检索结果-南通市图书馆

Effect of dietary with Zhibai dihuang pills and gonadotropinreleasing-hormone-analogue on girls with precocious and rapidly progressive puberty

引用

World Journal of Clinical Cases 2024年第24期12卷 5534-5541页

作者： xue-mei wang Wei Li Liu-Qing Yang Rui Luo Chen-Chen Zhang Department of Pediatrics Ma’anshan Maternal and Child Health HospitalMa’anshan 243011Anhui ProvinceChina

BACKGROUND At present,the clinical mechanisms underlying precocious puberty remain unclear,making effective intervention for children experiencing this condition and rapidly progressive puberty *** To explore the effects of Zhibai dihuang pills and gonadotropin-releasing hormone analogue(GnRHa)on growth and ovarian function in girls with precocious *** The clinical data of 84 adolescent girls with precocious puberty and rapidly progressive puberty from February 2017 to August 2023 were retrospectively *** were divided into a control group and an observation group,with 42 cases in each *** control group received diet intervention combined with GnRHa treatment,while the observation group received diet intervention combined with Zhibai dihuang pills+GnRHa *** such as clinical efficacy,growth indicators,ovarian function,and adverse reactions were compared between the two *** The observation group showed superior clinical efficacy compared to the control group(P0.05).Post-intervention,the observation group exhibited significantly lower rates in growth,height,and bone age,along with reduced levels of progesterone,testosterone,estradiol,prolactin,luteinizing hormone,and follicle-stimulating hormone compared to the control group(P0.05).CONCLUSION Combining Zhibai dihuang pills with GnRHa and dietary intervention effectively improves growth,enhances ovarian function,and minimizes adverse reactions in adolescent girls with precocious and rapidly progressive puberty.

关键词： Zhibai dihuang pills Gonadotropin-releasing hormone analogue Dietary intervention Precocious puberty Rapidly progressive puberty Ovarian function

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Fast generation of W state via superadiabatic-based shortcut in circuit quantum electrodynamics

引用

Chinese Physics B 2021年第3期30卷 61-67页

作者： xue-mei wang An-Qi Zhang Peng Xu Sheng-mei Zhao Institute of Signal Processing and Transmission Nanjing University of Posts and TelecommunicationsNanjing 210003China

We propose a scheme to fast prepare the three-qubit W state via superadiabatic-based shortcuts in a circuit quantumelectrodynamics (circuit QED) system. We derive the effective Hamiltonian to suppress the unwanted transitions betweendifferent eigenstates by counterdiabatic driving, and obtain the W state with high-fidelity based on the superadiabaticpassage. The numerical simulation results demonstrate that the proposed scheme can accelerate the evolution, and is moreefficient than that with the adiabatic passage. In addition, the proposed scheme is robust to the decoherence caused by theresonator decay and qubit relaxation, and does not need additional parameters, which could be feasible in experiment.

关键词： W state superadiabatic-based shortcut circuit quantum electrodynamics

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Mediating the Migration of Mesenchymal Stem Cells by Dynamically Changing the Density of Cell-selective Peptides Immobilized on β-Cyclodextrin-modified Cell-resisting Polymer Brushes

引用

高分子科学：英文版 2020年第9期38卷 126-136,I0005页

作者： wang Du De-Teng Zhang xue-mei wang Tan-Chen Ren Chang-You Gao Ministry of Education Key Laboratory of Macromolecular Synthesis and Functionalization Department of Polymer Science and Engineering Zhejiang University

Dynamic control of mesenchymal stem cell(MSC)behaviors on biomaterial surface is critically involved in regulating the cell fate and tissue ***,a stimuli-responsive surface based on host-guest interaction with cell selectivity was developed to regulate migration of MSCs in situ by dynamic display of cell-specific ***-grafted MSC-affinitive peptides(EPLQLKM,Azo-E7)were grafted toβ-cyclodextran(β-CD)-modified poly(2-hydroxyethyl methacrylate)-b-poly(2-hydroxyethyl methacrylate-co-glycidyl methacrylate)(PHG)brushes,which were prepared by using surface-initiated atom transfer radical polymerization(SI-ATRP).X-ray photoelectron spectroscopy(XPS),quartz crystal microbalance(QCM),and water contact angle were used to characterize their structure and *** adhesion assay showed that the combination effect of resisting property of PHG and MSC-affinity of E7 could promote the selective adhesion of MSCs over other types of cells such as RAW264.7 macrophages and NIH3 T3 fibroblasts to some ***-Vis spectroscopy proved that the competing guest molecules,amantadine hydrochloride(Ama),could release Azo-E7 peptides from the CD surface to different extents,and the effect was enhanced when UV irradiation was employed *** a result,the decrease of cell adhesion density and migration rate could be achieved in *** cell density and migration rate could be reduced by over 40%by adding 20μmol/L Ama,suggesting that this type of surface is a new platform for dynamic regulation of stem cell behaviors in situ.

