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Contrast in vulnerability to freezing-induced xylem embolism contributes to divergence in spring phenology between diffuse-and ring-porous temperate trees

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Forest Ecosystems 2022年第6期9卷 734-744页

作者： Ai-Ying Wang Han-Xiao Cui xue-wei gong Jing-Jing Guo Nan Wu Guang-You Hao School of Life Sciences and Engineering Shenyang UniversityShenyang110044LiaoningChina Liaoning Key Laboratory of Urban Integrated Pest Management and Ecological Security College of Life Science and BioengineeringShenyang UniversityShenyang110044LiaoningChina CAS Key Laboratory of Forest Ecology and Management Institute of Applied EcologyChinese Academy of SciencesShenyang110016China University of Chinese Academy of Sciences Beijing100049China Tree Laboratory Shenyang Academy of Landscape-gardeningShenyang110016LiaoningChina

Background:The spring phenology and growth strategy of temperate tree species can be strongly linked to their sensitivity to frosts,which deserve more profound investigations under the background of climate warming particularly considering the advancement of spring phenology as well as the increase in frequency and intensity of spring cold ***:Spring phenologies,stem radial growth characteristics,frost sensitivity of leaves and stem hydraulic systems were studied in five diffuse-porous and five ring-porous temperate tree species under a common garden ***:The results showed that the spring leaf phenology of the diffuse-porous species was one to two weeks earlier than that of the ring-porous *** ring-porous species had significantly higher stem hydraulic conductivity than the diffuse-porous species(1.81 and 0.95 kg·m^(-1)·s^(-1)·MPa^(-1),P<0.05)but were more vulnerable to freeze-thaw induced xylem embolism than the *** a simulated freeze-thaw event,the average percentage loss of hydraulic conductivity in the current year shoots increased from 26.0%(native embolism)to 86.7%in the ring-porous species,while it only increased from 21.3%to 38.3%in the diffuse-porous *** spring phenology was clearly correlated with vulnerability to freeze-thaw induced embolism,with the more vulnerable ring-porous species exhibited substantially delayed phenology to reduce risks of catastrophic hydraulic dysfunction during spring ***,ring-porous species can offset the postponed onset of growth and gained even higher annual growth due to significantly higher hydraulic efficiency and leaf gas exchange ***:Contrasts between ring-porous and diffuse-porous species in resistance to freeze-thaw induced embolism suggest that they face different selective pressures from early spring frosts,which may at least be partially responsible for their divergence in spring phenology and growth strategy and can potentially lead to di

关键词： Diffuse-porous trees Freeze-thaw cycle Frost damage Ring-porous trees Spring phenology Xylem embolism

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Change of hs-CRP,sVCAM-1,NT-proBNP levels in patients with pregnancy-induced hypertension after therapy with magnesium sulfate and nifudipine

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Asian Pacific Journal of Tropical Medicine 2013年第11期6卷 897-901页

作者： Li Wang Zhi-Qiang Liu Ying-Qian Huo Li-Juan Yao xue-gong wei Yun-Fang Wang Affiliated Hospital of Binzhou Medical College

Objective:To investigate the change of the hs-CRP,sVC AM-1,NT-proBNP levels of the patients with pregnancy-induced hypertension(PIH) ***:A total of 200 patients with PIH were divided into mild,moderate and severe group,and 50 healthy pregnancy patients served as the control *** serum sVCAM-1 levels were detected by enzyme-linked immunosorbent assay,hs-CRP were detected by immunity transmission turbidity,and NT-proBNP levels were determined by the colloidal gold *** were treated with magnesium sulfate and nifudipine and the contrastive analysis was performed before and after *** the pathological changes in placental of PIH patients were delected by hematoxylin-eosin staining at the same ***:The hs-CRP,sVCAM-l,NT-proBNP levels of patients in the mild, moderate and severe PHI group were significantly higher than that in the control group(P<0.05). The hs-CKP,sVCAM-l,NT-proBNP levels in the severe group were significantly higher than the mild group and the moderate group,the difference was statistically significant(P<0.05).The hsCRP,sVCAM-l,NT-proBNP of the moderate group were significantly higher than the mild group(P<0.05).There was a positive correlation between hs-CRP,sVCAM-1,NT-proBNP expression levels and the degree of the *** expression of hs-CRP,sVCAM-1,NT-proBNP levels of the moderate and the severe group were significantly decreased(P<0.05).The number of placental villi and interstitial blood vessel in the moderate and severe PIH group were significantly less than the control group(P<0.05).Conclusions:The increased levels of serum hs-CRP,sVCAM-1, NT-proBNP may be involved in the process of vascular endothelial cell injury of the PIH,and the hs-CRP,sVCAM-1,NT-proBNP can be used as the auxiliary index for diagnosis of PIH and determination of PIH severity.

