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第三方合作存款与商业银行风险承担

金融研究 2022年第9期 39-56页

作者：吕之安郭雪寒刘冲刘莉亚上海国际金融与经济研究院上海200433 上海财经大学金融学院上海200433

近年来与第三方互联网平台合作推出存款产品一度成为部分中小银行吸收存款的重要手段,监管部门对此高度关注并出台监管措施,但相关的学术研究较为匮乏。本文基于国内上市银行2012—2020年的面板数据,实证分析开展第三方合作存款业务对... 详细信息

近年来与第三方互联网平台合作推出存款产品一度成为部分中小银行吸收存款的重要手段,监管部门对此高度关注并出台监管措施,但相关的学术研究较为匮乏。本文基于国内上市银行2012—2020年的面板数据,实证分析开展第三方合作存款业务对银行风险承担的影响并考察内在机理。研究发现,开展该业务显著提高了银行风险承担水平,表现为加权风险资产的扩张及高风险行业信贷资产配置的提升。机制研究表明,合作银行的储蓄存款规模显著扩张,流动性资金的过快增长刺激银行信贷向高利率贷款、高风险行业倾斜。本文研究对完善互联网存款监管,防控商业银行风险具有一定的启示意义。

关键词：第三方合作存款风险承担金融创新金融监管

扶贫的企业力量——来自中国上市公司扶贫效果的证据

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财贸经济 2022年第1期43卷 138-152页

作者：刘莉亚周舒鹏庞元晨郭雪寒上海财经大学金融学院党委 200433 上海财经大学金融学院 200433

随着扶贫攻坚进入新时期,以政府为主导的扶贫攻坚面临诸多约束与局限,亟须广泛动员社会力量,尤其是企业力量共同参与。为回答企业的扶贫参与是否有效,以及地区差异对其是否有影响,本文利用2010—2017年A股上市公司所发布的企业社会责任... 详细信息

随着扶贫攻坚进入新时期,以政府为主导的扶贫攻坚面临诸多约束与局限,亟须广泛动员社会力量,尤其是企业力量共同参与。为回答企业的扶贫参与是否有效,以及地区差异对其是否有影响,本文利用2010—2017年A股上市公司所发布的企业社会责任报告信息,对企业扶贫参与的效果进行了研究。研究发现:(1)西部地区的企业、与消费者直接接触的企业以及规模大、经营业绩好的企业更倾向于参与扶贫攻坚;(2)企业的扶贫参与有助于提高农村居民人均收入,且在欠发达地区,企业参与扶贫的效果更好。这表明以企业为代表的社会力量响应了国家精准扶贫的号召,履行了企业社会责任,确实有助于巩固脱贫成果,实现欠发达地区的脱贫。本文基于企业参与扶贫的视角,拓展了扶贫攻坚另一参与主体——社会力量的相关研究,同时也丰富了企业履行社会责任所带来的社会效益的相关文献。

关键词：企业社会责任反贫困企业扶贫参与

食管癌根治性放化疗后局部区域复发再程治疗的全因性评估和预后分析

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中华放射医学与防护杂志 2024年第11期44卷 936-943页

作者：李曙光吴迪王晓斌郭雪涵沈文斌祝淑钗河北医科大学第四医院放疗科石家庄050011 承德医学院附属医院肿瘤科承德067020

目的系统性评估食管癌根治性放化疗后局部区域复发患者再程治疗后相关的全因性预后因素,为食管癌复发患者精准个体化治疗方案的选择和改善预后生存提供临床参考依据。方法回顾性分析2008年1月至2017年12月在河北医科大学第四医院放疗科... 详细信息

