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小螺距滚柱牙型非接触式检测与偏差评价方法

重庆大学学报 2023年第3期46卷 45-57页

作者：徐洪伟魏沛堂周鹏亮杜雪松重庆大学机械传动国家重点实验室重庆400044 贵州群建精密机械有限公司贵州遵义563099

行星滚柱丝杠副(planetary roller screw mechanism, PRSM)是旋转运动与直线运动相互转化的新型重载精密传动装置,螺纹牙型加工质量直接决定其传动精度和承载性能。针对小螺距PRSM滚柱牙型非完整短圆弧检测评价的难题,利用高精度三坐标... 详细信息

行星滚柱丝杠副(planetary roller screw mechanism, PRSM)是旋转运动与直线运动相互转化的新型重载精密传动装置,螺纹牙型加工质量直接决定其传动精度和承载性能。针对小螺距PRSM滚柱牙型非完整短圆弧检测评价的难题,利用高精度三坐标测量机对滚柱轴向截面牙型非接触式检测,提出了基于非线性内点算法的滚柱牙型曲线拟合方法,验证了滚柱牙型曲线的拟合精度;建立了滚柱螺纹牙型偏差评价模型和偏差评价方法,绘制了基于本偏差模型的牙型偏差评价图,分析并总结了滚柱牙型偏差分布规律。提出的小螺距PRSM滚柱牙型检测评价方法,拟合残差平方和达到1.5×10~(-4)数级,牙型半径拟合精度控制在6μm,牙型圆心z_0坐标拟合精度控制在9.8μm,能够定量评判滚柱牙型形状精度和位置精度,在工程实际中具有可行性。

关键词：行星滚柱丝杠副非接触式检测非线性内点算法拟合精度滚柱牙型偏差

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Yuzaoea gen. nov., a new biraphid diatom(Bacillariophyceae)genus and its phylogenetic significance

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Acta Oceanologica Sinica 2024年第2期43卷 130-136页

作者： Honghan Liu Chenhong Li Lang Li xuesong Li Lin Sun Junrong Liang Jun Zhang Yahui Gao Changping Chen Key Laboratory of Ministry of Education for Coastal and Wetland Ecosystems and School of Life Sciences Xiamen UniversityXiamen 361102China State Key Laboratory of Marine Environmental Science Xiamen UniversityXiamen 361102China Guangxi Key Laboratory of Marine Environmental Science Guangxi Academy of Marine SciencesGuangxi Academy of SciencesNanning 530007China Beibu Gulf Marine Industry Research Institute Fangchenggang 538000China

The flexed frustules in pennate diatoms are usually associated with monoraphid diatoms. Interestingly, we found a biraphid diatom species with flexed frustules in an offshore intertidal beach environment on Weizhou Island,Beihai City, Guangxi Zhuang Autonomous Region, China. Therefore, based on morphological characteristics, we described a new genus of diatoms Yuzaoea sinensis gen. et sp. nov. CH Li, HH Liu, YH Gao & CP Chen. The frustule of this genus is characterized by heterogeneous frustule with one concave valve and one convex valve,complete raphe on both valves, straight and moderately eccentric raphe, uniseriate striae and girdle bands with a single row of areolae. The most identifying feature of this genus was the flexed frustule, which is rare in biraphid diatoms and common in monoraphid diatoms. We compared the morphometric characteristics of genus Yuzaoea with genus Rhoikoneis and several genera within the family Rhoicospheniaceae, including Rhoicosphenia,Campylopyxis, and Cuneolus. Phylogenetic analyses based on SSU rRNA and rbc L showed that the genus Yuzaoea was the sister group to the clade of Rhoicosphenia with a high support value(bootstrap values = 100%), and the clade “Yuzaoea+Rhoicosphenia” was sister to the clade of monoraphid diatoms, in which the genera Achnanthidium, Planothidium and some Cocconeis with high support values(bootstrap = 100%).Morphologically, the genus Yuzaoea shares many morphological features with monoraphid diatoms like genera Achnanthidium and Planothidium and the members within the Rhoicospheniaceae. Therefore, based on a combined morphological studies and phylogenetic results we suggested that this branch may represented the evolution of one kind monoraphid diatoms, from biraphid diatoms(e.g. genus Yuzaoea), to incompleted biraphid diatoms(e.g. genera Rhoicosphenia, Campylopyxis), to monoraphid diatoms(e.g. genera Achnanthidium and Planothidium).

