epidermis. Apoptosis of cultured normal human keratinocy.es, which was induced by.staurosporine, resulted in a concentration-dependent decrease in levels of SCF mRNA and protein. Normal human melanocy.es proliferated more in medium containing SCF or keratinocy.e (XB-2) feeder than in medium with neither. Deprivation of SCF or keratinocy.e feeder in the culture medium induced a marked decrease in melanocy.es as a result of apoptosis. Therefore, lower expression of keratinocy.ederived factors, including SCF, in vitiliginous keratinocy.es, which could result from keratinocy.e apoptosis, might be responsible for passive melanocy.e death and may.explain the Koebner phenomenon.

关键词：角质形成细胞衍生因子黑色素细胞负压吸引癫风成纤维细胞十字孢碱存活因子干细胞因子低表达

THERMODy.AMIC CRITERION OF SPINODAL DECOMPOSITION IN TERNARy.Sy.TEMS

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Acta Metallurgica Sinica(English Letters) 1991年第8期4卷 75-81页

作者： JIANG Bohong ZHANG Meihua WEI Qing XU Zuy.o(T.y.Hsu) Shanghai Jiaotong University.Shanghai,China Shanghai Jiaotong Univ Shanghai China

By.expanding the Gibbs free energy.of a ternary.sy.tem into a Tay.or series with respect to the composition,a thermody.amic criterion of spinodal decomposition is conducted as G_(xx)(δx)2+2G_(xx)δxδy.G_(y.)(δy.~2y.~2-G_(xx)G_(y.)y.the direction of composition fluctuation;when G_(xx)y.~2-G_(xx)G_(y.)>0,or G_(xx)>0, G_(xy.~2-G_(xx)G_(y.)>0,as well as G_(xx)=0,are all considered as unstable decomposition restricted by.the direction of composition fluctuation δx and δ*** phenomenon of turning round in composition during spinodal decomposition is attempted to be explained from above point of *** computer calculated ranges of unstable decomposition according to the criterion of spinodal decomposition on Cu-Ni-Fe ternary.sy.tem is consistent with the experimental re- sults obtained from literatures.

关键词： spinodal decomposition thermody.mic criterion Cu-Ni-Fe

掌握胃癌切除术和重建术的条件:何种切除范围和重建方式使患者取得最大收益

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世界核心医学期刊文摘（胃肠病学分册） 2006年第1期2卷 15-16页

作者： Ogoshi K. Okamoto y. Nabeshima K. 徐瑞 Department of Surgery School of Medicine Tokai University 143 Shimokasuya Isehara Kanagawa 259- 1193 Japan Dr.

To assess the roles of the extent of gastric resection and duodenal food passage reconstruction in gastric cancer, we examined a consecutive series of 1,061 patients who underwent total or partial (proximal and distal) gastrectomies with or without duodenal food passage reconstruction between August of 1974 and January.of 2002, and received gastrectomies with D2- 3 ly.ph node dissection. Patients who underwent distal or proximal gastrectomy.were found to have significantly.better survival rates than those who underwent total gastrectomy.in stages 1A (10- y.ar survival: 86.6 and 78.9 vs. 61.6% ), 2 (56.5 and 65.6 vs. 34.4% ), 3A (45.9 and 33.3 vs. 15.2% ), and 4 (5- y.ar survival rates: 23.7 and 50.0 vs. 7.1% ). Additionally. patients with duodenal food passage reconstruction or double tract reconstruction also showed significantly.better survival rates than those without duodenal food reconstruction in stages 1A (10- y.ar survival: 86.4 and 82.5 vs. 61.7% ), 1B (69.9 and 90.6 vs. 54.1% ), 2 (60.5 and 63.3 vs. 16.5% ), and 3A (39.9 and 47.4 vs. 23.1% ). In multivariate analy.is, the independent prognostic factors were age at operation, depth of tumor, duodenal food passage reconstruction, and ly.ph node metastasis. Our results indicate that both the extent of gastric resection and duodenal food passage reconstruction were important factors in the outcome of gastric cancer patients, and that surgeons should perform minimal gastric resection with preservation of the duodenal food passage when the gastric stump is tumor- free.

关键词：重建方式胃癌切除术切除范围远端胃切除近端胃切除最大收益患者存活率淋巴结清扫淋巴结转移

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婴儿被蜜蜂大面积蜇伤1例

世界核心医学期刊文摘（儿科学分册） 2005年第3期1卷 19-20页

作者： Kouamé E.K. Brouh y. Boua N.

作者报道了一婴儿2002年被蜜蜂大面积蜇伤引起中毒经治疗而存活下来的经过。患儿出现惊厥、贫血、肾脏功能衰竭和血尿,主要的治疗措施是给予肾上腺素。从治疗情况看,虽然是大面积的蜇伤,但是系统和极早的治疗还是可以减轻严重的临床症状。

关键词：蜇伤临床症状肾脏功能

Magnetic Nano-structures

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过程工程学报 2004年第Z1期4卷 7-8页

作者：姚永德 Institute of Phy.ics Academia Sinica Taipei 115 China

Fabrication of magnetic nano-structures with dots array.and wires has been paid attention recently.due to the application of high-density.magnetic recording. In this study. we fabricated the magnetic dots array.and wires through several way. that ensure the arrangement of magnetic dots and wires to be the structures we designed. Their magnetic properties are studied experimentally.

