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Effects of soil stoichiometry of the CaCO_3/available phosphorus ratio on plant density in Artemisia ordosica communities

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Chinese Science Bulletin 2012年第5期57卷 492-499页

作者： ZHAO xueLai HE XingDong xue PingPing ZHANG Ning WU Wei LI Rong CI HuaCong XU JingJing gao YuBao ZHAO HaLin Colleee of Life Sciences Nankai UniversityTianiin 300071China Cold and Arid Regions Environmental and Engineering Research Institute Chinese Academy of SciencesLanzhou 730000China

In soil, CaCO3 can reduce the availability of phosphorus in arid and semi-arid regions, thereby influencing plant growth. However, the effects of soil stoichiometry of the CaCO3/available phosphorus ratio (CaCO3/AP ratio) on plant density are unknown. In this study, we examined 4 Artemisia ordosica communities located in arid and semi-arid regions, and performed a pot experiment with an orthogonal design to examine the relationships between the soil CaCO3/AP ratio and plant density. The results showed that the soil stoichiometry of the CaCO3/AP ratio had a greater effect on growth of A. ordosica than either CaCO3 or AP as single factor. The influence of the soil CaCO3/AP ratio on density of A. ordosica was related to the climatic zone and the types and/or amplitudes of increases in the soil CaCO3/AP ratio. When the soil CaCO3/AP ratio was within the same amplitude and was less than 2.5, the A. ordosica density increased in the semi-arid region, whereas the density decreased with increasing soil CaCO3/AP ratios in the arid region. In the semi-arid region, when the soil CaCO3/AP ratio was within the same amplitude and the increase in the soil CaCO3 content was greater than the increase in soil AP, the A. ordosica density increased with increasing soil CaCO3/AP ratios. This means that the relationship between the soil CaCO3/AP ratio and the A. ordosica density remained the same. In the arid region, an increase in the soil CaCO3/AP ratio as a result of increased soil CaCO3 content and decreased soil AP resulted in increased density of A. ordosica. Therefore, the relationship between soil CaCO3/AP ratios and density of A. ordosica was altered by these changes in soil chemistry. Thus, the soil stoichiometry of the CaCO3/AP ratio is an important factor affecting the density of A. ordosica in arid and semi-arid regions.

关键词：化学计量学土壤化学种植密度油蒿群落半干旱地区碳酸钙含量 CaCO3含量比例

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一种电动汽车驱动系统扭转振动扭矩梯度控制方法

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汽车电器 2024年第5期 22-25页

作者：王晶刘晓丹郑敏薛双苓张二红江薇廊坊职业技术学院机电工程系河北廊坊065000

本文提出一种电动汽车驱动系统扭转振动扭矩梯度控制方法。该方法引入RBF神经网络计算扭矩变化率梯度限制值,利用扭矩变化率限制值对驱动电机的输出扭矩进行限制,以此防止扭矩突然变大所造成的传动系统各轴段的过度扭转,从根源上消除引... 详细信息

本文提出一种电动汽车驱动系统扭转振动扭矩梯度控制方法。该方法引入RBF神经网络计算扭矩变化率梯度限制值,利用扭矩变化率限制值对驱动电机的输出扭矩进行限制,以此防止扭矩突然变大所造成的传动系统各轴段的过度扭转,从根源上消除引起驱动系统扭转振动的问题。与传统扭转振动控制方法不同,文章提出的控制方法面向实际工程应用,不依赖于车辆简化的二阶质量模型以及车辆参数,避免由于模型及车辆参数精度问题对控制效果造成的不良影响,具有优良的实际工程应用价值。最后,文章通过实车试验的方式对该方法的可行性及有效性进行验证。

关键词：扭转振动驱动电机扭矩梯度电动汽车

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数字化印模技术配合全面护理干预在口腔正畸治疗中的应用

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中国美容医学 2024年第7期33卷 168-171页

作者：罗武香郑佳佳张丽丽薛思妮朱玲玲合肥市口腔医院(安徽医科大学合肥口腔临床学院)正畸一科安徽合肥230000

目的:探究数字化印模技术配合全面护理干预对口腔正畸效果的影响。方法:选取2020年1月-2022年10月笔者科室收治的预采用数字化印模技术制取模型进行口腔正畸的80例患者,按随机数字表法分为观察组和对照组,每组40例。对照组患者给予常规... 详细信息

