检索结果-南通市图书馆

RO-heparin Inhibits L-Selectin-mediated Neutrophils Adhesion to Vascular Endothelium Under Flow Conditions

在线全文

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2006年第3期22卷 302-307页

作者： CHEN Zhi-hong XU Li BA xue-qing zeng Xian-lu Institute of Genetics and Cytology Northeast Normal University Changchun 130024 P. R. China School of Life Science Mudanjiang Medical University Mudanjiang 157011 P. R. China Biology Section College of Changchun Traditional Chinese Medicine Changchun 130017 P. R. China

Selectins are carbohydrate-binding cell adhesion molecules that play a major role in the initiation of inflammatory responses. Accumulaed evidence has suggested that heparin＇s anti-inflammatory effects are mainly mediated by blocking L-or P-selectin-initiated cell adhesion. Recently, we have reported that periodate-oxidized, borohydridereduced heparin （RO-heparln） can inhibit P-selectin-mediated acute inflammation. Here we further examined the effect of RO-heparin on the adhesion of L-selectin-mediated leukocytes to vascular endothelium under flow conditions in vivo and in vitro. The results show that RO-heparin with a low anticoagulant activity can effectively reduce leucocyte roiling on thioglycoUate-induced rat mesenterlc venules and L-selectin-metadiated neutrophil roiling on TNF-α-induced human umbilical vein endothelial cells（HUVECs） under flow conditions. Our findings suggest that the effect of RO-heparin on inflammatory responses is mainly a result of its inhibiting the interaction between P- or L-selectin and its ligands. The findings also suggest that RO-heparin may be useful in preventing inflammation diseases.

关键词： RO-heparin Neutrophils adhesion L-selectin Human umbilical vein endothelial cells (HUVECs)

Formation of topological domain walls and quantum transport properties of zero-line modes in commensurate bilayer graphene systems

在线全文

学校读者我要写书评

暂无评论

Frontiers of physics 2022年第6期17卷 95-105页

作者： Junjie zeng Rui xue Tao Hou Yulei Han Zhenhua Qiao ICQD Hefei National Laboratory for Physical Sciences at MicroscaleCAS Key Laboratory of Strongly-Coupled Quantum Matter PhysicsDepartment of PhysicsUniversity of Science and Technology of ChinaHefei 230026China Department of Physics Fuzhou UniversityFuzhou 350108China

We study theoretically the construction of topological conducting domain walls with a finite width between AB/BA stacking regions via finite element method in bilayer graphene systems with tunable commensurate twisting *** find that the smaller is the twisting angle,the more significant the lattice reconstruction would be,so that sharper domain boundaries declare their *** subsequently study the quantum transport properties of topological zero-line modes which can exist because of the said domain boundaries via Green’s function method and Landauer–Büttiker formalism,and find that in scattering regions with triintersectional conducting channels,topological zero-line modes both exhibit robust behavior exemplified as the saturated total transmission Gtot≈2e_(2)/h and obey a specific pseudospin-conserving current partition law among the branch transport *** former property is unaffected by Aharonov–Bohm effect due to a weak perpendicular magnetic field,but the latter is *** from our genuine bilayer hexagonal system suggest a twisting angle aroundθ≈0.1°for those properties to be expected,consistent with the existing experimental reports.

关键词： twistronics lattice reconstruction topological domain wall zero-line mode quantum transport

Water lubrication of graphene oxide-based materials

在线全文

学校读者我要写书评

暂无评论

Friction 2022年第7期10卷 977-1004页

作者： Shaoqing xue Hanglin LI Yumei GUO Baohua ZHANG Jiusheng LI Xiangqiong zeng Laboratory for Advanced Lubricating Materials Shanghai Advanced Research InstituteChinese Academy of SciencesUniversity of Chinese Academy of SciencesShanghai 201210China School of Environmental and Chemical Engineering Shanghai UniversityShanghai 200444China Key Laboratory for Advanced Materials School of Chemistry and Molecular EngineeringEast China University of Science and TechnologyShanghai 200237China

