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interfacial DMi in Fe/Pt thin films grown on different buffer layers

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Chinese Physics B 2024年第4期33卷 712-718页

作者：张文君魏菲刘冰周阳康仕寿孙兵 School of Physics and Electronic information Weifang UniversityWeifang 261061China School of Physics and State Key Laboratory of Crystal Materials Shandong UniversityJinan 250100China

We study the interfacial Dzyaloshinskii-Moriya interactions(i-DMi)of Fe/Pt bilayers grown on Si substrates with MgO,SiO_(2),or Ta each as a buffer layer on the basis of wave-vector-resolved Brillouin light scattering(BLS)*** obtained i-DMi energy values for Fe/Pt on MgO,Ta,and SiO_(2) buffer layers are 0.359,0.321,and 0.274 mJ/m~2,*** large i-DMi value observed in Fe/Pt system on the MgO buffer layer can be attributed to the good interfacial quality and the Rshaba effect at the MgO/Fe ***,the MgO/Fe/Pt system,benefiting from better sample quality,exhibits a lower damping ***,layer-resolved first-principles calculations are carried out to gain a more in-depth understanding of the origin of the i-DMi in the Fe/Pt *** results indicate that in the Fe(110)/Pt(111)system,the substantial DMi energy between Fe spins at the interface is related to a significant change in spin-orbit coupling(SOC)energy in the neighboring Pt *** contrast,for the MgO(002)/Fe(002)system,both the DMi and its related SOC energy are concentrated at the interfacial Fe *** investigation will provide a valuable insight into the spintronic community in exploring novel devices with chirality dependence.

关键词： Fe/Pt i-DMi BLS ferromagnetic resonance magnetic relaxation

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关于一些行列式与积和式

数学学报（中文版） 2024年第2期67卷 286-295页

作者：孙智伟南京大学数学系南京210093

本文研究了一些行列式与积和式.特别地,我们探讨了新型行列式det[(i^(2)+cij+dj^(2))^(p-2)]0≤i,j≤p-1与det[(i^(2)+cij+dj^(2))p-2]1≤i,j≤p-1模奇素数p,其中c与d为整数.我们也提出一些猜想以供进一步的研究.

关键词：行列式积和式 p进同余式勒让德符号

Acceptance and Factors Associated With Participation in Functional Cure–Related Trials Among People Living With HiV: A Cross-sectional Study in Southern China

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infectious Microbes & Diseases 2024年第1期6卷 11-19页

作者： Zhaomin Deng Minjuan Shi Yue Yuan GuangjinCao Chunyan Wen Lijuan Chen Xueying Fan Linan Wu Jianhui Yuan Huachun Zou Linghua Li Caijun sun School of Public Health(Shenzhen) Shenzhen Campus of Sun Yat-sen UniversityShenzhenChina Department of Diseases Control Panyu District Center for Disease Control and PreventionGuangzhouChina infectious Disease Center Guangzhou Eighth People's HospitalGuangzhou Medical UniversityGuangzhouChina Nanshan District Center for Disease Control and Prevention ShenzhenChina Key Laboratory of Tropical Disease Control(sun Yat-sen University) Ministry of EducationGuangzhouChina

HiV remains a global health challenge,and research efforts directed towards a functional cure require people living with HiV(PLHiV)in-volvement in clinical *** study assessed willingness to participate in HiV functional cure–related clinical trials and associated factors among PLHiV in Guangzhou,China,using a questionnaire survey *** analyzed responses from 718 questionnaires,finding that 71.2%were willing to participate in Phase Ⅲtrials,while 51.7%were willing to participate in Phase i trials and 42.9%expressed acceptability for analytic treatment *** logistic regression demonstrated that male PLHiV,those with awareness of functional cure,and PLHiV,who had been on antiretroviral therapy(ART)for less than 1 year,were more willing to partic-ipate in Phase Ⅲ*** with a body mass index greater than 24,and those without resistance to ART drug were more willing to participate in Phase i *** major motivations for participation in Phase Ⅲtrials were access to cutting-edge treatments(62.6%)and supporting research(55.3%).Safety was the main concern contributing to *** study revealed a high willingness to participate in HiV functional cure–related trials among PLHiV in Guangzhou,China,and willingness varied across different trial phases and was influenced by multiple *** study provides valuable references for future clinical trial recruitment strategies and public health policy formulation.

