检索结果-南通市图书馆

Correlation analysis between lung ultrasound scores and pulmonary arterial systolic pressure in patients with acute heart failure admitted to the emergency intensive care unit

引用

Journal of Intensive Medicine 2024年第1期4卷 125-132页

作者： Ping Xu Basma Nasr Liang Li Wenbin Huang Wei liu xuelian Wang Emergency Department Zigong Fourth People’s HospitalZigongChina Institute of Medical Big Data Zigong Academy of Artificial Intelligence and Big Data for Medical ScienceZigongChina Artificial Intelligence Key Laboratory of Sichuan Province ZigongChina Department of Cardiology First Affiliated Hospital of Dalian Medical UniversityDalianChina

Background:No convenient,inexpensive,and non-invasive screening tools exist to identify pulmonary hypertension(PH)-left heart disease(LHD)patients during the early stages of the disease course.This study investigated whether different methods of lung ultrasound(LUS)could be used for the initial investigation of PH-LHD.Methods:This was a single-center prospective observational study which was performed in the Zigong Fourth People’s Hospital.We consecutively enrolled patients with heart failure(HF)admitted to the emergency intensive care unit from January 2018 to May 2020.Transthoracic echocardiography and LUS were performed within 24 h before discharge.We used the Spearman coefficient for correlation analysis between ultrasound scores and pulmonary arterial systolic pressure(PASP).Bland-Altman plots were generated to inspect possible bias,and receiver operating characteristic(ROC)curves were calculated to assess the relationship between ultrasound scores and an intermediate and high echocardiographic probability of PH-LHD.Results:Seventy-one patients were enrolled in this study,with an overall median age of 79(interquartile range:71.5–84.0)years.Among the 71 patients,36(50.7%)cases were male,and 26(36.6%)had an intermediate and high echocardiographic probability of PH.All four LUS scores in patients with an intermediate and high probability of PH were significantly higher than in patients with a low probability of PH(P<0.05).The correlation coefficient(r)between different LUS scoring methods and PASP was moderate for the 6-zone(r=0.455,P<0.001),8-zone(r=0.385,P=0.001),12-zone(r=0.587,P<0.001),and 28-zone(r=0.535,P<0.001)methods.In Bland-Altman plots,each of the four LUS scoring methods had a good agreement with PASP(P<0.001).The 8-zone and 12-zone methods showed moderately accurate discriminative values in differentiating patients with an intermediate and high echocardiographic probability of PH(P<0.05).

关键词： Acute heart failure Pulmonary arterial systolic pressure Pulmonary hypertension Left heart disease Lung ultrasound

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Phosphatidic acid-enabled MKL1 contributes to liver regeneration:Translational implication in liver failure

引用

Acta Pharmaceutica Sinica B 2024年第1期14卷 256-272页

作者： Jiawen Zhou Xinyue Sun xuelian Chen Huimin liu Xiulian Miao Yan Guo Zhiwen Fan Jie Li Yong Xu Zilong Li State Key Laboratory of Natural Medicines Department of PharmacologyChina Pharmaceutical UniversityNanjing 211198China Institute of Biomedical Research Liaocheng UniversityLiaocheng 252200China Department of Pathology Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical SchoolNanjing 210008China Department of Infectious Diseases Nanjing Drum Tower Hospital Affiliated with Nanjing University Medical SchoolNanjing 210008China Institute of Viruses and Infectious Diseases Nanjing UniversityNanjing 210008China

Liver regeneration following injury aids the restoration of liver mass and the recovery of liver function.In the present study we investigated the contribution of megakaryocytic leukemia 1(MKL1),a transcriptional modulator,to liver regeneration.We report that both MKL1 expression and its nuclear translocation correlated with hepatocyte proliferation in cell and animal models of liver regeneration and in liver failure patients.Mice with MKL1 deletion exhibited defective regenerative response in the liver.Transcriptomic analysis revealed that MKL1 interacted with E2F1 to program pro-regenerative transcription.MAPKAPK2 mediated phosphorylation primed MKL1 for its interaction with E2F1.Of interest,phospholipase d2 promoted MKL1 nuclear accumulation and liver regeneration by catalyzing production of phosphatidic acid(PA).PA administration stimulated hepatocyte proliferation and enhanced survival in a MKL1-dependent manner in a pre-clinical model of liver failure.Finally,PA levels was detected to be positively correlated with expression of pro-regenerative genes and inversely correlated with liver injury in liver failure patients.In conclusion,our data reveal a novel mechanism whereby MKL1 contributes to liver regeneration.Screening for small-molecule compounds boosting MKL1 activity may be considered as a reasonable approach to treat acute liver failure.

