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Experimental Study of Temperature Control Based on Composite Phase Change Materials during Charging and Discharging of Battery

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Journal of Thermal Science 2024年第2期33卷 578-590页

作者： LI Xiaolin wang Jun CAO Wenxiang ZHANG xuesong School of Automotive and Traffic Engineering Jiangsu UniversityZhenjiang212013China

This study is to utilize the heat-absorbing and releasing capabilities of phase change materials(PCM)to regulate the surface temperature fluctuations of batteries during charging and discharging.The goal is to keep the battery within the optimal operating temperature range.The impact of PCM thickness and phase change temperature on battery temperature is investigated by encircling a cylindrical battery with a PCM ring.To improve the thermal conductivity of PCM,expanded graphite(EG) is added to make a composite phase change material(CPCM),and the effects of various EG mass ratios on battery surface temperature and CPCM utilization level are investigated.The findings indicate that increasing PCM thickness effectively extends temperature control time,but its impact is limited.The difference in phase change temperature of PCM controls the battery temperature in different temperature ranges.Lower phase change temperatures are unsuitable for controlling battery temperature in high temperature environments.The addition of EG enhances the thermal conductivity of PCM,leading to further control of battery temperature.The results show that the addition of 6%(mass ratio) EG to CPCM extends the effective temperature control time by 11 min and improves by 28% compared to a single PCM.The CPCM utilization is also more satisfactory and achieved a balance between heat storage and thermal conductivity in a battery thermal management system(BTMS) based on PCM.

关键词： phase change material expanded graphite thermal management system effective control time

Femtosecond laser fabrication of 3D vertically aligned micro-pore network on thick-film Li4Ti5O12 electrode for high-performance lithium storage

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Journal of Energy Chemistry 2024年第8期95卷 250-262页

作者： Quansheng Li Xiaofei Sun xuesong Mei Lingzhi wang Minxing Yang Jianlei Cui Wenjun wang State Key Laboratory for Manufacturing System Engineering Xi'an Jiaotong University Shaanxi Key Laboratory of Intelligent Robots Xi'an Jiaotong University School of Mechanical Engineering Xi'an Jiaotong University

The development of energy storage devices with high energy density relies heavily on thick film electrodes, but it is challenging due to the limited ion transport kinetics inherent in thick electrodes. Here,we report on the preparation of a directional vertical array of micro-porous transport networks on LTO electrodes using a femtosecond laser processing strategy, enabling directional ion rapid transport and achieving good electrochemical performance in thick film electrodes. Various three-dimensional(3D)vertically aligned micro-pore networks are innovatively designed, and the structure, kinetics characteristics, and electrochemical performance of the prepared ion transport channels are analyzed and discussed by multiple characterization and testing methods. Furthermore, the rational mechanisms of electrode performance improvement are studied experimentally and simulated from two aspects of structural mechanics and transmission kinetics. The ion diffusion coefficient, rate performance at 60 C,and electrode interface area of the laser-optimized 60-15% micro-porous transport network electrodes increase by 25.2 times, 2.2 times, and 2.15 times, respectively than those of untreated electrodes.Therefore, the preparation of 3D micro-porous transport networks by femtosecond laser on ultra-thick electrodes is a feasible way to develop high-energy batteries. In addition, the unique micro-porous transport network structure can be widely extended to design and explore other high-performance energy materials.

关键词： Femtosecond laser Ion transport kinetics Laser processing Micro-porous transport networks Thick film electrodes

Bivariate macro-level safety analysis of non-motorized vehicle crashes and crash-involved road users

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Journal of Traffic and Transportation Engineering(English Edition) 2022年第6期9卷 978-990页

作者： Zhicheng Dai xuesong wang School of Transportation Engineering Tongji UniversityShanghai 201804China The Key Laboratory of Road and Traffic Engineering Ministry of EducationShanghai 201804China

