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Contrast in vulnerability to freezing-induced xylem embolism contributes to divergence in spring phenology between diffuse-and ring-porous temperate trees

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Forest Ecosystems 2022年第6期9卷 734-744页

作者： Ai-Ying Wang Han-Xiao Cui xue-wei gong Jing-Jing Guo Nan Wu Guang-You Hao School of Life Sciences and Engineering Shenyang UniversityShenyang110044LiaoningChina Liaoning Key Laboratory of Urban Integrated Pest Management and Ecological Security College of Life Science and BioengineeringShenyang UniversityShenyang110044LiaoningChina CAS Key Laboratory of Forest Ecology and Management Institute of Applied EcologyChinese Academy of SciencesShenyang110016China University of Chinese Academy of Sciences Beijing100049China Tree Laboratory Shenyang Academy of Landscape-gardeningShenyang110016LiaoningChina

Background:The spring phenology and growth strategy of temperate tree species can be strongly linked to their sensitivity to frosts,which deserve more profound investigations under the background of climate warming particularly considering the advancement of spring phenology as well as the increase in frequency and intensity of spring cold ***:Spring phenologies,stem radial growth characteristics,frost sensitivity of leaves and stem hydraulic systems were studied in five diffuse-porous and five ring-porous temperate tree species under a common garden ***:The results showed that the spring leaf phenology of the diffuse-porous species was one to two weeks earlier than that of the ring-porous *** ring-porous species had significantly higher stem hydraulic conductivity than the diffuse-porous species(1.81 and 0.95 kg·m^(-1)·s^(-1)·MPa^(-1),P<0.05)but were more vulnerable to freeze-thaw induced xylem embolism than the *** a simulated freeze-thaw event,the average percentage loss of hydraulic conductivity in the current year shoots increased from 26.0%(native embolism)to 86.7%in the ring-porous species,while it only increased from 21.3%to 38.3%in the diffuse-porous *** spring phenology was clearly correlated with vulnerability to freeze-thaw induced embolism,with the more vulnerable ring-porous species exhibited substantially delayed phenology to reduce risks of catastrophic hydraulic dysfunction during spring ***,ring-porous species can offset the postponed onset of growth and gained even higher annual growth due to significantly higher hydraulic efficiency and leaf gas exchange ***:Contrasts between ring-porous and diffuse-porous species in resistance to freeze-thaw induced embolism suggest that they face different selective pressures from early spring frosts,which may at least be partially responsible for their divergence in spring phenology and growth strategy and can potentially lead to di

关键词： Diffuse-porous trees Freeze-thaw cycle Frost damage Ring-porous trees Spring phenology Xylem embolism

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Change of hs-CRP,sVCAM-1,NT-proBNP levels in patients with pregnancy-induced hypertension after therapy with magnesium sulfate and nifudipine

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Asian Pacific Journal of Tropical Medicine 2013年第11期6卷 897-901页

作者： Li Wang Zhi-Qiang Liu Ying-Qian Huo Li-Juan Yao xue-gong wei Yun-Fang Wang Affiliated Hospital of Binzhou Medical College

Objective:To investigate the change of the hs-CRP,sVC AM-1,NT-proBNP levels of the patients with pregnancy-induced hypertension(PIH) ***:A total of 200 patients with PIH were divided into mild,moderate and severe group,and 50 healthy pregnancy patients served as the control *** serum sVCAM-1 levels were detected by enzyme-linked immunosorbent assay,hs-CRP were detected by immunity transmission turbidity,and NT-proBNP levels were determined by the colloidal gold *** were treated with magnesium sulfate and nifudipine and the contrastive analysis was performed before and after *** the pathological changes in placental of PIH patients were delected by hematoxylin-eosin staining at the same ***:The hs-CRP,sVCAM-l,NT-proBNP levels of patients in the mild, moderate and severe PHI group were significantly higher than that in the control group(P<0.05). The hs-CKP,sVCAM-l,NT-proBNP levels in the severe group were significantly higher than the mild group and the moderate group,the difference was statistically significant(P<0.05).The hsCRP,sVCAM-l,NT-proBNP of the moderate group were significantly higher than the mild group(P<0.05).There was a positive correlation between hs-CRP,sVCAM-1,NT-proBNP expression levels and the degree of the *** expression of hs-CRP,sVCAM-1,NT-proBNP levels of the moderate and the severe group were significantly decreased(P<0.05).The number of placental villi and interstitial blood vessel in the moderate and severe PIH group were significantly less than the control group(P<0.05).Conclusions:The increased levels of serum hs-CRP,sVCAM-1, NT-proBNP may be involved in the process of vascular endothelial cell injury of the PIH,and the hs-CRP,sVCAM-1,NT-proBNP can be used as the auxiliary index for diagnosis of PIH and determination of PIH severity.