关键词： Liver failure Liver regeneration Transcription regulation Transcription factor Hepatocytes Phosphatidic acid Phospholipase d2 Translational medicine

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Earthworm regulation of nitrogen pools and dynamics and marker genes of nitrogen cycling: A meta-analysis

引用

Pedosphere 2022年第1期32卷 131-139页

作者： Rui XUE Chong WANG xuelian liu Mengli liu College of Resources Environmental SciencesChina Agricultural UniversityBeijing 100193China Beijing Key Laboratory of Biodiversity and Organic Farming Beijing 100193China State Key Laboratory of Direct-Fed Microbial Engineering Beijing Dabeinong Science and Technology Group Co.Ltd.(DBN)Beijing 100192China

Earthworms, as the ecosystem engineers, both directly and indirectly affect the nitrogen(N) cycle. We aimed to provide a quantitative assessment of the contribution of earthworms to the terrestrial ecosystem N cycle using meta-analysis of 130 publications selected. The natural logarithm of the response ratio(lnRR) was used to indicate the effect size of earthworms on N dynamic variables. The results showed that earthworms significantly affected soil N-cycling microorganisms, including the amoA gene abundance of soil ammonia-oxidizing bacteria(AOB), and significantly promoted soil N cycle processes,including denitrification, mineralization, and plant assimilation. The effects of earthworms on the N cycle were experimental design dependent and affected by factors such as the functional group of earthworm and residue input. The presence of the anecic earthworms decreased the rates of mineralization and nitrification, and increased nitrification and denitrification responses were more pronounced in the presence of the endogeic earthworms than that of the other two functional groups of earthworms. In addition, residue input enhanced the effects of earthworms on the N cycle. The effects of earthworms on nitrous oxide(N_(2) O) emission increased when residues were added. These findings indicate that residue input and introducing suitable functional groups of earthworms into the field can lead to N sustainability without increasing N2 O emission. This meta-analysis also provides systematic evidence for the positive effects of earthworms on the plant N pool, N availability(soil ammonium(NH_(4)^(+)) content), and soil microbial biomass N content, showing the potential to alter ecosystem functions and services in relation to N cycling.

关键词： ammonia-oxidizing bacteria denitrification earthworm functional group mineralization nitrification residue input

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

考虑供应商竞争的电子商务供应链物流服务模式优化研究

引用

中国管理科学 2024年第1期32卷 125-136页

作者：覃雪莲刘志学华中科技大学管理学院湖北武汉430074

本文在电子商务供应链物流服务模式决策过程中引入供应商竞争,通过构建由两个产品供应商、一个电子商务平台和众多消费者组成的电子商务供应链,研究提出了供应商竞争场景下的最优物流服务模式选择策略,进而分析了电子商务平台销售模式... 详细信息

本文在电子商务供应链物流服务模式决策过程中引入供应商竞争,通过构建由两个产品供应商、一个电子商务平台和众多消费者组成的电子商务供应链,研究提出了供应商竞争场景下的最优物流服务模式选择策略,进而分析了电子商务平台销售模式对最优策略的影响。研究结果表明:假若电子商务平台采用转售模式或平台模式,当市场竞争强度和物流服务成本绩效都很高时,供应商和电子商务平台都偏好采用差异化的物流服务运营策略;如果电子商务平台采用混合模式,两个供应商的物流服务模式偏好存在较大差异,但电子商务平台始终偏好同时为两个供应商的产品提供物流服务。

关键词：物流服务模式电子商务供应链电子商务平台供应商竞争销售模式

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

SiO_2@C hollow sphere anodes for lithium-ion batteries

引用

Journal of Materials Science & Technology 2017年第3期33卷 239-245页

作者： xuelian liu Yuxi Chen Hongbo liu Zhi-Quan liu College of Materials Science and Engineering/Hunan Province Key Laboratory for Spray Deposition Technology and Application Hunan University Shenyang National Laboratory for Materials Science Institute of Metal Research Chinese Academy of Sciences

As anode materials for lithium-ion batteries, SiO2 is of great interest because of its high capacity, low cost and environmental affinity. A facile approach has been developed to fabricate SiO2@C hollow spheres by hydrolysis of tetraethyl orthosilicate（TEOS） to form SiO2 shells on organic sphere templates followed by calcinations in air to remove the templates, and then the SiO2 shells are covered by carbon layers.Electron microscopy investigations confirm hollow structure of the SiO2@C. The SiO2@C hollow spheres with different SiO2 contents display gradual increase in specific capacity with discharge/charge cycling,among which the SiO2@C with SiO2 content of 67 wt% exhibits discharge/charge capacities of 653.4/649.6 mAh g^（-1） over 160 cycles at current density of 0.11 mA cm^（-2）. The impedance fitting of the electrochemical impedance spectroscopy shows that the SiO2@C with SiO2 content of 67 wt% has the lowest charge transfer resistance, which indicates that the SiO2@C hollow spheres is promising anode candidate for lithium-ion batteries.

