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International Journal of Ophthalmology(English edition) 2022年第10期15卷 1591-1597页

作者： Yin-Hao Wang Jing Zhong xue-min li Department of Ophthalmology Peking University Third HospitalBeijing 10091China Beijing Key Laboratory of Restoration of Damaged Ocular Nerve Peking University Third HospitalBeijing 10091China Education Department Peking University Third HospitalBeijing 10091China

AIM: To explore the changes in lens thickness and density with ***: A Chinese population-based retrospective study was performed. A total of 497 individuals(490 right eyes and 495 left eyes), ranging from 3 to 69 years old were included. Lens images obtained from IOL Master 700 were used to measure lens thickness and density. Piecewise regression model was chosen to illustrate the relationship of lens thickness and density with ***: The proportion of people aged 3-18, 19-40, over 40 was 38.6%, 50.9% and 10.5% respectively. The whole lens thickness decreased with age during the first 7 years of life, kept stable from 8 to 16 years old, and then increased at the rate of about 27 μm per year. The thickness of the lens cortex and nucleus tended to decrease first and then increase with age, which was dependent on age stages. The whole lens density also decreased with age until 7 years old. The increasing rate of lens density was different in different age groups. The whole lens density increased rapidly from 7 to 22 years old and slowed down after 22 years old. Similarly, the changing tendency of lens cortical and nuclear density differed in different age phases. CONCLUSION: Both lens thickness and density are significantly associated with age, whereas they do not change linearly with age. Moreover, it is necessary to increase the population over 40 years old and conduct further research.

关键词： lens thickness lens density age staged growth

Applications of dynamic visual acuity test in clinical ophthalmology

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International Journal of Ophthalmology(English edition) 2021年第11期14卷 1771-1778页

作者： Ting-Yi Wu Yue-Xin Wang xue-min li Department of Ophthalmology Peking University Third HospitalBeijing 100191China Beijing Key Laboratory of Restoration of Damaged Ocular Nerve Peking University Third HospitalBeijing 100191China

Dynamic visual acuity test(DVAT)plays a key role in the assessment of vestibular function,the visual function of athletes,as well as various ocular *** the visual pathways conducting dynamic and static signals are different,DVATs may have potential advantages over the traditional visual acuity tests commonly used,such as static visual acuity,contrast sensitivity,and static ***,we provide a review of commonly applied DVATs and their several uses in clinical *** data indicate that the DVAT has its unique clinical significance in the evaluation of several ocular disorders.

关键词： dynamic visual acuity test cataract dizziness optic neuritis glaucoma

The Impact of Aqueous Medium on Gas Yields and Kinetic Behaviors of Hydrogen Isotope Fractionation during Organic Matter Thermal Degradation

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Acta Geologica Sinica(English Edition) 2011年第6期85卷 1466-1477页

作者： LU Shuangfang WANG min xue Haitao li Jijun CHEN Fangwen XU Qingxia Northeast Petroleum University Heilongjiang Province 163318 China

In order to recognize the impact of aqueous medium on gas yields and the kinetic behaviors of hydrogen isotope fractionation during organic matter thermal degradation, the gold tube apparatus was used to conduct thermal simulation experiments by mixing the nC18 with the water of different properties and proportions. The yields of natural gas components, the relation among hydrogen isotope composition of each component and the experimental temperatures vs. heating rates have been obtained, and the results indicate that under the higher temperature conditions, the hydrous experiment has obvious impact on gas yields, such as when more water is added, higher amounts of hydrocarbon gas and H2 are yielded, and the existence of water obviously prolongs the temperature interval with the existence of heavy hydrocarbon gas. It also shows that the hydrogen isotope of hydrocarbon gas generated by the hydrous experiment is obviously lighter than that generated by the anhydrous experiment, and with the increasing amount of added water, the δD value of hydrocarbon gas gradually decreases. Compared with gas yields, the variation of δD value is more sensitive to aqueous medium in the thermal simulation experiment. However, compared with the amount of the added water, the aqueous medium property has smaller impact on the gas yields, which still shows the inherit effect on hydrogen isotope composition of aqueous medium. Through the model simulation and the isotope fractionation behavior analysis, it is validated that the hydrogen isotope fractionation process can be well described by the chemical kinetic model. The difference of reaction fraction of normal methane and D-containing methane is large, corresponding to the same activation energy. The content of normal methane is obviously higher in the part with lower activation energy, while the content of D-containing methane is higher in the part with higher activation energy. Therefore, it will result in larger hydrogen isotope fracti