关键词： Pregnancy-induced hypertension Soluble vascular cell adhesion molecule-1 Ultra-sensitivity C-reactive protein Amino-terminal pro-brain natriuretic peptide

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Anti-HBV effect of TAT-HBV targeted ribonuclease

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World Journal of Gastroenterology 2003年第7期9卷 1525-1528页

作者： Jin Ding Jun Liu Cai-Fang xue wei-Dong gong Ying-Hui Li Ya Zhao Department of Etiology,Fourth Military Medical University,Xi’an 710032,Shaanxi Province,China Department of Etiology Fourth Military Medical University Xi'an 710032 Shaanxi Province China.

AIM: To prepare and purify TAT-HBV targeted ribonuclease fusion protein, evaluate its transduction activity and investigate its effect on HBV replication in 2.2.15 ***: The prokaryotic expression vector pTAT containing TR gene was used in transforming E. coli BL21(DE3) LysS and TR was expressed with the induction of IPTG. The TAT-TR fusion protein was purified using Ni-NTA-agrose and PD-10 desalting columns, and analyzed by SDSPAGE. Transduction efficiency of TAT-TR was detected with immunofluorescence assay and the concentration of HBeAg in the supernatant of the 2.2.15 cells was determined via solid-phase radioimmunoassay (spRIA). MTT assay was used to detect the cytotoxicity of ***: The SDS-PAGE showed that the TAT-TR fusion protein was purified successfully, and the purity of TAT-TR was 90 %. The visualization of TAT-TR by immunofiuorescence assay indicated its high efficiency in transducing 2.2.15 *** result suggests that TAT-TR could inhibit the replication of HBV effectively, it didn′t affect cell growth and had no ***: TAT-TR possesses a significant anti-HBV activity and the preparation of TAT-TR fusion protein has laid the foundation for the use of TR in the therapeutic trial of HBV infection.

关键词：乙型肝炎病毒核糖核酸酶 TAT融合蛋白蛋白纯化

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产前盆底肌功能锻炼对阴道分娩及盆底肌张力的影响

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中国基层医药 2010年第23期17卷 3196-3197页

作者：魏学功滨州医学院附属医院妇产科山东省滨州256603

目的观察产前盆底肌功能锻炼对阴道分娩及盆底肌张力的影响. 方法回顾性分析阴道分娩的90例产妇临床资料,随机分为两组各45例.对照组采用常规产前准备,观察组在常规产前准备的基础上进行产前盆底肌功能锻炼.比较两组产妇的产程、分娩... 详细信息

目的观察产前盆底肌功能锻炼对阴道分娩及盆底肌张力的影响. 方法回顾性分析阴道分娩的90例产妇临床资料,随机分为两组各45例.对照组采用常规产前准备,观察组在常规产前准备的基础上进行产前盆底肌功能锻炼.比较两组产妇的产程、分娩方式及盆底肌张力. 结果观察组产程明显短于对照组,观察组顺产率为93.3%、明显高于对照组的77.8%;观察组产妇分娩后的盆底肌张力明显优于对照组,组间差异均有统计学意义（P＜0.05）. 结论产前盆底肌功能锻炼有助于胎儿顺产和产妇产后康复.

关键词：阴道骨盆底,肌肉松弛

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小剂量肝素与舒喘灵配伍治疗妊娠合并子宫肌瘤红色变性的临床研究

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中国妇幼保健 2011年第28期26卷 4451-4453页

作者：魏学功刘艳妮李丽滨州医学院附属医院妇产科山东滨州256600

目的:探讨应用小剂量肝素配伍舒喘灵治疗妊娠期子宫肌瘤红色变性的临床价值。方法:选择2002年5月～2008年1月该院产科19例妊娠合并子宫肌瘤红色变性患者,给予小剂量肝素配伍舒喘灵治疗,并对此19例患者进行随访的数据资料进行分析,同以... 详细信息

目的:探讨应用小剂量肝素配伍舒喘灵治疗妊娠期子宫肌瘤红色变性的临床价值。方法:选择2002年5月～2008年1月该院产科19例妊娠合并子宫肌瘤红色变性患者,给予小剂量肝素配伍舒喘灵治疗,并对此19例患者进行随访的数据资料进行分析,同以往临床治疗方法相比较。结果:19例中有12例维持妊娠至足月行剖宫产术并肌瘤挖除术,4例足月妊娠发动宫缩后经阴分娩,3例于接近足月时发动宫缩,剖宫产2例,经阴分娩1例,新生儿均健康存活(100%)。结论:与以往妊娠合并子宫肌瘤红色变性先兆早产(流产)抑制宫缩保胎治疗相比较,小剂量肝素配伍舒喘灵治疗妊娠期子宫肌瘤红色变性,效果明显,仅需3～7天即可从根本上控制先兆早产(流产),使健康存活儿出生率明显增高,达到100%健康存活率。同时没有应用硫酸镁,减少了孕妇因长时间输液导致的不适感,值得临床推广应用。

