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Journal of Clinical and Nursing Research 2024年第6期8卷 21-25页

作者： Juan Xu Shanshan Zhang Guohui Zhang Lihua huang Qinghua Yi Department of Endocrinology and Nephrology People's Hospital of Guandu DistrictKunmingYunnan 650200China

Objective:To evaluate the efficacy and safety of different basal insulins in the treatment of type 2 diabetes mellitus(T2DM).Methods:The current research progress on different basal insulins was evaluated,with efficacy indicators including fasting plasma glucose(FPG)and glycated hemoglobin(HbAic),and safety indicators focusing mainly on weight change and the incidence of ***:Several different basal insulins showed similar metabolic control effects in terms of fasting plasma glucose and glycated ***,the risk of hypoglycemia was lower with insulin glargine 300(Glar-300),insulin degludec 100(Deg-100),and insulin degludec 200(Deg-200)compared to insulin glargine 100(Glar-100).Additionally,Glar-300 had the least impact on ***:For the treatment of T2DM,different basal insulins have similar therapeutic effects,but there are differences in the incidence of hypoglycemic events and their impact on *** insulin selection and dosage adjustments should be made based on the different patient groups.

关键词： Basal insulin Type 2 diabetes mellitus Hypoglycemia

基于开放三维生态足迹的中国黑土区耕地可持续利用分析与评价

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资源科学 2024年第5期46卷 1018-1031页

作者：郑皓洋黄颖利东北林业大学经济管理学院哈尔滨150040

[目的]本文旨在对黑土区耕地可持续利用进行分析与评价,探讨耕地自然资本使用情况,为推动黑土区耕地资源合理利用提供政策建议。[方法]本文基于2009-2016年中国黑土区耕地利用过程中的作物产量和人口经济等数据,通过构建“开放”三维生... 详细信息

[目的]本文旨在对黑土区耕地可持续利用进行分析与评价,探讨耕地自然资本使用情况,为推动黑土区耕地资源合理利用提供政策建议。[方法]本文基于2009-2016年中国黑土区耕地利用过程中的作物产量和人口经济等数据,通过构建“开放”三维生态足迹模型以及综合可持续利用指数来对耕地可持续利用进行分析。[结果](1)从调整后的生态足迹来看,在2009-2016年黑土区人均耕地资源有0.084 hm^(2)由外地居民占用,本地居民占用0.208 hm^(2)。(2)从自然资本流量角度来看,黑土区全域耕地自然资本流量的人均占用量在0.199 hm^(2)左右,最高值为2016年的0.200 hm^(2);从自然资本存量角度来看,2009-2016年黑土区耕地足迹深度先增长至1.114后波动下降至1.071。(3)黑土区耕地可持续利用综合指数基本在0.55上下浮动;分省份来看,除辽宁外,其他省份均处在0.45~0.56之间。[结论]黑土区承载了部分耕地转移压力,其自然资本经历了存量保持、存量消耗和存量恢复的三阶段演进路径,黑土区及各省份的耕地可持续利用程度不高,还有很大的政策提升空间。本文可为黑土区耕地资源后续可持续利用提供依据及政策启示。

关键词：黑土区耕地可持续利用生态足迹自然资本生态承载力

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Demonstration of 10 Gbps satellite-to-ground laser communications in engineering

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The Innovation 2024年第1期5卷 7-8页

作者： Yalin Li Hongqun Zhang Peng huang Guangtong Wan Yu Li Aerospace Information Research Institute Chinese Academy of SciencesBeijing 100094China

In June 2023,researchers at the Aerospace Information Research Institute(AIR)of the Chinese Academy of Sciences undertook a series of experiments on satellite-to-ground laser communication using the Jilin-1 MF02A04(JLMF)satellite and independently developed a 500 mm optical communication ground station(AIROSG),achieving a successful throughput of 10 gigabits per second(Gbps)in the satellite-to-ground optical *** obtained satellite payload data demonstrated good performance and satisfied the requirements of high-standard scientific applications.

关键词： Gbps laser communication

Conservation genomics of the critically endangered Chinese pangolin

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Science China Life Sciences 2024年

作者： Shichao Wei Huizhong Fan Wenliang Zhou Guangping huang Yan Hua Shibao Wu Xiao Wei Yiting Chen Xinyue Tan Fuwen Wei Jiangxi Province Key Laboratory of Conservation Biology College of Forestry Jiangxi Agricultural University Center for Evolution and Conservation Biology Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) Institute of Zoology Chinese Academy of Sciences Guangdong Provincial Key Laboratory of Silviculture Protection and Utilization Guangdong Academy of Forestry School of Life Science South China Normal University Terrestrial Wildlife Rescue and Epidemic Diseases Surveillance Center of Guangxi

The Chinese pangolin(Manis pentadactyla, MP) has been extensively exploited and is now on the brink of extinction, but its population structure, evolutionary history, and adaptive potential are unclear. Here, we analyzed 94 genomes from three subspecies of the Chinese pangolin and identified three distinct genetic clusters(MPA, MPB, and MPC), with MPB further divided into MPB1 and MPB2 subpopulations. The divergence of these populations was driven by past climate change. For MPB2 and MPC, recent human activities have caused dramatic population decline and small population size as well as increased inbreeding, but not decrease in genomic variation and increase in genetic load probably due to strong gene flow; therefore, it is crucial to strengthen in situ habitat management for these two populations. By contrast, although human activities have a milder impact on MPA, it is at high risk of extinction due to long-term contraction and isolation, and genetic rescue is urgently needed. MPB1 exhibited a relatively healthy population status and can potentially serve as a source population. Overall, our findings provide novel insights into the conservation of the Chinese pangolin and biogeography of the mammals of eastern Asia.