关键词： biraphid diatom marine new genus Rhoicospheniaceae taxonomy Yuzaoea

Irisin-loaded electrospun core-shell nanofibers as calvarial periosteum accelerate vascularized bone regeneration by activating the mitochondrial SIRT3 pathway

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Regenerative Biomaterials 2024年第1期3卷 44-57页

作者： Xi Hua Mingzhuang Hou Lei Deng Nanning Lv Yong Xu xuesong Zhu Huilin Yang Qin Shi Hao Liu Fan He Department of Orthopaedics The First Affiliated Hospital of Soochow UniversitySoochow UniversitySuzhou 215006China Orthopaedic Institute Suzhou Medical CollegeSoochow UniversitySuzhou 215000China Department of Orthopedics Suzhou Wuzhong People’s HospitalSuzhouJiangsu Province 215128China Department of Orthopedic Surgery Lianyungang Clinical College of Xuzhou Medical UniversityLianyungang 222003China

The scarcity of native periosteum poses a significant clinical barrier in the repair of critical-sized bone *** challenge of enhancing regenerative potential in bone healing is further compounded by oxidative stress at the fracture ***,the introduction of artificial periosteum has demonstrated its ability to promote bone regeneration through the provision of appropriate mechanical support and controlled release of proosteogenic *** this study,a poly(L-lactic acid)(PLLA)/hyaluronic acid(HA)-based nanofibrous membrane was fabricated using the coaxial electrospinning *** incorporation of irisin into the core-shell structure of PLLA/HA nanofibers(PLLA/HA@Irisin)achieved its sustained *** vitro experiments demonstrated that the PLLA/HA@Irisin membranes exhibited favorable *** osteogenic differentiation of bone marrow mesenchymal stem cells(BMMSCs)was improved by PLLA/HA@Irisin,as evidenced by a significant increase in alkaline phosphatase activity and matrix ***,PLLA/HA@Irisin significantly enhanced the mitochondrial function of BMMSCs via the activation of the sirtuin 3 antioxidant *** assess the therapeutic effectiveness,PLLA/HA@Irisin membranes were implanted in situ into critical-sized calvarial defects in *** results at 4 and 8 weeks post-surgery indicated that the implantation of PLLA/HA@Irisin exhibited superior efficacy in promoting vascularized bone formation,as demonstrated by the enhancement of bone matrix synthesis and the development of new blood *** results of our study indicate that the electrospun PLLA/HA@Irisin nanofibers possess characteristics of a biomimetic periosteum,showing potential for effectively treating critical-sized bone defects by improving the mitochondrial function and maintaining redox homeostasis of BMMSCs.

关键词： periosteum irisin mitochondrial function critical-sized bone defect redox homeostasis

基于误差补偿的RV减速器摆线齿廓二次共轭修形方法

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中南大学学报（自然科学版） 2023年第11期54卷 4349-4358页

作者：杜雪松刘思奇李昌斌魏沛堂宋海蓝重庆大学高端装备机械传动全国重点实验室重庆400044

提出一种可以对加工误差进行补偿的RV减速器摆线齿廓二次共轭修形方法,通过建立的误差补偿模型,确定一次修形量,得到理论零侧隙摆线齿廓;再以给定的径向间隙、回差作为约束条件,通过建立的共轭齿廓优化模型确定二次修形量,得到共轭摆线... 详细信息

提出一种可以对加工误差进行补偿的RV减速器摆线齿廓二次共轭修形方法,通过建立的误差补偿模型,确定一次修形量,得到理论零侧隙摆线齿廓;再以给定的径向间隙、回差作为约束条件,通过建立的共轭齿廓优化模型确定二次修形量,得到共轭摆线齿廓。研究结果表明:该方法在单误差及组合误差条件下,均可对零件误差进行合理补偿,所确定的共轭齿廓在不发生装配干涉和保证传动精度的条件下,能改善齿面受力情况,降低摆线轮最大接触应力。该方法可应用于RV减速器的设计和装配阶段,降低零件加工难度和成本,具有重要的工程应用价值。