关键词：子宫肌瘤妊娠红色变性小剂量肝素舒喘灵

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Correlation analyse between thyroid hormone levels and severity of schizophrenia symptoms

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World Journal of Psychiatry 2025年第1期15卷 63-71页

作者： Qi-Hui Jiang wei-Dong gong Department of Endocrinology and Metabolism Hengyang Central HospitalHengyang 421000Hunan ProvinceChina Breast Tumor Surgical Outpatient Hengyang Central HospitalHengyang 421000Hunan ProvinceChina

BACKGROUND The imbalance of hormone levels in the body is closely related to the occurrence and progression of schizophrenia,especially thyroid *** To study the relationship between triiodothyronine(T3),thyroxine(T4),free T3(FT3),free T4(FT4),thyroid stimulating hormone(TSH)and *** In this study,100 schizophrenia patients were selected from our hospital between April 2022 and April *** clinical data were analyzed *** on the Positive and Negative Syndrome Scale(PANSS)score,patients were divided into mild(1-3 points,n=39),moderate(4 points,n=45),and severe groups(5-7 points,n=16).Additionally,55 healthy individuals served as a control *** blood samples were collected to measure T3,T4,FT3,FT4,TSH,and cortisol concentrations,analyzing their relationship with PANSS *** The serum levels of T3,FT3,FT4,TSH and cortisol in the schizophrenia group were lower than those in the control group(P<0.05).With the increase of the severity of the disease,the concentrations of T3 and T4 decreased,while the con-centrations of TSH and cortisol increased(P<0.05).The concentrations of TSH and cortisol were positively correlated with the PANSS score,while T3 and T4 were negatively correlated with the PANSS score(P<0.05).The receiver ope-rating characteristic curve results showed that T3,T4,TSH,and cortisol had good efficacy in the diagnosis of *** results showed that decreased T3 level,decreased T4 level,decreased TSH level and increased cortisol level may be independent risk factors for *** Thyroid hormone levels are associated with the severity of schizophrenia symptoms,which can provide new solutions for the diagnosis and treatment of schizophrenia.

关键词： Thyroid hormone Schizophrenia Symptom severity Positive and Negative Syndrome Scale score Cortisol

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基于光子晶体腔链的量子态传输及相位门的实现

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量子光学学报 2018年第1期24卷 30-38页

作者：范明营周凤雪林功伟钮月萍龚尚庆华东理工大学理学院

研究了光子晶体腔链中任意两奇数节点间量子态传输及相位门实现的问题。发现在绝热条件下,通过求解原子和光子晶体腔链耦合模型的暗态,可实现一维光子晶体耦合腔链中两个腔之间二维量子态的传输及可控相位门。在量子态传输的过程中若原... 详细信息

研究了光子晶体腔链中任意两奇数节点间量子态传输及相位门实现的问题。发现在绝热条件下,通过求解原子和光子晶体腔链耦合模型的暗态,可实现一维光子晶体耦合腔链中两个腔之间二维量子态的传输及可控相位门。在量子态传输的过程中若原子与腔的耦合强度足够大,腔的激发态的布居数小到可以被忽略。最后讨论了腔链的长度与相位门保真度的关系以及腔链的长度、初态的制备、腔的衰减、原子与腔的耦合强度对量子态传输保真度的影响。

关键词：光子晶体腔链量子态传输暗态相位门

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断脐时机的选择对阴道分娩早产儿的影响研究

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世界最新医学信息文摘 2019年第A期19卷 35-36页

作者：吴洪枝魏学功滨州医学院滨州市沾化区人民医院产二科滨州医学院附属医院

目的探讨选择不同断脐时机对经阴道分娩早产儿的影响。方法选取2016年1月至2018年12月在我院经阴道分娩的60例早产儿作为研究对象,随机分组,每组20例,对照组采用常规断脐,即娩出10秒内断脐;观察组A在新生儿娩出后1分钟断脐;观察组B新生... 详细信息

