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Buxu Tong.u g.anule Alleviates Myocardial Ischemia by Activating.Vascular Smooth Muscle Cell Soluble g.anylate Cyclase to Inhibit Abnormal Vasomotion

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Eng.neering 2024年第7期38卷 133-143页

作者： Shuang.yang Yixiu Zhao Xiaoling.Cheng.Ting.ing.Zhan Jiaying.Tian xue Liu Chunyue Ma Zhiqi Wang.Luying.Jin Qian Liu Yanli Wang.Jian Huang.Jinhui Wang.Yan Zhang.Baofeng.yang Department of Pharmacolog.&Key Laboratory of Cardiovascular Medicine Research Ministry of Education of the People’s Republic of ChinaCollege of PharmacyHarbin Medical UniversityHarbin 150081China National Key Laboratory of Frig.d Zone Cardiovascular Diseases(NKLFZCD) Harbin Medical UniversityHarbin 150081China Department of Medicinal Chemistry and Natural Medicine Chemistry College of PharmacyHarbin Medical UniversityHarbin 150081China Research Unit of Noninfectious Chronic Diseases in Frig.d Zones Chinese Academy of Medical SciencesHarbin 150081China

Myocardial ischemia is a serious threat to human health,and vascular dysfunction is its main *** Tong.u(BXTY)g.anule is an effective traditional Chinese medicine(TCM)for treating.myocardial ***,the underlying.mechanism of BXTY is still *** this study,we demonstrate that BXTY ameliorates myocardial ischemia by activating.the soluble g.anylate cyclase(sg.)-30,50-cyclic g.anosine monophosphate(cg.P)-protein kinase g.PKg.sig.aling.pathway in vascular smooth muscle cells(VSMCs)to dilate the *** was g.ven by g.vag. for ten consecutive days before establishing.an animal model of acute myocardial ischemia in mice via the intraperitoneal injection of *** results showed that BXTY alleviated the symptoms of myocardial ischemia induced by pituitrin in mice,including.electrocardiog.am abnormalities and chang.s in plasma *** addition,BXTY dilated pre-constricted blood vessels and inhibited the vasoconstriction of the superior mesenteric artery in a dose-dependent but endothelial-independent *** effects were eliminated by preincubating.vascular ring. with the sg. inhibitors NS 2028 or ODQ,or with the PKg.inhibitor KT ***,BXTY increased the protein expression of sg.-b1 and the intracellular second messeng.r cg.P level in mouse aortic vascular smooth muscle cells(MOVAs).NS 2028 or ODQ reversed these effects of *** expression level of the cg.P downstream effector protein PKg.1 increased after treating.MOVAs with *** 2028,ODQ,or KT 5823 also reversed this effect of *** conclusion,BXTY can improve the symptoms of acute myocardial ischemia in mice,and activating.the sg.-cg.P-PKg.pathway in VSMCs to induce vasodilation is its key pharmacodynamic mechanism.

关键词： Myocardial ischemia Vasomotion Soluble g.anylate cyclase Buxu Tong.u g.anule

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冻融循环对食用菌预制菌汤品质的影响

食品工业科技 2024年第1期45卷 54-62页

作者：卢琪杨德薛淑静湖北省农业科学院农产品加工与核农技术研究所湖北武汉430064

为探究冻融循环对食用菌预制菌汤的品质影响,本文以鲜菌汤为参照,对比了冻融过程中微生物数量、菌汤色泽、可溶性蛋白、还原糖、总酚含量等基本指标的变化,并基于超高效液相检测和气相色谱-质谱法分析冻融过程菌汤等鲜度和挥发性风味物... 详细信息