The high risk of injury resulting from non-motorized vehicle(NMV)crashes has created the goal of using the 3E strategy to comprehensively improve NMV safety.Traditional safety improvement methods identify hot zones generally by crash frequency or density,which is effective for roadway engineering improvements but neglects characteristics related to other improvements such as safety education.As safety education would be more effective if targeted at the residences of crash-involved road users,the traditional approach to hot zones may therefore provide biased results for such alternative countermeasures.After confirming that 77.17%of NMV crashes occurred outside the involved riders’areas of residence,this study compared the differences between the locations of crashes and the residences of NMV crash-involved riders in safety influencing factors and hot zone identification.A Poisson lognormal bivariate conditional autoregressive(PLN-BCAR)model was developed to account for potential correlations between crashes and involved riders.The model was compared with the univariate Poisson lognormal conditional autoregressive(UPLN-CAR)model and the bivariate Poisson lognormal conditional autoregressive(BPLNCAR)model;the PLN-BCAR model outperformed the other two models in its better interpretation of the influencing factors and its more efficient parameter estimation.Model results indicated that crashes were mainly associated with roadway and land use characteristics,while involved road users were mainly associated with socioeconomic and land use characteristics.The potential for safety improvement method was adopted to identify hot zones for countermeasure implementation.Results showed over 60%of the identified hot zones were inconsistent:they needed improvement in either engineering or education but not both.These findings can help target the type of improvement to better utilize resources for NMV safety.

关键词： Macro safety analysis Hot zone identification Non-motorized vehicle safety Bivariate spatial model Potential for safety improvement

Process in laser drilling of deep microholes without taper on metal materials

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Science China(Technological Sciences) 2024年第1期67卷 37-59页

作者： FAN RunZe MEI xuesong CUI JianLei State Key Laboratory for Manufacturing Systems Engineering Xi’an Jiaotong UniversityXi’an 710054China

Deep microhole machining is currently a prominent research area within the aerospace field,encompassing blade film cooling and fuel injection control technologies.However,taper defects in metal materials may lead to performance degradation or even structural damage over a component’s lifetime.Trepanning and helical drilling,facilitated by ultrashort pulse lasers,have proven more suitable for achieving high-precision,deep holes in metal materials.Nonetheless,excessive repetition rates can also result in severe thermal damage.Various methods are commonly employed for controlling taper,including parameter optimization,assistance,and secondary modification.Tilted laser beam drilling is widely utilized and has been integrated into relevant machining systems for commercial applications.Typical deep microholes include film cooling holes and injection microholes.Laser drilling is a potential machining method for new materials in the aerospace field.Although laser drilling processing has been studied,numerous related scientific challenges and technical difficulties must be addressed before practical implementation.

关键词： aerospace laser drilling deep microhole taper control

Breeding exceptionally fragrant soybeans for soy milk with strong aroma

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Journal of Integrative Plant Biology 2024年第4期66卷 642-644页

作者： Hongtao Xie Minglei Song xuesong Cao Qingfeng Niu Jianhua Zhu Shasha Li Xin wang Xiaomu Niu Jian-Kang Zhu Bellagen Biotechnology Co.Ltd. Jinan 250000China Institute of Advanced Biotechnology and School of Life Sciences Southern University of Science and TechnologyShenzhen 518055China School of Life Sciences Anhui Agricultural UniversityHefei 230036China Shandong Normal University Jinan 250000China

Soybean(Glycine max(L.)Merr.)is a major source of vegetable protein and oil in human diet and animal nutrition.Soybean seeds have been extensively used in various food products and snacks.Taste quality,particularly the aroma,affects cooking and eating,and ultimately influences consumer preference.Soy milk is particularly popular in China and has been gaining popularity in many other countries in the world.