关键词： RV减速器摆线针轮齿廓修形误差补偿二次修形

Defects evolution in n-type 4H-SiC induced by electron irradiation and annealing

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Journal of Semiconductors 2024年第7期45卷 77-83页

作者： Huifan Xiong xuesong Lu Xu Gao Yuchao Yan Shuai Liu Lihui Song Deren Yang Xiaodong Pi State Key Laboratory of Silicon and Advanced Semiconductor Materials&School of Materials Science and Engineering Zhejiang UniversityHangzhou 310027China Key Laboratory of Power Semiconductor Materials and Devices of Zhejiang Province&Institute of Advanced Semiconductors ZJU-Hangzhou Global Scientific and Technological Innovation CenterZhejiang UniversityHangzhou 311200China

Radiation damage produced in 4H-SiC by electrons of different doses is presented by using multiple characterization techniques. Raman spectra results indicate that SiC crystal structures are essentially impervious to 10 Me V electron irradiation with doses up to 3000 kGy. However, irradiation indeed leads to the generation of various defects, which are evaluated through photoluminescence(PL) and deep level transient spectroscopy(DLTS). The PL spectra feature a prominent broad band centered at 500 nm, accompanied by several smaller peaks ranging from 660 to 808 nm. The intensity of each PL peak demonstrates a linear correlation with the irradiation dose, indicating a proportional increase in defect concentration during irradiation. The DLTS spectra reveal several thermally unstable and stable defects that exhibit similarities at low irradiation ***, after irradiating at the higher dose of 1000 kGy, a new stable defect labeled as R_(2)(Ec-0.51 eV) appeared after annealing at 800 K. Furthermore, the impact of irradiation-induced defects on SiC junction barrier Schottky diodes is discussed. It is observed that high-dose electron irradiation converts SiC n-epilayers to semi-insulating layers. However, subjecting the samples to a temperature of only 800 K results in a significant reduction in resistance due to the annealing out of unstable defects.

关键词： 4H-SiC deep level transient spectroscopy(DLTS) photoluminescence(PL) defects

Enhanced Precision Therapy of Multiple Myeloma Through Engineered Biomimetic Nanoparticles with dual Targeting

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Engineering 2024年第5期36卷 178-192页

作者： Ruogu Qi Shanshan Wang Jiayi Yu Tianming Lu Zhiqiang Bi Weibo Liu Yuanyuan Guo Yong Bian Jianliang Shen xuesong Zhang Wenhao Hu School of Medicine Nanjing University of Chinese MedicineNanjing 210023China Laboratory Animal Center Nanjing University of Chinese MedicineNanjing 210023China Key Laboratory of Carcinogenesis and Translational Research Ministry of Education/BeijingDepartment of Radiation OncologyBeijing Cancer HospitalBeijing 100142China Department of Orthopedics The Fourth Medical CenterThe Chinese People’s Liberation Army General HospitalBeijing 100853China State Key Laboratory of Ophthalmology Optometry and Vision ScienceSchool of Biomedical EngineeringWenzhou Medical UniversityWenzhou 325027China

Multiple myeloma(MM)is the second most prevalent hematological *** MM treatment strategies are hampered by systemic toxicity and suboptimal therapeutic *** study addressed these limitations through the development of a potent MM-targeting chemotherapy strategy,which capitalized on the high binding affinity of alendronate for hydroxyapatite in the bone matrix and the homologous targeting of myeloma cell membranes,termed T-PB@*** results from our investigations highlight the considerable bone affinity of T-PB@M,both in vitro and in ***,this material demonstrated a capability for drug release triggered by low pH ***,T-PB@M induced the generation of reactive oxygen species and triggered cell apoptosis through the poly(ADP-ribose)polymerase 1(PARP1)-Caspase-3-B-cell lymphoma-2(Bcl-2)pathway in MM ***,T-PB@M preferentially targeted bone-involved sites,thereby circumventing systemic toxic side effects and leading to prolonged survival of MM orthotopic ***,this designed target-MM nanocarrier presents a promising and potentially effective platform for the precise treatment of MM.