关键词： Host-guest interaction MSC-affinitive peptide Dynamic surface Cell adhesion Cell migration

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Impact of Multidisciplinary Collaborative Intervention on Isolation Implementation in Prevention and Control of Multi-drug Resistance Infection

引用

Current Medical Science 2023年第1期43卷 198-205页

作者： Ying wang Xin-ping ZHANG Xiao-quan LAI xue-mei wang Naning Drum Tower Hospital Affiated to Nanjing University Medical School Nanjing210008China School of Medicine and Health Management Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China Department of Nosocomial Infection Management Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China

Objective Contact precautions,especially the initiation of isolation,are important measures to prevent and control multidrug-resistant organisms(MDROs).However,the implementation in clinical practice remains *** study aimed to analyze the impact of multidisciplinary collaborative intervention on isolation implementation in multidrug-resistant infection,and determine the factors that affect the implementation of isolation *** A multidisciplinary collaborative intervention related to isolation was conducted at a teaching tertiary hospital in central China on November 1,*** information of 1338 patients with MDRO infection and colonization at 10 months before and after the intervention was ***,the issuance of isolation orders was retrospectively *** analysis and multivariate logistic regression analysis were performed to analyze the factors that affected the isolation *** The overall issuance rate of isolation orders was 61.21%,which increased from 33.12%to 75.88%(P<0.001)after the implementation of the multidisciplinary collaborative *** intervention(P<0.001,OR=0.166)was a promoting factor for the issuance of isolation orders,in addition to the length of stay(P=0.004,OR=0.991),department(P=0.004),and microorganism(P=0.038).Conclusion The isolation implementation remains far lower than policy *** collaborative interventions can effectively improve the compliance to isolation measures implemented by doctors,thereby promoting the standardized management of MDROs,and providing reference for further improving the quality of hospital infection management.

关键词： multidisciplinary collaborative intervention issuance of isolation orders multidrug-resistant organism infection and colonization isolation implementation rate

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Anemia status of infants and young children aged six to thirty-six months in Ma'anshan City:A retrospective study

引用

世界临床病例杂志 2023年第28期11卷 6744-6753页

作者： xue-mei wang Qiong-Yao wang Jie Huang Department of Pediatric Ma’anshan Maternal and Child Health CenterMa’anshan 243011Anhui ProvinceChina Department of Hematology and Oncology Children's Hospital of Nanjing Medical UniversityNanjing 210000Jiangsu ProvinceChina

BACKGROUND Anemia in infants and young children can have long-term effects on cognitive and physical *** Ma'anshan City,China,there has been growing concern about the prevalence of anemia among children aged 6 to 36 *** the factors influencing this condition is crucial for targeted interventions and improving overall child health in the *** To analyze the anemia status and influencing factors of infants and young children aged 6 to 36 mo in Ma'anshan City,*** scientific evidence for reducing the incidence of anemia and improving the health level of children in this age *** The study encompassed 37698 infants and young children,aged from 6 to 36 mo,who underwent health examinations at the Ma'anshan Maternal and Child Health Hospital from January 2018 to October 2022 were included in the *** information,physical examination,and hemoglobin detection data were *** analysis was used to analyze the prevalence of anemia in children in the region,and univariate analysis was used to analyze the influencing factors of *** The mean hemoglobin level of infants and young children aged 9 to 36 mo increased with age,and the anemia detection rate decreased with *** anemia detection rate in rural infants aged 6,9,and 12 mo was higher than that in urban *** the anemia detection rate was higher in 6-mo-old boys than girls,it was higher in 24-mo-old girls than *** were statistically significant differences in the anemia detection rates among 9-mo-old and 12-mo-old infants with different nutritional statuses(emaciation,overweight,obese,and normal).Moreover,there were no statistically significant differences in anemia detection rates among infants and young children with different nutritional statuses at other ***,the anemia detection rates in obese infants aged 9 and 12 mo were higher than those in normal and overweight infants,with statistically significant differe

关键词： Infants Children Anemia Hemoglobin Anemia detection rates

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Graphene-gold Nanoparticle Composite Film Modified Electrode for Determination of Trace Mercury in Environmental Water

引用

Chinese Journal of Chemical Physics 2013年第5期26卷 590-596,I0004页

作者： xue-mei wang Shou-guo Wu Hao Liu Lei Zhou Qi-ping Zhao Department of Chemistry University of Science and Technology of China Hefei 230025 China

The graphene-gold nanoparticles composite film modified glassy carbon electrode （EG- AuNPs/GCE） was prepared by one-step coelectrodeposition and employed for determination of trace mercury in environmental water with differential pulse stripping voltammetry. Such a nanostructured composite film combined with the advantages of gold nanoparticles and graphene, can greatly promote the electron-transfer process and increase accumulation abil-ity for Hg（Ⅱ）, leading to a remarkably improved sensitivity. The linear calibration curve ranged from 0.2 μg/L to 30 μg/L for Hg（Ⅱ） and the detection limit （S/N=3） was found to be 0.03 μg/L at a deposition time of 300 s. Moreover, the stablity of the as-prepared electrode and interferences from other substances were evaluated. The modified electrode was successfully applied to the direct detection of Hg（Ⅱ） in real water samples.

