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Mechanism of selective laser trabeculoplasty:a systemic review

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International Journal of Ophthalmology(English edition) 2024年第5期17卷 963-968页

作者： yu-feng Chen Wen Zeng Department of Ophthalmology Zhongnan Hospital of Wuhan UniversityWuhan 430071Hubei ProvinceChina

Although selective laser trabeculoplasty(SLT)is a recognized method for the treatment of glaucoma,the exact changes in the target tissue and mechanism for its intraocular pressure lowing effect are still *** purpose of this review is to summarize the potential mechanisms of SLT on trabecular meshwork both in vivo and in vitro,so as to reveal the potential mechanism of *** may induce immune or inflammatory response in trabecular meshwork(TM)induced by possible oxidative damage etc,and remodel extracellular *** may also induce monocytes to aggregate in TM tissue,increase Schlemm’s canal(SC)cell conductivity,disintegrate cell junction and promote permeability through autocrine and paracrine *** provides a theoretical basis for SLT treatment in glaucoma.

关键词： mechanisms selective laser trabeculoplasty glaucoma trabecular meshwork

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当代中国马克思主义经济学的流派

经济纵横 2009年第1期 31-40页

作者：薛宇峰上海财经大学财经研究所上海200433

21世纪是中国马克思主义经济学思想和理论之成熟、发展和创新的时代。繁荣与发展中国经济学,需要创立不同的流派,马克思主义经济学内部也应形成不同的流派,这是学术繁荣的重要标志之一。因此,要实现中国马克思主义经济学的创新和发展,... 详细信息

21世纪是中国马克思主义经济学思想和理论之成熟、发展和创新的时代。繁荣与发展中国经济学,需要创立不同的流派,马克思主义经济学内部也应形成不同的流派,这是学术繁荣的重要标志之一。因此,要实现中国马克思主义经济学的创新和发展,不能不研究中国马克思主义经济学中的不同流派和学说的源渊与形成历史、观点与分析方法及理论体系。当前,我国在发展和创新马克思主义经济学过程中,已形成马克思主义经济学八大流派:正统的马克思主义经济学创新流派;新马克思主义经济学综合流派;经典的马克思主义经济学文本流派;马克思主义生态经济学流派;演化的马克思主义经济学流派;数理马克思主义经济学流派;转型经济理论的马克思主义经济学流派;后凯恩斯主义的马克思主义经济学流派。

关键词：当代中国马克思主义经济学创新流派

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中国农村收入分配差距的现状和空间分布特征

财经研究 2005年第5期31卷 133-144页

作者：薛宇峰上海财经大学财经研究所上海200433

文章采用统计分析方法和基尼系数作为收入分配的测度指标,并以此研究中国农村各个省市间收入分配的差距。文章还通过提出基尼系数改变率,对全国农村各省市的收入分配不平等的变化倾向作了比较。另外,文章还对影响中国农村居民收入增长... 详细信息

文章采用统计分析方法和基尼系数作为收入分配的测度指标,并以此研究中国农村各个省市间收入分配的差距。文章还通过提出基尼系数改变率,对全国农村各省市的收入分配不平等的变化倾向作了比较。另外,文章还对影响中国农村居民收入增长的因素进行了定量分析。其分析结论对解决“三农问题”,帮助中央政府制定有关对策是十分必要的和有价值的。

关键词：收入分配基尼系数改变率收入因素贡献度区域差异

Association of Human Whole-blood NAD+Levels with Nabothian Cyst

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Biomedical and Environmental Sciences 2024年第5期37卷 471-478页

