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内镜逆行性胆管胰管造影术治疗老年胆管结石伴胆管炎患者复发影响因素

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中外医药研究 2024年第17期3卷 78-80页

作者：庞学宇毕节市第三人民医院贵州毕节551799

目的:分析内镜逆行性胆管胰管造影术(ERCP)治疗老年胆管结石伴胆管炎患者复发影响因素。方法:选取2021年1月—2023年8月于毕节市第三人民医院行ERCP治疗的患者100例作为研究对象,在患者接受ERCP治疗后,对其进行随访,统计患者胆管炎复发... 详细信息

目的:分析内镜逆行性胆管胰管造影术(ERCP)治疗老年胆管结石伴胆管炎患者复发影响因素。方法:选取2021年1月—2023年8月于毕节市第三人民医院行ERCP治疗的患者100例作为研究对象,在患者接受ERCP治疗后,对其进行随访,统计患者胆管炎复发情况,将患者分为复发组与未复发组。比较不同复发情况下患者的临床资料,分析老年胆管炎患者在接受ERCP治疗后胆管炎复发的影响因素。结果:在患者经过治疗后随访中,出现胆管炎复发50例(50.00%)。复发组手术时间长于未复发组,憩室发生率、血清总胆红素(TBil)水平、血清碱性磷酸酶(ALP)水平、血清空腹血糖(FBG)水平、血清C反应蛋白(CRP)水平高于未复发组,十二指肠镜重复消毒率低于未复发组,差异有统计学意义(P<0.05)。治疗后胆管炎复发多元回归因素进行分析,手术时间、憩室(合并=1,未合并=0)、血清TBil水平、血清ALP水平、血清FBG水平、血清CRP水平等因素影响患者复发,差异有统计学意义(P<0.05)。结论:ERCP治疗老年胆管结石伴胆管炎的效果良好,但是实际治疗会受到患者年龄因素的影响,手术时间、十二指肠镜未重复消毒、血清TBil、ALP、CRP、FBG水平高是治疗后胆管炎反复发作的主要因素。

关键词：内镜逆行性胆管胰管造影术老年胆管结石伴胆管炎复发影响因素

Various admixtures to mitigate the long-term strength retrogression of Portland cement cured under high pressure and high temperature conditions

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Journal of Rock Mechanics and Geotechnical Engineering 2023年第1期15卷 191-203页

作者： Jiankun Qin xueyu pang Ashok Santra Guodong Cheng Hailong Li School of Petroleum Engineering China University of Petroleum(East China)Qingdao266580China Key Laboratory of Unconventional Oil&Gas Development(China University of Petroleum(East China)) Ministry of EducationQingdao266580China Drilling Technology Team Aramco Americas:Aramco Research Center16300 Park Row DriveHoustonTX77084USA

In order to investigate the problem of long-term strength retrogression in oil well cement systems exposed to high pressure and high temperature(HPHT)curing conditions,various influencing factors,including cement sources,particle sizes of silica flour,and additions of silica fume,alumina,colloidal iron oxide and nano-graphene,were *** simulate the environment of cementing geothermal wells and deep wells,cement slurries were directly cured at 50 MPa and 200?*** compositions(as determined by X-ray diffraction Rietveld refinement),water permeability,compressive strength and Young’s modulus were used to evaluate the qualities of the set ***-term curing(2e30 d)test results indicated that the adoption of 6 m m ultrafine crystalline silica played the most important role in stabilizing the mechanical properties of oil well cement systems,while the addition of silica fume had a detrimental effect on strength ***-term curing(2e180 d)test results indicated that nano-graphene could stabilize the Young’s modulus of oil well cement ***,none of the ad-mixtures studied here can completely prevent the strength retrogression phenomenon due to their inability to stop the conversion of amorphous to crystalline phases.

关键词： High pressure and high temperature(HPHT) Strength retrogression Young’s modulus Water permeability Rietveld method

Asynchronous gain-scheduled control of deepwater drilling riser system with hybrid event-triggered sampling and unreliable communication

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Frontiers of Information Technology & Electronic Engineering 2024年第2期25卷 272-285页

作者： Na pang Dawei ZHANG Shuqian ZHU School of Mathematics Shandong UniversityJinan250100China

This paper investigates the recoil control of the deepwater drilling riser system with nonlinear tension force and energy-bounded friction force under the circumstances of limited network resources and unreliable *** from the existing linearization modeling method,a triangle-based polytope modeling method is applied to the nonlinear riser *** on the polytope model,to improve resource utilization and accommodate random data loss and communication delay,an asynchronous gain-scheduled control strategy under a hybrid event-triggered scheme is *** asynchronous linear parameter-varying system that blends input delay and impulsive update equation is presented to model the nonlinear networked recoil control system,where the asynchronous deviation bounds of scheduling parameters are *** to the Lyapunov-Krasovskii functional method,some solvable conditions of disturbance attenuation analysis and recoil control design are derived such that the resulting networked system is exponentially mean-square stable with prescribed H∞*** obtained numerical results verified that the proposed nonlinear networked control method can achieve a better recoil response of the riser system with less transmission data compared with the linear control method.