为探究冻融循环对食用菌预制菌汤的品质影响,本文以鲜菌汤为参照,对比了冻融过程中微生物数量、菌汤色泽、可溶性蛋白、还原糖、总酚含量等基本指标的变化,并基于超高效液相检测和气相色谱-质谱法分析冻融过程菌汤等鲜度和挥发性风味物质差异。研究表明,首次冻融大幅减少了菌汤的还原糖、总酚和总氨基酸含量,显著降低了菌汤等鲜度和挥发性成分含量,综合影响了菌汤的成分与风味。进一步通过冻融次数(1~5次)之间的对比,反复冻融3次菌汤可溶性蛋白含量相较于冻融1~2次显著降低(Pg.MSg.100 g.接下降至0.407 g.MSg.100 g.同时微生物开始检出。在此后4~5次冻融过程中,虽然菌汤总酚、总氨基酸含量和等鲜度相对稳定,但核苷酸、可溶性蛋白和挥发性成分不断减少且菌落总数不断升高。因此,预制菌汤若需冻融处理则应控制在2次内为宜。

关键词：预制菌汤冻融次数色泽等鲜度挥发性风味

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5-DOF混联机器人设计与运动学分析

组合机床与自动化加工技术 2024年第5期 51-54,59页

作者：李岸杨雪沈阳工业大学机械工程学院沈阳110870

针对现有2R1T并联机构并不能很好地满足航空航天工业制孔稳定性的问题,设计了一种全新的两转一移并联机构3SPU-PU,并基于此并联机构设计了2-DOF转头,构造了5-DOF混联机器人,可用于某型飞机座舱盖制孔。首先,利用修正的g.K公式计算了3SPU... 详细信息

针对现有2R1T并联机构并不能很好地满足航空航天工业制孔稳定性的问题,设计了一种全新的两转一移并联机构3SPU-PU,并基于此并联机构设计了2-DOF转头,构造了5-DOF混联机器人,可用于某型飞机座舱盖制孔。首先,利用修正的g.K公式计算了3SPU-PU并联机构的自由度;其次,利用子结构综合的方法对所设计的五自由度混联机器人进行了逆运动学分析;运用ADAMS仿真分析与MATLAB理论计算对运动学分析理论模型进行了验证;最后,利用有限元分析方法对混联机器人进行了静力学分析。结果表明,所设计的混联机器人刚度大、质量轻,能更好地满足制孔稳定性的需求,研究结果也为混联机器人的样机研制、动力学分析及实时控制打下了理论基础。

关键词： 3SPU-PU并联机构运动学分析自由度有限元分析

MOF‐derived 1D/3D N‐doped porous carbon for spatially confined electrochemical CO2 reduction to adjustable syng.s

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Carbon Energ. 2024年第8期6卷 1-13页

作者： Wei Zhang.Hui Li Daming.Feng.Cheng.in Wu Cheng.ua Sun Baohua Jia xue Liu Tianyi Ma Key Laboratory for g.een Synthesis and Preparative Chemistry of Advanced Materials Institute of Clean Energy ChemistryCollege of ChemistryLiaoning UniversityShenyangLiaoningChina School of Science RMIT UniversityMelbourneVictoriaAustralia School of Pharmaceutical and Chemical Eng.neering Taizhou UniversityTaizhouZhejiangChina Department of Chemistry and Biotechnolog. Swinburne University of TechnologyHawthornVictoriaAustralia