作者： XU Ling WANG yue Xuan WANG Wei FAN xue CHEN xue yu ZHOU Tian yun LIU yu He yu Ye YANG Fan JU Zhen yu ZHOU Yong WANG Deng Liang Clinical Research Institute Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai 200080China NHC Key Lab of Reproduction Regulation Shanghai Engineering Research Center of Reproductive Health Drugs and DevicesShanghai Institute for Biomedical and Pharmaceutical TechnologiesShanghai 200237China Department of Applied Statistics Johannes Kepler University LinzLinz 4040Austria Hematology Center Beijing Key Laboratory of Pediatric Hematology OncologyNational Key Discipline of Pediatrics(Capital Medical University)Key Laboratory of Major Diseases in ChildrenMinistry of EducationBeijing Children's HospitalCapital Medical UniversityNational Center for Children's HealthBeijing 100045China Department of Biostatistics School of Public HealthCheeloo College of MedicineShandong UniversityJinan 250012ShandongChina Clinical Medicine School of Basic MedicineShanghai Medical College Fudan UniversityShanghai 200032China Department of Biochemistry and Molecular Biology Hengyang Medical SchoolUniversity of South ChinaHengyang 421001HunanChina Administrative Office Total Quality Management OfficeTotal Quality Management InstituteShanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai 200080China The First Affiliated Hospital of Jinan University Institute of Aging and Regenerative MedicineJinan UniversityJinan 510632GuangzhouChina Department of Scientific Research The First Affiliated Hospital of Huzhou UniversityHuzhou 313000ZhejiangChina Department of Neurosurgery Neurosurgery Research InstituteThe First Affiliated HospitalFujian Medical UniversityFuzhou 350005FujianChina Department of Neurosurgery Binhai Branch of National Regional Medical CenterThe First Affiliated HospitalFujian Medical UniversityFuzhou 350209FujianChina Fujian Provincial Institutes of Brain Disorders and Brain Sciences The First Affiliated HospitalFujian Medical UniversityFuzhou 350005FujianChina Fujian Provincial Clinical Research Center for Neurological

Objective Little is known about the association between whole-blood nicotinamide adenine dinucleotide(NAD^(+))levels and nabothian *** study aimed to assess the association between NAD^(+)levels and nabothian cysts in healthy Chinese *** Multivariate logistic regression analysis was performed to analyze the association between NAD^(+)levels and nabothian *** The mean age was 43.0±11.5 years,and the mean level of NAD^(+)was 31.3±5.3μmol/*** cysts occurred in 184(27.7%)participants,with single and multiple cysts in 100(15.0%)and84(12.6%)participants,*** total nabothian cyst prevalence gradually decreased from37.4%to 21.6%from Q1 to Q4 of NAD^(+)and the prevalence of single and multiple nabothian cysts also decreased across the NAD^(+)*** compared with the highest NAD^(+)quartile(≥34.4μmol/L),the adjusted odds ratios with 95%confidence interval of the NAD^(+)Q1 was 1.89(1.14–3.14)for total nabothian *** risk of total and single nabothian cysts linearly decreased with increasing NAD^(+)levels,while the risk of multiple nabothian cysts decreased more rapidly at NAD^(+)levels of 28.0 to35.0μmol/***:Low NAD^(+)levels were associated with an increased risk of total and multiple nabothian cysts.

关键词： Nicotinamide adenine dinucleotide Nabothian cyst Female Risk factor

Effect of nourishing Yin and purging fire Chinese herbal mixture on delaying light-induced premature puberty in rats

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Journal of Traditional Chinese Medicine 2024年第1期44卷 95-102页

作者： SUN Yanyan xue yuanyuan SUN Wen WANG Yonghong yu Jian Department of Traditional Chinese Medicine Children's Hospital of Fudan UniversityShanghai 201102China Department of Pediatrics Zibo Central HospitalZibo 255000China

OBJECTIVE:To elucidate the mechanism of the nourishing Yin and purging fire Chinese herbal mixture(NYPF)in delaying light-induced premature puberty in ***:Twenty-one days old female SpragueDawley rats were randomly assigned to normal group(N),long light exposure group(L),NYPF and normal saline group(NS).Rats in the L,NYPF and NS groups were exposed to 16 h:350 lux light/8 h:dark,while rats in the N group were exposed to 12 h:50 lux light/12 h:*** and normal saline was administered to the rats in the NYPF group or NS group,respectively,from day *** rats in every group were sacrificed at 9 *** day 28(P28),on the day when rat's vulva opened in the L group(L-VO),on the day when the first estrous interphase occurred in rats of L group(L-E1),and on the day when the second estrous interphase occurred in rats of L group(L-E2),***:On day 34,all rats in the L group,80%of rats in the NS group,40%of rats in the N group,and 20%of rats in the NYPF group showed complete opening of the *** P28,m RNA level of hypothalamic kisspeptin(Kiss-1)in the L group was significantly higher than that in the N group(P<0.05).The rats in the L and NS groups had significantly lower hypothalamic argininephenylalanine-amide(RFamide)-related peptide 3(RFRP-3)m RNA levels than those in the N group(P<0.05),whereas RFRP-3 m RNA level was significantly higher in the NYPF group than that in the L group(P<0.05).At L-VO,the ovarian index of the L and NS groups was significantly higher than that of the N group(P<0.05)and estradiol(E2)level of the NYPF group was significantly lower than that of the N and NS groups(P<0.05);hypothalamic Kiss-1 m RNA level in the L and NS groups was significantly higher than that in the N and NYPF groups(P<0.05),whereas hypothalamic RFRP-3 m RNA level in the L,NYPF,and NS groups was significantly lower than that in the N group(P<0.05).At L-E1,E2 level of the L and NS groups was significantly higher than that of the N group(P<0.01),wher

