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A SQUID Bootstrap Circuit with a Large Parameter Tolerance

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Chinese Physics Letters 2013年第1期30卷 219-222页

作者： ZHANG Guo-Feng ZHANG Yi Hans-Joachim Krause KONG xiang-yan Andreas Offenhäusser XIE Xiao-Ming State Key Laboratory of Functional Materials for Informatics Shanghai Institute of Microsystem and Information TechnologyChinese Academy of Sciences(CAS)Shanghai 200050 Peter Grünberg Institute(PGI-8) Forschungszentrum Jülich(FZJ)D-52425JülichGermany Joint Research Laboratory on Superconductivity and Bioelectronics Collaboration between CAS-Shanghai&FZJShanghai 200050

The voltage biased(SQUID)bootstrap circuit(SBC)was recently introduced as an effective means to reduce the preamplifier noise *** analyze the tolerances of the SBC noise suppression performance to spreads in SQUID and SBC circuit *** is found that the tolerance to spread mainly caused by the integrated circuit fabrication process could be extended by a one-time adjustable current feedback.A helium-cooled niobium SQUID with a loop inductance of 350 pH is employed to experimentally verify the *** this work,design criteria for fully integrated SBC devices with a high yield can be derived.

关键词： SQUID Bootstrap spread

Intrinsic viscosity of polymer solutions: fresh ideas to an old problem

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Science China Chemistry 2015年第5期58卷 835-838页

作者： Deyue yan State Key Laboratory of Metal Matrix Composites School of Chemistry and Chemical Engineering Shanghai Jiao Tong University

Intrinsic viscosity is one of the most fundamental properties of dilute polymer solutions; its study forms an integral part of the cornerstone of the modern macromolecular theory. However, a general theory applicable to any chain architectures and solvent conditions has remained elusive, due to the formidable challenges in the theoretical treatment of the long-range, many-body and accumulative hydrodynamic effects. Recently, Lijia An and coworkers at the Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, has developed a new approach that largely overcomes these challenges. Their new theory provides a simple and unified theoretical framework for describing the intrinsic viscosity of polymers with arbitrary architectures under any solvent conditions and forms the theoretical basis for inferring the polymer chain structure from intrinsic viscosity measurements. Comparisons with existing experimental data yield extensive, quantitative agreement.

关键词： polymer solution intrinsic viscosity polymer chain structure hyperbranched polymers hydrodynamic effects

A variational solution of 2-D sound-structure interaction problems

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Acta Mechanica Sinica 2006年第2期22卷 127-131页

作者： Yuying Huang Haidong Su Yu xiang Dept of MechanicsHuazhong University of Science & Technologyuhan 430074 China Dept. of Automotive Engineering Guangxi University of Technologyuzhou 545006 China

Based on the fluid-structure coupling theory, a localized variational principle for analyzing the sound radiation from elastic structure submerged in water due to harmonic excitations is presented. It will be a powerful tool to formulate various numerical methods for steady response of structural-acoustic systems. By means of this variational principle a hybrid element method, in which an analytical solution valid in most of the surrounding water is incorporated with finite elements distributed in the structure and its neighboring water, is devised. Computational examples are then given to demonstrate its high accuracy and time saving.

关键词： Variational principle Acoustic radiation Fluid-structure coupling vibration Hybrid element method

Bortezomib inhibits growth and sensitizes glioma to temozolomide(TMZ)via down-regulating the FOXM1-Survivin axis

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Cancer Communications 2019年第1期39卷 696-711页