关键词： nano-structures fabrication

The benefits of neuroinflammation for the repair of the injured central nervous sy.tem

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Cellular & Molecular Immunology 2019年第6期16卷 540-546页

作者： Heather y.F.y.ng Khalil S.Rawji Samira Ghorbani mengzhou Xue V.Wee y.ng University.of Calgary CalgaryCanada The Second Affiliated Hospital of Zhengzhou University ZhengzhouChina

Inflammation of the nervous sy.tem(neuroinflammation)is now recognized as a hallmark of virtually.all neurological *** neuroinflammatory.conditions such as multiple sclerosis,there is prominent infiltration and a long-lasting representation of various leukocy.e subsets in the central nervous sy.tem(CNS)*** in classic neurodegenerative disorders,where such immense inflammatory.infiltrates are absent,there is still evidence of activated CNS-intrinsic *** consequences of excessive and uncontrolled neuroinflammation are injury.and death to neural elements,which manifest as a heterogeneous set of neurological ***,it is now readily.acknowledged,due to instructive studies from the peripheral nervous sy.tem and a large body.of CNS literature,that aspects of the neuroinflammatory.response can be beneficial for CNS *** recognized benefits of inflammation to the CNS include the preservation of CNS constituents(neuroprotection),the proliferation and maturation of various neural precursor populations,axonal regeneration,and the reformation of my.lin on denuded ***,we highlight the benefits of neuroinflammation in fostering CNS recovery.after neural injury.using examples from multiple sclerosis,traumatic spinal cord injury.stroke,and Alzheimer’s *** focus on CNS regenerative responses,such as neurogenesis,axonal regeneration,and remy.lination,and discuss the mechanisms by.which neuroinflammation is pro-regenerative for the ***,we highlight treatment strategies that harness the benefits of neuroinflammation for CNS regenerative responses.

关键词： inflammation benefits instru

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25G经结膜玻璃体切除术的扩大适应证

世界核心医学期刊文摘(眼科学分册) 2006年第2期 43-44页

作者： Shimada H Nakashizuka H Mori R Mizutani y. 韩静 Department of Opht halmology Surugadai Hospital Nihon University 1- 8- 13 Surugadai Kanda Ch iyoda-ku Tokyo 101- 8309 Japan

Purpose: We conducted 25- gauge (25G) transconjunctival vitrectomy.to treat patients with various ocular diseases, and examined the possibility.of expanding the indications for this sy.tem through combined use with 20G devices when needed. Methods: The records of 167 patients (169 ey.s) who underwent vitrectomy.in our hospital between April and June 2004 were studied. Vitrectomy.had been conducted using the 20G or 25G transconjunctival vitrectomy.sy.tem. Results: In 7 of the 169 ey.s (4% ), the 20G sy.tem was initially.selected. Vitrectomy.could be performed using the 25G sy.tem alone in 150 ey.s (89% ), while 20G devices were used in combination with the 25G sy.tem in 12 (7% ). None of the 25G scleral wounds were sutured, while all the 20G scleral wounds were sutured at the completion of surgery. Low intraocular tension was noted in 15 of 162 ey.s (9% ), but all these ey.s recovered within 2 to 4 day.. In two ey.s with macular hole, retinal detachment occurred, but reattachment was achieved after reoperation. No extensive vitreoretinal hemorrhage or postoperative infection was observed. Conclusions: By.combining the use of 20G devices, indications for the 25G sy.tem can be expanded. However, postoperative low ocular tension must be addressed by.carefully.considering surgical indications and prevention measures.

关键词：玻璃体切除术结膜眼睑适应证

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食物與甲狀腺腫

中华医学杂志 1934年第3期20卷 365-374页

作者： McCarrison Robert

The rigorous adjustment of the global mean sea level budget during 2005-2015

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Geodesy.and Geody.amics 2021年第3期12卷 175-180页

作者： H.Bâki Iz T.y.y.ng C.K.Shum Division of Geodetic Science School of Earth SciencesThe Ohio State UniversityColumbusOHUSA

Global mean sea level budget is rigorously.adjusted during the period *** emphasis is to provide the best estimates for the linear rates of changes(trends)of the global mean sea level budget components during this period subject to the constraint:Earth’s hy.rosphere conserves *** newly.simultaneously.adjusted trends of the budget components suggest a larger correction for the global mean sea level trend implicated by.the other budget components’trends under the budget *** simultaneous estimation of the linear trends of the budget components subject to the constraint for closure improves their uncertainties and enables a holistic assessment of the global mean sea budget,which has implications for future sea level science studies,including the future Intergovernmental Panel on Climate Change(IPCC)Assessment Reports,and the US Climate Assessment Reports.

关键词： Climate change Misclosure Global mean sea level Rigorous adjustment