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Smooth Solutions for a Stochastic Hydrodynamical Equation in Heisenberg Paramagnet

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Acta Mathematica Sinica,English Series 2011年第9期27卷 1855-1868页

作者： xue ke pu Bo Ling GUO Yong Qian HAN College of Mathematics and Physics Chongqing University Chongqing 400044 P. R. China Institute of Applied Physics and Computational Mathematics P. O. Box 8009 Beijing 100088 P. R. China

In this article, we consider a stochastic hydrodynamical equation in Heisenberg paramagnet driven by additive noise. We prove the existence and uniqueness of smooth solutions to this equation with difference method.

关键词： Stochastic partial differential equations Heisenberg paramagnet smooth solution difference method

An approach for formation design and flight performance prediction based on aerodynamic formation unit:Energy-saving considerations

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Chinese Journal of Aeronautics 2024年第3期37卷 77-91页

作者： Nanxuan QIAO Tielin MA Xiangsheng WANG Jie WANG Jingcheng FU pu xue School of Aeronautic Science and Engineering Beihang UniversityBeijing 100191China Institute of Unmanned System Beihang UniversityBeijing 100191China key Laboratory of Advanced Technology of Intelligent Unmanned Flight System Ministry of Industry and Information TechnologyBeijing 100191China School of Transportation Science and Engineering Beihang UniversityBeijing 102206China Beijing Institute of Space Long March Vehicle Beijing 100076China

The performance improvement of swarm drones through aerodynamic shape optimization may be challenging due to folded size constraints imposed by the specific launch ***,fixed-wing aircraft swarms can benefit from formation flight in terms of energy *** study introduces the concept of the"aerodynamic formation unit",which consists of two or three aircraft that form an inseparable unit of the *** the Unmanned Aerial Vehicle(UAV)distribution and wingtip vortex interference in the formation,two typical aerodynamic formation units are optimized by the variable-fidelity aerodynamic optimization method based on space *** aerodynamic characteristics of the formation UAVs that affect flight performance,such as lift-to-drag ratio(L/D ratio)and static stability are analyzed by Computational Fluid Dynamics(CFD)*** L/D ratio(cruising condition)of the following aircraft can be increased by 22.8%and 57.5%in the optimal units that involve two and three aircraft ***,this study conducts several CFD simulations for multi-aircraft formations formed by the units,which show that the average L/D ratio of the formation can be improved by more than 19%.These results verify the feasibility and effectiveness of the"aerodynamic formation unit"concept and the optimization framework for formation parameters.

关键词： Formation flight CFD Aerodynamic formation unit Wingtip vortices Foldable tandem-wing aircraft

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Laser-Induced Methanol Decomposition for Ultrafast Hydrogen Production

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Research 2024年第1期2023卷 131-137页

作者： Weiwei Cao Yinwu Li Bo Yan Zhiping Zeng pu Liu Zhuofeng ke Guowei Yang State key Laboratory of Optoelectronic Materials and Technologies Nanotechnology Research CenterSun Yat-sen UniversityGuangzhou 510275P.R.China School of Materials Science and Engineering Sun Yat-sen UniversityGuangzhou 510275P.R.China

Methanol(CH_(3)OH)is a liquid hydrogen(H_(2))source that effectively releases H_(2) and is convenient for *** thermocatalytic CH_(3)OH reforming reaction is used to produce H_(2),but this process needs to undergo high reaction temperature(e.g.,200℃)along with a catalyst and a large amount of carbon dioxide(CO_(2))*** photocatalysis and photothermal catalysis under mild conditions are proposed to replace the traditional thermal catalysis to produce H_(2) from CH_(3)OH,they still inevitably produce CO_(2) emissions that are detrimental to carbon ***,we,for the first time,report an ultrafast and highly selective production of H_(2) without any catalysts and no CO_(2) emission from CH_(3)OH by laser bubbling in liquid(LBL)at room temperature and atmospheric pressure.