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Catalytic conversion of mixed polyolefins under mild atmospheric pressure

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The Innovation 2024年第2期5卷 98-106页

作者： Binzhi Zhao Hui Tan Jie Yang Xiaohui Zhang Zidi Yu Hanli Sun Jialiang Wei Xinyi Zhao Yufeng Zhang Lili Chen Dali Yang Jin Deng Yao Fu Zheng huang Ning Jiao State Key Laboratory of Natural and Biomimetic Drugs School of Pharmaceutical SciencesPeking UniversityBeijing 100191China Beijing National Laboratory for Molecular Sciences College of Chemistry and Molecular EngineeringPeking UniversityBeijing 100871China The Institute for Advanced Studies Wuhan UniversityWuhan 430072China Hefei National Laboratory for Physical Sciences at the Microscale CAS Key Laboratory of Urban Pollutant ConversionAnhui Province Key Laboratory of Biomass Clean EnergyiChEMUniversity of Science and Technology of ChinaHefei 230026China State Key Laboratory of Organometallic Chemistry Chinese Academy of SciencesShanghai 200032China

The chemical recycling of polyolefin presents a considerable challenge,especially as upcycling methods struggle with the reality that plastic wastes typically consist of mixtures of polyethylene(PE),polystyrene(PS),and polypropylene(PP).We report a catalytic aerobic oxidative approach for polyolefins upcycling with the corresponding carboxylic acids as the *** method encompasses three key ***,it operates under atmospheric pressure and mild conditions,using O_(2) or air as the ***,it is compatible with high-density polyethylene,low-density polyethylene,PS,PP,and their ***,it uses an economical and recoverable metal *** has been demonstrated that this approach can efficiently degrade mixed wastes of plastic bags,bottles,masks,and foam boxes.

关键词： mixed Catalytic oxidative

Safety and effect of umbilical cord blood -derived mesenchymal stem cells on apoptosis of human cardiomyocytes

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Journal of Geriatric Cardiology 2010年第2期7卷 110-115页

作者： Shui-Xiang Yang jing-Ling huang Department of Cardiology Beijing Shijitan Hospital Peking University School of Medicine Beoing 100038 China School of Life Science Lanzhou University Lanzhou 730000 Gansu China

Objective To study the safety and effect of the umbilical cord blood （UCB）-derived mesenchymal stem cells （MSCs） on apoptosis of human cardiomyocytes （HCM）. Methods UCB was collected at the time of delivery with informed consent obtained from 10 donors. The UCB-derived MSCs were treated with 5-azaserube （5-AZA） and were further induced to differentiate into cardiomyocytes. Telomerase activity, G-banding patterns of chromosomal karyotypes, tumor formation in nude mice, RT-PCR, and the effect of inhibiting apoptosis of HCM were investigated. Results MSCs derived from UCB were differentiated into cardiomyocytes in vitro, which possessed telomerase activity after 5-AZA induction, and no abnormal chromosomal karyotypes were observed. Expression of p53, cyclin A, cdk2, ~3 -actin, C-fos, h-TERT and c-myc were similar in MSCs before and after 5-AZA treatment. There was no tumor formation in nude mice after injection of UCB-derived MSCs. UCB-derived MSCs significantly inhibited apoptosis of HCM. Conclusion UCB-derived MSCs are a valuable, safe and effective source of cell-transplantation treatment .

关键词： Umbilical cord blood mesenchymal stem cells 5-azaserine human cardiac myocyte apoptosis

Preferences of Bactrocera cucurbitae （ Diptera： Tephritidae） to different colors： a quantitative investigation using virtual wavelength

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昆虫学报 2013年第2期56卷 161-166页

作者： xue huang-Wa WU Wei-Jian Laboratory of Insect Ecology South China Agricultural University Guangzhou 510642 China

利用害虫对不同颜色的趋性进行害虫防治,如利用黄板对实蝇的监测和防治已有很长的历史,然而尚未见把颜色量化进行实蝇对颜色偏嗜性研究的报道。为探明对瓜实蝇Bactrocera cucurbitae最具吸引力的颜色及其虚拟波长,本试验应用DanBruton... 详细信息

