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Inflammatory myofibroblastic tumor after breast prosthesis:A case report and literature review

World Journal of Clinical Cases 2022年第4期10卷 1432-1440页

作者： Peng Zhou Yi-hao Chen Jiang-hao Lu Chun-Chun Jin Xiao-Hong Xu xue-hao gong Department of Ultrasound Shenzhen Second People’s HospitalThe First Affiliated Hospital of Shenzhen UniversityShenzhen 518035Guangdong ProvinceChina Graduate School Guangdong Medical UniversityZhanjiang 524023Guangdong ProvinceChina Department of Ultrasound Guangdong Medical University Affiliated HospitalZhanjiang 524001Guangdong ProvinceChina

BACKGROUND Inflammatory myofibroblastic tumors(IMTs)are defined as tumors composed of differentiated myofibroblastic spindle cells,usually accompanied by numerous plasma cells and lymphocytes,and classified as intermediate(occasionally metastatic)by the World Health *** pathogenesis and biological behavior have not yet been *** IMT is extremely rare,and prosthesis implantation combined with IMT has not been *** study reports a case of IMT following resection of a malignant phyllodes tumor of the left breast and implantation of a *** SUMMARY A 41-year-old female presented to our hospital with a mass in the left breast for 3 *** patient had undergone resection of a large mass in her left breast pathologically diagnosed as a malignant phyllodes tumor and implantation of a prosthesis five years *** examination revealed an oval mass in the left breast,and the patient underwent left breast mass resection and prosthesis *** microscopy revealed the spindle cells to be diffusely proliferated,with a large number of neutrophils,lymphocytes,and plasma cell *** staining revealed that the spindle cells were partially positive for smooth muscle actin,which is positive for BCL-2 and cluster of differentiation(CD)99 but were negative for anaplastic lymphoma kinase,cytokeratin,S-100 protein,desmin,and *** final diagnosis was *** recurrence or metastasis was observed during the 5-year postoperative *** Prosthesis implantation may be one of the causes of IMT,but further investigation is necessary to prove it.

关键词： Inflammatory myofibroblastic tumor Breast Prosthesis Ultrasonography Surgery Case report

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Spontaneous internal carotid artery pseudoaneurysm complicated with ischemic stroke in a young man:A case report and review of literature

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World Journal of Clinical Cases 2022年第22期10卷 8025-8033页

作者： Yu-Lin Zhong Jia-Ping Feng Hui Luo xue-hao gong Zhang-Hong Wei Department of Ultrasound The Second Clinical College of Jinan UniversityShenzhen People's HospitalShenzhen 518020Guangdong ProvinceChina Department of Ultrasound The First Affiliated Hospital of Southern University of Science and TechnologyShenzhen People's HospitalShenzhen 518020Guangdong ProvinceChina Department of Ultrasound Shenzhen Second People’s HospitalThe First Affiliated Hospital of Shenzhen UniversityShenzhen 518035Guangdong ProvinceChina Graduate School Guangzhou Medical UniversityGuangzhou 510180Guangdong ProvinceChina

BACKGROUND Carotid artery pseudoaneurysm(PSA)is infrequently encountered in clinical *** carotid artery(ICA)PSA complicated with ischemic stroke is *** are typically caused by iatrogenic injury,trauma,or *** underlying mechanisms of spontaneous PSA formation are not well *** report a healthy young man who presented with stroke as a complication of spontaneous PSA of the left *** SUMMARY A 30-year-old man working as a ceiling decoration worker was hospitalized due to sudden-onset speech disorder and right lower extremity *** history was *** computed tomography revealed ischemic *** subtraction angiography showed a left ICA PSA with mild *** patient was conservatively managed with oral anticoagulation and antiplatelet *** recovered well and was *** patient was in good condition during *** The occupational history of patient should be taken into consideration while evaluating the etiology of spontaneous ICA PSA in young people with stroke.