目的系统性评估食管癌根治性放化疗后局部区域复发患者再程治疗后相关的全因性预后因素,为食管癌复发患者精准个体化治疗方案的选择和改善预后生存提供临床参考依据。方法回顾性分析2008年1月至2017年12月在河北医科大学第四医院放疗科接受根治性放化疗后出现局部区域复发且间隔1年以上的85例食管癌患者的临床资料,比较不同的营养免疫状态和再程治疗模式对预后生存的影响,并对影响再程治疗的预后因素进行亚组综合分析。结果截至2021年12月,全组随访率为93%。全组患者再程治疗后1、2、3、5年总生存率分别为31.5%、18.6%、10.6%、6.6%。其中,接受放疗或放化疗者1、2、3、5年生存率分别为36.8%、22.3%、13.0%、9.3%。多因素分析显示,患者首次治疗至复发间隔时间、复发后再治疗模式、再治疗前白蛋白水平和再治疗前预后营养指数(PNI)是影响再治疗后生存的独立性因素(P<0.05)。进一步将再程治疗前外周血血红蛋白水平、白蛋白水平、PNI、疗后系统免疫炎症指数(SII)、近期疗效等组合后分组分析,结果显示将血常规和血清白蛋白指标综合分析,可准确预测再程治疗后的生存。结论食管癌放化疗后局部区域复发再治疗时,患者的营养免疫状态对预后有预测作用,复发间隔时间和再治疗模式显著影响再治疗后生存,疗前应严格评估并精准选择治疗方案,提高获益比。

关键词：食管肿瘤复发再程治疗预后放疗

Complete nucleotide sequence of a novel porcine circovirus-like agent and its infectivity in vitro

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Science China(Life Sciences) 2008年第5期51卷 453-458页

作者： WEN LiBin1, HE KongWang1, YANG HanChun2, NI YanXiu1, ZHANG xuehan1, guo RongLi1 & PAN QunXin1 1 Key Laboratory of Animal and Poultry Diseases Diagnostic of the Ministry of Agriculture, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China 2 Key Laboratory of Preventive Veterinary Medicine of Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing 100094, China Key Laboratory of Animal and Poultry Diseases Diagnostic of the Ministry of Agriculture Jiangsu Academy of Agricultural Sciences Nanjing China Key Laboratory of Preventive Veterinary Medicine of Ministry of Agriculture College of Veterinary Medicine China Agricultural University Beijing China

A novel agent (hence termed as P2) was isolated from pig sera in China, which contained covalently bound circular genomic DNAs of 993 nucleotides. Sequence analyses indicated that the agent was closely related to the porcine circovirus (PCV). The molecular clone of P2 was constructed subsequently and used for the following studies. Intracytoplasmic inclusions and intranuclear inclusions were only found in PK-15 cells transfected with the tandem dimer of P2 molecular DNA clone. Intracytoplasmic inclusions were round or irregular in shape and 0.1-0.4 μm in diameter, and intranuclear inclusions were electronically denser than intracytoplasmic inclusions and had two general shapes: round/small (0.1 μm in diameter) and hexagonal/large (0.5―1.4 μm in diameter). The inclusions were not membranously bound. The cells transfected with the tandem dimer of P2 molecular DNA clone were tested positive for P2 DNA at passages 5. The P2 antigen could be detected in both transfected and passaged PK-15 cells. This is the first report regarding the complete nucleotide sequence of a small DNA genome in a circovirus-like infectious agent in vitro.

关键词： P2 porcine circovirus molecular clone PK-15 cells

Simple synthesis of BiOI/ZnO/rGO for efficient photocatalytic degradation of antibiotic chloramphenicol under visible light

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Journal of Environmental Sciences 2023年第12期134卷 65-76页

作者： Zihan Zhu Feng guo Anming Li Weichao Xu xuehan Zhang School of Ocean Science and Technology Dalian University of TechnologyPanjin 124221China

