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对比MRI与CT诊断不同病理分期前列腺癌的准确率

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中国性科学 2018年第12期27卷 12-14页

作者：陆黎孙宗琼李超凡杨文霞谭旭艳无锡市第五人民医院放射科江苏无锡214000 无锡市第四人民医院放射科江苏无锡214000 无锡市第四人民医院妇产科江苏无锡214000 江苏省肿瘤医院超声科南京210009

目的:探究MRI与CT在不同病理分期前列腺癌临床诊断中的应用效果。方法:选择2015年4月至2017年4月无锡市第五人民医院收治的不同病理分期前列腺癌患者63例,A期、B期患者23例,C期、D期患者40例。分别实施MRI与CT检查,并以病理组织活检结... 详细信息

目的:探究MRI与CT在不同病理分期前列腺癌临床诊断中的应用效果。方法:选择2015年4月至2017年4月无锡市第五人民医院收治的不同病理分期前列腺癌患者63例,A期、B期患者23例,C期、D期患者40例。分别实施MRI与CT检查,并以病理组织活检结果作为金标准,对比分析两种诊断方法在不同病理分期患者诊断中的准确率。结果:与病理组织活检结果进行比较,可得对于前列腺癌A期、B期患者,MRI与CT检查在诊断准确率方面存在明显差异,MRI的诊断符合率显著高于CT检查,差异具有统计学意义(P 0. 05)。结论:MRI与CT在不同病理分期前列腺癌临床诊断中均具有一定的应用价值,但对早期前列腺癌患者,MRI检查体现出明显的应用优势。

关键词：前列腺癌病理分期临床诊断 MRI CT 准确率

腰椎间盘突出症患者疼痛信念与生活质量的相关性分析

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护理学杂志 2016年第2期31卷 51-53页

作者：李星凤熊钰邓诗佳李怡臻刘跃晖谭旭妍湖南师范大学医学院护理系湖南长沙410013 湖南师范大学第二附属医院骨二科湖南师范大学第一附属医院护理部

目的了解腰椎间盘突出症患者疼痛信念、生活质量现状及两者的相关性。方法选取长沙市2所三级甲等医院住院的207例腰椎间盘突出症患者为调查对象,运用疼痛信念与感知量表、简明健康状况调查量表（SF-36）进行调查。结果腰椎间盘突出症患... 详细信息

目的了解腰椎间盘突出症患者疼痛信念、生活质量现状及两者的相关性。方法选取长沙市2所三级甲等医院住院的207例腰椎间盘突出症患者为调查对象,运用疼痛信念与感知量表、简明健康状况调查量表（SF-36）进行调查。结果腰椎间盘突出症患者疼痛信念得分为-20-31（5.36±9.94,M=6.00）分,其中认为疼痛不可解除得分最高,认为会持续疼痛、认为疼痛不可解除及疼痛信念总分与生活质量各维度呈负相关（P〈0.05,P〈0.01）。结论护理人员应重视患者的疼痛信念对生活质量的影响,提高患者对疼痛的认识,增强患者积极的疼痛信念,从而提高患者的生活质量。

关键词：腰椎间盘突出症疼痛疼痛信念生活质量

Brain Mechanisms Underlying Panic Attack and Panic Disorder

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Neuroscience Bulletin 2024年第6期40卷 795-814页

作者： xuyan Guan Peng Cao Tsinghua Institute of Multidisciplinary Biomedical Research Tsinghua UniversityBeijing102206China National Institute of Biological Sciences(NIBS) Beijing102206China

Panic disorder is a psychiatric disorder characterized by recurrent panic attacks,with a prevalence of~4%in the general population,causing heavy personal and socioeconomic *** similarities of animal defense responses to clinical panic attack symptoms in humans make it possible to translate neuroanatomical pathways identified in animal studies to panic disorder in ***,in this review we first present a basic overview of panic disorder in humans including the main subtypes,models commonly used to trigger panic attacks,related hypotheses,the neurotransmitter systems that may be involved,and the current clinical treatments to give the reader a comprehensive understanding of panic *** animal section introduces the models that trigger panic-like behavior in animals and the brain regions that may be involved,providing insights for future elucidation of the neural circuit mechanisms behind panic attacks.