目的:探究数字化印模技术配合全面护理干预对口腔正畸效果的影响。方法:选取2020年1月-2022年10月笔者科室收治的预采用数字化印模技术制取模型进行口腔正畸的80例患者,按随机数字表法分为观察组和对照组,每组40例。对照组患者给予常规护理干预,观察组患者给予全面护理干预,比较两组正畸疗效、口腔健康相关生活质量量表(Oral health impact profile-14,OHIP-14)评分、自我效能量表(Generalized self-efficacy scale,GSES)评分、患者对矫治的满意度评分、纽卡斯尔护理满意度量表(Newcastle satisfaction with nursing scale,NSNS)评分及治疗期间并发症发生情况。结果:干预6个月后,观察组口腔正畸总有效率高于对照组,OHIP-14评分低于对照组,GSES评分高于对照组,观察组患者对咀嚼功能、固定、舒适性、便捷程度及语言功能的满意度评分高于对照组,观察组患者对护理的满意度高于对照组,观察组治疗期间并发症发生率为10.00%,低于对照组的32.50%,以上指标组间比较差异均有统计学意义(P<0.05)。结论:数字化印模技术配合全面护理干预可以提升口腔正畸患者的整体治疗体验,优化治疗效果,并加强医患之间的沟通与协作,具有积极的临床应用价值。

关键词：数字化印模技术口腔正畸护理干预口腔健康相关生活质量护理满意度

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利用可选择源项分析SGTR事故放射性后果的研究

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核动力工程 2010年第5期31卷 108-112页

作者：郑啸宇黄高峰曹学武上海交通大学机械与动力工程学院上海200240

介绍了可选择源项的基本假设和剂量计算的基本方法,采用一体化核电厂安全分析程序以及美国NRC RG 1.183中定义的放射性源项和方法,评估了900 MW级核电厂发生蒸汽发生器传热管破裂(SGTR)事故后的放射性后果,并计算了主控室、非居住区边... 详细信息

介绍了可选择源项的基本假设和剂量计算的基本方法,采用一体化核电厂安全分析程序以及美国NRC RG 1.183中定义的放射性源项和方法,评估了900 MW级核电厂发生蒸汽发生器传热管破裂(SGTR)事故后的放射性后果,并计算了主控室、非居住区边界和低人口密度区外边界的剂量值。将计算结果与剂量准则进行比较,其结果完全在可接受的范围内。

关键词：蒸汽发生器传热管破裂可选择源项放射性后果

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Protective Effect of Emodin against Lipopolysaccharides-induced Corneal Injury in Rats

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Chinese Medical Sciences Journal 2009年第4期24卷 236-240页

作者： Guo-ling Chen Zhi-yu Liu Jing Wang xue gao Lu-wan Wei Yan-Li Liu Ophthalmic Center/Department of Ophthalmology Second Hospital Shandong University Jinan 250033 China Department of Anatomy School of Medicine Shandong University Jinan 250012 China

Objective To investigate the effect of emodin on lipopolysaccharides （LPS）-induced corneal injury in rats. Methods Three parallel incisions on the central surface of corneal epithelium were made and LPS was applied on them to induce corneal injury in Wistar rats. All rats were randomly divided into emodin group （n=40） and keratitis group （n=40）. Rats in the emodin group received subconjunctival injection of emodin and rats in the keratitis group received its vehicle 30 minutes before LPS exposure. At different time points-1 3, 6, 12, and 24 hours after LPS exposure, the symptoms of all rats were observed and the severity of their ocular inflammation was examined with a slit lamp microscope, then 8 rats in each group were killed through cervical dislocation and their eyes were enucleated and prepared to observe pathological changes of corneal tissue under a light microscope. The activation of nuclear factor-loB （NF-κB） under different condi- tions was determined by Western blot. Immunocytochemistry staining with an antibody against intercellular adhesion molecule-1 （ICAM-1） was performed to identify positive cells in corneal tissues. Results The model of acute keratitis was successfully established in Wistar rats. LPS could induce a typical corneal inflammatory response, such as hyperemia, corneal edema and opacity, which were observed in model rats. Compared with keratitis group, both ocular behaviors and damages of the corneal structure were improved in emodin group. Furthermore, the activation of NF-κB and the expression of ICAM-1 induced by LPS were markedly inhibited in emodin group. Conclusion Emodin can inhibit the activation of NF-κB and the expression of ICAM-I induced by LPS in corneas, protect against acute corneal injury, and improve symptoms in rats.