关键词： exceptional soybean cooking

3D-bioprinted anisotropic bicellular living hydrogels boost osteochondral regeneration via reconstruction of cartilage–bone interface

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The Innovation 2024年第1期5卷 88-97页

作者： Yijian Zhang Duo Li Yang Liu Liuqi Peng Dongdong Lu Pinpin wang Dongxu Ke Huilin Yang xuesong Zhu Changshun Ruan Department of Orthopaedics The First Affiliated Hospital of Soochow UniversitySoochow UniversitySuzhou 215006China Research Center for Human Tissue and Organ Degeneration Institute of Biomedicine and BiotechnologyShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China University of Chinese Academy of Sciences Beijing 100049China Novaprint Therapeutics Suzhou Co. Ltd.Room 605B1 BuildingBioBayNo.218 Xinghu StreetSuzhou Industrial ParkSuzhou 215000China

Reconstruction of osteochondral(OC)defects represents an immense challenge due to the need for synchronous regeneration of special stratified tissues.The revolutionary innovation of bioprinting provides a robust method for precise fabrication of tissue-engineered OCs with hierarchical structure;however,their spatial living cues for simultaneous fulfilment of osteogenesis and chondrogenesis to reconstruct the cartilage-bone interface of OC are underappreciated.Here,inspired by natural OC bilayer features,anisotropic bicellular living hydrogels(ABLHs)simultaneously embedding articular cartilage progenitor cells(ACPCs)and bone mesenchymal stem cells(BMSCs)in stratified layers were precisely fabricated via two-channel extrusion bioprinting.The optimum formulation of the 7%GelMA/3%AlgMA hydrogel bioink was demonstrated,with excellent printability at room temperature and maintained high cell viability.Moreover,the chondrogenic ability of ACPCs and the osteogenic ability of BMSCs were demonstrated in vitro,confirming the inherent differential spatial regulation of ABLHs.

关键词： printing stratified boost

Targeted G-to-T base editing for generation of novel herbicide-resistance gene alleles in rice

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Journal of Integrative Plant Biology 2024年第6期66卷 1048-1051页

作者： Yifu Tian Xinbo Li Jiyong Xie Zai Zheng Rundong Shen xuesong Cao Mugui wang Chao Dong Jian-Kang Zhu Ministry of Agriculture and Rural Affairs Key Laboratory of Gene Editing Technologies (Hainan) Institute of Crop Sciences and National Nanfan Research Institute Chinese Academy of Agricultural Sciences Hainan Seed Industry Laboratory Shanghai Center for Plant Stress Biology CAS Center for Excellence in Molecular Plant Sciences The Chinese Academy of Sciences University of Chinese Academy of Sciences Institute of Advanced Biotechnology and School of Medicine Southern University of Science and Technology

Deaminase-based cytosine base editors (CBEs) and adenine base editors (ABEs) induce C-to-T and A-to-G transitions, respectively, enabling single-nucleotide variants(SNVs) in plants for research and crop enhancement (Li et al.,2023a). The C-to-G base editors (CGBEs) and A-to-Y base editors (AYBEs), developed by incorporating glycosylases with CBEs and ABEs, expand the repertoire of base editing products, allowing C-to-T/G and A-to-T/G transversions in plants (Li et al., 2023b, 2023c; Sretenovic et a., 2021;

关键词： TOLERANCE

Trogocytosis of CAR molecule regulates CAR-T cell dysfunction and tumor antigen escape

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Signal Transduction and Targeted Therapy 2024年第1期9卷 326-337页

作者： You Zhai Yicong Du Guanzhang Li Mingchen Yu Huimin Hu Changqing Pan Di wang Zhongfang Shi Xu Yan xuesong Li Tao Jiang Wei Zhang Department of Molecular Neuropathology Beijing Neurosurgical InstituteCapital Medical UniversityBeijingPR China Department of Neurosurgery Beijing Tiantan HospitalCapital Medical UniversityBeijingPR China Department of Urology Peking University First HospitalInstitute of UrologyPeking UniversityNational Urological Cancer CenterBeijingPR China Department of Pathophysiology Beijing Neurosurgical InstituteCapital Medical UniversityBeijingPR China China National Clinical Research Center for Neurological Diseases BeijingPR China Center of Brain Tumor Beijing Institute for Brain DisordersBeijingPR China Research Unit of Accurate Diagnosis Treatmentand Translational Medicine of Brain TumorsChinese Academy of Medical SciencesBeijingPR China Chinese Glioma Genome Atlas Network(CGGA)and Asian Glioma Genome Atlas Network(AGGA) BeijingPR China

