检索结果-南通市图书馆

The Finite-time Ruin Probability of a Discrete-time Risk Model with Subexponential and Dependent Insurance and Financial Risks

在线全文

学校读者我要写书评

暂无评论

Acta Mathematicae Applicatae Sinica 2018年第3期34卷 553-565页

作者： Shi-jie wang Chuan-wei ZHANG xue-jun wang Wen-sheng wang School of Mathematic Sciences Anhui University Hefei 230601 China School of Economics Hangzhou Dianzi University Hangzhou 310018 China

Consider a discrete-time risk model with insurance and financial risks in a stochastic economic environment. Assume that the insurance and financial risks form a sequence of independent and identically distributed random vectors with a generic random vector following a wide type of dependence structure. An asymptotic formula for the finite-time ruin probability with subexponential insurance risks is derived. In doing so, the subexponentiality of the product of two dependent random variables is investigated simultaneously.

关键词： discrete-time risk model finite-time ruin probability subexponentiality product dependence structure

Hajek-Rényi-type Inequality and Strong Law of Large Numbers for Some Dependent Sequences

在线全文

学校读者我要写书评

暂无评论

Acta Mathematicae Applicatae Sinica 2012年第3期28卷 495-504页

作者： Wen-zhi YANG Yan SHEN Shu-he HU xue-jun wang School of Mathematical Science Anhui UniversityHefei 230039China

Abstract In this paper, we get the H^jek-R^nyi-type inequalities for a pairwise NQD sequence, an L^T （r 〉 1） mixingale and a linear process, which have the concrete coefficients. In addition, we obtain the strong law of large numbers, strong growth rate and the integrability of supremum for the above sequences, which generalize and improve Corollary 2 for L^T（r 〉 1） mixingale of Hansen.

关键词： Hajek-Renyi-type inequality pairwise NQD sequence L^r(r 〉 1) mixingale linear process

Almost Sure Convergence Theorem and Strong Stability for Weighted Sums of NSD Random Variables

在线全文

学校读者我要写书评

暂无评论

Acta Mathematica Sinica,English Series 2013年第4期29卷 743-756页

作者： Yan SHEN xue jun wang Wen Zhi YANG Shu He HU School of Mathematical Science Anhui University

In this paper, Kolmogorov-type inequality for negatively superadditive dependent （NSD） random variables is established. By using this inequality, we obtain the almost sure convergence for NSD sequences, which extends the corresponding results for independent sequences and negatively associated （NA） sequences. In addition, the strong stability for weighted sums of NSD random variables is studied.

关键词： Almost sure convergence negatively superadditive dependent strong stability

RNA-binding protein CPSF6 regulates IBSP to affect pyroptosis in gastric cancer

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2023年第9期15卷 1531-1543页

作者： xue-jun wang Yong Liu Bin Ke Li Zhang Han Liang Department of Gastric Oncology Tianjin Medical University Cancer Institute and HospitalNational Clinical Research Center for CancerTianjin’s Clinical Research Center for CancerTianjin Key Laboratory of Digestive CancerTianjin 300060China

BACKGROUND Extensive evidence has illustrated the promotive role of integrin binding sialoprotein(IBSP)in the progression of multiple ***,little is known about the functions of IBSP in gastric cancer(GC)*** To investigate the mechanism underlying the regulatory effects of IBSP in GC progression,and the relationship between IBSP and cleavage and polyadenylation factor 6(CPSF6)in this *** The mRNA and protein expression of relevant genes were assessed through realtime quantitative polymerase chain reaction and Western blot,*** viability was evaluated by Cell Counting Kit-8 *** invasion and migration were evaluated by Transwell *** was measured by flow *** binding between CPSF6 and IBSP was confirmed by luciferase reporter and RNA immunoprecipitation(RIP)*** IBSP exhibited higher expression in GC tissues and cell lines than in normal tissues and cell *** knockdown suppressed cell proliferation,migration,and invasion but facilitated *** the exploration of the regulatory mechanism of IBSP,potential RNA binding proteins for IBSP were screened with catRAPID omics *** RNA-binding protein CPSF6 was selected due to its higher expression in stomach *** reporter and RIP assays revealed that CPSF6 binds to the 3’-untranslated region of IBSP and regulates its *** of CPSF6 inhibited cell proliferation,migration,and invasion but boosted *** rescue assays,it was uncovered that the retarded GC progression mediated by CPSF6 knockdown was reversed by IBSP *** Our study highlighted the vital role of the CPSF6/IBSP axis in GC,suggesting that IBSP might be an effective biotarget for GC treatment.