关键词： Panic disorder Panic attack Defense responses Animal studies Humans

Shuffled Mutation Glowworm Swarm Optimization and Its Application

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Chinese Journal of Electronics 2019年第4期28卷 822-828页

作者： WANG Hongbo REN Xuena TU xuyan School of Computer and Communication Engineering Beijing Key Lab of Knowledge Engineering for Materials ScienceUniversity of Science and Technology Beijing Institute of Information Engineering Chinese Academy of Sciences

If the glowworm individual has no memory during its movement, and the decision of next direction is limited to its current position. It is precisely these reasons mentioned above that make the basic Glowworm Swarm Optimization easy to trap into the local optimum. In order to solve the problem, this paper suggests a Shuffled mutation glowworm swarm optimization(SMGSO), which combines the thought of Shuffled Frog Leaping with Glowworm Swarm Optimization. Making use of a grouping idea of Shuffled Mutation, the glowworm swarm is divided into several subgroups. The location updating of each individual is not only influenced by the brightest node in neighbour scope, but also by the brightest one in their local subgroup, meanwhile the locations of those isolated nodes are updated by the difference mutation of the global optimum and local optimal. In group shuffling stage, an orthogonal strategy can guide the whole population to generate their offspring. The performance of this proposed approach is examined by well-known10 benchmark functions, and its obtained results are compared with what other variants hold. The experimental analysis show that the Shuffled mutation glowworm swarm optimization is effective and outperforms other variants in terms of solving multi-modal function optimization problems, and the proposed approach can improve the positioning accuracy of the centroid localization.

关键词： Orthogonal strategy Shuffled frog leaping Wireless sensor centroid location

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基于史学和模式语言的清真大寺遗产价值研究

华中建筑 2025年第1期43卷 175-179页

作者：吕缓缓方旭艳内蒙古工业大学建筑学院

清真大寺作为呼和浩特伊斯兰教代表性历史建筑遗产,其建造翻新的演变历程反映了伊斯兰建筑在多元文化的共同影响下具有混溶性的特点。通过史料分析、图形学分析和比较研究的方法,以传统史学和建筑模式语言的视角回归建筑本身,着眼于建... 详细信息

清真大寺作为呼和浩特伊斯兰教代表性历史建筑遗产,其建造翻新的演变历程反映了伊斯兰建筑在多元文化的共同影响下具有混溶性的特点。通过史料分析、图形学分析和比较研究的方法,以传统史学和建筑模式语言的视角回归建筑本身,着眼于建筑布局、立面构图以及材料装饰的对比溯源,总结出其建筑遗产价值主要体现在:记录叙事性历史信息、传承地域性技术表达、深化多元建筑要素融合、促进文旅更新发展等方面,为伊斯兰建筑遗产及其周边街道开发再利用提供研究思路与理论支持。

关键词：清真寺史学视角建筑模式语言伊斯兰教建筑建筑遗产价值

低聚甘露糖增强短双歧杆菌抑制具核梭杆菌生长的机制研究

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食品工业科技 2025年第1期46卷 163-170页

作者：张旭妍刘瑞洁赵博许晓曦东北农业大学食品学院黑龙江哈尔滨150030 教育部乳品重点实验室黑龙江哈尔滨150030

为探究双歧杆菌与低聚糖协同抑制具核梭杆菌作用及机理,采用6种常见双歧杆菌(动物双歧杆菌、长双歧杆菌、婴儿双歧杆菌、短双歧杆菌、两歧双歧杆菌、青春双歧杆菌)代谢6种不同结构且应用广泛的低聚糖(低聚甘露糖、低聚半乳糖、低聚异麦... 详细信息

为探究双歧杆菌与低聚糖协同抑制具核梭杆菌作用及机理,采用6种常见双歧杆菌(动物双歧杆菌、长双歧杆菌、婴儿双歧杆菌、短双歧杆菌、两歧双歧杆菌、青春双歧杆菌)代谢6种不同结构且应用广泛的低聚糖(低聚甘露糖、低聚半乳糖、低聚异麦芽糖、低聚果糖、低聚乳果糖、阿拉伯半乳聚糖),通过硫化氢的生成与生物膜的抑制,确定最佳抑制具核梭杆菌组合,通过扫描电镜、透射电镜与流式细胞仪分析具核梭杆菌菌体细胞完整性,研究抑菌机理,并探讨其酸性代谢产物对具核梭杆菌的抑制作用影响,测定其短链脂肪酸产量,此外还挖掘了双歧杆菌潜在细菌素基因簇。结果显示,低聚甘露糖促进短双歧杆菌抑制具核梭杆菌效果最佳,其组合可显著减少硫化氢的产生与生物膜的形成,与空白对照相比,在添加量达到20%时,对具核梭杆菌的抑制率可达到63.16%±4.48%,其表观结构明显损伤,蛋白和核酸流出,细胞膜的完整性和通透性被破坏。这种抑菌效果会随着上清液pH向中性环境的靠近而下降,表明上清液中酸性代谢产物在发挥抑菌效果中起重要作用,上清液中乙酸、丙酸、丁酸、戊酸分别含量为26.112、10.829、5.106、5.232 mmol/L。此外基因预测到短双歧杆菌包含2个潜在的细菌素合成基因簇。综上,低聚甘露糖配合短双歧杆菌的合生元组合或可作为一种安全、有效的具核梭杆菌生物防控抑制剂,为预防及辅助治疗结直肠癌等肿瘤疾病提供更为安全有效的新方法。