作者： Jun-Hai Tang Lin yang Ju-xiang Chen Qing-Rui Li Li-Rong Zhu Qing-Fu Xu Guo-Hao Huang Zuo-Xin Zhang yan xiang Lei Du Zheng Zhou Sheng-Qing Lv Department of Neurosurgery Xinqiao HospitalThird Military Medical UniversityChongqing 400037P.R.China Department of Neurosurgery Changzheng Hospital and Shanghai Institute of NeurosurgerySecond Military Medical UniversityShanghai 200003P.R.China Institute of Pathology and Southwest Cancer Center Southwest HospitalThird Military Medical UniversityChongqing 400038P.R.China Department of Ultrasound Children HospitalChongqing Medical UniversityChongqing 400010P.R.China Department of Neurosurgery The Second Xiangya HospitalCentral South UniversityChangsha 410008HunanP.R.China

Background:High-grade glioma(HGG)is a fatal human ***,a proteasome inhibitor,has been approved for the treatment of multiple myeloma but its use in glioma awaits further *** study aimed to explore the chemotherapeutic effect and the underlying mechanism of bortezomib on ***:U251 and U87 cell viability and proliferation were detected by 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide(MTT)assay,tumor cell spheroid growth,and colony formation *** apoptosis and cell cycle were detected by flow ***(TMZ)-insensitive cell lines were induced by long-term TMZ treatment,and cells with stem cell characteristics were enriched with stem cell culture *** mRNA levels of interested genes were measured via reverse transcription-quantitative polymerase chain reaction,and protein levels were determined via Western blotting/immunofluorescent staining in cell lines and immunohistochemical staining in paraffin-embedded *** inoculating U87 cells subcutaneously,glioma xenograft models in nude mice were established for drug *** survival data were analyzed using the Kaplan-Meier ***:Bortezomib inhibited the viability and proliferation of U251 and U87 cells in a dose-and time-dependent manner by inducing apoptosis and cell cycle *** also significantly inhibited the spheroid growth,colony formation,and stem-like cell proliferation of U251 and U87 *** administrated in combination,bortezomib showed synergistic effect with TMZ in vitro and sensitized glioma to TMZ treatment both in vitro and in *** reduced both the mRNA and protein levels of Forkhead Box M1(FOXM1)and its target gene *** FOXM1-Survivin axis was markedly up-regulated in established TMZ-insensitive glioma cell lines and HGG *** levels of FOXM1 and Survivin were positively correlated with each other and both related to poor progno-sis in glioma patien

关键词： Glioma Bortezomib FOXM1 Survivin Temozolomide(TMZ) Chemotherapy

Protecting-group-free amination of halogenated nitrobenzaldehyde with palladium catalyst

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Chinese Chemical Letters 2010年第8期21卷 935-938页

作者： Jing Cao Jun xiang Feng Yong xiang Wu Ya Ya Tuo Key Laboratory of Environmentally Friendly Chemistry and Application of Ministry of Education College of ChemistryXiangtan UniversityXiangtan 411105China

"One-step"method for the synthesis of secondary aliphatic amine substituted nitrobenzaldehyde was *** the presence of Pd catalyst,halogenated nitrobenzaldehyde could be smoothly coupled with secondary aliphatic amine ... 详细信息

关键词： Halogenated nitrobenzaldehyde Secondary aliphatic amines Pd catalyst

Novel cellular therapies for hepatobiliary malignancies

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Hepatobiliary & Pancreatic Diseases International 2022年第5期21卷 450-454页

作者： Jing-Nan xue yan-Yu Wang Yun-Chao Wang Nan Zhang Long-Hao Zhang Zheng-Hui Lu Li-Jin Zhao Hai-Tao Zhao Department of Liver Surgery Peking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China Department of Hepatobiliary and Pancreatic Surgery Affiliated Hospital of Zunyi Medical UniversityZunyi 563000China Hepatobiliary and Pancreatic Surgery Shenzhen Qianhai Shekou Free Trade Zone HospitalShenzhen 518000China

Background:The mortalities of hepatobiliary malignancies are *** the failure of conventional chemotherapy and unsatisfactory outcome of molecular targeted drugs,immune-based therapy has become a new focus of research in hepatobiliary cancers *** sources:We performed a Pub Med search with relevant articles published up to May 2022 and the following keywords:cellular immunotherapy,hepatobiliary cancer,antigen receptor T cell therapy,and receptor-engineered T *** of clinical trials was obtained from https://***/.Results:Cell therapies for hepatobiliary malignancies are at early stage of *** current review showed that cellular therapies are safe and feasible in *** findings provide an important platform for future lager scale clinical trials on immunotherapy in patients with hepatobiliary ***:With the continuous advances of cellular immunotherapy,the combination of cellular immunotherapy with surgery,chemotherapy and radiotherapy will be new therapeutic strategies for patients with hepatobiliary cancer.