BiOI/ZnO/rGO(reduced graphene oxide) composite photocatalyst was fabricated using a simple one-step hydrothermal process and applied to the degradation of antibiotic chloramphenicol(CAP). By tuning the Bi/Zn ratios, the structure and photoelectric properties of the catalyst were investigated and characterized in terms of their morphological, structural, optical and photoelectrochemical properties. The as-synthesized composite photocatalysts are well-crystalline, uniform dispersion and exhibit good photocatalytic *** photocatalytic degradation rate of CAP by BiOI/ZnO/rGO composite is 8.1 times and 1.8times that of BiOI and ZnO, respectively. The photocatalytic mechanism studies revealed that the synergistic effect between rGO and BiOI/ZnO can effectively separate photogenerated electron–hole, enhance photocurrents and conductivity, and improve charge carrier densities. Moreover, BiOI/ZnO/rGO possesses good stability and reusability that the degradation efficiency remained above 80% even after 5 recycling. This study reveals that both the introduction of rGO and heterostructure construction between BiOI and ZnO play a crucial role in their photoelectrochemical and photocatalytic properties.

关键词： BiOI/ZnO/rGO(reduced graphene oxide) Photodegradation Chloramphenicol Visible light

PNI对颈胸上段食管鳞癌患者预后及放射性食管炎预测价值

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中华放射肿瘤学杂志 2023年第8期32卷 689-696页

作者：李曙光陈俊强李幼梅郭雪涵邓文钊王晓斌祝淑钗沈文斌河北医科大学第四医院放疗科石家庄050011 福建省肿瘤医院放疗科福州350014

目的探讨治疗前小野寺预后营养指数(PNI)对接受根治性放化疗颈胸上段食管鳞癌(CUTESCC)患者预后的影响和对≥2级放射性食管炎发生的预测价值。方法回顾性分析河北医科大学第四医院2012年1月至2017年12月符合入组条件的163例CUTESCC患者... 详细信息

目的探讨治疗前小野寺预后营养指数(PNI)对接受根治性放化疗颈胸上段食管鳞癌(CUTESCC)患者预后的影响和对≥2级放射性食管炎发生的预测价值。方法回顾性分析河北医科大学第四医院2012年1月至2017年12月符合入组条件的163例CUTESCC患者的资料。应用受试者操作特征(ROC)曲线计算PNI预测患者预后的最佳截止值, 对患者的预后进行单因素和Cox多因素分析。logistic二元回归模型用于单因素和多因素分析≥2级放射性食管炎(RE)的危险因素, 将logistic多因素分析中具有统计学意义的因素用来构建预测≥2级RE的列线图。结果 PNI的最佳截止值为48.57[曲线下面积(AUC)=0.653, P<0.001]。全组患者中位总生存(OS)和无进展生存(PFS)期分别为26.1、19.4个月。PNI≥48.57组(47例)患者的OS(χ2=6.900, P=0.009)和PFS(χ2=9.902, P=0.003)均显著优于PNI<48.57组(116例)。Cox多因素分析显示, 患者cTNM分期和PNI为影响患者OS(HR=1.513, 95%CI为1.193~1.920, P=0.001;HR=1.807, 95%CI为1.164~2.807, P=0.008)和PFS(HR=1.595, 95%CI为1.247~2.039, P<0.001;HR=2.260, 95%CI为1.439~3.550, P<0.001)的独立性预测指标, 近期疗效为影响患者PFS的另一独立性指标(HR=2.072, 95%CI为1.072~4.003, P=0.030)。logistic多因素分析显示, 病变最大横径(OR=3.026, 95%CI为1.266~7.229, P=0.013)、大体肿瘤体积(GTV)(OR=3.456, 95%CI为1.373~8.699, P=0.008)、处方剂量(OR=3.124, 95%CI为1.346~7.246, P=0.009)和PNI(OR=2.072, 95%CI为1.072~4.003, P=0.030)是影响患者出现≥2级RE的独立性因素。将这4项指标纳入列线图模型:ROC曲线分析显示, 该模型可以较好地预测患者≥2级RE的发生(AUC=0.686, 95%CI为0.585~0.787);校正曲线显示, 实际观测值与预测RE之间具有良好的一致性;决策曲线分析显示, 在大多数阈值概率中列线图正净收益令人满意。结论治疗前小野寺PNI为接受根治性放化疗颈胸上段食管鳞癌患者的独立性预后影响因素;病变最大横径、GTV、处方剂量和PNI这4项指标为本组患者出现≥2级放射性食管炎的危险因素, 建立包含这些因素的预测模型, 预测价值更大。