关键词： Silica Hollow spheres Carbon coating Anode Lithium-ion batteries

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

全球治理的“内卷式”困境与中国的作为

引用

国际展望 2024年第3期16卷 74-92,156页

作者：刘雪莲卓晔吉林大学行政学院长春130012 云南大学国际关系学院昆明200020

2008年国际金融危机后,全球治理逐渐陷入困境,但与此同时全球治理中各类制度、规则广泛建立。现有研究解释不了全球治理失效但各类制度、规则又不断建立的现象。通过引入“内卷”概念,并分析全球治理“量的增长”与“质的停滞”的情形,... 详细信息

2008年国际金融危机后,全球治理逐渐陷入困境,但与此同时全球治理中各类制度、规则广泛建立。现有研究解释不了全球治理失效但各类制度、规则又不断建立的现象。通过引入“内卷”概念,并分析全球治理“量的增长”与“质的停滞”的情形,可以将全球治理所面临的问题称为“内卷式”困境,即全球治理中制度、规则数量的增长并未带来全球治理质的提升。究其原因,全球化进程中的矛盾性在全球治理层面的反映可以解释这种“内卷式”困境,包括国家内部的矛盾性引发对全球治理的质疑、国家主义阻碍了全球治理向全球主义的升级、大国竞争削弱了多元主体的协同性等。面对全球治理的“内卷式”困境,中国提出人类命运共同体理念,以“一带一路”建设推进区域治理发展,减少因大国竞争造成制度、规则间的不一致,为推动全球治理质的提升而贡献力量。

关键词：全球治理内卷国际制度复杂性中国外交

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Correction to:Nuclear m6A reader YTHDC1 regulates the scaffold function of LINE1 RNA in mouse ESCs and early embryos

引用

Protein & Cell 2022年第6期13卷 470-471页

作者： Chuan Chen Wenqiang liu Jiayin Guo Yuanyuan liu xuelian liu Jun liu Xiaoyang Dou Rongrong Le Yixin Huang Chong Li Lingyue Yang Xiaochen Kou Yanhong Zhao You Wu Jiayu Chen Hong Wang Bin Shen Yawei Gao Shaorong Gao Institute for Regenerative Medicine Shanghai East HospitalShanghai Key Laboratory of Signaling and Disease ResearchFrontier Science Center for Stem Cell ResearchSchool of Life Sciences and TechnologyTongji UniversityShanghai 200120China Clinical and Translation Research Center of Shanghai First Maternity&Infant Hospital Shanghai Key Laboratory of Signaling and Disease ResearchFrontier Science Center for Stem Cell ResearchSchool of Life Sciences and TechnologyTongji UniversityShanghai 200092China State Key Laboratory of Reproductive Medicine Department of Prenatal DiagnosisWomen’s Hospital of Nanjing Medical UniversityNanjing Maternity and Child Health Care HospitalNanjing Medical UniversityNanjing 211166China School of Life Sciences Peking UniversityBeijing 100871China Peking-Tsinghua Center for Life Sciences Peking UniversityBeijing 100871China Department of Chemistry and Institute for Biophysical Dynamics The University of ChicagoChicagoIL 60637USA Howard Hughes Medical Institute ChicagoIL 60637USA

CORRECTION TO:PROTEIN CELL(2021)HTTPS://***/10.1007/S13238-021-00837-8 In the original publication of the article figure 1 is incorrectly published.The correct Figure 1 is provided in this correction.OPEN ACCESS This article is licensed under a Creative Commons Attribution 4.0 International License,which permits use,sharing,adaptation,distribution and reproduction in any medium or format,as long as you give appropriate credit to the original author(s)and the source,provide a link to the Creative Commons licence,and indicate if changes were made.The images or other third party material in this article are included in the article's Creative Commons licence,unless indicated otherwise in a credit line to the material.If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use,you will need to obtain permission directly from the copyright holder.To view a copy of this licence,visit https://***/licenses/by/4.0/.