关键词：双歧杆菌低聚糖抑菌机制短链脂肪酸具核梭杆菌

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A Many-Objective Evolutionary Algorithm with Spatial Division and Angle Culling Strategy

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Chinese Journal of Electronics 2021年第3期30卷 437-443页

作者： WANG Hongbo YANG Fan TIAN Kena TU xuyan School of Computer and Communication Engineering Beijing Key Lab.of Knowledge Engineering for Materials ScienceUniversity of Science and Technology Beijing

In a specific project, how to find a reasonable balance between a plurality of objectives and their optimal solutions has always been an important aspect for researchers. As a trade off between fast convergence and a rich diversity, a Many-objective evolutionary algorithm based on a spatial division and angle-culling strategy(Ma OEA-SDAC) is proposed. In the reorganization stage, a restricted matching selection can enhance the reproductivity. In the environment selection stage, a space division and angle-based elimination strategy can effectively improve the convergence and diversity imbalance of its solution set. Through detailed experiments and a comparative analysis of the proposed Ma OEA-SDAC with five other state-of-the-art algorithms on classical benchmark problems, the effectiveness of Ma OEA-SDAC in solving high-dimensional optimization problems has been verified.

关键词： reasonable balance many-objective evolutionary algorithm convergence environment selection stage angle culling strategy elimination strategy spatial division rich diversity Pareto optimisation angle-culling strategy diversity imbalance restricted matching selection specific project evolutionary computation fast convergence reorganization stage MaOEA-SDAC space division optimal solutions

The Mechanical Properties and Hydration Characteristics of Cement Pastes Containing Added-calcium Coal Gangue

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Journal of Wuhan University of Technology(Materials Science) 2008年第2期23卷 254-258页

作者： LI Dongxu SONG xuyan College of Material Science EngineeringNanjing University of Technology Nanjing 210009 China Department of Civil Engineering University of Science and Technology and Suzhou 215011 China

The mechanical properties of several kinds of coal gangue calcined with limestone were Researched so as to find the optimum way of calcinations with limestone. Microstructure and property of hydration process of cement pastes containing added-calcium coal gangue were analyzed by means of scanning electron microscope （SEM） and method of mercury in trusion poremeasurement （MIP）, etc. The experiment can approve those results： when proper amounst of gypsum and fluorite were taken as mineralizers in the course of calcinations of added-calcium coal gangue, activity of coal gangue can be effectively improved. The results of mechanical property and structural characteristic such as hydration process, hydration product and microstructure etc. of cement pastes containing added-calcium coal gangue are consistent.

关键词： coal gangue calcinations with limestone scanning electron microscope pore structure study

An optimization model for fragmentation-based routing in delay tolerant networks

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Science China(Information Sciences) 2016年第2期59卷 185-200页

作者： xuyan BAO Yong ZHANG Da GUO Mei SONG School of Electronic Engineering Beijing University of Posts and Telecommunications

The explosive growth of mobile data traffic has raised big penetration to cellular network. Fortunately, offloading part of traffic through Delay Tolerant Network(DTN) would be a promising option to relieve load pressure. However, the existing routing strategies designed for DTNs are inappropriate in offloading scenario, where i) large data item would take on the dominance of mobile traffic, ii) centralized control can be exploited with merge between DTN and cellular network. To improve the routing performance of large data transmission, we propose a novel optimization model by creating two-tier solution space based on fragmentation,maximizing the probability that the requested data item is successfully delivered before expiration, taking limited buffer space as constraint metric. Moreover, a specific routing scheme is instantiated from our model, which is supported by uniform fragmentation and fine-grained path selection. Extensive trace-driven simulations show that our scheme is more appropriate for offloading case with outstanding performance in terms of replication overhead and acceptable routing capability.

关键词： multi-path routing delay tolerant networks optimization model data offloading stochastic orderings