关键词：食管肿瘤,鳞状细胞放射性食管炎根治性放化疗列线图预后营养指数

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添加木醋液和生物炭对堆肥重金属钝化的影响

农业机械学报 2023年第S2期54卷 330-340页

作者：付雪寒郭潇君刘龙周岭塔里木大学机械电气化工程学院阿拉尔843300 新疆维吾尔自治区教育厅普通高校现代农业工程重点实验室阿拉尔843300

腐殖质(HS)是有机肥养分质量的重要指标。在堆肥过程中,生物炭和棉秆木醋液的添加会导致堆体内部环境发生变化,但HS的化学性质变化尚不明确。本研究利用火焰原子吸收仪检测了重金属(HMs)(例如Pb、Cr、Cd、Ni)的形态,运用傅里叶变换红外... 详细信息

腐殖质(HS)是有机肥养分质量的重要指标。在堆肥过程中,生物炭和棉秆木醋液的添加会导致堆体内部环境发生变化,但HS的化学性质变化尚不明确。本研究利用火焰原子吸收仪检测了重金属(HMs)(例如Pb、Cr、Cd、Ni)的形态,运用傅里叶变换红外光谱(FTIR)方法和三维激发发射矩阵荧光光谱(3D-EEM)方法以多个角度表征HS与HMs的络合物。同时,采用数理统计、相关性分析和冗余分析(Redundancy analyses,RDA)比较了试验组的腐熟指标(温度、pH值)、腐殖化能力(HS、富里酸(FA)、胡敏酸(HA)、胡敏酸与富里酸之比(H/F))、官能团等。研究结果显示,木醋液处理能使堆肥腐殖化程度相对较高,且位于波数876~835 cm^(-1)的峰值明显增强表明芳香结构在不断累积,H/F最终均达到2.3以上。T1处理组生物炭处理的HS含量位于T4和T3处理组之间,H/F最终达到3.67。T1处理组对Cr钝化过程,交换态最终钝化比例至2%。T4处理组在Pb钝化过程中,最终残渣态的比例高达68%。Cd受T4处理组影响较大,最终表现为氧化态分别向交换态、还原态、残渣态转移2%、10%和11%。然而,无论是添加生物炭还是木醋液,对Ni的钝化在堆制过程中均未显示出明显趋势,交换态、还原态、氧化态和残渣态比例分别稳定在1%~2%、5%~7%、26%~35%和56%~68%,说明本次试验HS对Ni的影响较小。FTIR进一步证实了HS作为富含芳香族和羧基的核心农艺功能物质的基本特性。在堆肥过程中,HS的芳香性逐渐增加,从而增强了与Pb、Cr、Cd离子的络合能力。此外,研究确定了质量分数1.75%的木醋液在猪粪基料堆制过程中整体表现较佳。综上所述,木醋液和生物炭存在以下吸附机制:木醋液的特殊功能基团与HMs离子发生络合作用;生物炭与HMs主要依赖吸附作用;Ni在堆肥中的作用机制可能更倾向于与硝酸根离子结合。

关键词：堆肥腐殖质重金属生物炭木醋液光谱

Glossy15 Plays an Important Role in the Divergence of the Vegetative Transition between Maize and Its Progenitor, Teosinte

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Molecular Plant 2017年第12期10卷 1579-1583页

作者： Dingyi Xu Xufeng Wang Cheng Huang Guanghui Xu Yameng Liang Qiuyue Chen Chenglong Wang Dan Li Jinge Tian Lishuan Wu Yaoyao Wu Li guo xuehan Wang Weihao Wu Weiqiang Zhang Xiaohong Yang Feng Tian National Maize Improvement Center of China Beijing Key Laboratory of Crop Genetic Improvement Laboratory of Crop Heterosis and Utilization China Agricultural University Beijing 100193 China Department of Crop Physiology and Cultivation China Agricultural University Beijing 100193 China