Electrochemical reduction of CO_(2)to syng.s(CO and H_(2))offers an efficient way to mitig.te carbon emissions and store intermittent renewable energ. in ***,the hierarchical one‐dimensional/three‐dimensional nitrog.n‐doped porous carbon(1D/3D NPC)is prepared by carbonizing.the composite of Zn‐MOF‐74 crystals in situ g.own on a commercial melamine spong.(MS),for electrochemical CO_(2)reduction reaction(CO_(2)RR).The 1D/3D NPC exhibits a hig. CO/H_(2)ratio(5.06)and CO yield(31 mmol g.(−1)h^(−1))at−0.55 V,which are 13.7 times and 21.4 times those of 1D porous carbon(derived from Zn‐MOF‐74)and N‐doped carbon(carbonized by MS),*** is attributed to the unique spatial environment of 1D/3D NPC,which increases the adsorption capacity of CO_(2)and promotes electron transfer from the 3D N‐doped carbon framework to 1D carbon,improving.the reaction kinetics of CO_(2)*** results and charg. density difference plots indicate that the active site of CO_(2)RR is the positively charg.d carbon atom adjacent to g.aphitic N on 1D carbon and the active site of HER is the pyridinic N on 1D *** presence of pyridinic N and pyrrolic N reduces the number of electron transfer,decreasing.the reaction kinetics and the activity of CO_(2)*** CO/H_(2)ratio is related to the distribution of N species and the specific surface area,which are determined by the deg.ee of spatial confinement *** CO/H_(2)ratios can be reg.lated by adjusting.the carbonization temperature to adjust the deg.ee of spatial confinement *** the low cost of feedstock and easy strateg.,1D/3D NPC catalysts have g.eat potential for industrial application.

关键词： electrochemical CO_(2)reduction reaction melamine spong. metal‐org.nic frameworks porous carbon syng.s

银川市大气臭氧生成敏感性与VOCs来源解析

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环境科学 2024年第8期45卷 4419-4431页

作者：杨丽蓉许萌徐学哲严晨冰余雪银川市生态环境监测站银川750001 中国科学院合肥物质科学研究院安徽光学精密机械研究所合肥230031 安徽中科蓝壹信息科技有限公司合肥230000

基于银川市2022年O_(3)浓度观测数据,分析了O_(3)浓度月变化特征,并基于5~7月银川市城区站点的气象要素、常规污染物和VOCs浓度观测数据,比较了污染日与非污染日的气象要素及前体物浓度的差异,并利用0维大气框架模型(FOAM)和正定矩阵因... 详细信息

基于银川市2022年O_(3)浓度观测数据,分析了O_(3)浓度月变化特征,并基于5~7月银川市城区站点的气象要素、常规污染物和VOCs浓度观测数据,比较了污染日与非污染日的气象要素及前体物浓度的差异,并利用0维大气框架模型(FOAM)和正定矩阵因子分解(PMF)模型探讨了O_(3)生成敏感性及VOCs主要来源.结果表明:①2022年银川市O_(3)污染出现在5~7月,ρ(O_(3)-8h_(-90per))分别为156、170和174μg.m^(-3),超标率分别为9.7%、26.7%和29.0%.②O_(3)污染日的气温、太阳总辐射和各类前体物浓度小时均值相较于非污染日均有所升高,其中丙烷、异丁烷、乙烷、正丁烷和二氯甲烷体积分数较非O_(3)污染时期增加显著,分别增加了33.1%、29.1%、25.0%、22.7%和21.3%,污染物排放增加及不利气象条件共同促进了O_(3)的生成.③5~7月整体、非污染日和污染日VOCs物种OFP值排名前5的物种一致,均为乙醛、间/对-二甲苯、乙烯、异戊二烯和甲苯,主要来自溶剂使用源、天然源和化工行业排放.④本地O_(3)生成多处于VOCs控制区,相对增量反应活性(RIR)分析表明污染日和非污染日O_(3)生成均对烯烃和芳香烃的敏感性较强,而NO_x为负敏感性,丙酮、乙烯和异丁烷等活性物种对于O_(3)生成的贡献较高,实施VOCs与NO_x减排比例远大于1的减排方案可有效降低本地O_(3)浓度.⑤银川市大气VOCs主要来源为机动车排放源(32.3%)、工艺过程源(20.7%)、燃烧源(19.2%)、溶剂使用源(12.7%)、汽油挥发源(9.1%)和天然源(6%),并且污染日机动车排放源贡献率较非污染日增加4.6%,说明机动车排放源是银川市夏季VOCs管控的重要对象.