关键词： Pregnancy-induced hypertension Soluble vascular cell adhesion molecule-1 Ultra-sensitivity C-reactive protein Amino-terminal pro-brain natriuretic peptide

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细胞自噬与非小细胞肺癌的研究进展

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生命科学 2019年第2期31卷 195-200页

作者：何艳郑立敏龚雪巍盛德乔三峡大学医学院肿瘤微环境与免疫治疗湖北省重点实验室宜昌443002

自噬不仅与NSCLC的增殖、侵袭及转移密切相关,而且在抗肿瘤药物介导的细胞死亡中发挥重要作用,因此,研发以自噬为靶点的药物可能是人类疾病治疗应用的新趋势。多种信号通路参与了细胞自噬的调控,明确细胞自噬的调控机制能为NSCLC的靶向... 详细信息

自噬不仅与NSCLC的增殖、侵袭及转移密切相关,而且在抗肿瘤药物介导的细胞死亡中发挥重要作用,因此,研发以自噬为靶点的药物可能是人类疾病治疗应用的新趋势。多种信号通路参与了细胞自噬的调控,明确细胞自噬的调控机制能为NSCLC的靶向治疗提供新思路。

关键词：自噬 NSCLC 自噬相关基因 mTOR 治疗

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Correlation analyse between thyroid hormone levels and severity of schizophrenia symptoms

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World Journal of Psychiatry 2025年第1期15卷 63-71页

作者： Qi-Hui Jiang wei-Dong gong Department of Endocrinology and Metabolism Hengyang Central HospitalHengyang 421000Hunan ProvinceChina Breast Tumor Surgical Outpatient Hengyang Central HospitalHengyang 421000Hunan ProvinceChina

BACKGROUND The imbalance of hormone levels in the body is closely related to the occurrence and progression of schizophrenia,especially thyroid *** To study the relationship between triiodothyronine(T3),thyroxine(T4),free T3(FT3),free T4(FT4),thyroid stimulating hormone(TSH)and *** In this study,100 schizophrenia patients were selected from our hospital between April 2022 and April *** clinical data were analyzed *** on the Positive and Negative Syndrome Scale(PANSS)score,patients were divided into mild(1-3 points,n=39),moderate(4 points,n=45),and severe groups(5-7 points,n=16).Additionally,55 healthy individuals served as a control *** blood samples were collected to measure T3,T4,FT3,FT4,TSH,and cortisol concentrations,analyzing their relationship with PANSS *** The serum levels of T3,FT3,FT4,TSH and cortisol in the schizophrenia group were lower than those in the control group(P<0.05).With the increase of the severity of the disease,the concentrations of T3 and T4 decreased,while the con-centrations of TSH and cortisol increased(P<0.05).The concentrations of TSH and cortisol were positively correlated with the PANSS score,while T3 and T4 were negatively correlated with the PANSS score(P<0.05).The receiver ope-rating characteristic curve results showed that T3,T4,TSH,and cortisol had good efficacy in the diagnosis of *** results showed that decreased T3 level,decreased T4 level,decreased TSH level and increased cortisol level may be independent risk factors for *** Thyroid hormone levels are associated with the severity of schizophrenia symptoms,which can provide new solutions for the diagnosis and treatment of schizophrenia.