关键词： hydrogen isotope fractionation chemical kinetics nC18 gas generation hydrous experiment

Perioperative management by WeChat under the haze of COVID-19

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International Journal of Ophthalmology(English edition) 2020年第7期13卷 1161-1163页

作者： Yin-Hao Wang li-ming Zhao Zi-Yuan liu xue-min li Department of Ophthalmology Peking University Third HospitalBeijing 100191China Beijing Key Laboratory of Restoration of Damaged Ocular Nerve Peking University Third HospitalBeijing 100191China Department of Ophthalmology Beijing Fengtai HospitalBeijing 100071China

Dear Editor,We come up with an e-health perioperative management strategy based on We Chat during the outbreak of *** novel coronavirus pneumonia called coronavirus disease 2019(COVID-19)was of clustering onset and ab... 详细信息

关键词： respiratory distress acute

Hydrogel dressings on neurotrophic keratitis in an experimental animal model

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International Journal of Ophthalmology(English edition) 2024年第8期17卷 1396-1402页

作者： Hua-Qin Xia Xiao-Dan Jiang Yi-Fan Song xue-min li Yan-Jie Tian Department of Ophthalmology Peking University Third HospitalBeijing 100191China Beijing Key Laboratory of Restoration of Damaged Ocular Nerve Peking University Third HospitalBeijing 100191China

AIM:To investigate the therapeutic effects of hydrogel dressings on neurotrophic keratitis in ***:Male Wistar rats,aged 42–56d,were randomly divided into control,experimental,and treatment groups,each consisting of five *** experimental and treatment groups underwent neurotrophic keratitis modeling in both *** successful modeling,biomedical hydrogels formed with polyvinyl alcohol and polyvinyl pyrrolidone were used in treatment group for *** irritation response and keratitis index scores,Schirmer’s test,tear film break-up time(BUT),sodium fluorescein staining,and hematoxylin and eosin(HE)staining were used to evaluate the effectiveness of the ***:The neurotrophic keratitis model was successfully established in rats with severe ophthalmic nerve injury,characterized by keratitis,ocular irritation,reduced tear secretion measured by decreased BUT and Schirmer test values,corneal epithelial loss,and disorganized collagen fibers in the stromal *** treatment with hydrogel dressings,significant improvements were observed in keratitis scores and ocular irritation symptoms in model *** the recovery of tear secretion,as measured by the Schirmer’s test,did not show statistical differences,BUT was significantly *** staining confirmed a reduction in the extent of corneal epithelial loss after *** staining revealed the restoration of the structural disorder in both the epithelial and stromal layers to a certain ***:Hydrogel dressing reduces ocular surface irritation,improves tear film stability,and promotes the repair and restoration of damaged epithelial cells by maintaining a moist and clean environment on the ocular surface in the rat model.

关键词： neurotrophic keratitis hydrogel corneal epithelial cells rat

Panscleritis After Blunt Ocular Trauma in A Child with Epididymitis

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Chinese Medical Sciences Journal 2023年第1期38卷 57-61页

作者： Yi-Nan liu Yi-Ning Guo Yi-Fan Song Yan-Jie Tian xue-min li Department of Ophthalmology Peking University Third HospitalBeijing 100191China Beijing Key Laborory of Restoration of Damaged Ocular Nerve Beijing 100191China

We reported an 8-year-old boy with panscleritis in left eye and right epididymitis after falling on the *** diagnosis played a key role in this *** examinations ruled out systemic autoimmune diseases,tumors,and infections as the cause of scleritis and suggested that the disease was caused by a local delayedtype hypersensitivity(DTH)induced by ocular trauma and was ***,the right epididymitis was *** conditions were treated successfully using steroids and antibiotics,***,early etiologic diagnosis and reasonable treatment are crucial to prevent visual loss.