关键词：臭氧(O_(3)) 臭氧敏感性分析 F0AM模型 VOCs来源解析正定矩阵因子分解(PMF)模型

Computational Experiments for Complex Social Systems:Experiment Desig. and g.nerative Explanation

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IEEE/CAA Journal of Automatica Sinica 2024年第4期11卷 1022-1038页

作者： Xiao xue Deyu Zhou Xiang.ing.Yu g.ng.Wang.Juanjuan Li Xia Xie Lizhen Cui Fei-Yue Wang the School of Computer Software College of Intelligence and ComputingTianjin UniversityTianjin 300350China the School of Software and the Joint SDUNTU Centre for Artificial Intellig.nce Research(C-FAIR) Shandong UniversityJinan 250101China the Information School Xi’an University of Financial and EconomicsXi’an 710100China the State Key Laboratory of Multimodal Artificial Intellig.nce Systems Institute of AutomationChinese Academy of SciencesBeijing 100190China Hainan University Haikou 570228China the State Key Laboratory for Manag.ment and Control of Complex Systems Institute of AutomationChinese Academy of SciencesBeijing 1001901China

Powered by advanced information technolog.,more and more complex systems are exhibiting.characteristics of the cyber-physical-social systems(CPSS).In this context,computational experiments method has emerg.d as a novel approach for the desig.,analysis,manag.ment,control,and integ.ation of CPSS,which can realize the causal analysis of complex systems by means of“alg.rithmization”of“counterfactuals”.However,because CPSS involve human and social factors(e.g.,autonomy,initiative,and sociality),it is difficult for traditional desig. of experiment(DOE)methods to achieve the g.nerative explanation of system *** address this challeng.,this paper proposes an integ.ated approach to the desig. of computational experiments,incorporating.three key modules:1)Descriptive module:Determining.the influencing.factors and response variables of the system by means of the modeling.of an artificial society;2)Interpretative module:Selecting.factorial experimental desig. solution to identify the relationship between influencing.factors and macro phenomena;3)Predictive module:Building.a meta-model that is equivalent to artificial society to explore its operating.***,a case study of crowd-sourcing.platforms is presented to illustrate the application process and effectiveness of the proposed approach,which can reveal the social impact of alg.rithmic behavior on“rider race”.

关键词： Ag.nt-based modeling computational experiments cyber-physical-social systems(CPSS) g.nerative deduction g.nerative experiments meta model

qg.11a/OsCAT8,encoding.an amino acid permease,neg.tively reg.lates g.ain size and weig.t in rice

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The Crop Journal 2024年第4期12卷 1150-1158页

作者： Peng.g.o Feifan Chen Haitang.Liu Shijun Fan Jierui Zeng.xue Diao yang Liu Wencheng.Song.Shifu Wang.Jing.Li Xiaobo Zhu Bin Tu Weilan Chen Ting.Li Yuping.Wang.Bing.ian Ma Shig.i Li Hua Yuan Peng.Qin State Key Laboratory of Crop g.ne Exploration and Utilization in Southwest China Rice Research InstituteSichuan Agricultural UniversityChengdu 611130SichuanChina

g.ain size is a key factor influencing.g.ain weig.t in *** this study,a chromosome seg.ent substitution line(CSSL9-17)was identified,that exhibits a sig.ificant reduction in both g.ain size and weig.t compared to its donor parent *** investig.tion identified two quantitative trait loci(QTL)on chromosome 11,desig.ated qg.11a and qg.11b,which contribute to 1000-g.ain weig.t with an additive ***_Os11g.5690,encoding.the amino acid permease OsCAT8,is the targ.t g.ne of *** of OsCAT8 resulted in decreased g.ain weig.t,while OsCAT8 knockout mutants exhibited increased g.ain *** 287-bp located within the OsCAT8 promoter reg.on of 93-11 neg.tively reg.lates its activity,which is subsequently correlated with an increase in g.ain size and *** results sug.est that OsCAT8 functions as a neg.tive reg.lator of g.ain size and g.ain weig.t in rice.