关键词： Pseudoaneurysm Carotid artery injury Ischemic stroke Case report

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Recent Advancements in the Optimization Capacity Configuration and Coordination Operation Strategy of Wind-Solar Hybrid Storage System

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Energy Engineering 2025年第1期122卷 285-306页

作者： Hongliang hao Caifeng Wen Feifei xue haoQiu Ning Yang Yuwen Zhang Chaoyu Wang Edwin E.Nyakilla Department of New Energy Storage Peking University Ordos Research Institute of EnergyOrdos017010China School of Energy and Power Engineering Inner Mongolia University of TechnologyHohhot010080China Key Laboratory of Wind Energy and Solar Energy Utilization Technology Inner Mongolia University of TechnologyHohhot010051China

Present of wind power is sporadically and cannot be utilized as the only fundamental load of energy *** paper proposes a wind-solar hybrid energy storage system(HESS)to ensure a stable supply grid for a longer period.A multi-objective genetic algorithm(MOGA)and state of charge(SOC)region division for the batteries are introduced to solve the objective function and configuration of the system capacity,***/Simulink was used for simulation *** optimization results show that for a 0.5 MW wind power and 0.5 MW photovoltaic system,with a combination of a 300 Ah lithium battery,a 200 Ah lead-acid battery,and a water storage tank,the proposed strategy reduces the system construction cost by approximately 18,000 ***,the cycle count of the electrochemical energy storage systemincreases from4515 to 4660,while the depth of discharge decreases from 55.37%to 53.65%,achieving shallow charging and discharging,thereby extending battery life and reducing grid voltage fluctuations *** proposed strategy is a guide for stabilizing the grid connection of wind and solar power generation,capability allocation,and energy management of energy conservation systems.

关键词： Electric-thermal hybrid storage modal decomposition multi-objective genetic algorithm capacity optimization allocation operation strategy

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Modular assembly of complex C-alkyl glycoside enabled via cooperative NHC and photoredox catalysis

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Science China Chemistry 2025年

作者： Rui-Qiang Jiao Ming Li Xi Chen Mei-Ze Xu Tian Ding Xiao-Ping gong Zhuo-Mei Li xue-Yuan Liu Yong-Min Liang State Key Laboratory of Applied Organic Chemistry Lanzhou University College of Chemistry and Chemical Engineering Northwest Normal University

C-Alkyl glycosides are found in natural products and are indispensable in drug development programs,owing to their diverse range of medicinal ***-component reactions involving glycosyl radical addition are well documented and proved efficient for the C-alkyl glycosides ***,multicomponent reactions for the rapid and controllable construction of structurally diversified C-alkyl glycosides in a single step remains a significant challenge due to the issues associated with balancing reactivity,compatibility,and ***,we report an NHC and photoredox co-catalyzed three-component method to access complex and valuable C-alkyl *** protocol exhibits broad substrate scope and excellent chemoand ***,nine types of sugars are compatible with this *** addition,the generality of this catalytic strategy was further highlighted by the potential for scalable production,the feasibility of further modifications of the products and its successful application in the late-stage functionalization of pharmaceutical skeletons.

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Enhanced subacute ischemic stroke treatment via multistage drug delivery system design for combination therapy

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Science China Chemistry 2025年

作者： Xihan Xu Juan-Juan Li Jiamin Li Hui-Yan Zhang Yilin Qi Bing-Sen Shi Tianqi Li Shan-Shan Su Weitao Zhao Chang Chen Zhongying gong Huiyu Liu Ke-Rang Wang Dong-Sheng Guo xue xue State Key Laboratory of Medicinal Chemical Biology College of Pharmacy Nankai University College of Chemistry State Key Laboratory of Elemento-Organic Chemistry Key Laboratory of Functional Polymer Materials (Ministry of Education) Frontiers Science Center for New Organic Matter Collaborative Innovation Center of Chemical Science and EngineeringNankai University College of Chemistry and Materials Science State Key Laboratory of New Pharmaceutical Preparations and Excipients Key Laboratory of Medicinal Chemistry and Molecular Diagnosis (Ministry of Education) Key Laboratory of Chemical Biology of Hebei Province Hebei Research Center of the Basic Discipline of Synthetic Chemistry Hebei University Department of Neurology Tianjin First Central Hospital School of Medicine Nankai University Beijing Advanced Innovation Center for Soft Matter Science and Engineering State Key Laboratory of Organic-Inorganic Composites Beijing Laboratory of Biomedical Materials Bionanomaterials & Translational Engineering Laboratory Beijing Key Laboratory of BioprocessBeijing University of Chemical Technology

