检索结果-南通市图书馆

Genetic Analysis of Distorted Segregation Ratio of Mating Types AmongBasidiospores in Lentinula edodes

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Agricultural Sciences in China 2008年第4期7卷 415-422页

作者： CHENG Shui-ming lin Fan-xue College of Life Science and Engineering Huanggang Normal University Huanggang 438000 P.R.China State Key Laboratory of Agricultural Microbiology Institute of Applied Mycology Huazhong Agricultural University Wuhan 430070 P. R. China

This study prepared 17 strains of Lentinula edodes, including wild and cultivated strains as materials, and statistically analyzed the ratios of spores from different aspects via mating types＇ analysis and the OWE-SOJ technique. The results from this study first systematically identified skewed expected distribution of mating-type factors segregation in Lentinula edodes spores has commonly statistical meanings in wild and cultivated strains. Genetic analysis of positive and negative parental-recombined fruiting showed that the nuclear type of F1 progeny spores among those strains segregated through theoretical distribution mainly depended on the combined state of parental dikaryons, and the predominant spores were those with the mating type identical to the dikaryotic parent, indicating that the genetic basis of segregation distortion of spores is different from that of protoplast monokaryons in which the B factor takes predominant responsibility for that phenomenon, and it cooperates A factor with B factor to influence the ratio of spores.

关键词： mating-type factor basidiospore Lentinula edodes segregation distortion

A low-power Rijndael S-Box based on pass transmission gate and composite field arithmetic

在线全文

学校读者我要写书评

暂无评论

Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2007年第10期8卷 1553-1559页

作者： ZENG Yong-hong ZOU xue-cheng LIU Zheng-lin LEI Jian-ming Research Center for VLSI and Systems Department of Electronic Science ＆ Technology Huazhong University of Science ＆ Technology Wuhan 430074 China

Using composite field arithmetic in Galois field can result in the compact Rijndael S-Box. However, the power con- sumption of this solution is too large to be used in resource-limited embedded systems. A full-custom hardware implementation of composite field S-Box is proposed for these targeted domains in this paper. The minimization of power consumption is implemented by optimizing the architecture of the composite field S-Box and using the pass transmission gate (PTG) to realize the logic functions of S-Box. Power simulations were performed using the netlist extracted from the layout. HSPICE simulation results indicated that the proposed S-Box achieves low power consumption of about 130 μW at 10 MHz using 0.25 μm/2.5 V technology, while the consumptions of the positive polarity reed-muller (PPRM) based S-Box and composite field S-Box based on the conventional CMOS logic style are about 240 μW and 420 μW, respectively. The simulations also showed that the presented S-Box obtains better low-voltage operating property, which is clearly relevant for applications like sensor nodes, smart cards and radio frequency identification (RFID) tags.

关键词： Composite field Rijndael S-Box Full-custom Pass transmission gate (PTG) Low power consumption Low-voltage

Pharmacological targeting cGAS/STING/NF-κB axis by tryptanthrin induces microglia polarization toward M2 phenotype and promotes functional recovery in a mouse model of spinal cord injury

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第11期20卷 3287-3301页

作者： Ziwei Fan Mengxian Jia Jian Zhou Zhoule Zhu Yumin Wu Xiaowu lin Yiming Qian Jiashu Lian Xin Hua Jianhong Dong Zheyu Fang Yuqing Liu Sibing Chen Xiumin xue Juanqing Yue Minyu Zhu Ying Wang Zhihui Huang Honglin Teng Department of Orthopedics(Spine Surgery) the First Affiliated Hospital of Wenzhou Medical UniversityWenzhouZhejiang ProvinceChina School of Pharmacy Hangzhou Normal UniversityHangzhouZhejiang ProvinceChina Department of Neurology The First Affiliated Hospital of Wenzhou Medical UniversityWenzhouZhejiang ProvinceChina Department of Pathology Affiliated Hangzhou First People’s HospitalSchool of MedicineWestlake UniversityHangzhouZhejiang ProvinceChina Department of Clinical Research Center Affiliated Hangzhou First People’s HospitalSchool of MedicineWestlake UniversityHangzhouZhejiang ProvinceChina

The M1/M2 phenotypic shift of microglia after spinal cord injury plays an important role in the regulation of neuroinflammation during the secondary injury phase of spinal cord *** of shifting microglia polarization from M1(neurotoxic and proinflammatory type)to M2(neuroprotective and anti-inflammatory type)after spinal cord injury appears to be *** possesses an anti-inflammatory biological ***,its roles and the underlying molecular mechanisms in spinal cord injury remain *** this study,we found that tryptanthrin inhibited microglia-derived inflammation by promoting polarization to the M2 phenotype in *** promoted M2 polarization through inactivating the cGAS/STING/NF-κB ***,we found that targeting the cGAS/STING/NF-κB pathway with tryptanthrin shifted microglia from the M1 to M2 phenotype after spinal cord injury,inhibited neuronal loss,and promoted tissue repair and functional recovery in a mouse model of spinal cord ***,using a conditional co-culture system,we found that microglia treated with tryptanthrin suppressed endoplasmic reticulum stress-related neuronal *** together,these results suggest that by targeting the cGAS/STING/NF-κB axis,tryptanthrin attenuates microglia-derived neuroinflammation and promotes functional recovery after spinal cord injury through shifting microglia polarization to the M2 phenotype.