关键词： Integrin binding sialoprotein Cleavage and polyadenylation factor 6 Pyroptosis Gastric cancer

A novel synthesized prodrug of gemcitabine based on oxygen-free radical sensitivity inhibited the growth of lung cancer cells

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

生物医学研究杂志:英文版 2023年第5期37卷 355-366页

作者： Xinlu Chai Yuting Meng Wei Ge Juan wang Fei Li xue jun wang xuerong wang Department of Pharmacology Nanjing Medical UniversityNanjingJiangsu 210029China Department of Pharmacology Wannan Medical CollegeWuhuAnhui 241002China Department of Pharmacy Nanjing Medical UniversityNanjingJiangsu 210029China Department of Biochemistry and Molecular Biology Nanjing Medical UniversityNanjingJiangsu 210029China.

In the present study,we introduced the H2O2-sensitive thiazolidinone moiety at the 4th amino group of gemcitabine(GEM)to synthesize a new target compound named GEM-ZZQ,and then we confirmed its chemical structure by nuclear magnetic resonance *** further confirmed that GEM-ZZQ had a good chemical stability in different pH solutions in vitro and that it could be activated by H2O2 to release *** studies revealed that the growth inhibition of human normal epithelial cells was weaker by GEM-ZZQ than by GEM treatment and that the inhibition of various lung cancer cell lines by GEM-ZZQ was similar to that of *** the lung cancer cell lines that are resistant to the epidermal growth factor receptor(EGFR)-targeting inhibitor osimertinib,GEM-ZZQ showed less growth inhibition than GEM;however,GEM-ZZQ in combination with cisplatin showed better synergistic effects than GEM in the low-dose *** summary,we provided a new anti-cancer compound GEM-ZZQ for treating lung cancer by modifying the GEM structure.

关键词： gemcitabine thiazolidinone H2O2-sensitive moiety non-small cell lung cancer

Characteristic Study of Self-Powered Sensors Based on Native Protein Composite Film

在线全文

学校读者我要写书评

暂无评论

Energy & Environmental Materials 2024年第1期7卷 222-228页

作者： Jiehui xue Huijing Xiang Yanrong Zhang jun Yang Xia Cao Zhonglin wang Beijing Institute of Nanoenergy and Nanosystems Chinese Academy of SciencesBeijing 101400China School of Resources Environment and MaterialsSchool of PhysicsScience and TechnologyCenter on Nanoenergy ResearchGuangxi UniversityNanning 530004China Center for Green Innovation School of Mathematics and PhysicsUniversity of Science and Technology BeijingBeijing 100083China Research Centre of Information Technology Shenzhen Institute of Information TechnologyShenzhen 518172China School of Chemistry and Biological Engineering University of Science and Technology BeijingBeijing 100083China School of Materials Science and Engineering Georgia Institute of TechnologyAtlanta GA 30332-0245USA

Flexible electronic sensors composed of flexible film and conductive materials play an increasingly important role in wearable and internet information *** has received more and more attention and made some progress over the ***,it is still a great challenge to prepare biocompatible and highly transparent conductive *** white is a pure natural protein-rich *** cellulose has a good compatibility and high transparency,which is an ideal material for flexible ***,we overcome the problem of poor mechanical flexibility and electrical conductivity of protein,and develop a high transparency and good flexibility hydroxypropylmethyl cellulose/egg white protein composite membrane-based triboelectric nanogenerator('X'-TENG).The experimental results show that the flexible pressure sensor based on'X'-TENG has a high sensitivity,fast response speed,and low detection *** can even be used as a touch/pressure sensing artificial electronic *** can also be made into an intelligent waffle keyboard for recording and tracking users of the *** strategy may provide a new way to easily build flexible electronic sensors and move toward practical applications.

关键词： flexible sensors intelligent sensing natural protein-rich material triboelectric nanogenerators

Unraveling role of double-exchange interaction in electrochemical water oxidation by external magnetic field

在线全文

学校读者我要写书评

暂无评论

Rare Metals 2024年第1期43卷 289-297页

作者： jun Li jun-Ming Li Hong Hong Dong-xue Liu Qing-Qi Cao Dun-Hui wang National Laboratory of Solid State Microstructures and Jiangsu Provincial Key Laboratory for Nanotechnology Nanjing UniversityNanjing 210093China School of Electronics and Information Hangzhou Dianzi UniversityHangzhou 310018China

Double-exchange(DE) interaction plays an important role in electrocatalytic oxygen evolution reaction(OER).However,precise achievement of DE interaction often requires foreign dopants or vacancy engineering,leading to destabilization of the catalysts and deterioration of *** contrast,the utilization of environmentally friendly,contactless,and continuously adjustable magnetic fields to study the OER process is profitable to avoid aforementioned interference factors and further elucidate the direct relationship_(0.5)between DE interaction and OER ***,by using cobalt hydroxide carbonate(Co(OH)(CO_(3))·xH_(2)O,CoHC) nanostructures as a proof-of-concept study,external magnetic fields are carefully implemented to verify the role of DE interaction during water oxidation *** studies reveal that external magnetic fields effectively enhance the reaction rate of the catalyst,the overpotential decreases from 386 to 355 mV(100 mA·cm^(-2)),while Tafel slopes drastically decline from 93 to 67 mV·dec^(-1)(1.0 T).Moreover,magnetic field increment exhibits robust *** in situ Raman and impedance measurements under external field,it can be found that magnetic field promotes the electron migration between Co^(2+) and Co^(3+) in the CoHC catalysts with the assistance of DE interactions,thus boosting the OER efficiency.