关键词： people living with HiV functional cure clinical trials willingness

基于实稳定方法的原子核单粒子共振相对论Hartree-Fock模型

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物理学报 2024年第6期73卷 166-175页

作者：杨威丁士缘孙保元兰州大学教育部稀有同位素前沿科学中心兰州730000 兰州大学核科学与技术学院兰州730000

利用坐标空间的实稳定方法,在相对论Hartree-Fock(RHF)理论框架下发展了原子核单粒子共振态结构模型.具体以^(120)Sn的低激发中子共振态为例,探讨了交换项在影响共振能量、宽度以及自旋-轨道劈裂等性质中的作用.相较于一般的相对论平均... 详细信息

利用坐标空间的实稳定方法,在相对论Hartree-Fock(RHF)理论框架下发展了原子核单粒子共振态结构模型.具体以^(120)Sn的低激发中子共振态为例,探讨了交换项在影响共振能量、宽度以及自旋-轨道劈裂等性质中的作用.相较于一般的相对论平均场(RMF)理论,RHF中交换项的引入改变了核介质中有效核力的动力学平衡机制,进而影响共振态单粒子势的描述.对于一般的宽共振态,这可能导致相对更低的共振能量和更小的共振宽度.此外,对^(120)Sn共振态中νi_(13/2)与νi_(11/2)自旋伙伴态,还分析了交换项对其自旋-轨道劈裂的相关效应.与束缚态情形相比,共振态中自旋伙伴态的波函数可能存在显著区别,单粒子有效势与能量也相应发生改变.结果表明,不仅自旋-轨道相互作用,单粒子有效势中其他成分也是影响共振态自旋-轨道劈裂的重要因素.

关键词：单粒子共振态实稳定方法相对论Hartree-Fock理论自旋-轨道劈裂

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基于GBS测序对无芒雀麦资源群体的解析

草业科学 2024年第5期41卷 1149-1160页

作者：孙雪孙强周乐朝木力嘎孙宇阳张延辉西部干旱荒漠区草地资源与生态教育部重点实验室新疆乌鲁木齐830052 新疆草地资源与生态实验室新疆乌鲁木齐830052 新疆农业大学草业学院新疆乌鲁木齐830052 新疆维吾尔自治区草原总站新疆乌鲁木齐830049 新疆喀什地区草原站新疆喀什844599

无芒雀麦(Bromus inermis)是一种重要的牧草,但目前还缺乏从分子水平对于种质资源的亲缘关系的解析。本研究基于GBS测序技术,对采自不同区域的67份无芒雀麦种质资源亲缘关系和遗传结构进行分析。结果表明:1)无芒雀麦表型存在丰富的多样... 详细信息

无芒雀麦(Bromus inermis)是一种重要的牧草,但目前还缺乏从分子水平对于种质资源的亲缘关系的解析。本研究基于GBS测序技术,对采自不同区域的67份无芒雀麦种质资源亲缘关系和遗传结构进行分析。结果表明:1)无芒雀麦表型存在丰富的多样性,比较21个表型指标变异特征,变异系数为12.67%~54.17%。2)基于表型特征将67份材料可分为4个类群,类群Ⅰ、Ⅱ和Ⅲ均为单一材料,分别为N06(新疆)、M09(内蒙古)和QG07(甘肃)。类群Ⅳ包含64份材料,各地区均有。基于SNP位点信息构建的系统发育进化树和主成分分析,将67份无芒雀麦种质资源分成4个类群:类群Ⅰ,N08,属于新疆北部山地;类群Ⅱ为5份亲缘关系密切的疆外区域种质;类群Ⅲ为39份与其他类群种质亲缘关系较远的材料组成;类群Ⅳ由22份新疆区域种质组成。两种方法对材料的划分具有相似性。3)根据GBS测序序列,发现SNP的变异类型主要为碱基转换,且转换占比高于颠换,转换占76.02%,颠换占23.98%。4)基于不同材料SNP的分布特征,通过群体遗传结构分析将无芒雀麦材料划分为两个类群,类群Ⅰ主要来自于新疆,类群Ⅱ包含全国各地材料,67份材料存在群体结构。以上结果为无芒雀麦种质资源的鉴定评价、关联分析、系统分类及品种选育等奠定了基础。

关键词：无芒雀麦简化基因组测序种质资源群体结构亲缘关系表型性状

ON A UNiVERSAL iNEQUALiTY FOR APPROXiMATE PHASE iSOMETRiES

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Acta Mathematica Scientia 2024年第3期44卷 823-838页

作者：戴端旭阙海新孙龙发郑本拓 School of Science Jimei UniversityXiamen361021China Hebei Key Laboratory of Physics and Energy Technology School of Mathematics and PhysicsNorth China Electric Power UniversityBaoding071003China Department of Mathematical Sciences University of MemphisMemphisTN38152USA