关键词： Multiple myeloma Bortezomib Drug delivery dual targeting Controlled release

Breeding exceptionally fragrant soybeans for soy milk with strong aroma

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Journal of Integrative Plant Biology 2024年第4期66卷 642-644页

作者： Hongtao Xie Minglei Song xuesong Cao Qingfeng Niu Jianhua Zhu Shasha Li Xin Wang Xiaomu Niu Jian-Kang Zhu Bellagen Biotechnology Co.Ltd. Jinan 250000China Institute of Advanced Biotechnology and School of Life Sciences Southern University of Science and TechnologyShenzhen 518055China School of Life Sciences Anhui Agricultural UniversityHefei 230036China Shandong Normal University Jinan 250000China

Soybean(Glycine max(L.)Merr.)is a major source of vegetable protein and oil in human diet and animal *** seeds have been extensively used in various food products and *** quality,particularly the aroma,affects cooking and eating,and ultimately influences consumer *** milk is particularly popular in China and has been gaining popularity in many other countries in the world.

关键词： exceptional soybean cooking

齿根裂纹对风电齿轮箱高速级动态特性影响分析及其故障模式识别

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太阳能学报 2022年第7期43卷 284-292页

作者：毕玉朱才朝谭建军宋海蓝杜雪松重庆大学机械传动国家重点实验室重庆400044

针对风电齿轮箱高速级齿轮传动系统齿根裂纹扩展程度识别难题,该文提出基于广义BP神经网络(GBPNN)的齿轮传动系统齿根裂纹故障模式识别方法。构建计及齿根裂纹扩展方向与路径的齿轮副时变啮合刚度解析模型及风电齿轮箱高速级齿轮-轴-轴... 详细信息

针对风电齿轮箱高速级齿轮传动系统齿根裂纹扩展程度识别难题,该文提出基于广义BP神经网络(GBPNN)的齿轮传动系统齿根裂纹故障模式识别方法。构建计及齿根裂纹扩展方向与路径的齿轮副时变啮合刚度解析模型及风电齿轮箱高速级齿轮-轴-轴承耦合的多自由度动力学模型,分析不同齿根裂纹扩展程度对系统振动特征的影响规律,并利用GBPNN对齿根裂纹故障模式进行识别。研究结果表明:齿轮故障振动周期冲击信号将沿着传动轴进行传递,但传动轴柔性会使其幅值产生明显的衰减;利用GBPNN并结合各轴段节点处振动加速度的峰值、峭度、统计矩阵参数以及方差,可有效实现对齿轮齿根裂纹故障模式的识别。

关键词：风电机组齿轮箱动力学模型故障识别时变啮合刚度齿根裂纹广义BP神经网络

Minimizing interfacial energy losses in inverted perovskite solar cells by a dipolar stereochemical 2D perovskite interface

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Journal of Energy Chemistry 2024年第3期90卷 496-503,I0011页

作者： Junjie Qian Jingjing He Qihang Zhang Chenyue Zhu Shilin Chen Zhanpeng Wei xuesong Leng Ziren Zhou Benben Shen Yu Peng Qiang Niu Shuang Yang Yu Hou Key Laboratory for Ultrafine Materials of Ministry of Education Shanghai Engineering Research Center of Hierarchical NanomaterialsSchool of Materials Science and EngineeringEast China University of Science and TechnologyShanghai 200237China National Enterprise Technology Center Inner Mongolia Erdos Electric Power and Metallurgy Group Company LimitedOrdos 016064Inner MongoliaChina

Inverted perovskite solar cells(PSCs) have attracted broad research and industrial interest owing to their suppressed hysteresis,cost-effectiveness,and ***,the issue of non-radiative recombination losses at the n-type interface between the perovskite and fullerene has impeded further improvement of photovoltaic ***,we modify the n-type interface of FAPbI_(3) perovskite films by constructing a stereochemical two-dimensional(2D) perovskite interlayer,in which the organic cations comprise both pyridine and ammonium *** pyridine N donor can create stable bonding with the surface-uncoordinated Pb on the perovskite,thereby passivating the shallow-level defects and enhancing the air stability of the ***,the pyridine N donor also offers a positive polar interface to decrease the surface work function of the perovskite film,enabling n-type ***,we employ a p-i-n photovoltaic(PV) device with the positive dipole interlayer at perovskite/fullerene contact and achieve remarkable photoelectric conversion efficiency(PCE) of 22.0%.

关键词： Perovskite solar cells Dipole interlayer Stereochemistry Non-radiative recombination