目的探讨选择不同断脐时机对经阴道分娩早产儿的影响。方法选取2016年1月至2018年12月在我院经阴道分娩的60例早产儿作为研究对象,随机分组,每组20例,对照组采用常规断脐,即娩出10秒内断脐;观察组A在新生儿娩出后1分钟断脐;观察组B新生儿娩出后待脐带停止搏动后断脐。比较3组早产儿的相关指标。结果 3组新生儿pH、二氧化碳分压（PCO;）、碱剩余（BE）组间比较无显著性差异（P> 0.05）;观察组B新生儿血氧分压（PO;）水平显著高于对照组和观察组A（P<0.05）;观察组A和观察组B新生儿血红蛋白（Hb）和红细胞压积（HCT）水平均显著高于对照组（P<0.05）,观察组B Hb和HCT水平均显著高于观察组A（P<0.05）。结论延缓断脐时间有助于早产新生儿血氧的供应,是一种有效改善早产新生儿健康状况的手段。

关键词：断脐时间晚断脐早产儿阴道分娩

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妊娠期糖尿病患者的代谢变化对胎儿的影响

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中国妇幼健康研究 2010年第4期21卷 430-431,564页

作者：梁葵香魏学功王佳滨州医学院附属医院山东滨州256603

目的研究妊娠期糖尿病患者的胎儿成长与母体内代谢特点的关系.方法回顾性地分析137名诊断为妊娠期糖尿病孕妇的资料,对其孕前身体质量指数、口服75g葡萄糖耐量试验、入院时糖化血红蛋白、甘油三酯、总胆固醇、高密度脂蛋白和低密度脂... 详细信息

目的研究妊娠期糖尿病患者的胎儿成长与母体内代谢特点的关系.方法回顾性地分析137名诊断为妊娠期糖尿病孕妇的资料,对其孕前身体质量指数、口服75g葡萄糖耐量试验、入院时糖化血红蛋白、甘油三酯、总胆固醇、高密度脂蛋白和低密度脂蛋白水平进行研究,并分析这些参数与新生儿出生体重和巨大儿发病率的关系.结果新生儿出生体重与产妇孕前身体质量指数、口服75g葡萄糖耐量试验空腹血糖及2小时血糖、糖化血红蛋白、甘油三酯呈正性相关关系（R分别为0.202、0.231、0.141、0.113、0.121,均P〈0.05）,差异有统计学意义.产妇孕前身体质量指数是预测巨大儿的最可靠因素.结论新生儿出生体重和巨大儿的发病率与妊娠期糖尿病患者的身体质量指数、血糖水平、糖化血红蛋白、甘油三酯的代谢参数有关,因此应控制这些参数,以降低患者围产期的风险性.

关键词：妊娠期糖尿病身体质量指数巨大儿代谢参数围产期

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Potassium and calcium channels in different nerve cells act as therapeutic targets in neurological disorders

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Neural Regeneration Research 2025年第5期20卷 1258-1276页

作者： Qing Qiu Mengting Yang Danfeng gong Haiying Liang Tingting Chen Department of Pharmacology School of PharmacyNantong UniversityNantongJiangsu ProvinceChina Jiangsu Province Key Laboratory of Inflammation and Molecular Drug Target NantongJiangsu ProvinceChina Department of Pharmacy Longyan First Affiliated Hospital of Fujian Medical UniversityLongyanFujian ProvinceChina

The central nervous system, information integration center of the body, is mainly composed of neurons and glial cells. The neuron is one of the most basic and important structural and functional units of the central nervous system, with sensory stimulation and excitation conduction functions. Astrocytes and microglia belong to the glial cell family, which is the main source of cytokines and represents the main defense system of the central nervous system. Nerve cells undergo neurotransmission or gliotransmission, which regulates neuronal activity via the ion channels, receptors, or transporters expressed on nerve cell membranes. Ion channels, composed of large transmembrane proteins, play crucial roles in maintaining nerve cell homeostasis. These channels are also important for control of the membrane potential and in the secretion of neurotransmitters. A variety of cellular functions and life activities, including functional regulation of the central nervous system, the generation and conduction of nerve excitation, the occurrence of receptor potential, heart pulsation, smooth muscle peristalsis, skeletal muscle contraction, and hormone secretion, are closely related to ion channels associated with passive transmembrane transport. Two types of ion channels in the central nervous system, potassium channels and calcium channels, are closely related to various neurological disorders, including Alzheimer's disease, Parkinson's disease, and epilepsy. Accordingly, various drugs that can affect these ion channels have been explored deeply to provide new directions for the treatment of these neurological disorders. In this review, we focus on the functions of potassium and calcium ion channels in different nerve cells and their involvement in neurological disorders such as Parkinson's disease, Alzheimer's disease, depression, epilepsy, autism, and rare disorders. We also describe several clinical drugs that target potassium or calcium channels in nerve cells and could be u

关键词： astrocytes calcium channels central nervous system extracellular ion concentration microglia neurological disorders neurons potassium channels

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