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Drug-coated balloon angioplasty for the treatment of intracranial arterial stenosis in a young stroke patient:A case report

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World Journal of Clinical Cases 2024年第19期12卷 3956-3960页

作者： Peng-Cheng Zhu Ling-feng Shu Qing-Hai Dai Hong-Tu Tan Jia-Bin wang Tao Wu Department of Intervention Encephalopathy CenterThe First Affiliated Hospital of Henan University of Chinese MedicineZhengzhou 450000Henan ProvinceChina The First Clinical Medical College Henan University of Traditional Chinese MedicineZhengzhou 450046Henan ProvinceChina

BACKGROUND Intracranial arterial narrowing is a significant factor leading to brief episodes of reduced blood flow to the brain,known as transient ischemic attacks,or fullblown *** atherosclerosis is commonly associated with intracranial arterial narrowing,it is frequently of a non-atherosclerotic nature in younger *** SUMMARY Here,we present the case of a young stroke patient with narrowing of the middle cerebral artery(MCA),characterized as non-atherosclerotic lesions,who experienced an ischemic stroke despite receiving standard drug *** patient underwent digital subtraction angiography(DSA)to assess the entire network of blood vessels in the brain,revealing significant narrowing(approximately 80%)in the M1 segment of the right ***,the patient underwent Drug-Coated Balloon Angioplasty to treat the stenosis in the right MCA's M1 ***-up DSA confirmed the resolution of stenosis in this *** the remaining branches showed satisfactory blood flow,the vessel wall exhibited irregularities.A review of DSA conducted six months later showed no evident stenosis in the right MCA,with a smooth vessel *** The use of drug-coated balloon angioplasty demonstrated favorable outcomes in repairing and reshaping the blood vessel wall in young ***,it may be considered a promising treatment option for similar cases.

关键词： Intracranial arterial stenosis Middle cerebral artery Drug-coated balloon Young stroke Case report

TiO_(2) nanofiber-supported copper nanoparticle catalysts for highly efficient methane conversion to C1 oxygenates under mild conditions

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Nano Research 2024年第5期17卷 3844-3852页

作者： Wencui Li Yu Ren Zean Xie Yipeng wang Hang Zhang Dianxiang Peng Hengfang Shen Hongfei Shi Jiaxin Cai Peng wang Tongxin Zhang Zhen Zhao State Key Laboratory of Heavy Oil Processing China University of Petroleum(Beijing)Beijing 102249China Institute of Catalysis for Energy and Environment College of Chemistry&Chemical EngineeringShenyang Normal UniversityShenyang 110034China Institute of Petrochemical Technology Jilin Institute of Chemical TechnologyJilin 132022China

The selective oxidation of methane under mild conditions remains the“Holy Grail of Catalysis”.The key to activating methane and inhibiting over-oxidation of target oxygenates lies in designing active *** nanoparticles were loaded onto TiO_(2) nanofibers using the photo-deposition *** resulting catalysts were found to effectively convert methane into C1 oxygenated products under mild *** with previously reported catalysts,it delivers a superior performance of up to 2510.7 mmol·g_(Cu)^(-1)·h^(-1) productivity with a selectivity of around 100%at 80℃for 5 *** characterizations and density functional theory(DFT)calculations indicate that TiO_(2) in the mixed phase of anatase and rutile significantly increases the Cu^(+)/CuO ratio of the supported Cu species,and this ratio is linearly related to the formation rate of oxygen-containing *** CuI site promotes the generation of active O species from H_(2)O_(2) dissociation on Cu_(2)O(111).These active O species reduce the energy barrier for breaking the C-H bond of CH_(4),thus boosting the catalytic *** methane conversion mechanism was proposed as a methyl radical pathway to form CH_(3)OH and CH_(3)OOH,and then the generated CH_(3)OH is further oxidized to HOCH_(2)OOH.

关键词： TiO_(2)nanofiber copper nanoparticles photo-deposition method methane oxidation C1 oxygenates

Variations in the Prevalence of Anemia of Varying Severity Among Urban Non-Pregnant Women—China,2021

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China CDC weekly 2024年第10期6卷 175-180页

作者： Xiaoxi Liu Bo wang Sailimai Man Heling Bao Yuanyuan Huang Canqing Yu Jun Lyu Linhong wang Liming Li Hui Liu Institute of Medical Information Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijingChina Peking University Health Science Center Meinian Public Health Institute BeijingChina Meinian Institute of Health BeijingChina Peking University Center for Public Health and Epidemic Preparedness&Response BeijingChina Department of Epidemiology and Biostatistics School of Public HealthPeking UniversityBeijingChina Key Laboratory of Epidemiology of Major Diseases(Peking University) Ministry of EducationBeijingChina National Center for Chronic and Non-communicable Disease Control and Prevention Chinese Center for Disease Control and PreventionBeijingChina

Summary What is already known about this topic?Anemia is a significant public health issue affecting women *** studies in China predominantly concentrated on anemia in pregnant or reproductiveage women,leaving a gap i... 详细信息

关键词： Anemia anemia China.