利用害虫对不同颜色的趋性进行害虫防治,如利用黄板对实蝇的监测和防治已有很长的历史,然而尚未见把颜色量化进行实蝇对颜色偏嗜性研究的报道。为探明对瓜实蝇Bactrocera cucurbitae最具吸引力的颜色及其虚拟波长,本试验应用DanBruton的虚拟波长与RGB值的函数关系,把RGB值转换为虚拟波长;选择RGB值[(0,213,255),(0,255,146),(54,255,0),(129,255,0),(195,255,0),(255,255,0),(255,190,0)和(255,119,0)]的颜色进行打印,这些颜色对应的虚拟波长分别是480,500,520,540,560,580,560和600nm;在八面体内进行瓜实蝇对8种颜色的偏嗜性试验。结果表明:波长在520～560nm之间对应的颜色对瓜实蝇的吸引率高于其他虚拟波长对应的颜色,而540nm(黄绿色,RGB值为129,255,0)对应的颜色纸对瓜实蝇的吸引率最大。此外田间颜色偏嗜性试验也证实了黄绿色对瓜实蝇有最强的引诱作用。结果说明,黄绿色(虚拟波长540nm)是吸引瓜实蝇的关键颜色,黄绿色粘虫板可作为监测与防治瓜实蝇的一种有效方法。

关键词：瓜实蝇波长颜色定量调查偏好虚拟实蝇科双翅目

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深部脑刺激在物质成瘾中的研究进展

中国药物依赖性杂志 2024年第2期33卷 96-101,108页

作者：李元荣黄静静王利新王绪轶中南大学湘雅二医院精神卫生研究所长沙410011

近年来,深部脑刺激在成瘾领域的应用越来越广泛,然而其确切的机制尚不清楚。本文对深部脑刺激在酒精使用障碍、阿片类使用障碍、兴奋剂使用障碍中的相关研究进行综述,列举了相关的临床研究及动物实验,总结了深部脑刺激治疗成瘾的可能机... 详细信息

近年来,深部脑刺激在成瘾领域的应用越来越广泛,然而其确切的机制尚不清楚。本文对深部脑刺激在酒精使用障碍、阿片类使用障碍、兴奋剂使用障碍中的相关研究进行综述,列举了相关的临床研究及动物实验,总结了深部脑刺激治疗成瘾的可能机制,并探讨了该技术的未来展望。

关键词：深部脑刺激物质成瘾伏隔核

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Assessing recent recurrence after hepatectomy for hepatitis Brelated hepatocellular carcinoma by a predictive model based on sarcopenia

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World Journal of Gastroenterology 2024年第12期30卷 1727-1738页

作者： Hong Peng Si-Yi Lei Wei Fan Yu Dai Yi Zhang Gen Chen Ting-Ting Xiong Tian-Zhao Liu Yue huang Xiao-Feng Wang Jin-Hui Xu Xin-Hua Luo Department of Infectious Diseases Guizhou Provincial People’s HospitalGuiyang 550002Guizhou ProvinceChina Department of Hepatobiliary Surgery Guizhou Provincial People’s HospitalGuiyang 550002Guizhou ProvinceChina

BACKGROUND Sarcopenia may be associated with hepatocellular carcinoma(HCC)following *** traditional single clinical variables are still insufficient to predict *** still lack effective prediction models for recent recurrence(time to recurrence5 cm(HR=2.222,95%CI:1.285-3.842,P<0.05),and hepatitis B virus DNA level≥2000 IU/mL(HR=2.1,95%CI:1.407-3.135,P<0.05)were independent risk factors associated with postoperative recurrence of *** on the sarcopenia to assess the RFS model of hepatectomy with hepatitis B-related liver cancer disease(SAMD)was established combined with other the above risk *** area under the curve of the SAMD model was 0.782(95%CI:0.705-0.858)in the training cohort(sensitivity 81%,specificity 63%)and 0.773(95%CI:0.707-0.838)in the validation ***,a SAMD score≥110 was better to distinguish the high-risk group of postoperative recurrence of *** Sarcopenia is associated with recent recurrence after hepatectomy for hepatitis B-rel

关键词： Alpha-fetoprotein Hepatitis B virus Hepatectomy Hepatocellular carcinoma Nomogram Predictive models Recurrence Recurrence-free survival Risk factors Sarcopenia

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纯电池动力船舶电气设计关键技术分析

船海工程 2024年第S1期53卷 6-10页

作者：黄少青中国船级社广州分社广州审图中心广州510235

针对纯电池动力船舶的关键电气安全影响因素进行分析,采取相应的技术措施以确保船舶安全。基于中国船级社关于该类船舶规范的最新研究成果,结合当前内河该类船舶的典型设计,对纯电池动力船舶的电气设计难点和要点进行剖析,重点分析和介... 详细信息

针对纯电池动力船舶的关键电气安全影响因素进行分析,采取相应的技术措施以确保船舶安全。基于中国船级社关于该类船舶规范的最新研究成果,结合当前内河该类船舶的典型设计,对纯电池动力船舶的电气设计难点和要点进行剖析,重点分析和介绍该类船舶的锂电池船用和直流综合电力系统设计的电气关键安全技术要求。从目前内河纯电池动力船舶的营运情况看,提出的关键技术安全措施基本能实现锂电池安全船用的预期目标。

关键词：纯电池动力锂电池低电压穿越直流综合电力系统