Water is as an economic,eco-friendly,and efficient lubricant that has gained widespread attention for *** graphene oxide(GO)-based materials can improve the lubricant efficacy of water lubrication due to their outstanding mechanical properties,water dispersibility,and broad application *** this review,we offer a brief introduction about the background of water lubrication and ***,the synthesis,structure,and lubrication theory of GO are *** attention is focused on the relationship between pH,concentration,and lubrication efficacy when discussing the tribology behaviors of pristine *** compounding or reacting GO with various modifiers,amounts of GO-composites are synthesized and applied as lubricant additives or into frictional pairs for different usage *** various strategies of GO-composite generate interesting effects on the tribology *** application cases of GO-based materials are described in water lubrication,including metal processing and *** advantages and drawbacks of GO-composites are then *** development of GO-based materials for water lubrication is described including some challenges.

关键词： tribology water lubrication graphene oxide(GO)

In-situ generation of platinum nanoparticles on LaCoO_(3) matrix for soot oxidation

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Rare Earths 2022年第6期40卷 888-896,I0002页

作者： Hanwen Xu Lirong zeng Lan Cui Wei Guo Cairong Gong Gang xue Institute of New Energy School of Materials Science and EngineeringTianjin UniversityTianjin 300072China Center of Analysis Tianjin UniversityTianjin 300072China Key Laboratory of Special Functional Materials for Ecological Environment and Information of Ministry of Education Hebei University of TechnologyTianjin 300132China

The LaCo_(0.94)Pt_(0.06)O_(3) catalyst is reduced under 5% H_(2)/Ar at different temperatures to get Pt/LaCoO_(3) with high catalytic activity for soot *** electron microscopy(TEM),scanning electron microscopy(SEM),X-ray diffraction(XRD),Brunauer-Emmett-Teller method(BET),X-ray photoelectron spectroscopy(XPS),H_(2)-temperature programmed reduction(H_(2)-TPR),O_(2)-temperature programmed desorption(O_(2)-TPD) and thermogravimetric analysis(TGA) were used to study the physicochemical properties of the *** and TEM results indicate that Pt nanoparticles(<10 nm) are grown homogeneously on the surface of the LaCoO_(3) matrix after in-situ *** shows that the reduced catalyst has a high symmetrical *** results indicate that all reduced catalysts exhibit an excellent activity,especially the catalyst reduced at 350℃(T_(10)=338℃,T_(50)=393℃,T_(90)=427℃).And perovskite is the primary active *** to XPS study,the high symmetrical structure benefits the mobility of oxygen vacancy,and Pt nanoparticles induce the oxygen vacancy to move to its adjacent situation,resulting in more adsorbed oxygen on the surface of the reduced catalyst and increasing the *** possible reaction principle is also proposed.

关键词： Perovskite In-situ reduction Pt nanoparticles Soot oxidation Rare earths

Distributed Dispatch of Multiple Energy Systems Considering Carbon Trading

在线全文

学校读者我要写书评

暂无评论

CSEE Journal of Power and Energy Systems 2023年第2期9卷 459-469页

作者： Yue Xiang Mengqiu Fang Junyong Liu Pingliang zeng Ping xue Gang Wu College of Electrical Engineering Sichuan UniversityChengdu 610065China School of Automation Hangzhou Dianzi UniversityHangzhou 310018China State Grid Sichuan Technical Training Center Chengdu 610072China State Grid Sichuan Economic Research Institute Chengdu 610065China

As an integrated carrier of energy production,transmission,distribution,conversion,storage,and utilization,multiple energy systems(MESs)have significant low-carbon *** paper proposes a hierarchical distributed dispatch model of MESs considering carbon trading,which is composed of the lower autonomous operation level of each MES and the upper coordinated control *** carbon emission sources are considered,including combined heat and power(CHP)units,gas boilers,and power to gas(P2G)*** transactive control(TC)mechanism is used to solve the model by introducing a virtual price *** the case study based on a 3-MES system,the effectiveness of the proposed distributed method is proved by comparison with a centralized ***,the impacts of different carbon prices on MESs with different resource endowments are analyzed from the aspects of scheduling results,carbon emissions,clean energy consumption rate,and comprehensive operating costs.