关键词： Magnetic field Double-exchange(DE)interaction Electrocatalysis Oxygen evolution reaction(OER) Cobalt hydroxide carbonate

The reservoir characteristics and their controlling factors of the sublacustrine fan in the Paleogene Dongying Formation, Bohai Sea,China

在线全文

学校读者我要写书评

暂无评论

Journal of Palaeogeography 2024年第1期13卷 127-148页

作者： Xiao-jun Pang Guan-Min wang Meng Zhao Qing-Bin wang xue-Fang Zhang School of Geosciences China University of Petroleum(East China)QingdaoShandong 266580China Tianjin Branch of China National Offshore Oil Corporation Limited Tianjin 300459China

Sublacustrine fan is an important element in continental lacustrine basins and is significant for reservoir exploration. Oil and gas resources have been found in the sublacustrine fan sandstone reservoirs of the Paleogene Dongying Formation in the Bohai Sea. In this study, the characteristics of the sublacustrine fan reservoirs and the controlling factors are studied using information from logging, cores, physical properties,casting thin sections, X-ray diffraction of clay minerals, vitrinite reflectance, rock pyrolysis, manometry data,and 3D seismic data. The sublacustrine fans of the Dongying Formation in the LD10, QHD34, and BZ21 structures show high-quality reservoirs with porosity >15 % and permeability >5 m D. The main controlling factors of the high-quality reservoirs are attributed to the favorable sedimentary facies type and negligible compaction,and cementation, substantial dissolution of K-feldspar, overpressure, and the development of faults and fractures. A high-quality sublacustrine fan reservoir model has been established to explain how these factors affected the physical properties. The favorable targets for oil and gas exploration in the Dongying Formation of Bohai Sea include undercompacted sandy debris flow reservoirs showing the dissolution of K-feldspar, and the reservoirs which are connected to the source rocks by faults. This study provides insights to establish the relationship between sedimentology, diagenesis and reservoir quality. The results of this study are significant for the exploration and development of the sublacustrine fan sandstone reservoirs in the Bohai Sea and analogous sandstone reservoirs elsewhere.

关键词： Sublacustrine fan High-quality reservoir Dissolution Overpressure Fault Bohai Sea

Evolution of pore systems in low-maturity oil shales during thermal upgrading--Quantified by dynamic SEM and machine learning

在线全文

学校读者我要写书评

暂无评论

Petroleum Science 2024年第3期21卷 1739-1750页

作者： jun Liu xue Bai Derek Elsworth Key Laboratory of Deep Underground Science and Engineering(Ministry of Education) Institute of New Energy and Low-Carbon TechnologySichuan UniversityChengdu610065SichuanChina International Quantum Academy Shenzhen518048GuangdongChina Shenzhen Institute of Advanced Electronic Materials Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen518055GuangdongChina Department of Energy and Mineral Engineering Pennsylvania State University ParkPA 16802USA

In-situ upgrading by heating is feasible for low-maturity shale oil,where the pore space dynamically *** characterize this response for a heated substrate concurrently imaged by *** systematically follow the evolution of pore quantity,size(length,width and cross-sectional area),orientation,shape(aspect ratio,roundness and solidity)and their anisotropy—interpreted by machine *** indicate that heating generates new pores in both organic matter and inorganic ***,the newly formed pores are smaller than the original pores and thus reduce average lengths and widths of the bedding-parallel pore ***,the average pore lengths and widths are increased in the bedding-perpendicular ***,heating increases the cross-sectional area of pores in low-maturity oil shales,where this growth tendency fluctuates at300℃.In addition,the orientation and shape of the newly-formed heating-induced pores follow the habit of the original pores and follow the initial probability distributions of pore orientation and ***,limited anisotropy is detected in pore direction and shape,indicating similar modes of evolution both bedding-parallel and *** propose a straightforward but robust model to describe evolution of pore system in low-maturity oil shales during heating.

关键词： Low-maturity oil shale Pore elongation Organic matter pyrolysis In-situthermal upgrading Scanning electron microscopy(SEM) Machine learning