关键词： catalysis reforming replace

An Integral Method for Solving Dynamic Equations with Fluid–Solid Coupling

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Acta Mechanica Solida Sinica 2024年第1期37卷 99-108页

作者： Xin Zhang Jie Liu pu xue Shuowen Yan Yahao Xu M.S.Zahran School of Aeronautics Northwestern Polytechnical UniversityXi'an 710072China School of Mechatronical Engineering Beijing Institute of TechnologyBeijing 100081China Department of Civil Engineering Military Technical CollegeCairo 11435Egypt

In this work,a new methodology is presented to mainly solve the fluid–solid interaction(FSI)*** methodology combines the advantages of the Newmark precise integral method(NPIM)and the dual neural network(DNN)*** NPIM is employed to modify the exponential matrix and loading vector based on the DNN integral *** involves incorporating the basic assumption of the Newmark-βmethod into the dynamic equation and eliminating the acceleration term from the dynamic equilibrium *** a result,the equation is reduced to a first-order linear equation ***,the PIM is applied to integrate the system step by step within the *** DNN method is adopted to solve the inhomogeneous term through fitting the integrand and the original function with a pair of neural networks,and the integral term is solved using the Newton–Leibniz *** examples demonstrate that the proposed methodology significantly improves computing efficiency and provides sufficient precision compared to the DNN *** is particularly evident when analyzing large-scale structures under blast loading conditions.

关键词： Newmark precise integral method(NPIM) Dual neural networks(DNN) Fluid-solid interaction(FSI) Dynamic time-history analysis Blast loading

A Robust N-Terminal Pro-Brain Natriuretic Peptide Assay for Clinical Diagnosis of Heart Failure in Elderly Patients

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Journal of Analysis and Testing 2024年第1期8卷 74-82页

作者： xue Gong Jiangling Wu Jiajia Zhang Zhongwei Jiang Yi Wang pu Zhang Engineering Research Center for Biotechnology of Active Substances(Ministry of Education) Chongqing Key Laboratory of Green Synthesis and ApplicationsCollege of ChemistryChongqing Normal UniversityChongqing 401331China Chongqing Research Center for Pharmaceutical Engineering College of PharmacyChongqing Medical UniversityChongqing 400016China Department of Clinical Laboratory University Town Hospital of Chongqing Medical UniversityChongqing 401331China

Heart failure(HF)is a clinical hallmark of cardiovascular syndrome leading to substantial morbidity,repeated hospitalization,and enormous healthcare *** elderly populations continue to increase,biomarker-guided diagnosis and treatment for age-related cardiac decline have become *** evidence demonstrates that N-terminal proBNP(NT-proBNP)can provide a unique window into the diagnosis and risk stratification with ***,a simple yet robust aptasensor is developed for on-site recognizing the NT-proBNP by its targeting aptamer,thus achieving the accurate diagnosis of *** aptasensing system is prepared by absorbing the fluorophore-labeled aptamer strand onto the graphene oxide(GO),leading to efficient quenching without possible off-site signal *** aptamer strand can specifically identify target NT-proBNP molecules via a versatile conformational transformation,resulting in the desorption of the aptamer-NTproBNP complexes from GO and re-generation fluorescence signal,thus allowing sensitive detection of NT-proBNP in 37 clinical blood *** advantage of the high specificity of aptamer-guaranteed recognitions of NT-proBNP,this aptasensor system readily achieves better diagnostic performance for HF than commercially adopted chemiluminescence immunoassay(Siemens,CLIA)in hospitals in terms of accuracy(89.2%vs 83.8%),specificity(89.5%vs 84.2%),and positive predictive value(88.9%vs 83.3%).This work provides a stable option for the diagnosis and treatment of elderly HF-related diseases inclinics.