关键词： Carbon trading distributed optimal dispatch transactive control multiple energy systems

Plasmonic silver/silver oxide nanoparticles anchored bismuth vanadate as a novel visible-light ternary photocatalyst for degrading pharmaceutical micropollutants

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2020年第10期32卷 21-32页

作者： Shengyan Pu zeng Yang Jing Tang Hui Ma Shengyang xue Yingchen Bai State Key Laboratory o f Geohazard Prevention and Geoenvironment Protection Chengdu University of TechnologyChengdK 610059SichitcmChina State Key Laboratory of Environmental Criteria and Risk Assessment Chinese Research Academy of Environmental SciencesBeijing 100012China Department of Plant and Environmental Sciences Uniuersity of CopenhagenThorvaldsensvej 401871 FrederiksbergDenmark

The degradation of pharmaceutical micropollutants is an intensifying environmental problem and synthesis of efficient photocatalysts for this purpose is one of the foremost challenges ***,this study was conducted to develop novel plasmonic Ag/Ag2O/BiVO4 nanocomposite photocatalysts by simple precipitation and thermal decomposition methods,which could exhibit higher photocatalytic activity for mineralized pharmaceutical *** the different treatments,the best performance was observed for the Ag/Ag2O/BiVO4 nanocomposites (5 wt.%;10 min’s visible light irradiation)which exhibited 6.57 times higher photodegradation rate than the pure ***,the effects of different influencing factors on the photodegradation system of tetracycline hydrochloride (TC-HCl) were investigated and the feasibility for its practical application was explored through the specific light sources,water source and cycle *** mechanistic study demonstrated that the photogenerated holes (h^+),superoxide radicals (·O2^-)and hydroxyl radicals (·OH) participated in TC-HCl removal process,which is different from the pure BiVO4 reaction ***,the present work can provide a new approach for the formation of novel plasmonic photocatalysts with high photoactivity and can act as effective practical application for environmental remediation.

关键词： Ag/Ag_2O/BiVO_4 Tetracycline hydrochloride Photocatalytic degradation Pharmaceutical micropollutants

Achieving a remarkable low-temperature tensile ductility in a high-strength tungsten alloy

在线全文

学校读者我要写书评

暂无评论

Tungsten 2024年第1期6卷 150-161页

作者： Xiang Cheng Zhuo-ming Xie xue-Feng Xie Long-Fei zeng Rui Liu Jun-Feng Yang xue-Bang Wu Xian-Ping Wang Chang-Song Liu Qiang-Feng Fang Key Laboratory of Materials Physics Institute of Solid State PhysicsHFIPSChinese Academy of SciencesHefei 230031China University of Science and Technology of China Hefei 230026China Faculty of Materials Metallurgy and Chemistry Jiangxi University of Science and TechnologyGanzhou 341000China

Hot-swaging yields a high ultimate tensile strength of 712 MPa but a limited tensile ductility with the total elongation of3.6%at a testing temperature of 200℃in a representative W-0.5wt.%ZrC *** this work,the evolution of Vickers microhardness with annealing temperatures is investigated in detail,which contributes to a rough index chart to guide the search for an optimized post-annealing *** the post-annealing around 1300℃,an outstanding tensile ductility at200℃,including a uniform elongation of 14%and a total elongation of~25%,has been achieved without the sacrifice of its *** evolution of dislocations and grain structures with the annealing temperatures accessed through backscattered scanning electron microscope and transmission electron microscope analysis reveals that the improved low-temperature tensile ductility has resulted from the reduction of residual dislocations and dislocation tanglement via the static recovery,which provides more room to accommodate dislocations,and hence stronger strain hardening ability and tensile ductility.

关键词： Tungsten Low-temperature ductility Annealing Dislocations

Development of Future Generations:Oriented Virtual Negotiation Support System for Intergenerational Conflict

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Population,Resources and Environment 2008年第3期6卷 63-72页

作者： zeng Weihua Zhong Xiaohong xue Pengli State Key Laboratory of Water Environment Simulation School of Environment Beijing Normal University Beijing 100875 China China＇s Academy of Environmental Planning State Environmental Protection Administration Beijing 100012 China