Let X and Y be two normed *** U be a non-principal ultrafilter on *** g:X→Y be a standard ε-phase isometry for someε≥ 0,i.e.,g(0)=0,and for all u.v ∈ X,||‖g(u)+g(v)‖±‖g(u)-g(v)‖|-|‖u+v‖±‖u-v‖| |≤ε.The mapping g is said to be a phase isometry provided that ε=*** this paper,we show the following universal inequality of g:for each u^(*) ∈ w^(*)-exp ‖u^(*)‖B_(x^(*)),there exist a phase function σ_(u^(*)):X→{-1,1} and φ ∈ Y^(*) with ‖φ‖=‖u^(*)‖≡α satisfying that|(u^(*),u)-σ_(u^(*))(u))|≤5/2εα,for all u ∈ *** particular,let X be a smooth Banach *** we show the following:(1) the universal inequality holds for all u^(*) ∈ X^(*);(2) the constant 5/2 can be reduced to 3/2 provided that Y~*is strictly convex;(3) the existence of such a g implies the existence of a phase isometryΘ:X→Y such that■ provided that Y^(**) has the w^(*)-Kadec-Klee property(for example,Y is both reflexive and locally uniformly convex).

关键词： ε-phase isometry phase isometry Banach space

黄河流域地区与长江经济带高质量发展的动能转换与策略重点比较

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资源科学 2024年第3期46卷 435-449页

作者：孙久文周孝伦中国人民大学应用经济学院北京100872

[目的]通过比较分析黄河流域地区和长江经济带新旧动能转换空间分布差异及其内在驱动机制,为新时代中国新旧动能转换和制定有针对性的区域协调发展政策提供参考。[方法]本文基于2021年地级及以上城市数据,从动力变革、体制改革、结构升... 详细信息

[目的]通过比较分析黄河流域地区和长江经济带新旧动能转换空间分布差异及其内在驱动机制,为新时代中国新旧动能转换和制定有针对性的区域协调发展政策提供参考。[方法]本文基于2021年地级及以上城市数据,从动力变革、体制改革、结构升级和发展转变等4个方面选取指标建立了新旧动能转换水平度量指标体系,比较分析了黄河流域地区与长江经济带新旧动能转换空间分布差异,并利用地理探测器分析新旧动能转换的主要影响因素。在比较分析的基础上,进一步讨论了两大区域高质量发展的策略重点。[结果](1)黄河流域地区新旧动能转换水平整体低于长江经济带,且内部空间差异显著,呈现“上、下游地区水平高,中游地区水平低”的局面,山东半岛城市群东部和西部以及兰州、西安、太原和郑州等省会城市新旧动能转换水平较高。长江经济带新旧动能转换水平总体上表现出“东高西低”的特征。(2)全局莫兰指数显示黄河流域地区新旧动能转换不存在显著的空间相关性,而长江经济带新旧动能转换存在显著的空间正相关关系。局部莫兰分析显示,黄河流域地区“高-高”集聚主要分布在山东半岛城市群东部城市,“低-低”集聚主要分布在关中平原城市群。长江经济带“高-高”集聚类型占比最大,主要分布在长三角城市群。(3)城市规模、消费能力和人力资本是黄河流域地区新旧动能转换的核心驱动因素,经济发展水平、城市规模、人力资本和对外开放水平对长江经济带新旧动能转换有显著促进作用。分城市群来看,经济发展水平、信息化水平和对外开放水平对黄河流域地区新旧动能转换的促进作用较弱,特别是关中平原、黄河几字弯和兰西等城市群。从东到西水资源量和环境规制对两大区域新旧动能转换水平的影响逐渐加强,尤其是黄河几字弯、兰西、滇中和黔中城市群等生态脆弱地区。此外,黄河流域地区中黄河几字弯和兰西城市群发展滞后,尚未形成有效的新旧动能转换机制。[结论]黄河流域地区与长江经济带新旧动能转换水平仍有较大的提升空间,需进一步发展新质生产力,推进产业结构转型升级,同时在推进信息化建设、提高对外开放水平等方面持续发力。此外,还应优化重大生产力布局,深入推进区域协调发展。

关键词：新旧动能转换空间差异地理探测器黄河流域长江经济带

Efficacy and safety of PD-1 blockade plus long-course chemoradiotherapy in locally advanced rectal cancer(NECTAR):a multi-center phase 2 study

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Signal Transduction and Targeted Therapy 2024年第4期9卷 1721-1729页

作者： Zhengyang Yang Jiale Gao Jianyong Zheng Jiagang Han Ang Li Gang Liu Yi sun Jie Zhang Guangyong Chen Rui Xu Xiao Zhang Yishan Liu Zhigang Bai Wei Deng Wei He Hongwei Yao Zhongtao Zhang Department of General Surgery Beijing Friendship HospitalCapital Medical UniversityState Key Lab of Digestive HealthNational Clinical Research Center for Digestive DiseasesBeijingChina Department of Gastrointestinal Surgery The First Affiliated Hospital of Air Force Medical UniversityXi'anChina Department of General Surgery Beijing Chaoyang HospitalCapital Medical UniversityBeijingChina Department of General Surgery Beijing Xuanwu HospitalCapital Medical UniversityBeijingChina Department of General Surgery Tianjin Medical University General HospitalTianjinChina Department of Anorectal Tianjin People's HospitalTianjinChina Department of Radiology Beijing Friendship Hospital Capital Medical UniversityBeijingChina Department of Pathology Beijing Friendship HospitalCapital Medical UniversityBeijingChina Department of Thoracic Surgery/institute of Thoracic Oncology West China HospitalSichuan UniversityChengduChina