Dear Editor,The timing of developmental transitions is important for plant growth and environmental adaptation. All plants undergo a series of developmental transitions during their life cycles, and each of these phases is characterized by unique morphological and physiological attributes （Baurle and Dean, 2006）. In maize, the vegetative transition from juvenile-to-adult vegetative development occurs in a coordinated manner and is marked by the production of leaves that differ in a suite of morphological and physiological traits, many of which contribute to fitness and crop productivity （Moose and Sisco, 1994）. Significant advances have been made in understanding the molecular mechanisms regulating the juvenile-to-adult vegetative transition.

关键词：

SUMOylation-triggered ALIX activation modulates extracellular vesicles circTLCD4-RWDD3 to promote lymphatic metastasis of non-small cell lung cancer

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Signal Transduction and Targeted Therapy 2023年第12期8卷 5887-5903页

作者： Xiayao Diao Chao guo Hanhao Zheng Ke Zhao Yuming Luo Mingjie An Yan Lin Jiancheng Chen Yuanlong Li Yuting Li xuehan Gao Jiaqi Zhang Mengxin Zhou Wenliang Bai Lei Liu Guige Wang Lanjun Zhang Xiaotian He Rusi Zhang Zhihua Li Changhao Chen Shanqing Li Department of Thoracic Surgery Peking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingP.R.China Department of Urology Sun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhouGuangdongP.R.China Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation Sun Yat-sen Memorial HospitalState Key Laboratory of Oncology in South ChinaGuangzhouGuangdongP.R.China Department of General Surgery Guangdong Provincial People’s HospitalGuangdong Academy of Medical SciencesGuangzhouGuangdongP.R.China Cancer Center Renmin Hospital of Wuhan UniversityWuhanHubeiP.R.China Department of Thoracic Surgery Sun Yat-sen University Cancer CenterSun Yat-sen UniversityGuangzhouGuangdongP.R.China Department of Medical Oncology Sun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhouGuangdongP.R.China

Lymph node(LN)metastasis is one of the predominant metastatic routes of non-small cell lung cancer(NSCLC)and is considered as a leading cause for the unsatisfactory prognosis of *** lymphangiogenesis is well-recognized as a crucial process in mediating LN metastasis,the regulatory mechanism involving lymphangiogenesis and LN metastasis in NSCLC remains *** this study,we employed high-throughput sequencing to identify a novel circular RNA(circRNA),circTLCD4-RWDD3,which was significantly upregulated in extracellular vesicles(EVs)from LN metastatic NSCLC and was positively associated with deteriorated OS and DFS of patients with NSCLC from multicenter clinical *** the expression of EV-packaged circTLCD4-RWDD3 inhibited lymphangiogenesis and LN metastasis of NSCLC both in vitro and in ***,circTLCD4-RWDD3 physically interacted with hnRNPA2B1 and mediated the SUMO2 modification at K108 residue of hnRNPA2B1 by upregulating ***,circTLCD4-RWDD3-induced SUMOylated hnRNPA2B1 was recognized by the SUMO interaction motif(SIM)of ALIX and activated ALIX to recruit ESCRT-III,thereby facilitating the sorting of circTLCD4-RWDD3 into NSCLC cell-derived ***,EV-packaged circTLCD4-RWDD3 was internalized by lymphatic endothelial cells to activate the transcription of PROX1,resulting in the lymphangiogenesis and LN metastasis of ***,blocking EV-mediated transmission of circTLCD4-RWDD3 via mutating SIM in ALIX or K108 residue of hnRNPA2B1 inhibited the lymphangiogenesis and LN metastasis of NSCLC in *** findings reveal a precise mechanism underlying SUMOylated hnRNPA2B1-induced EV packaging of circTLCD4-RWDD3 in facilitating LN metastasis of NSCLC,suggesting that EV-packaged circTLCD4-RWDD3 could be a potential therapeutic target against LN metastatic NSCLC.

关键词： metastasis inhibited lymphatic