关键词： panscleritis blunt ocular trauma optic neuropathy delayed-type hypersensitivity case report

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International Journal of Ophthalmology(English edition) 2022年第7期15卷 1180-1189页

作者： Hua-Qin Xia Jia-Rui Yang Ke-Xin Zhang Rui-Lan Dong Hao Yuan Yu-Chen Wang Hong Zhou xue-min li Department of Ophthalmology Peking University Third HospitalBeijing 100191China State Key Laboratory of Natural and Biomimetic Drugs Department of PharmacologySchool of Basic Medical SciencesPeking University Health Science CenterBeijing 100191China

Diabetic retinopathy(DR)is one of the most common complications of diabetes and major cause of blindness among people over 50 years *** studies showed that the vascular endothelial growth factor(VEGF)played a central role in the pathogenesis of DR,and application of anti-VEGF has been widely acknowledged in treatment of DR targeting retinal ***,anti-VEGF therapy has several limitations such as drug *** is essential to develop new drugs for future clinical *** vitreous takes up 80%of the whole globe volume and is in direct contact with the retina,making it possible to explore the pathogenesis of DR by studying related factors in the *** article reviewed recent studies on DR-related factors in the vitreous,elaborating the VEGF upstream hypoxia-inducible factor(HIF)pathway and downstream pathways phosphatidylinositol diphosphate(PIP2),phosphoinositide-3-kinase(PI3 K),and mitogenactivated protein kinase(MAPK)***,factors other than VEGF contributing to the pathogenesis of DR in the vitreous were also summarized,which included factors in four major systems,kallikrein-kinin system such as bradykinin,plasma kallikrein,and coagulation factor XII,oxidative stress system such as lipid peroxide,and superoxide dismutase,inflammation-related factors such as interleukin-1β/6/13/37,and interferon-γ,matrix metalloproteinase(MMP)system such as MMP-9/***,we also introduced other DR-related factorssuch as adiponectin,certain specific amino acids,noncoding RNA and renin(pro)receptor in separate studies.

关键词： diabetic retinopathy vitreous molecular pathway vascular endothelial growth factor

An Analysis of the Correlation between the Economic Barometer and the Postal Service

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The Journal of China Universities of Posts and Telecommunications 2002年第3期9卷 74-78页

作者： liU Hong wei, xue Feng min, li xue dong (Shijiazhuang Postal College, Shijiazhuang 050021, P.R. China) Shijiazhuang Postal College Shijiazhuang 050021 P.R. China

There are many economic factors that can influence the postal market. In thispaper, by adopting the method of quantitative analysis, the author analyse exhaustively theeconomic factors that influence the postal market... 详细信息

关键词： economic factors postal market partial correlation

Diagnosis and treatment of diverticulum of the uterus in pregnancy through hysteroscopy and methotrexate: a case report

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Journal of Medical Colleges of PLA(China) 2010年第2期25卷 119-121页

作者： Pan Qiong xue min li Xiang Wan Yajun Cheng Chunxia Department of Obstetrics and Gynecology Third Xiangya Hospital Central South University Changsha 410013 China

A 27-year-old patient was diagnosed by hysteroscopy with uterine diverticulum in pregnancy and admitted to the hospital. Under the guidance of hysteroscopy combined with methotrexate, the scraping of the uterus was done and operation successfully completed. The management of this case showed that hysteroscopy was a kind of valuable approach to the diagnosis and treatment of uterine diverticulum and curettage of the uterus under hysteroscope combined with drug was a safe, effective and conservative treatment.

关键词： Hysteroscopy Diverticulum of the uterus in pregnancy Methotrexate