Chimeric antigen receptor(CAR)T-cell therapy has demonstrated clinical response in treating both hematologic malignancies and solid tumors.Although instances of rapid tumor remissions have been observed in animal models and clinical trials,tumor relapses occur with multiple therapeutic resistance mechanisms.Furthermore,while the mechanisms underlying the long-term therapeutic resistance are well-known,short-term adaptation remains less understood.However,more views shed light on short-term adaptation and hold that it provides an opportunity window for long-term resistance.In this study,we explore a previously unreported mechanism in which tumor cells employ trogocytosis to acquire CAR molecules from CAR-T cells,a reversal of previously documented processes.This mechanism results in the depletion of CAR molecules and subsequent CAR-T cell dysfunction,also leading to short-term antigen loss and antigen masking.Such type of intercellular communication is independent of CAR downstream signaling,CAR-T cell condition,target antigen,and tumor cell type.However,it is mainly dependent on antigen density and CAR sensitivity,and is associated with tumor cell cholesterol metabolism.Partial mitigation of this trogocytosis-induced CAR molecule transfer can be achieved by adaptively administering CAR-T cells with antigen density-individualized CAR sensitivities.Together,our study reveals a dynamic process of CAR molecule transfer and refining the framework of clinical CAR-T therapy for solid tumors.

关键词： Together instance depletion

Determining the in vitro Anti-Aging Effect of the Characteristic Components from Eucommia ulmoides

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Journal of Renewable Materials 2022年第12期10卷 3131-3145页

作者： xuesong wang Zhihong wang Qiuling Yang Sheng Peng Mijun Peng Guangdong Provincial Key Laboratory of Chemical Measurement and Emergency Test Technology Guangdong Provincial Engineering Research Center for Ambient Mass SpectrometryInstitute of AnalysisGuangdong Academy of Sciences(China National Analytical CenterGuangzhou)Guangzhou510070China Guangdong Provincial Key Laboratory of Silviculture Protection and UtilizationGuangdong Academy of ForestryGuangzhou510520China National&Local United Engineering Laboratory of Integrative Utilization Technology of Eucommia ulmoides Jishou University Jishou427000China

To evaluate the potential anti-aging ability of Eucommia ulmoides,four characteristic components(chlorogenic acid,geniposidic acid,aucubin,quercetin)were selected to assess their effects on H_(2)O_(2)-induced oxidative damage model of human umbilical vein endothelial cell(HUVEC).Oxidative damage indexes,inflammatory factors,cell cycle,cell apoptosis,cell senescence,and their related proteins were analyzed by methyl thiazolyl tetrazolium(MTT)assay,enzyme-linked immunosorbent assay(ELISA),propidium iodide(PI)staining,annexin V-FITC/PI double staining,SAβ-galactosidase staining,and western blotting(WB).The results showed that H_(2)O_(2)-induced cell growth inhibition rate decreased as supplementation with characteristic components when compared to H_(2)O_(2) group.Meanwhile,the contents of antioxidant indexes(reactive oxygen species,lactate dehydrogenase,molondialdehyde,superoxide dismutase,glutathione),inflammatory factors(nuclear factor kappa-B,intercellular cell adhesion molecule-1,vascular cell adhesion protein 1),and functional factors(NO,Endothelin-1)in characteristic components treated groups improved if comparison with H_(2)O_(2) group,suggesting the characteristic components of E.ulmoides could alleviate H_(2)O_(2)-induced oxidative damage.Moreover,cell cycle,cell apoptosis,cell senescence,and their related proteins under characteristic components treatment exhibited a better effect than under H_(2)O_(2) treatment,implying the characteristic components could participate in anti-aging via multiple pathways.These results manifested that the characteristic components of E.ulmoides posses the capacity of anti-aging,which provided a basis for investigating the anti-aging ability of E.ulmoides itself.

关键词： Anti-aging Eucommia ulmoides characteristic components oxidative damage cell senescence