关键词： Riser system Recoil control Asynchronous gain-scheduled control Data loss Event-triggered scheme

Compositional evolution for mixed aerosols containing gluconic acid and typical nitrate and the effect of multiply factors on hygroscopicity

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Journal of Environmental Sciences 2024年第5期139卷 206-216页

作者： Yue Zhu Shufeng pang Yunhong Zhang School of Chemistry and Chemical Engineering Beijing Institute of TechnologyBeijing 100081China

The aging process of atmospheric aerosols usually leads to a mixture of inorganic salts and organic compounds of anthropogenic *** organic compounds,polyhydroxy organic acids are important components,however,the study on composition and hygroscopic properties of the mixture containing inorganics and polyhydroxy organic acids is *** this study,gluconic acid,the proxy of polyhydroxy organic acids,is mixed with the representative nitrate(Mg(NO_(3))_(2),Ca(NO_(3))_(2))to form ***-FTIR and optical microscopy are employed to study the component changes and hygroscopicity as a function of relative *** relative humidity fluctuates,the FTIR-ATR spectra display that the internal mixed gluconic acid(CH_(2)(CH)_(4)(OH)_(5)COOH)and nitrate can react to release acidic gases,forming relevant gluconate and further affecting the *** specific presentation is particles cannot be recovered to their original size after the dehydration-hydration process and there will be some disparities in GF for mixed *** the gluconic acid-Ca(NO_(3))_(2)/Mg(NO_(3))_(2)mixtures with molar ratios of 1:1,higher degree of reaction resulting in the production of large amounts of gluconate should be responsible to the lower hygroscopicity compared to ZSR *** 1:2 gluconic acid-nitrate mixed systems(with higher nitrate content),the hygroscopicity of mixtures are higher than the ZSR prediction.A possible reason could be‘salt-promoting effect’on the organic fractions of the surplus inorganic salt in the *** data can improve the chemical composition list evaluation,in turn hygroscopic properties and phase state of atmospheric aerosol,and then the climate effect.

关键词： Hygroscopicity Gluconic acid Reaction ZSR simulation Size growth factors

Ionic liquid-assisted preparation of hydroxyapatite and its catalytic performance for decarboxylation of itaconic acid

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Chinese Journal of Chemical Engineering 2024年第3期67卷 9-15页

作者： Shutong pang Hualiang An Xinqiang Zhao Yanji Wang Hebei Provincial Key Laboratory of Green Chemical Technology and Efficient Energy Saving Tianjin Key Laboratory of Chemical Process SafetySchool of Chemical Engineering and TechnologyHebei University of TechnologyTianjin 300130China

The synthesis of methacrylic acid from biomass-derived itaconic acid is a green route,for it can get rid of the dependence on fossil *** order to solve the problems on this route such as use of a preciousmetal catalyst and a corrosive homogeneous alkali,we prepared a series of hydroxyapatite catalysts by an ionic liquid-assisted hydrothermal method and evaluated their catalytic *** results showed that the ionic liquid[Bmim]BF_(4) can affect the crystal growth of hydroxyapatite,provide fluoride ion for fluorination of hydroxyapatite,and adjust the surface acidity and basicity,morphology,textural properties,crystallinity,and composition of ***[Bmim]BF4 dosage and hydrothermal temperature can affect the fluoride ion concentration in the hydrothermal system,thus changing the degree of fluoridation of *** fluoride-ion concentration can lead to the formation of CaF_(2) and thus significantly decrease the catalytic performance of *** hydrothermal time mainly affects the growth of hydroxyapatite crystals on the c axis,leading to different catalytic *** suitable conditions for the preparation of this fluoridized hydroxyapatite are as follows:a mass ratio of[Bmim]BF4 to calcium salt=0.2:1,a hydrothermal time of 12 h,and a hydrothermal temperature of 130℃.A maximal methacrylic acid yield of 54.7%was obtained using the fluoridized hydroxyapatite under relatively mild reaction conditions(250℃ and 2 MPa of N_(2))in the absence of a precious-metal catalyst and a corrosive homogeneous alkali.

关键词： Ionic liquid Hydroxyapatite Itaconic acid Methacrylic Decarboxylation reaction

Commentary:brain endothelial GSDMD as a novel target for brain disorders associated with BBB damage

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Chinese Journal of Natural Medicines 2024年第7期22卷 580-581页

作者： LIU Kui pang Tao State Key Laboratory of Natural Medicines New Drug Screening and Pharmacodynamics Evaluation CenterChina Pharmaceutical UniversityNanjing 210009China

The blood-brain barrier(BBB)is a highly selective and critical interface between the blood and the central nervous system(CNS),essential for maintaining the microenvironment necessary for normal brain function and homeostasis[1].The BBB is primarily formed by brain endothelial cells(bECs),pericytes,and astrocytes,and it operates in concert with microglia/macrophages and neurons[2,3]to constitute the neurovascular unit(Fig.1).Disruption of the BBB or the presence of systemic inflammation can precipitate or exacerbate various CNS pathologies,including Alzheimer’s disease[4],amyotrophic lateral sclerosis[5],Huntington’s disease[6]and multiple sclerosis.