关键词： cGAS/STING functional recovery microglia neuroinflammation neuroprotection nuclear factor-κB polarization spinal cord injury tryptanthrin

Risk assessment of mountain tourism on the Western Sichuan Plateau,China

在线全文

学校读者我要写书评

暂无评论

Journal of Mountain Science 2023年第11期20卷 3360-3375页

作者： ZHANG Yu-Qing WANG Yue-lin LI Hong LI xue-ming School of Geography Liaoning Normal UniversityDalian 116029China Centre for Marine Economy and Sustainable Development Research Liaoning Normal UniversityDalian 116029China

As an important site for tourism activities,mountainous areas may generate greater tourism risks than plain areas due to potential natural disasters,social issues,scenic area management,and tourist *** Sichuan Plateau is mostly mountainous area and tourism is its pillar industry,Therefore,the assessment of the tourism risks on the Western Sichuan Plateau is of academic value and practical *** this study,we use statistical and remote sensing data,fishbone diagram,and the entropy weighting method to construct a tourism risk evaluation model and classify risks into different levels,and we also use a geographic information system(GIS)for spatial mapping to quantify and spatialize the *** objectives are 1)to identify the risk sources in the Western Sichuan Plateau and analyze their causal mechanisms,precisely reveal the distribution of tourism risks in the study area;2)improve the precision of tourism risk evaluation in scenic areas and analyze the causes and spatial distribution patterns of tourism risks and propose targeted management *** study found that the evaluation results of the four elements of hazard,exposure,vulnerability,and disaster prevention and mitigation capacity on the Western Sichuan Plateau showed significant spatial variability,depending on the natural conditions and the quantity difference of tourism resources in different *** addition,the tourism risk is low in most areas of the Western Sichuan Plateau,and disaster prevention and mitigation capacity is higher in areas with high tourism risk where attractions are densely populated and tourism is *** study can provide a reference for future analyses of tourism risks in mountainous tourist areas such as in China and worldwide.

关键词： Tourism risks Risk assessment Risk sources Fishbone diagram Western Sichuan Plateau

Preliminary Research on a Mesenchymal Stem Cell-model for Screening Traditional Chinese Medicines

在线全文

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2010年第6期26卷 986-990页

作者： FAN xue-mei LI xue WANG Yi-ming LIANG Qiong-lin LUO Guo-an School of Pharmacy East China University of Science and Technology Shanghai 200237 P. R. China School of Medicine Tsinghua University Beijing 100084 P. R. China Department of Chemistry Tsinghua University Beijing 100084 P. R. China

The authors focused their attention on the establishment of a mesenchymal stem cell（MSC） model for screening traditional Chinese medicines（TCMs） so as to investigate the effects of Shuanglong Formula（SLF） components（Ginsenosides and salvianolic acids） and ingredients（ginsenoside Rb1 and salvianolic acid B） on cardiomyocyte differentiation from *** SLF components were analyzed and quantified by *** differentiation was induced by culturing MSCs in the induction medium supplemented with SLF ingredients,SLF components,5-azacytidine（5-aza）,5-aza＋SLF ingredients and 5-aza＋SLF components,respectively,for up to 30 d,and evulated by the expression of Cardiac-specific myosin heavy chain（MHC） and troponin I（TnI） via immunofluoresent *** growth rate and changed morphology were observed during cardiomyocyte *** 20 d of induction,differentiating MSCs were positive for MHC and TnI *** effects of SLF components were better than those of SLF *** together,SLF can induce the differentiation of MSCs into cardiomyogenic cells in vitro,and MSCs can be used as a powerful tool for screening TCMs.

关键词： Bone marrow mesenchymal stem cell Screening model Shuanglong Formula Immunofluoresent staining

Production and application of a novel bioflocculant by multiple-microorganism consortia using brewery wastewater as carbon source

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2007年第6期19卷 667-673页

作者： ZHANG Zhi-qiang lin Bo XIA Si-qing WANG xue-jiang YANG A-ming State Key Laboratory of Pollution Control and Resource Reuse College of Environmental Science and Engineering Tongji University Shanghai 200092 China College of Environmental -Science and Engineering Nanchang University Nanchang 330031 China