Green development and economic resilience:Evidence from Chinese resource-based cities

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Frontiers of Engineering Management 2024年第2期11卷 194-206页

作者： Zongrun wang Xuxin CAO Xiaohang REN School of Business Central South UniversityChangsha 410083China

Resource-based cities are currently facing challenges due to ecological pollution and an unbalanced industrial structure,which hinders sustainable economic *** focus on green development as a strategy for economic growth and environmental protection is becoming increasingly *** study employs a spatial econometric model to explore the effect of green development on economic resilience in Chinese resource-based cities from 2011 to 2019,revealing a positive correlation between green development and economic *** each 1 unit increase in green development,economic resilience increases by an average of 0.512 ***,the analysis of heterogeneity reveals differences in the factors influencing various resource-based *** addition,provincial green policies bolster economic resilience by encouraging green *** research aids in comprehending the balance between the economy and the environment.

关键词： economic resilience green development spatial econometric models resource-based cities

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细胞焦亡及其在口腔疾病中的作用

中国生物化学与分子生物学报 2024年第9期40卷 1230-1239页

作者：王正森薛钰陈艺璇闽南师范大学菌物产业福建省高校工程研究中心

口腔疾病是指口腔在外界理化因子的损害、病原的侵入、牙颌面发育异常以及全身性疾病等情况下出现的病理现象，其引起的口腔感染及疼痛不适感严重降低患者的生存质量。细胞焦亡是一种细胞程序性死亡，其特征是细胞肿胀直至细胞膜破裂，... 详细信息

口腔疾病是指口腔在外界理化因子的损害、病原的侵入、牙颌面发育异常以及全身性疾病等情况下出现的病理现象，其引起的口腔感染及疼痛不适感严重降低患者的生存质量。细胞焦亡是一种细胞程序性死亡，其特征是细胞肿胀直至细胞膜破裂，细胞内容物释放并激活强烈的炎症反应。研究表明，细胞焦亡广泛参与调节口腔疾病的发生发展过程。本文详细介绍了4种类型的细胞焦亡途径，包括经典焦亡路径、非经典焦亡途径、胱天蛋白酶3/8介导的焦亡途径及不依赖胱天蛋白酶的焦亡途径。不同的焦亡途径形成复杂的信号网络，调控口腔中牙周膜细胞、牙龈成纤维细胞、巨噬细胞等多种细胞的生命活动，进而影响口腔疾病的发生与发展进程。该综述通过对大量文献信息的整合，对不同的细胞焦亡途径及其在口腔疾病中的作用进行了详细的梳理，旨在为寻找有效的治疗和预防口腔疾病的方法提供理论依据和研究方向。

关键词：焦亡炎症小体炎症口腔疾病

Coupled single-cell and bulk RNA-seq analysis reveals the engulfment role of endothelial cells in atherosclerosis

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Genes & Diseases 2024年第5期11卷 442-455页

作者： Jianxiong Xu Jinxuan wang Hongping Zhang Yidan Chen Xiaojuan Zhang Ying Zhang Ming Xie Jun Xiao Juhui Qiu Guixue wang Key Laboratory for Biorheological Science and Technology of Ministry of Education State and Local Joint Engineering Laboratory for Vascular ImplantsBioengineering Modern Life Science Experiment Teaching Center of Bioengineering CollegeChongqing UniversityChongqing 400030China Jinfeng Laboratory Chongqing 401329China School of Basic Medical Sciences Chengdu Medical CollegeChengduSichuan 610500China Chongqing Emergency Medical Center(Chongqing University Central Hospital) Chongqing 400014China

The clearance of apoptotic cell debris,containing professional phagocytosis and non-professional phagocytosis,is essential for maintaining the homeostasis of healthy ***,we discovered that endothelial cells could engulf apoptotic cell debris in atherosclerotic ***-cell RNA sequencing(RNA-seq)has revealed a unique endothelial cell subpopulation in atherosclerosis,which was strongly associated with vascular injury-related ***,integrated analysis of three vascular injury-related RNA-seq datasets showed that the expression of scavenger receptor class B type 1(SR-B1)was up-regulated and specifically enriched in the phagocytosis pathway under vascular injury ***-cell RNA-seq and bulk RNA-seq indicate that SR-B1 was highly expressed in a unique endothelial cell subpopulation of mouse aorta and strongly associated with the reorganization of cellular adherent junctions and cytoskeleton which were necessary for ***,SR-B1 was strongly required for endothelial cells to engulf apoptotic cell debris in atherosclerotic plaque of both mouse and human ***,this study demonstrated that apoptotic cell debris could be engulfed by endothelial cells through SR-B1 and associated with the reorganization of cellular adherent junctions and cytoskeleton.