关键词： light puberty precocious kisspeptins RFRP-3 melatonin Nourishing Yin and Purging Fire

Which Neighborhoods Have Easier Access to Online Home Delivery Services?A Spatiotemporal Accessibility Analysis in Nanjing,China

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Chinese Geographical Science 2024年第4期34卷 722-738页

作者： KONG yu ZHEN feng ZHANG Shanqi SHEN Lizhen School of Architecture and Urban Planning Nanjing UniversityNanjing 210093China Provincial Engineering Research Center of Smart City Planning and Digital Governance Nanjing 210093China

The rise in online home delivery services(OHDS)has had a significant impact on how urban services are supplied and used in recent *** on the spatial accessibility of OHDS are emerging,but few is known about the temporal dimension of OHDS accessibility as well as the geographic and socioeconomic differences in the spatiotemporal accessibility of *** study measures the spatiotemporal accessibility of four types of OHDS,namely leisure,fresh and convenient,medical,and catering *** geographic and socioeconomic disparities in the spatiotemporal accessibility of these four types of OHDS are then identified using spatial statistical methods and the Kruskal-Wallis test(K-W test).The case study in Nanjing,China,suggests that:1)spatiotemporal accessibility better reflects the temporal variation of OHDS accessibility and avoids overestimation of OHDS accessibility when only considering its spatial dimension.2)The spatiotemporal accessibility of OHDS varies geographically and *** located in the main city or neighborhoods with higher housing prices,higher population density,and higher point of interest(POI)mix have better OHDS spatiotemporal *** study contributes to the understanding of OHDS accessibility from a spatiotemporal perspective,and the empirical insights can assist policymakers in creating intervention plans that take into account variations in OHDS spatiotemporal accessibility.

关键词： online home delivery services(OHDS) spatiotemporal accessibility neighborhoods accessibility differences Nanjing City China

Alignment of Track Oscillations during Tropical Cyclone Rapid Intensification

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Advances in Atmospheric Sciences 2024年第4期41卷 655-670页

作者： Tong XIE Liguang WU Yecheng feng Jinghua yu Key Laboratory of Meteorological Disaster of Ministry of Education Nanjing University of Information Science and TechnologyNanjing 210044China Dept.of Atmospheric and Oceanic Sciences and Institute of Atmospheric Sciences Fudan UniversityShanghai 200438China CMA-FDU Joint Laboratory of Marine Meteorology Shanghai 200438China

Recent studies on tropical cyclone(TC)intensity change indicate that the development of a vertically aligned TC circulation is a key feature of its rapid intensification(RI),however,understanding how vortex alignment occurs remains a challenging topic in TC intensity change *** on the simulation outputs of North Atlantic Hurricane Wilma(2005)and western North Pacific Typhoon Rammasun(2014),vortex track oscillations at different vertical levels and their associated role in vortex alignment are examined to improve our understanding of the vortex alignment during RI of TCs with initial hurricane *** is found that vortex tracks at different vertical levels oscillate consistently in speed and direction during the RI of the two simulated *** the consistent track oscillation reduces the oscillation tilt during RI,the reduction of vortex tilt results mainly from the mean track before *** is also found that the vortex tilt is primarily due to the mean vortex track before and after *** track oscillations are closely associated with wavenumber-1 vortex Rossby waves that are dominant wavenumber-1 circulations in the TC inner-core *** study suggests that the dynamics of the wavenumber-1 vortex Rossby waves play an important role in the regulation of the physical processes associated with the track oscillation and vertical alignment of TCs.