关键词： Thyroid hormone Schizophrenia Symptom severity Positive and Negative Syndrome Scale score Cortisol

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微小RNA-29与恶性肿瘤

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生命科学 2017年第6期29卷 600-605页

作者：郑立敏龚雪巍盛德乔三峡大学医学院肿瘤微环境与免疫治疗湖北省重点实验室宜昌443002

miR-29家族是人类重要的miRNA分子,在多数恶性肿瘤中扮演抑癌RNA分子的作用,因而呈现低表达水平,它通过上调抑癌基因表达及调控相关肿瘤信号通路等机制,抑制恶性肿瘤的增殖、分化、侵袭和转移。miR-29家族不仅能作为恶性肿瘤治疗的靶点... 详细信息

miR-29家族是人类重要的miRNA分子,在多数恶性肿瘤中扮演抑癌RNA分子的作用,因而呈现低表达水平,它通过上调抑癌基因表达及调控相关肿瘤信号通路等机制,抑制恶性肿瘤的增殖、分化、侵袭和转移。miR-29家族不仅能作为恶性肿瘤治疗的靶点,而且在肿瘤的诊断及预后评估方面具有重要价值。

关键词： miR-29 恶性肿瘤诊断治疗预后

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狭果鹤虱幼苗营养生长和生物量分配对凝结水梯度的响应

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应用生态学报 2016年第7期27卷 2257-2263页

作者：龚雪伟吕光辉冉启洋杨晓东新疆大学资源与环境科学学院乌鲁木齐830046 绿洲生态教育部重点实验室乌鲁木齐830046 新疆大学干旱生态环境研究所乌鲁木齐830046

以新疆艾比湖湿地国家级自然保护区荒漠短命植物狭果鹤虱为研究对象,研究少凝结水、自然凝结水和倍增凝结水3个梯度下狭果鹤虱幼苗形态、生理响应对策及单株植物的干物质分配格局.结果表明:随凝结水量增加,狭果鹤虱幼苗与叶片吸收水分... 详细信息

以新疆艾比湖湿地国家级自然保护区荒漠短命植物狭果鹤虱为研究对象,研究少凝结水、自然凝结水和倍增凝结水3个梯度下狭果鹤虱幼苗形态、生理响应对策及单株植物的干物质分配格局.结果表明:随凝结水量增加,狭果鹤虱幼苗与叶片吸收水分有关的性状叶绿素相对含量、叶片水势、株高、冠幅、茎质量和叶质比均显著增高,而与根吸收和运输水分有关的性状主茎径、根长和根径无显著变化;株高和叶绿素相对含量对凝结水量的响应最迅速;不同凝结水梯度下,狭果鹤虱幼苗对茎的生物量投入比例无显著差异,但随幼苗生长,3个梯度植物的根质比均逐渐下降,少凝结水处理植株降幅相对较小.狭果鹤虱幼苗主要通过改变地上部分性状响应凝结水量的变化,叶片光合潜力和干物质比重随凝结水量增加而显著增加.

关键词：短命植物光合潜力荒漠

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基于光子晶体腔链的量子态传输及相位门的实现

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量子光学学报 2018年第1期24卷 30-38页

作者：范明营周凤雪林功伟钮月萍龚尚庆华东理工大学理学院

研究了光子晶体腔链中任意两奇数节点间量子态传输及相位门实现的问题。发现在绝热条件下,通过求解原子和光子晶体腔链耦合模型的暗态,可实现一维光子晶体耦合腔链中两个腔之间二维量子态的传输及可控相位门。在量子态传输的过程中若原... 详细信息

研究了光子晶体腔链中任意两奇数节点间量子态传输及相位门实现的问题。发现在绝热条件下,通过求解原子和光子晶体腔链耦合模型的暗态,可实现一维光子晶体耦合腔链中两个腔之间二维量子态的传输及可控相位门。在量子态传输的过程中若原子与腔的耦合强度足够大,腔的激发态的布居数小到可以被忽略。最后讨论了腔链的长度与相位门保真度的关系以及腔链的长度、初态的制备、腔的衰减、原子与腔的耦合强度对量子态传输保真度的影响。