关键词： Apoptotic cell debris Atherosclerosis Endothelial engulfment Single-cell RNA sequencing Scavenger receptor class B type 1

New Strategy for Boosting Cathodic Performance of Protonic Ceramic Fuel Cells Through Incorporating a Superior Hydronation Second Phase

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Energy & Environmental Materials 2024年第4期7卷 83-92页

作者： Chuan Zhou Xixi wang Dongliang Liu Meijuan Fei Jie Dai Daqin Guan Zhiwei Hu Linjuan Zhang Yu wang Wei wang Ryan O'Hayre San Ping Jiang Wei Zhou Meilin Liu Zongping Shao State Key Laboratory of Materials-Oriented Chemical Engineering College of Chemical Engineering Nanjing Tech University Max Planck Institute for Chemical Physics of Solids Key Laboratory of Interfacial Physics and Technology Shanghai Institute of Applied Physics Chinese Academy of Sciences Department of Metallurgical and Materials Engineering Colorado School of Mines WA School of Mines: Minerals Energy and Chemical Engineering (WASM-MECE) Curtin University Suzhou Laboratory School of Materials Science and Engineering Georgia Institute of Technology

For protonic ceramic fuel cells,it is key to develop material with high intrinsic activity for oxygen activation and bulk proton conductivity enabling water formation at entire electrode ***,a higher water content which benefitting for the increasing proton conductivity will not only dilute the oxygen in the gas,but also suppress the O2adsorption on the electrode surface.

关键词： cathode high-hydrating capability proton conductivity protonic ceramic fuel cells

Improving access to urban parks through public transit optimization

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Frontiers of Architectural Research 2024年第3期13卷 575-592页

作者： Ning Xu Kaidan Guan Pu wang School of Architecture Southeast UniversityNanjing 210096China Jiangsu Provincial Urban and Rural Digital Technology Engineering Center Nanjing 210096China

This study establishes an evaluation and optimization framework for the public transit network based on social network analysis and a greedy algorithm,aiming to explore a quantitative approach to improving access to urban parks through public transit *** network analysis and the ArcGIS platform are used to build a public transit network model within Nanjing Old City and analyze its overall network structure *** study also focuses on a method to improve the convenience of reaching regional and citylevel parks by public transit by increasing access and connecting points accordingly.A greedy algorithm is introduced to generate an optimized solution for improving public transit accessibility to regional and city-level parks,consequently enhancing their *** major findings include:(1)The greedy algorithm effectively enhances the performance of the public transit network,but its benefits gradually diminish as more stations are added.(2)Strategically adding stations enhances the performance of most public transit access points,creating efficient pathways for other stations to directly reach these access points and enter regional and city-level parks.(3)The optimized public transit network model offers guidance for the planning and layout of regional and city-level *** site selection for new parks should prioritize establishing connections with the“hubs”in the public transit *** proposed optimization of the public transit network in this study is specific to a single type of urban park,but subsequent research could be conducted to extend the optimization of public transit accessibility around more urban public resources.

关键词： Urban parks Social network analysis Accessibility optimization Public transit network Greedy algorithm

Hydrocarbon gas huff-n-puff optimization of multiple horizontal wells with complex fracture networks in the M unconventional reservoir

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Petroleum Science 2024年第2期21卷 1018-1031页

作者： Hao-Chuan Zhang Yong Tang You-Wei He Yong Qin Jian-Hong Luo Yu Sun Ning wang De-Qiang wang State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Southwest Petroleum UniversityChengdu610500SichuanChina CNPC Research Institute of Petroleum Exploration&Development Beijing100083China Southwest Oil&Gas Field Company PetroChinaChengdu610051SichuanChina State Key Laboratory of Offshore Oil Exploitation CNOOC Research Institute Co.LtdBeijing100027China

The oil production of the multi-fractured horizontal wells(MFHWs) declines quickly in unconventional oil reservoirs due to the fast depletion of natural energy. Gas injection has been acknowledged as an effective method to improve oil recovery factor from unconventional oil reservoirs. Hydrocarbon gas huff-n-puff becomes preferable when the CO_(2) source is limited. However, the impact of complex fracture networks and well interference on the EOR performance of multiple MFHWs is still unclear. The optimal gas huff-n-puff parameters are significant for enhancing oil recovery. This work aims to optimize the hydrocarbon gas injection and production parameters for multiple MFHWs with complex fracture networks in unconventional oil reservoirs. Firstly, the numerical model based on unstructured grids is developed to characterize the complex fracture networks and capture the dynamic fracture ***, the PVT phase behavior simulation was carried out to provide the fluid model for numerical simulation. Thirdly, the optimal parameters for hydrocarbon gas huff-n-puff were obtained. Finally, the dominant factors of hydrocarbon gas huff-n-puff under complex fracture networks are obtained by fuzzy mathematical method. Results reveal that the current pressure of hydrocarbon gas injection can achieve miscible displacement. The optimal injection and production parameters are obtained by single-factor analysis to analyze the effect of individual parameter. Gas injection time is the dominant factor of hydrocarbon gas huff-n-puff in unconventional oil reservoirs with complex fracture networks. This work can offer engineers guidance for hydrocarbon gas huff-n-puff of multiple MFHWs considering the complex fracture networks.

关键词： Unconventional oil reservoir Complex fracture network Hydrocarbon gas huff-n-puff Parameter optimization Numerical simulation