关键词： Rice g.ain size g.ain weig.t QTL OsCAT8

Polypyride intercalation boosting.the kinetics and stability of V_(3)O_(7)·H_(2)O cathodes for aqueous zinc-ion batteries

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Journal of Energ. Chemistry 2024年第10期97卷 361-370,I0007页

作者： Qing.ing.He Jie Bai Meng.a xue Yanxin Liao Huayu Wang.Mujun Long.Ling.un Chen Department of Applied Chemistry School of Chemistry and Chemical EngineeringChongqing UniversityChongqing 41331China Laboratoryof Materials and Metallurg. Cllege of Materials Science and EngineeringChongqing UniversityChongqing 400044Chin

V_(3)O_(7)·H_(2)O(VO)is a hig. capacity cathode material in the field of aqueous zinc ion batteries(AZIBs),but it is limited by slow ion mig.ation and low electrical *** this paper,polypyridine(PPyd)intercalated VO with nanoribbon structure was prepared by a simple in-situ pre-intercalation,which is noted *** total density of states(TDOS)shows that after the pre-intercalation of PPyd,an intermediate energ. level appears between the valence band and conduction band,which provides a step that can effectively reduce the band g.p and enhance the electron ***,the density functional theory(DFT)results found that Zn^(2+)is more easily de-intercalated from the V-O skeleton,which proves that the embeddedness of PPyd improves the diffusion kinetics of Zn^(2+).Electrochemical studies have shown that VO-PPyd cathode materials exhibit excellent rate performance(hig. specific capacity of 465 and 192 mA h g.(-1)at 0.2 and 10 A g.(-1),respectively)and long.term cycling.performance(92.7%capacity retention rate after 5300 cycles),due to their advantag.s in structure and *** importantly,the energ. density of VO-PPyd//Zn at 581 and 5806 W kg.(-1)is 375 and 247 W h kg.(-1),***-PPyd exhibits excellent electrochemical properties compared to previously reported vanadium based cathodes,which makes it hig.ly competitive in the field of hig.-performance cathode materials of AZIBs.

关键词： V_(3)O_(7)·H_(2)O Polypyridine Ion mig.ation Electrical conductivity Aqueous zinc ion batteries DFT calculation

Self-assemble construction of hetero-structured Co（OH）2/MXene aerog.l toward Li-S batteries as a self-supported host and bifunctional catalyst

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Rare Metals 2024年第11期 5652-5663页

作者： yang Liu Ke Tan Sen Liu Xu Zhang.Mao-Qiang.Shen xue-Sen Liu Xin-Yue g.o Lin-Rui Hou Chang.Zhou Yuan School of Materials Science & Eng.neering University of Jinan

The shuttling.diffusion of polysulfides is a bottleneck that seriously limits the performance of Li-S *** construction of sulfur cathodes with reliable trapping.ability of polysulfides is the key to overcome such ***,a hierarchical porous architecture,i.e.,Co（OH）2sheets bonded Ti3C2TxMXene aerog.l(Co（OH）2/MXA),is constructed via a facile selfassembled approach and used as an efficient free-standing.polysulfides *** interconnected three-dimensional（3D） porous network with void space and strong.interfacial interaction not only enables hig. sulfur loading.but facilitates fast ion and electron *** and theoretical results confirm the hetero-framework exhibits outstanding.immobilization and conversion ability for polysulfides due to its polar surface and bifunctional catalytic activities toward both formation and decomposition of *** optimized Co（OH）2/MXA cathode delivers excellent rate capability(407 mAh·g.1at 5C) with a sulfur loading.of 2.7 mg.cm-2,and ultra-stable cycling.performance as an extremely small capacity decay of～0.005% per cycle within 1700 cycles at 1C is achieved with a hig. sulfur loading.of 6.7 mg.*** sig.ificantly,our desig. structural/componential methodolog. here promises the MXene-based aerog.l electrodes for LiS batteries and beyond.

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