关键词： tropical cyclone rapid intensification vortex tilt Rossby wave

Machine learning in metal-ion battery research: Advancing material prediction, characterization, and status evaluation

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Journal of Energy Chemistry 2024年第3期90卷 191-204,I0006页

作者： Tong yu Chunyang Wang Huicong Yang feng Li Shenyang National Laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016LiaoningChina School of Materials Science and Engineering University of Science and Technology of ChinaShenyang 110016LiaoningChina Department of Physics and Astronomy University of California IrvineIrvineCA92697USA

Metal-ion batteries(MIBs),including alkali metal-ion(Li^(+),Na^(+),and K^(3)),multi-valent metal-ion(Zn^(2+),Mg^(2+),and Al^(3+)),metal-air,and metal-sulfur batteries,play an indispensable role in electrochemical energy ***,the performance of MIBs is significantly influenced by numerous variables,resulting in multi-dimensional and long-term challenges in the field of battery research and performance *** learning(ML),with its capability to solve intricate tasks and perform robust data processing,is now catalyzing a revolutionary transformation in the development of MIB materials and *** this review,we summarize the utilization of ML algorithms that have expedited research on MIBs over the past five *** present an extensive overview of existing algorithms,elucidating their details,advantages,and limitations in various applications,which encompass electrode screening,material property prediction,electrolyte formulation design,electrode material characterization,manufacturing parameter optimization,and real-time battery status ***,we propose potential solutions and future directions for the application of ML in advancing MIB development.

关键词： Metal-ion battery Machine learning Electrode materials Characterization Status evaluation

A hybrid physics-informed data-driven neural network for CO_(2) storage in depleted shale reservoirs

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Petroleum Science 2024年第1期21卷 286-301页

作者： Yan-Wei Wang Zhen-xue Dai Gui-Sheng Wang Li Chen yu-Zhou Xia yu-Hao Zhou College of Construction Engineering Jilin UniversityChangchun130026JilinChina Institute of Intelligent Simulation and Early Warning for Subsurface Environment Jilin UniversityChangchun130026JilinChina School of Energy Resources China University of GeosciencesBeijing100083China Department of Safety Environmental Protection and Quality ManagementShengli OilfieldSinopecDongying257000ShandongChina Key Laboratory of Thermo-Fluid Science and Engineering of MOE School of Energy and Power EngineeringXi'an Jiaotong UniversityXi'an710049ShaanxiChina College of Computer Science and Technology China University of Petroleum(East China)Qingdao266580ShandongChina Department of Physics University of FribourgFribourg1700Switzerland

To reduce CO_(2) emissions in response to global climate change,shale reservoirs could be ideal candidates for long-term carbon geo-sequestration involving multi-scale transport ***,most current CO_(2) sequestration models do not adequately consider multiple transport ***,the evaluation of CO_(2) storage processes usually involves laborious and time-consuming numerical simulations unsuitable for practical prediction and *** this paper,an integrated model involving gas diffusion,adsorption,dissolution,slip flow,and Darcy flow is proposed to accurately characterize CO_(2) storage in depleted shale reservoirs,supporting the establishment of a training *** this basis,a hybrid physics-informed data-driven neural network(HPDNN)is developed as a deep learning surrogate for prediction and *** incorporating multiple sources of scientific knowledge,the HPDNN can be configured with limited simulation resources,significantly accelerating the forward and inversion ***,the HPDNN can more intelligently predict injection performance,precisely perform reservoir parameter inversion,and reasonably evaluate the CO_(2) storage capacity under complicated *** validation and test results demonstrate that the HPDNN can ensure high accuracy and strong robustness across an extensive applicability range when dealing with field data with multiple noise *** study has tremendous potential to replace traditional modeling tools for predicting and making decisions about CO_(2) storage projects in depleted shale reservoirs.

关键词： Deep learning Physics-informed data-driven neural network Depleted shale reservoirs CO_(2)storage Transport mechanisms