关键词： NT-proBNP Graphene oxide Aptamer Heart failure Clinical diagnosis

维普期刊数据库

Stable carbon isotope composition and intrinsic water use efficiency in plants along an altitudinal gradient on the eastern slope of Yulong Snow Mountain, China

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Ecological Processes 2024年第2期13卷 218-230页

作者： Feng Jiang Tao pu Zi-Jing xue Yan-Wei Ma Xiao-Yi Shi Fu-Xi Shi College of Geography and Environmental Sciences Zhejiang Normal University Yulong Snow Mountain Glacier and Environment Observation and Research Station/State key Laboratory of Cryospheric Sciences Northwest Institute of Eco-Environment and ResourcesChinese Academy of Sciences key Laboratory of National Forestry and Grassland Administration on Forest Ecosystem Protection and Restoration of Poyang Lake Watershed College of Forestry Jiangxi Agricultural University

Background Stable carbon isotope composition(δ13Cp) can be used to estimate the changes in intrinsic water use efficiency（iWUE） in plants,which helps us to better understand plants' response strategies to climate *** study focused on the variations in δ13Cpand iWUE for the different life-form plants（i.e.,herbs,shrubs,and trees）along an altitudinal gradient（3300,3600,3900,4100,4300,and 4500 m） on the eastern slope of Yulong Snow Mountain,southeastern margin of the Qinghai-Tibet *** response mechanisms of δ13Cpand iWUE for different life-form plants to altitude were thoroughly analyzed in this mountain *** The δ13Cpvalues of plants on the eastern slopes of Yulong Snow Mountain ranged from-30.4‰to-26.55‰,with a mean of-28.02‰,indicating a dominance of *** δ13Cpand iWUE values varied among different life-form plants in the order of herbs> shrubs> trees,particularly in 3600,3900,and 4300 ***δ13Cpand iWUE values for herbs and shrubs increased with altitude and were mainly controlled by air *** two parameters for trees exhibited a trend of initial decrease followed by an increase with *** 3900 m,the δ13Cpand iWUE values decreased with altitude,influenced by soil ***,above 3900 m,the two parameters increased with altitude,mainly regulated by air *** addition,iWUE was positively correlated with leaf P content but negatively correlated with leaf N:P ratio,especially for herbs and trees,suggesting that P plays a key role in modulating iWUE in this *** The diffe rentiated responses of water availability for different life-form plants to a higher altitudinal gradient are regulated by air temperature,soil moisture,and leaf P content in the Yulong Snow *** results provide valuable insights into understanding the wate r-carbon relationships in high-altitude ecosystems.

关键词： Stable carbon isotope Water use efficiency Altitude Life form Yulong Snow Mountain

Weakened tanning ability is an important mechanism for evolutionary skin lightening in East Asians

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Journal of Genetics and Genomics 2024年第7期51卷 703-713页

作者： Youwei pu Siyu pu Yanyan Chen Qinghong Kong Xuyang Liu Qi Zhao ke Xu Jiuming Liu Mengyuan Li Xiaoyu Xu Xiaoyang Qiao Bing Su Jing Chen Zhaohui Yang Tianjian Laboratory of Advanced Biomedical Sciences Academy of Medical ScienceZhengzhou UniversityZhengzhouHenan 450052China Department of Pediatric Surgery and Laboratory of Pediatric Surgery West China HospitalSichuan UniversityChengduSichuan 610041China Guizhou Provincial College-based key Lab for Tumor Prevention and Treatment with Distinctive Medicines Zunyi Medical UniversityZunyiGuizhou 563000China Yunnan key Laboratory of Primate Biomedical Research Institute of Primate Translational MedicineKunming University of Science and TechnologyKunmingYunnan 650500China State key Laboratory of Genetic Resources and Evolution Kunming Institute of ZoologyChinese Academy of SciencesKunmingYunnan 650223China Center for Excellence in Animal Evolution and Genetics Chinese Academy of SciencesKunmingYunnan 650223China

The evolution of light-skin pigmentation among Eurasians is considered as an adaptation to the high-latitude *** Asians are ideal populations for studying skin color evolution because of the complex environment of East ***,we report a strong selection signal for the pigmentation gene phenylalanine hydroxylase(PAH)in light-skinned Han Chinese *** intron mutation rs10778203 in PAH is enriched in East Asians and is significantly associated with skin color of the back of the hand in Han Chinese males(Pker ultraviolet radiation response in A375 cells and zebrafish ***,rs10778203 decreases melanin production in transgenic zebrafish embryos after ultraviolet B(UVB)***,PAH is a potential pigmentation gene that regulates skin tanning *** selection has enriched the adaptive allele,resulting in weakened tanning ability in East Asians,suggesting a unique genetic mechanism for evolutionary skin lightening in East Asians.