关键词： corneal, injury emodin lipopolysaccharides nuclear factor-κB

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初始可切除型胃癌肝转移不同治疗方式预后情况及其影响因素分析的全国多中心临床研究

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中华消化外科杂志 2024年第1期23卷 114-124页

作者：李力高云鹤商亮唐兆庆薛侃余江梁延锐何子锐柯彬郑华龙黄华熊建平何中原李佶阳卢婷婷宋奇赢刘诗贺郗洪庆唐云乔治梁寒季加孚陈凛解放军医学院研究生院北京100853 解放军总医院第一医学中心普通外科医学部北京100853 山东第一医科大学附属省立医院胃肠外科济南250021 复旦大学附属中山医院普通外科上海200032 南方医科大学南方医院普通外科广州510515 北京大学肿瘤医院胃肠外科北京100142 上海交通大学医学院附属瑞金医院普通外科上海200025 天津医科大学肿瘤医院胃部肿瘤科天津300060 福建医科大学附属协和医院胃外科福州350001 复旦大学附属肿瘤医院胃外科上海200032 中国医学科学院肿瘤医院胰胃外科北京100021 南京医科大学第一附属医院普通外科南京210029

目的探讨初始可切除型胃癌肝转移(GCLM)不同治疗方式的预后情况,分析预后的影响因素。方法采用回顾性队列研究方法。收集2010年1月至2019年12月基于真实世界数据的GCLM诊疗全国多中心回顾性队列研究数据库中327例初始可切除型GCLM患者... 详细信息

目的探讨初始可切除型胃癌肝转移(GCLM)不同治疗方式的预后情况,分析预后的影响因素。方法采用回顾性队列研究方法。收集2010年1月至2019年12月基于真实世界数据的GCLM诊疗全国多中心回顾性队列研究数据库中327例初始可切除型GCLM患者的临床病理资料;男267例,女60例;年龄为61(54,68)岁。根据患者具体情况分别行根治性手术联合系统治疗、姑息性手术联合系统治疗、单纯系统治疗。观察指标:(1)不同治疗方式患者临床特征情况。(2)不同治疗方式患者预后情况。(3)初始可切除型GCLM患者预后的影响因素分析。(4)根治性手术联合系统治疗和姑息性手术联合系统治疗潜在获益人群筛选。正态分布的计量资料以x±s表示,组间比较采用独立样本t检验。偏态分布的计量资料以M(Q1,Q3)表示,组间比较采用秩和检验。计数资料以绝对数或百分比表示,组间比较采用χ2检验。采用Kaplan-Meier法计算生存率并绘制生存曲线,Log-Rank检验进行生存分析。采用COX风险比例回归模型进行单因素和多因素分析。倾向评分匹配按1∶1最近邻匹配法匹配,卡钳值为0.1。采用森林图筛选不同手术联合系统治疗的潜在获益人群。结果 (1)不同治疗方式患者临床特征情况。327例患者中,行根治性手术联合系统治疗118例,行姑息性手术联合系统治疗164例,行单纯系统治疗45例;3者吸烟、饮酒、胃原发肿瘤部位和肿瘤最大径、肝转移肿瘤部位、转移时限比较,差异均有统计学意义(P<0.05)。(2)不同治疗方式患者预后情况。327例患者的中位总生存时间为19.9个月(95%可信区间为14.9~24.9个月),1、3年总生存率分别为61.3%、32.7%。行根治性手术联合系统治疗、姑息性手术联合系统治疗、单纯系统治疗患者的1年总生存率分别为68.3%、63.1%、30.6%,3年总生存率分别为41.1%、29.9%、11.9%,3者总生存率比较,差异有统计学意义(χ2=19.46,P<0.05)。进一步分析,行根治性手术联合系统治疗和单纯系统治疗患者总生存率比较,差异有统计学意义(风险比=0.40,95%可信区间为0.26~0.61,P<0.05);行姑息性手术联合系统治疗和单纯系统治疗患者总生存率比较,差异有统计学意义(风险比=0.47,95%可信区间为0.32~0.71,P<0.05)。(3)初始可切除型GCLM患者预后的影响因素分析。多因素分析结果显示:胃原发肿瘤越大、肿瘤分化程度为低分化、肝转移肿瘤越大、肝转移肿瘤数目为多发是影响初始可切除型GCLM患者预后的独立危险因素(风险比=1.20,1.70,1.20,2.06,95%可信区间为1.14~1.27,1.25~2.31,1.04~1.42,1.45~2.92,P<0.05);免疫或靶向治疗、根治性手术联合系统治疗、姑息性手术联合系统治疗是影响初始可切除型GCLM患者预后的独立保护因素(风险比=0.60,0.39,0.46,95%可信区间为0.42~0.87,0.25~0.60,0.30~0.70,P<0.05)。(4)根治性手术联合系统治疗和姑息性手术联合系统治疗潜在获益人群筛选。森林图分析结果显示:肿瘤分化程度为高-中分化、肝转移肿瘤部位为左半肝患者行根治性手术联合系统治疗总生存率均优于行姑息性手术联合系统治疗(风险比=0.21,0.42,95%可信区间为0.09~0.48,0.23~0.78,P<0.05)。结论与行单纯系统治疗比较,行根治性手术联合系统治疗或姑息性手术联合系统治疗可以改善初始可切除型GCLM患者预后。胃原发肿瘤越大、肿瘤分化程度为低分化、肝转移肿瘤越大、肝转移肿瘤数目为多发是影响初始可切除型GCLM患者预后的独立危险因素;免疫或靶向治疗、根治性手术联合系统治疗、姑息性手术联合系统治疗是影响初始可切除型GCLM患者预后的独立保护因素。