关键词：光子晶体腔链量子态传输暗态相位门

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miR-21在非小细胞肺癌中的研究进展

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生命科学 2018年第7期30卷 765-770页

作者：龚雪巍郑立敏盛德乔张利华三峡大学医学院肿瘤微环境与免疫治疗湖北省重点实验室宜昌443002 三峡大学第二人民医院儿科宜昌443000

肺癌是我国最常见的恶性肿瘤,发病率高且预后差。mi R-21可通过转录后调控机制调节多种与细胞增殖、血管生成和侵袭迁移相关的肿瘤抑制因子的表达,在肿瘤的发生发展及转移中发挥重要作用。mi R-21在非小细胞肺癌中高表达,与非小细胞肺... 详细信息

肺癌是我国最常见的恶性肿瘤,发病率高且预后差。mi R-21可通过转录后调控机制调节多种与细胞增殖、血管生成和侵袭迁移相关的肿瘤抑制因子的表达,在肿瘤的发生发展及转移中发挥重要作用。mi R-21在非小细胞肺癌中高表达,与非小细胞肺癌细胞增殖、血管生成、侵袭和转移密切相关,是一个潜在的肺癌诊断与转移的分子靶标。

关键词： mi R-21 非小细胞肺癌增殖血管生成侵袭和转移

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The interaction between KIF21A and KANK1 regulates dendritic morphology and synapse plasticity in neurons

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Neural Regeneration Research 2025年第1期20卷 209-223页

作者： Shi-Yan Sun Lingyun Nie Jing Zhang xue Fang Hongmei Luo Chuanhai Fu Zhiyi wei Ai-Hui Tang Hefei National Research Center for Physical Sciences at the Microscale CAS Key Laboratory of Brain Function and DiseaseMinistry of Education Key Laboratory for Membrane-less Organelles and Cellular DynamicsDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui ProvinceChina Institute of Artificial Intelligence Hefei Comprehensive National Science CenterHefeiAnhui ProvinceChina CAS Center for Excellence in Molecular Cell Sciences Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui ProvinceChina Department of Neurobiology School of Life SciencesSouthern University of Science and TechnologyShenzhenGuangdong ProvinceChina Brain Research Center Southern University of Science and TechnologyShenzhenGuangdong ProvinceChina

Morphological alterations in dendritic spines have been linked to changes in functional communication between neurons that affect learning and ***-4 KIF21A helps organize the microtubule-actin network at the cell cortex by interacting with KANK1;however,whether KIF21A modulates dendritic structure and function in neurons remains *** this study,we found that KIF21A was distributed in a subset of dendritic spines,and that these KIF21A-positive spines were larger and more structurally plastic than KIF21A-negative ***,the interaction between KIF21A and KANK1 was found to be critical for dendritic spine morphogenesis and synaptic *** of either KIF21A or KANK1 inhibited dendritic spine morphogenesis and dendritic branching,and these deficits were fully rescued by coexpressing full-length KIF21A or KANK1,but not by proteins with mutations disrupting direct binding between KIF21A and KANK1 or binding between KANK1 and *** down KIF21A in the hippocampus of rats inhibited the amplitudes of long-term potentiation induced by high-frequency stimulation and negatively impacted the animals’cognitive *** together,our findings demonstrate the function of KIF21A in modulating spine morphology and provide insight into its role in synaptic function.

关键词： actin cytoskeleton dendrite KANK1 KIF21A microtubule spine morphology spine synaptic plasticity talin1

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芝麻饼粕中蛋白质的提取及其应用研究现状

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食品研究与开发 2018年第14期39卷 220-224页

作者：文芬张淼邵雪梅龚倩魏陈四川旅游学院食品学院四川成都610100

芝麻饼粕是芝麻榨取油后的副产品,常作为饲料或肥料,芝麻蛋白是从芝麻饼粕中提取的一种新的营养植物蛋白,营养性和加工性能较高。介绍芝麻饼粕的制备方法、芝麻蛋白的提取方法、干燥方式和功能特性及其在食品中的应用状况,并对芝麻蛋白... 详细信息

芝麻饼粕是芝麻榨取油后的副产品,常作为饲料或肥料,芝麻蛋白是从芝麻饼粕中提取的一种新的营养植物蛋白,营养性和加工性能较高。介绍芝麻饼粕的制备方法、芝麻蛋白的提取方法、干燥方式和功能特性及其在食品中的应用状况,并对芝麻蛋白的研究前景做出展望。

关键词：芝麻饼粕芝麻蛋白提取方法干燥方式功能特性

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