关键词： East Asians PAH Skin pigmentation Natural selection Genetic adaptation

Two-Stage Approach for Targeted Knowledge Transfer in Self-Knowledge Distillation

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IEEE/CAA Journal of Automatica Sinica 2024年第11期11卷 2270-2283页

作者： Zimo Yin Jian pu Yijie Zhou Xiangyang xue the School of Computer Science Fudan University the Institute of Science and Technology for Brain Inspired Intelligence Fudan University IEEE

Knowledge distillation(KD) enhances student network generalization by transferring dark knowledge from a complex teacher network. To optimize computational expenditure and memory utilization, self-knowledge distillation(SKD) extracts dark knowledge from the model itself rather than an external teacher network. However, previous SKD methods performed distillation indiscriminately on full datasets, overlooking the analysis of representative samples. In this work, we present a novel two-stage approach to providing targeted knowledge on specific samples, named two-stage approach self-knowledge distillation(TOAST). We first soften the hard targets using class medoids generated based on logit vectors per class. Then, we iteratively distill the under-trained data with past predictions of half the batch size. The two-stage knowledge is linearly combined, efficiently enhancing model performance. Extensive experiments conducted on five backbone architectures show our method is model-agnostic and achieves the best generalization ***, TOAST is strongly compatible with existing augmentation-based regularization methods. Our method also obtains a speedup of up to 2.95x compared with a recent state-of-the-art method.

关键词： Cluster-based regularization iterative prediction refinement model-agnostic framework self-knowledge distillation (SKD) two-stage knowledge transfer

Neuroprotective Effect and Mechanism of Tanreqing Injection on Ischemic Stroke:Insights from Network Pharmacology and in vivo Experiments

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Chinese Journal of Integrative Medicine 2024年第8期30卷 713-720页

作者： LI Zhong-hao pu Xiao-qi LI Sha-sha DONG Xiao-ke ZHANG Guo-qiang WANG Yu LIU Jin-min Department of Emergency China-Japan Friendship HospitalBeijing100029China Department of Neurology Beijing University of Chinese Medicine Dongfang HospitalBeijing100078China Department of Radiology China-Japan Friendship HospitalBeijing100029China Graduate School Beijing University of Chinese MedicineBeijing100029China

Objective To explore the neuroprotective effects and mechanism of Tanreqing Injection(TRQ)on treating ischemic stroke based on network pharmacology and in vivo experimental *** The chemical compounds of TRQ were retrieved based on published data,with targets retrieved from pubChem,Therapeutic Target Database and *** visualization and analysis were performed using Cytoscape,with protein-protein interaction networks derived from the STRING *** analysis was performed using Kyoto Encyclopedia of Genes Genomes pathway and Gene Ontology *** in vivo experiments,the middle cerebral artery occlusion(MCAO)model was *** volume was determined by 2,3,5-triphenyltetrazolium hydrochloride staining and protein expressions were analyzed by Western *** docking was performed to predict ligand-receptor *** We screened 81 chemical compounds in TRQ and retrieved their therapeutic *** the targets,116 were therapeutic targets for *** enrichment analysis showed that the apelin signaling pathway was a key pathway for ischemic ***,in in vivo experiment we found that administering with intraperitoneal injection of 2.5 mL/kg TRQ every 6 h could significantly reduce the infarct volume of MCAO rats(P<0.05).In addition,protein levels of the apelin receptor(APJ)/phosphatidylinositol 3-kinase(PI3K)/protein kinase B(AKT)pathway were increased by TRQ(P<0.05).In addition,41 chemical compounds in TRQ could bind to *** The neuroprotective effect of TRQ may be related to the APJ/PI3K/AKT signaling ***,further studies are needed to confirm the findings.

关键词： Tanreqing Injection Chinese medicine ischemic stroke middle cerebral artery occlusion quantitative estimate of drug-likeness