The flocculating activity of a novel bioflocculant MMF1 produced by multiple-microorganism consortia MM1 was investigated. MM1 was composed of strain BAFRT4 identified as Staphylococcus sp. and strain CYGS1 identified as Pseudomonas sp. The flocculating activity of MMF1 isolated from the screening medium was 82.9%, which is remarkably higher than that of the bioflocculant produced by either of the strains under the same condition. Brewery wastewater was also used as the carbon source for MM1, and the cost-effective production medium for MM1 mainly comprised 1.0 L brewery water （chemical oxygen demand （COD） 5000 mg/L）, 0.5 g/L urea, 0.5 g/L yeast extract, and 0.2 g/L （NH4）2SO4. The optimal conditions for the production of MMF1 was inoculum size 2%, initial pH 6.0, cultivating temperature 30℃, and shaking speed 160 r/min, under which the flocculating activity of the MMF1 reached 96.8%. Fifteen grams of purified bioflocculant could be recovered from 1.0 L of fermentation broth. MMF1 was identified as a macromolecular substance containing both protein and polysaccharide. It showed good flocculating performance in treating indigotin printing and dyeing wastewater, and the maximal removal efficiencies of COD and chroma were 79.2% and 86.5%, respectively.

关键词： bioflocculant multiple-microorganism consortia brewery wastewater carbon source indigotin printing and dyeing wastewater

Preface to the Special Issue on the “Observation,Prediction and Analysis of severe Convection of China”(OPACC) National “973” Project

在线全文

学校读者我要写书评

暂无评论

Advances in Atmospheric Sciences 2016年第10期33卷 1099-1101页

作者： ming xue School of Atmospheric Sciences Nanjing UniversityNanjingChina Center for Analysis and Prediction of Storms and School of Meteorology University of Oklahoma

China is a country that is frequently affected by severe convective weather. Here, severe convective weather mainly refers to intense local heavy precipitation, thunderstorm-induced gale-force winds including those from tornadoes and downbursts, and hail and lightning. These types of severe weather are usually small in spatial scale and rapid in their development, and are therefore difficult to capture by observational networks and are poorly resolved in typical operational numerical weather prediction （NWP） models. Furthermore, many of the important dynamic and physical processes involved are not well understood. Within China, the impacts of severe convective weather rank only after those of landfalling typhoons and widespread heavy precipitation and flooding. Studies （e.g., Zhang and Zhai, 2011） have shown tendencies for an increased frequency in short-duration extreme precipitation during the past several decades over most of eastern China, where the population is most dense. An in-depth understanding of severe convective weather in China, as well as being able to accurately predict it, is clearly of great importance.

关键词： Project National Preface to the Special Issue on the

Discovery of β-Dihydroagarofuran-Type Sesquiterpenoids from the Leaves of Tripterygium wilfordii with Neuroprotective Activities

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Chemistry 2021年第2期39卷 337-344页

作者： Shuhui Dong Bin lin Xiaobian xue ming Bai Xiaoxiao Huang Shaojiang Song Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research&Development Liaoning ProvinceSchool of Traditional Chinese Materia MedicaShenyang Pharmaceutical UniversityShenyangLiaoning110016 China School of Pharmaceutical Engineering Shenyang Pharmaceutical UniversityShenyangLiaoning110016 China

Nine undescribed dihydro-β-agarofuran sesquiterpenoid derivatives(1—9),along with a known analogue(10),were obtained from the leaves of Tripterygium *** gross structures were determined via extensive spectroscopic data,and the absolute configurations were elucidated by means of single-crystal X-ray diffraction analysis and electron circular dichroism(ECD)techniques,which include ECD exciton chirality,octant rule of saturated cyclohexanone and comparison between the experimental and calculated ECD *** the isolated compounds were tested for their neuroprotective activities against H2O2-induced cell injury in human neuroblastoma SH-SY5Y *** 5 and 6 improved cell viability by 16.15%and 15.12%compared with the H2O2 treated group at 25μmol·L^(-1),respectively.

关键词： Tripterygium wilfordii Terpenoids Biological activity Structure elucidation Single-crystal X-ray diffraction

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

学校体育课程资源的开发现状

体育科学研究 2008年第3期12卷 66-68页

作者：谢成超杨学明李秀林西南石油大学体育系四川成都610500

为了解我国学校体育课程资源开发现状,进一步贯彻执行教育部的"三级课程管理"政策,采用文献资料法、专家访谈法、逻辑分析法对学校体育课程资源的概念、分类、选择、认识、开发途径等方面进行分析。阐释了学校体育课程资源应从学校体育... 详细信息

为了解我国学校体育课程资源开发现状,进一步贯彻执行教育部的"三级课程管理"政策,采用文献资料法、专家访谈法、逻辑分析法对学校体育课程资源的概念、分类、选择、认识、开发途径等方面进行分析。阐释了学校体育课程资源应从学校体育课程内容资源、校外体育资源、场地器材资源整合、体育信息资源等几方面开发的主要内容及注意事项。

关键词：学校体育课程资源体育课程开发