The management of acute ischemic stroke remains challenging due to its abrupt onset and the narrow treatment window,resulting in high rates of disability and *** therapy for neuroprotection and neurorepair strategies provided new hopes for subacute stroke *** we designed a multistage nanodelivery system that matches the unique microenvironment of the subacute phase of stroke,which utilizes calixarene as a building block to effectively load the neuroprotective drug *** calixarene is designed with glycosidic linkages targeting the glucose transporter 1 (GLUT1)on the blood-brain barrier (BBB) and azo bonds that are responsive to hypoxic ***,the decomposed calixarene molecules themselves possess intrinsic bio-activation to modulate inflammatory responses,achieving a multistage therapeutic approach that transitions from targeting to release and finally to *** approach combines anti-inflammation and neuroprotection,providing a multi-level treatment *** system was validated in a rat model of permanent middle cerebral artery occlusion (pMCAO),demonstrating that intravenous administration of the nanodelivery system repairs brain damage and improves motor function 24 h post-pMCAO *** work offers a precise and integrative strategy for stroke patients missing the acute therapy window to improve functional recovery and enhance the effect of comprehensive treatment.

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Ko Kuei Chen:a pioneer of modern pharmacological research in China

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Protein & Cell 2023年第5期14卷 315-317页

作者： Huan Liu Zhaoqi Liu xue gong hao Cheng University of Science and Technology of China Hefei 230026China State Key Laboratory of Virology Wuhan 430072China Institute of Microbiology Chinese Academy of SciencesBeijing 100101China

Ko Kuei Chen(陈克恢,1898–1988)(Fig.1)was a pharmacologist who ceaselessly strove for medical research all his *** was a pioneer of modern pharmacological research in Chinese medicine(Qian,2014).He systematically studied the pharmacological action of ephedrine and published the first paper on this topic in the *** discovered that injecting sodium nitrite and sodium thiosulfate intravenously could effectively treat acute cyanide poisoning(Chen and Rose,1952).He isolated cinobufagin and cinobufotoxin from Ch’an Su,the dried venom of the Chinese *** research in pharmacology enriched the treasure trove of *** Kuei Chen was a pioneer of pharmacology in Chinese medicine,and his research had epoch-making significance in the *** pharmacological research on ephedrine set a milestone in the world medicine history.

关键词： pioneer dried epoch

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Recent progress in metal-organic frameworks(Part II—material application)

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Science China Chemistry 2025年

作者： Jiandong Pang Wentao Jiang xue-Wen Zhang hao-Long Zhou Yuxiu Sun Wei gong Bin Wang Fuyin Ma Linwei He Long Chen Qiang Chen He-Qi Zheng Yuanjing Cui Wen-Jie Shi Chao Zhang Mei Wang Yue-Biao Zhang Jie-Peng Zhang Chongli Zhong Yong Cui Shuao Wang Jian-Rong Li Guodong Qian Tong-Bu Lu Huan Pang Xian-He Bu Institute for New Energy Materials and Low Carbon Technologies School of Materials Science and Engineering Tianjin University of Technology School of Chemistry and Chemical Engineering Yangzhou University School of Materials Science and Engineering Nankai University School of Physical Science and Technology ShanghaiTech University MOE Key Laboratory of Bioinorganic and Synthetic Chemistry GBRCE for Functional Molecular Engineering School of Chemistry IGCMESun Yat-sen University Department of Chemistry Shantou University School of Chemical Engineering and Technology Tiangong University School of Chemistry and Chemical Engineering Shanghai Jiao Tong University State Key Laboratory of Radiation Medicine and Protection School for Radiological and Interdisciplinary Sciences Soochow University College of Materials Science & Engineering Beijing University of Technology State Key Laboratory of Silicon and Advanced Semiconductor Materials Cyrus Tang Center for Sensor Materials and ApplicationsSchool of Materials Science & Engineering Zhejiang University

As a class of functional crystalline porous materials, metal-organic frameworks(MOFs) gained rapid development in the past three decades and a large number of MOFs with ordered structures, high surface areas, and functionalized channels have been investigated. MOFs and MOF-derived/composite materials show great potential in many application fields. In this review, we discussed the main applications of MOFs and MOF-derived/composite materials in small molecule storage, separation, luminescence, sensing, multitype catalysis, and energy storage. In addition, challenges and problems in the future research of MOFsrelated fields are also discussed.