关键词： Brain endothelial cells GSDMD Blood-brain barrier Natural products Neuroinflammation Brain disorders

Rational Design of Capping Ligands of Quantum Dots for Biosensing

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Chemical Research in Chinese Universities 2024年第2期40卷 162-172页

作者： XU Xinran LIU An-an pang Daiwen State Key Laboratory of Medicinal Chemical Biology Tianjin Key Laboratory of Biosensing and Molecular RecognitionResearch Center for Analytical SciencesCollege of ChemistryNankai UniversityTianjin300071P.R.China

Quantum dots have been widely applied in biosensing due to their outstanding optical *** emissions of quantum dots are mainly determined by their composition and size,as described by the Brus’s ***,in this case,their emissions are hardly regulated reversibly and responsively,which are unsuitable for biosensing and *** the last decade,capping ligands have been used for designing biosensors because of their responsive regulation on the photoluminescence of quantum ***,we first summarize the advances in characterization and calculation specific for ligands,which have helped to provide insights into the photoluminescence process and energy band theory of quantum *** then review two ways of ligand design that influence the optical properties of quantum dots:affecting the process of photoluminescence,or the orbital/electronic *** the latter case,the atoms on both the ligand and the surface of the quantum dot interact to affect the energy band structure of the quantum dot *** are presented of how these quantum dots that possess responsive properties due to the design of the ligands have been applied to *** further exploration,we hope to see advances in the fundamental understanding of the energy band structures and practical applications of these quantum dots.

关键词： Quantum dot Ligand Photoluminescence Responsiveness Sensor

Slip distribution inversion of seismic sub-fault dip iteration using gradient based optimizer algorithm

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Geodesy and Geodynamics 2024年第2期15卷 114-121页

作者： Leyang Wang Han Li Ming pang Key Laboratory of Mine Environmental Monitoring and Improving Around Poyang Lake of Ministry of Natural Resources East China University of TechnologyNanchang 330013China School of Surveying and Geoinformation Engineering East China University of TechnologyNanchang 330013China College of Resources and Environment Shandong Agricultural UniversityTaian 271018China

This paper considers setting different dips for different sub-faults to fit the actual rupture situation based on the fault rupture of the 2013 Lushan M_(S)7.0 ***,combined with the coseismic GNSS data of the Lushan earthquake,the source parameters and sliding distribution of the Lushan earthquake fault are ***,we use the gradient based optimizer(GBO)in nonlinear inversion to obtain the source parameters of this seismic *** inversion results indicate that the strike of the fault is 206.52°,the dip is 44.10°,the length is 21.92 km,and the depth is 12.79 *** refine the sliding distribution of the seismic fault,the seismic fault is divided into 3×3 ***,we fix the central sub-fault dip of 44.10°;the dip of other sub-faults is obtained by *** that,the model is further divided into a fault layer model composed of 23×19 sub fault slices,and using the Matlab fitting function is used to fit the dip of the 23×19 sub ***,the Lushan seismic fault plane is established as a shovel structure with steep upper and gentle lower,steep south and gentle *** slip distribution inversion results indicate that the depth of the slip peak is 13 km,the corresponding maximum slip momentum is 0.67 m,the seismic moment is 1.10×10^(19)N·m and the corresponding moment magnitude is *** results above are consistent with the research results of seismology.

关键词： Gradient basedoptimizer(GBO) Lushan earthquake Non-planefault model Slid distribution

Study on a conical bearing for acceleration-sensitive equipment

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Earthquake Engineering and Engineering Vibration 2024年第1期23卷 103-128页

作者： pang Hui Xu Wen Dai Junwu Jiang Tao Key Laboratory of Earthquake Engineering and Engineering Vibration Institute of Engineering MechanicsChina Earthquake AdministrationHarbin 150080China Key Laboratory of Earthquake Disaster Mitigation Ministry of Emergency ManagementHarbin 150080China School of Civil Engineering and Transportation Beihua UniversityJilin 132013China

Seismic isolation effectively reduces seismic demands on building structures by isolating the superstructure from ground vibrations during ***,isolation strategies give less attention to acceleration-sensitive systems or ***,as the isolation layer’s displacement grows,the stiffness and frequency of traditional rolling and sliding isolation bearings increases,potentially causing self-centering and resonance *** a result,a new conical pendulum bearing has been selected for acceleration-sensitive equipment to increase self-centering capacity,and additional viscous dampers are incorporated to enhance system ***,the theoretical formula for conical pendulum bearings is supplied to analyze the device’s dynamic parameters,and shake table experiments are used to determine the proposed device’s isolation efficiency under various *** to the test results,the newly proposed devices have remarkable isolation performance in terms of minimizing both acceleration and displacement ***,a numerical model of the isolation system is provided for further research,and the accuracy is demonstrated by the aforementioned experiments.

关键词： seismic isolation acceleration-sensitive equipment the conical pendulum bearing shake table tests isolation performance,numerical model