Intergenerational conflict coordination is the fundamental requirement and core of sustainable development. In this paper, through the analysis of the future generations-oriented management mechanisms for intergenerational conflict, the idea of mechanisms and institution building for the coordination and management of intergenerational conflict is put forward. Furthermore, the future generations-oriented virtual negotiation support system (NSS) for intergenerational conflict is developed, built on the analysis of the process simulation of intergenerational wealth transfer, intergenerational equilibrium allocation of resources, and strategies for the mitigation and avoidance of intergenerational conflict, through the application of advanced IT technology. The virtual NSS for intergenerational conflict is helpful to the practical application of the sustainable development theory; on the other hand, it can be applied directly to the intergenerational equilibrium allocation of resources, national economic accounting, formulation of sustainable development strategies and other urgent national economic and social development issues. Finally, the sustainable development theory can be enriched and extended. Therefore, the development of the future generations-oriented virtual NSS for intergenerational conflict has certain theoretical and practical effects on the theory of sustainable development.

关键词： intergenerational conflict, virtual negotiation support system (NSS), agent of future generations intergenerational equilibrium allocation of resources and wealth, process simulation of intergenerational resources consumption and wealth transfer

非洲猪瘟病毒p34蛋白重组纳米颗粒的制备及免疫原性评价

在线全文

学校读者我要写书评

暂无评论

农业生物技术学报 2025年第1期33卷 228-236页

作者：张荣茹毅蒋成辉张越赵冬梅郝荣增李亚军郑海学刘学荣杨进才安兰芳魏彦明甘肃农业大学动物医学院中国农业科学院兰州兽医研究所/动物疫病防控全国重点实验室中农威特生物科技股份有限公司

铁蛋白纳米颗粒具有可展示多抗原的表面，能更好的促进细胞摄取和抗原呈递，进而增强免疫效力而被广泛应用于疫苗研究。本研究旨在利用铁蛋白制备携带非洲猪瘟病毒(African swine fever virus,ASFV) p34蛋白的纳米颗粒抗原，并评价其免... 详细信息

铁蛋白纳米颗粒具有可展示多抗原的表面，能更好的促进细胞摄取和抗原呈递，进而增强免疫效力而被广泛应用于疫苗研究。本研究旨在利用铁蛋白制备携带非洲猪瘟病毒(African swine fever virus,ASFV) p34蛋白的纳米颗粒抗原，并评价其免疫原性，为非洲猪瘟纳米疫苗研究提供参考。首先，将编码p34蛋白和SpyTag(ST)标签的基因序列串联后插入pET-28a(+)载体得到pET-p34-ST重组质粒，将编码Spycatcher(SC)与铁蛋白(ferritin, F)的基因序列串联后插入pET-28a(+)载体得到pET-SC-F重组质粒，并分别在大肠杆菌(Escherichia coli)中诱导表达。然后通过亲和层析法纯化2种重组蛋白p34-ST和SC-F后，进行体外偶联得到重组纳米颗粒F-p34。利用SDS-PAGE、Western blot、动态光散射(dynamic light scattering, DLS)、投射电子显微镜(transmission electron microscopy, TEM)等方法对制备的F-p34进行鉴定和形态表征，最后通过免疫BALB/c小鼠(Mus musculus)进行体内免疫原性评价。结果显示，本研究成功设计并构建了pET-28a-p34-ST和pET-28a-SC-F原核表达载体，经过体外表达、纯化和偶联，成功制备出偶联非洲猪瘟病毒p34蛋白的铁蛋白纳米颗粒F-p34，其与ASFV阳性血清能够发生特异性反应，DLS和TEM体外表征发现，F-p34粒径大约为21 nm，且具有均一的纳米颗粒结构；F-p34免疫小鼠后7 d即可诱导机体产生特异性免疫应答，在42 d时抗体滴度达到最高且显著高于单体抗原p34免疫组(P<0.05)。Fp34免疫组脾淋巴细胞的增殖水平和血清中细胞因子白细胞介素4(interleukin 4, IL-4)、IL-10、IL-2和干扰素γ(interferon, IFN-γ)的分泌水平显著高于p34免疫组(P<0.05)。综上，本研究成功制备了具有良好免疫原性的携带非洲猪瘟病毒p34蛋白的纳米颗粒抗原，拓宽了非洲猪瘟亚单位疫苗的研究思路。

关键词：非洲猪瘟病毒(ASFV) p34蛋白铁蛋白纳米颗粒偶联免疫原性