关键词： Cellular therapy Chimeric antigen receptor T cell therapy Receptor-engineered T cell Hepatobiliary malignancy

Propagation of Shear Waves Generated by Acoustic Radiation Force in Nondissipative Inhomogeneous Media

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Chinese Physics Letters 2012年第1期29卷 164-167页

作者： LU Ming-Zhu LIU xue-Jin SHI Yu KANG yan-Ni GUAN Yu-Bo WAN Ming-Xi The Key Laboratory of Biomedical Information Engineering of Ministry of Education Department of Biomedical EngineeringSchool of Life Science and TechnologyXi’an Jiaotong UniversityXi’an 710049

We concentrate on the nondissipative mechanism induced shear wave in inhomogenous *** shear wave equation of radiation force in inhomogeneous media is solved numerically with a finite-difference time-domain method.A rarely studied nondissipative mechanism of shear displacement due to a smooth medium inhomogeneity is *** is noted that unlike the dissipative effect,the nondissipative action on a localized inhomogeneity with its hardness parameter changing smoothly along the beam axis,compresses or stretches the focus *** shear waves in nondissipative inhomogeneous media remain the property of sharp turn with 100% peak positive displacement and 64% peak negative *** action is useful in discerning the water-like lesion.

关键词： method. dissipative inhomogeneous

Quantum Random Number Generation Based on Quantum Phase Noise

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Chinese Physics Letters 2013年第11期30卷 109-112页

作者： TANG Guang-Zhao JIANG Mu-Sheng SUN Shi-Hai MA xiang-Chun LI Chun-yan LIANG Lin-Mei Department of Physics National University of Defense TechnologyChangsha 410073 State Key Laboratory of High Performance Computing National University of Defense TechnologyChangsha 410073

We experimentally demonstrate a kind of high-quantum correlated,practical quantum random generation based on the quantum phase noise of a laser,which uniformly distributes in the range of(-π,π]by driving the laser with a stream of narrow electrical *** propose a working mode to further suppress the impact of phase drift after we use the passive measures(thermal and mechanical isolation)to slow it ***,a new method which ensures random numbers to be true representations of quantum characteristics is presented to quantify the quantum *** scheme has an inherent advantage for multiplex generation.

关键词： quantum uniformly narrow

Effects of Ce^(3+) doping on the structure and magnetic properties of Mn-Zn ferrite fibers

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Rare Metals 2009年第2期28卷 151-155页

作者： xiang, Jun Shen, xiangqian Zhu, Yongwei School of Materials Science and Engineering Jiangsu University Zhenjiang 212013 China School of Mechanical and Electrical Engineering Nanjing University of Aeronautics and Astronautics Nanjing 210016 China

Ce3+-doped Mn-Zn ferrite fibers were successfully prepared by the organic gel-thermal decomposition method from metal salts and citric acid. The composition,structure,and magnetic properties of these ferrite fibers were characterized by X-ray diffraction (XRD),scanning electron microscopy (SEM),and vibrating sample magnetometer (VSM). The results show that Mn0.2Zn0.8Fe2-xCexO4 (x = 0-0.04) fibers are featured with an average grain size of 11.6-12.7 nm,with diameters ranging between 1.0 to 3.5 μm and a high ...

关键词： ceramic fibers Mn-Zn ferrite thermal decomposition magnetic properties Ce3+-doped