关键词： Graphene-gold nanoparticle composite membrane Chemically modified elec-trode Mercury Stripping voltammetry

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

1-Pyrenecarboxaldehyde thiosemicarbazone:A novel fluorescent molecular sensor towards mercury(Ⅱ) ion

引用

Chinese Chemical Letters 2010年第9期21卷 1124-1128页

作者： xue mei wang Hua Yan Xin Lu Feng Yong Chen Department of Chemistry and Material Engineering Logistic Engineering University Chongqing 401311 China Department of Applied Oil Engineering Logistic Engineering University Chongqing 401311 China Department of Barracks Management & Environmental Engineering Logistic Engineering University Chongqing 401311 China

A novel and simple fluorescent molecular sensor,1-pyrenecarboxaldehyde thiosemicarbazone（Hpytsc）,was *** higher sensitivity and selectivity to mercury（Ⅱ） ion were studied through absorption and emission *** UV-vis spectra show that the increasing mercury（Ⅱ） ion concentrations result in the decreasing absorption *** fluorescence monomer emission of Hpytsc is enhanced upon binding mercury（Ⅱ） ion,which should be due to the 1：1 complex formation between Hpytsc and metal ion.

关键词： Fluorescence sensor Mercury(Ⅱ) ion Pyrene derivatives Thiosemicarbazone

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A Study of the Probe Effect on the Apparent Image of Biological Atomic Force Microscopy

引用

Chinese Chemical Letters 2001年第12期12卷 1113-1114页

作者： xue mei wang Lei QIN Long BA Zu Hong LU The State Key Lab of Coordination Chemistry Nanjing UniversityNanjing 210093 National Lab of Molecular and Biomolecular Electronics Southeast UniversityNanjing 210096

The probe effect on the apparent image of biological atomic force microscopy was explored in this study, and the potential of AFM in conformational study of gene related biological processes was illustrated by the spe... 详细信息

关键词： atomic force microscopy (AFM) absorption DNA recognition

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Artifacts in two-dimensional shear wave elastography of liver

引用

World Journal of Gastroenterology 2023年第21期29卷 3318-3327页

作者： Hui-Peng wang Peng-Chao Zheng xue-mei wang Liang Sang Department of Ultrasound The First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina

BACKGROUND Artifacts are common when using two-dimensional shear wave elastography(2-D SWE)to measure liver stiffness(LS),but they are poorly *** To investigate the presence and influence of artifacts in 2-D SWE of *** We included 158 patients with chronic liver disease,who underwent 2-D SWE examination by a novice and an expert.A cross line at the center of the elastogram was drawn and was divided it into four locations:top-left,top-right,bottom-left,and *** occurrence frequency of artifacts in different locations was *** influence of artifacts on the LS measurements was evaluated by comparing the elastogram with the most artifacts(EMA)and the elastogram with the least artifacts(ELA).RESULTS The percentage of elastograms with artifacts in the novice(51.7%)was significantly higher than that of the expert(19.6%)(P<0.001).It was found that both operators had the highest frequency of artifacts at bottom-left,followed by top-left and bottom-right,and top-right had the lowest *** LS values(LSVs)and standard deviation values of EMAs were significantly higher than those of ELAs for both *** intraclass correlation coefficient value of 0.96 was found in the LSVs of EMAs of the two operators,and it increased to 0.98 when the LSVs of the ELAs were *** operators had lower stability index values for EMAs than ELAs,but the difference was only statistically significant for the *** Artifacts are common when using 2-D SWE to measure LS,especially for the *** may lead to the overestimation of LS and reduce the repeatability and reliability of LS measurements.

关键词： Ultrasound Elastography Artifact Liver

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Electrochemical study of the effect of functionalized nickel nanoparticles on cellular uptake of leukemia cancer cells in vitro

引用

Chinese Chemical Letters 2008年第5期19卷 577-580页

作者： Da Dong Guo Chun Hui Wu xue mei wang Bao An Chen State Key Lab of Bioelectronics （Chien-Shiung Wu Lab） Southeast University Nanjing 210096 China Zhongda Hospital School of Clinical Medical Southeast University Nanjing 210096 China

In this study, we have fabricated the functionalized nickel nanoparticles and investigated their effects on cellular uptake of quercetin in leukemia K562 cancer cells by using electrochemical assay. The results indicate that nickel nanoparticles could efficiently enhance the quercetin uptake and increase the intracellular accumulation in cancer cells, implying the great potential of functionalized nickel nanoparticles in target cancer therapy.

关键词： Nickel nanoparticles Leukemia cancer cells Quercetin Electrochemical assay

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：