关键词： ACCESS HTTPS Figure

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hole-Doped Nonvolatile and Electrically Controllable Magnetism in van der Waals Ferroelectric Heterostructures

引用

Chinese Physics Letters 2024年第5期41卷 107-119页

作者：姜新新王智宽李冲孙雪莲杨磊李冬梅崔彬刘德胜 School of Physics National Demonstration Center for Experimental Physics EducationShandong UniversityJinan 250100China School of Physics and Microelectronics Zhengzhou UniversityZhengzhou 450001China

Electrical control of magnetism in van der Waals semiconductors is a promising step towards development of two-dimensional spintronic devices with ultralow power consumption for processing and storing information.Here, we propose a design for two-dimensional van der Waals heterostructures(vdWHs) that can host ferroelectricity and ferromagnetism simultaneously under hole doping. By contacting an In Se monolayer and forming an InSe/In_(2)Se_(3) vd WH, the switchable built-in electric field from the reversible out-of-plane polarization enables robust control of the band alignment. Furthermore, switching between the two ferroelectric states(P_↑ and P_↓)of hole-doped In_(2)Se_(3) with an external electric field can interchange the ON and OFF states of the nonvolatile magnetism. More interestingly, doping concentration and strain can effectively tune the magnetic moment and polarization energy. Therefore, this provides a platform for realizing multiferroics in ferroelectric heterostructures,showing great potential for use in nonvolatile memories and ferroelectric field-effect transistors.

关键词： polarization ferroelectric doping

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

基于大数据融合的应急物资可追溯信息挖掘模型构建

引用

计算机应用与软件 2024年第4期41卷 344-349页

作者：刘佳陈雪莲连鸿波国网江西省电力物资有限公司江西南昌330000 国网江西省电力有限公司信息通信分公司江西南昌330000 国网上海松江供电公司上海200000

传统的应急物资信息方法受到应急物资信息类型以及来源的影响,导致追溯效果不佳。为此,构建基于大数据融合的应急物资可追溯信息挖掘模型。选取巴科斯-诺尔范式规范化描述对应急物资可追溯信息,采用大数据融合匹配应急物资信息追溯结果... 详细信息

传统的应急物资信息方法受到应急物资信息类型以及来源的影响,导致追溯效果不佳。为此,构建基于大数据融合的应急物资可追溯信息挖掘模型。选取巴科斯-诺尔范式规范化描述对应急物资可追溯信息,采用大数据融合匹配应急物资信息追溯结果。通过Dasarathy信息融合模型设计三层递进模式,利用EM算法建立挖掘模型,实现对应急物资可追溯信息的有效挖掘。实验结果表明,采用该模型可有效挖掘应急物资可追溯信息,不同情况下挖掘精度均高于99%,并具有较高的实时性。

关键词：大数据融合应急物资可追溯信息挖掘模型

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Dendritic BiVO4 decorated with MnOx co-catalyst as an efficient hierarchical catalyst for photocatalytic ozonation

引用

Frontiers of Chemical Science and Engineering 2019年第1期13卷 185-191页

作者： Jin Yang xuelian liu Hongbin Cao Yanchun Shi Yongbing Xie Jiadong Xiao School of Chemical Engineering and Technology Tianjin University Tianjin 300072 China Beijing Engineering Research Center of Process Pollution Control CAS Key Laboratory of Green Process and Engineering Institute of Process Engineering Chinese Academy of Sciences Beijing 100190 China University of Chinese Academy of Sciences Beijing 100049 China

An appropriate co-catalyst can significantly promote the photocatalytic efficacy, but this has been seldom studied in the visible-light photocatalysis combined with ozone, namely photocatalytic ozonation. In this work, a dendritic bismuth vanadium tetraoxide (BiVO4) material composited with highly dispersed MnOv nanoparticles was synthesized, and its catalytic activity is 86.6% higher than bare BiVO4 in a visible light and ozone combined process. Catalytic ozonation experiments, ultraviolet- visible (UV-Vis) diffuse reflectance spectra and photoluminescence spectra jointly indicate that MnOA plays a triple role in this process. MnOv strengthens the light adsorption and promotes the charge separation on the composite material, and it also shows good activity in catalytic ozonation. The key reactive species in this process is OH, and various pathways for its generation in this process is proposed. This work provides a new direction of catalyst preparation and pushes forward the application of photocatalytic ozonation in water treatment.

关键词： manganese oxide bismuth vanadium tetraoxide photocatalytic ozonation hydroxyl radical cocatalyst

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：