Adding PD-1 blockade in the neoadjuvant regimens for locally advanced rectal cancer(LARC)patients with microsatellite stable(MsS)/mismatch repair-proficient(pMMR)tumors is an attractive,but debatable *** phase 2,multicenter,prospective,single-arm study enrolled patients from 6 centers from June 2021 to November *** advanced rectal cancer(LARC,cT_(3-4a)N_(0)M_(0) and cT_(1-4a)N_(1-2)M_(0))patients aged≥18 years with the distance from distal border of tumor to anal verge≤10 cm(identified by Magnetic Resonance imaging)were qualifed for *** patients received long-course radiotherapy(50 Gy/25 fractions,2 Gy/fraction,5 days/week)and three 21-day cycles capecitabine(850-1000 mg/m2,bid,po,day1-14)and three 21-day cycles tislelizumab(200 mg,***,day8)as *** mesorectal excision(TME)was 6-12 weeks after the end of radiotherapy to achieve radical resection.A total of 50 patients were enrolled in this *** pathological complete response rate was 40.0%[20/50,95%confidence interval(Ci):27.61-53.82%],while 15(30.0%,95%Ci:19.1-43.75%),9(18.0%,95%Ci:9.77-30.8%),2(4.0%,95%Ci:1.10-13.46%)patients respectively achieved grade 1,2,and 3 tumor ***-related adverse events(TRAEs)occurred in 28(56.0%)LARC patients,including 26(52.0%)with grade i-ii and 2(4.0%)with grade ii(1 with grade 3 immune-related colitis and 1 with grade 3 rash).PD-1 blockade plus long-course chemoradiotherapy(CRT)showed promising therapeutic effects according to pathological complete response rate and is well-tolerated in LARC patients.A larger randomized controlled study is desired to further validate the above findings.

关键词： rectal cancer phase

Loss of monopolar spindle-binding protein 3B expression promotes colorectal cancer malignant behaviors by activation of target of rapamycin kinase/autophagy signaling

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World Journal of Gastroenterology 2024年第26期30卷 3229-3246页

作者： Juan sun Jin-Xiu Zhang Meng-Shi Li Meng-Bin Qin Ruo-Xi Cheng Qing-Ru Wu Qiu-Ling Chen Dan Yang Cun Liao Shi-Quan Liu Jie-An Huang Department of Gastroenterology The Second Affiliated Hospital of Guangxi Medical UniversityNanning 530007Guangxi Zhuang Autonomous RegionChina Department of Colorectal&Anal Surgery The First Affiliated Hospital of Guangxi Medical UniversityNanning 530021Guangxi Zhuang Autonomous RegionChina

BACKGROUND Monopolar spindle-binding protein 3B(MOB3B)functions as a signal transducer and altered MOB3B expression is associated with the development of human *** To investigate the role of MOB3B in colorectal cancer(CRC).METHODS This study collected 102 CRC tissue samples for immunohistochemical detection of MOB3B expression for association with CRC *** overexpression and knockdown of MOB3B expression were induced in CRC cell lines,changes in cell viability,migration,invasion,and gene expression were *** cell autophagy was detected using transmission electron microscopy,while nude mouse xenograft experiments were performed to confirm the in-vitro *** MOB3B expression was reduced in CRC vs normal tissues and loss of MOB3B expression was associated with poor CRC *** of MOB3B protein in vitro attenuated the cell viability as well as the migration and invasion capacities of CRC cells,whereas knockdown of MOB3B expression had the opposite effects in CRC *** the molecular level,microtubule-associated protein light chain 3 ii/i expression was elevated,whereas the expression of matrix metalloproteinase(MMP)2,MMP9,sequestosome 1,and phosphorylated mechanistic target of rapamycin kinase(mTOR)was downregulated in MOB3B-overexpressing RKO *** contrast,the opposite results were observed in tumor cells with MOB3B *** nude mouse data confirmed these in-vitro findings,i.e.,MOB3B expression suppressed CRC cell xenograft growth,whereas knockdown of MOB3B expression promoted the growth of CRC cell *** Loss of MOB3B expression promotes CRC development and malignant behaviors,suggesting a potential tumor suppressive role of MOB3B in CRC by inhibition of mTOR/autophagy signaling.

关键词： Colorectal cancer Monopolar spindle-binding protein 3B Mechanistic target of rapamycin kinase Autophagy Prognosis