关键词：胃肿瘤肝转移手术治疗系统治疗预后影响因素

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Eight novel mutations in the ABCD1 gene and clinical characteristics of 25 Chinese patients with X-linked adrenoleukodystrophy

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World Journal of Pediatrics 2015年第4期11卷 366-373页

作者： Shan-Shan Chu Jun Ye Hui-Wen Zhang Lian-Shu Han Wen-Juan Qiu Xiao-Lan gao xue-Fan Gu Department of Pediatric Endocrinology and Genetic Metabolism Shanghai Institute for Pediatric ResearchXinhua HospitalShanghai Jiao Tong University School of MedicineShanghaiChina

Background:X-linked adrenoleukodystrophy(X-ALD)is a fatal neurodegenerative disease caused by mutations in the adenosine triphosphate-binding cassette D1(ABCD1)*** study aimed to retrospectively investigate the clinical characteristics of 25 patients with X-ALD including members of large pedigrees,to analyze ABCD1 gene mutations,the effect of gene novel variants on ALD protein(ALDP)structure and function,and to expand gene mutation spectrum of Chinese ***:Twenty-five male patients diagnosed with X-ALD were enrolled in this *** clinical characteristics of the patients were retrospectively summarized by reviewing medical records or telephone ***1 gene mutations were *** pathogenicity of novel missense variants was analyzed using cobalt constraint-based multiple protein alignment tool,polymorphism phenotyping,sorting intolerant from tolerant,Align-Grantham variation and Grantham deviation,and Swiss-Program Database Viewer 4.04 software,***:Childhood cerebral form ALD(CCALD)is the most common phenotype(64%)in the 25 patients with *** progressive deterioration of neurological and cognitive functions is the main clinical *** demyelination of the brain white matter and elevated plasma very long chain fatty acids(VLCFAs)were found in all *** phenotypes were also presented within family members of the ***-two different mutations including 8 novel mutations in the ABCD1 gene were identifi ed in the 25 *** the mutations,63.6%were missense mutations and 34.8%located in exon *** amino acid residues of three novel missense mutations in eight species were highly conserved,and were predicted to be"probably"damaging to ALDP *** other five novel mutations were splice,nonsense,deletion or duplication ***:CCALD is the most common phenotype(64%)in our patients with *** novel mutations in the ABCD1 gene identifi ed are disease-causing muta

关键词： ABCD1 protein adrenoleukodystrophy adrenoleukodystrophy protein missense variant mutation

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人类红系分化相关基因对慢性炎症诱导的造血干细胞损伤的保护作用

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军事医学 2024年第8期48卷 594-600页

作者：李思雨赵珂武云强吕志春孙慧颖赵雄伟薛阳高慧英向慎思李长燕安徽医科大学基础医学院军事科学院军事医学研究院河北大学

目的探究红系分化相关基因（EDAG）在慢性炎症感染下对造血干/祖细胞（HSPC）的影响。方法将8周龄EDAG-/-小鼠与野生型小鼠分为实验组和对照组，腹腔多次注射单核细胞增生李斯特菌（LM）构建感染性慢性炎症模型，腹腔多次注射低剂量... 详细信息