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Unique adsorption behaviors of NO and O_2 at hydrogenated anatase TiO_2(101)

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Chinese Chemical Letters 2018年第6期29卷 765-768页

作者： Fei Li Wen-hao Huang xue-Qing gong Key Laboratory for Advanced Materials Centre for Computational Chemistry and Research Institute of Industrial Catalysis School of Chemistry and Molecular Engineering East China University of Science and Technology

Titanium dioxide（TiO2） is one of the most widely studied transition metal oxides, especially for its unique performances in heterogeneous photocatalysis. Different phases of TiO2 have been found to exhibit different photo-activities, though the origins are still not fully understood. In this work, we use the density functional theory（DFT） calculations, corrected by on-site Coulomb and long-range dispersion interactions, to study the adsorptions of nitric oxide（NO） and oxygen（O2） molecules on the clean and hydrogenated anatase TiO2（101） surfaces. We also compare the detailed calculated results regarding their structural, energetic and electronic properties with those obtained at rutile TiO2（110）. It has been found that the behaviors of the surface localized electrons being transferred from adsorbed H, as well as the adsorption behaviors of NO and O2 are quite different at the two surfaces, which can be attributed to their characteristic local bonding structures around the surface hydroxyl. These results may also help explain the different photocatalytic activities of these two main facets of anatase and rutile TiO2

关键词： Anatase TiO2(101) Rutile TiO2(110) Surface adsorptions Surface hydroxyls Localized electrons Photocatalysis Density functional theory

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The modified Casson's equation and its application to pipe flows of shear-thickening fluid

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Acta Mechanica Sinica 2005年第3期21卷 243-248页

作者： hao xue The Research Association of Oriental Medical Engineering 2015 Hering Ave. Bronx NY 10461 USA

A few additional data from our previous experiments were plotted to emphasize the shear-thickening behavior ofdeoxy sickle erythrocyte （SS） suspension. A constitutive equation （named as FX equation） was developed and applied to a cylindrical pipe flow of a shear-thickening fluid. A blunt velocity profile and its volume flow rate were calculated. The flow was non-viscous （potential） in the central part of the pipe （i.e. the central core or the central plug-flow）, and became more and more viscous towards the wall of the pipe after a specific radial distance, which was determined by a critical shear rate of γF （named as Fung＇s shear rate）. Furthermore, combining the FX equation with the original Casson＇s equation, the author obtained a modified Casson＇s equation by introducing γF.

关键词： Sickle erythrocyte Fung's shear rate FX equation Potential plug Casson's plot

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2D Layered Double Hydroxide Nanosheets and Their Derivatives Toward E cient Oxygen Evolution Reaction

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Nano-Micro Letters 2020年第7期12卷 89-120页

作者： xueyi Lu Hairong xue hao gong Mingjun Bai Daiming Tang Renzhi Ma Takayoshi Sasaki International Center for Materials Nanoarchitectonics(WPI-MANA) National Institute for Materials Science(NIMS)TsukubaJapan

Layered double hydroxides(LDHs)have attracted tremendous research interest in widely spreading *** notably,transition-metal-bearing LDHs are expected to serve as highly active electrocatalysts for oxygen evolution reaction(OER)due to their layered structure combined with versatile ***,reducing the thickness of platelet LDH crystals to nanometer or even molecular scale via cleavage or delamination provides an important clue to enhance the *** this review,recent progresses on rational design of LDH nanosheets are reviewed,including direct synthesis via traditional coprecipitation,homogeneous precipitation,and newly developed topochemical oxidation as well as chemical exfoliation of parent LDH *** addition,diverse strategies are introduced to modulate their electrochemical activity by tuning the composition of host metal cations and intercalated counter-anions,and incorporating dopants,cavi-ties,and single *** particular,hybridizing LDHs with conductive components or in situ growing them on conductive substrates to produce freestanding electrodes can further enhance their intrinsic catalytic activity.A brief discussion on future research directions and prospects is also summarized.

关键词： Layered double hydroxides Nanosheets Derivatives Catalysts Oxygen evolution reaction

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