目的探究红系分化相关基因（EDAG）在慢性炎症感染下对造血干/祖细胞（HSPC）的影响。方法将8周龄EDAG-/-小鼠与野生型小鼠分为实验组和对照组，腹腔多次注射单核细胞增生李斯特菌（LM）构建感染性慢性炎症模型，腹腔多次注射低剂量聚胞苷酸[Poly（I∶C）]构建无菌性慢性炎症模型，检测在2种慢性炎症刺激下，EDAG敲除对小鼠造血系统的影响。结果在LM反复感染模型下，EDAG-/-小鼠出现造血干/祖细胞以及长期造血干细胞（LT-HSC）减少，且外周血出现明显的髓系分化偏向。与此相似，EDAG-/-也可导致无菌性慢性炎症模型中HSPC数量减少，体外集落形成能力下降。结论在慢性炎症刺激下，EDAG缺失加速年轻小鼠HSPC的耗竭，提示EDAG对慢性炎症诱导的造血干祖细胞损伤具有重要保护作用。

关键词：红系分化相关基因慢性炎症造血干/祖细胞耗竭衰老

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Bilateral and symmetric C1-C2 dumbbell ganglioneuromas associated with neurofibromatosis type 1: A case report

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World Journal of Clinical Cases 2019年第1期7卷 109-115页

作者： Chun-Yu Tan Jia-Wei Liu Yi Lin Xin-Xin Tie Peng Cheng xue Qi Yue gao Zong-Ze Guo Department of Neurosurgery The First Hospital of China Medical University X-ray Department The First Hospital of China Medical University Department of Pathology The First Hospital of China Medical University

BACKGROUND Ganglioneuroma(GN) is a rare and benign tumor that originates from autonomic nervous system ganglion cells. The most frequently involved sites are the posterior mediastinum, the abdominal cavity, and the retroperitoneal space. It rarely occurs in the cervical area, compressing the spinal cord. Neurofibromatosis type 1(NF-1) is an autosomal dominant inheritance disorder, whose prevalence rate approximates one per *** SUMMARY We report an extremely rare case of bilateral and symmetric dumbbell GNs of the cervical spine with NF-1. A 27-year-old man with NF-1 presented with a one-year history of gradually progressive right upper extremity weakness and numbness in both hands. Magnetic resonance imaging showed bilateral and symmetric dumbbell lesions at the C1-C2 levels compressing the spinal cord. We performed total resection of bilateral tumors, and the postoperative histopathological diagnosis of the resected mass was GN. After operation, the preoperative symptoms were gradually relieved without complications. To our knowledge,this is the sixth report of cervical bilateral dumbbell *** In some cases, cervical bilateral dumbbell GNs could be associated with *** exact diagnosis cannot be obtained before operation, and pathological outcome is the current gold standard. Surgical resection is the most effective option, and disease outcome is generally good after treatment.

关键词： Ganglioneuroma Cervical Bilateral Dumbbell Surgery Case report

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Synthesis of atomically thin GaSe wrinkles for strain sensors

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Frontiers of physics 2016年第2期11卷 103-107页

作者： Cong Wang Sheng-xue Yang Hao-Ran Zhang Le-Na Du Lei Wang Feng-You Yang Xin-zheng Zhang Qian Liu The MOE Key Laboratory of Weak-Light Nonlinear Photonics TEDA Applied Physics Institute and School of Physics Nankai University Tianjin 300457 China National Center for Nanoscience and Technology No. 11 Beiyitiao Zhongguancun Beijing 100190 China School of Materials Science and Engineering Beihang University Beijing 100191 PR China

A wrinkle-based thin-film device can be used to develop optoelectronic devices, photovoltaics, and strain sensors. Here, we propose a stable and ultrasensitive strain sensor based on two-dimensional （2D） semiconducting gallium selenide （GaSe） for the first time. The response of the electrical re- sistance to strain was demonstrated to be very sensitive for the GaSe-based strain sensor, and it reached a gauge factor of -4.3, which is better than that of graphene-based strain sensors. The results show us that strain engineering on a nanoscale can be used not only in strain sensors but also for a wide range of applications, such as flexible field-effect transistors, stretchable electrodes, and flexible solar cells.

关键词： GaSe wrinkles strain sensor

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