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A neural regulation mechanism of head electroacupuncture on brain network of patients with stroke related sleep disorders

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Journal of Traditional Chinese Medicine 2024年第6期44卷 1268-1276页

作者： ZHANG Boyang ZHOU Yang FENG Liyuan sui Dan HE Lei TONG Dan WANG Ruoyu sui xue SONG Jing WANG Dongyan Rehabilitation Department Wuxi Hospital of Traditional Chinese MedicineWuxi 214000China Imaging Department Harbin Medical University Cancer HospitalHarbin 150000China Acu-Moxi DepartmentⅢ the Second Affiliated Hospital of Heilongjiang University of Traditional Chinese MedicineHarbin 150000China Rehabilitation Department B Second Hospital of HarbinHarbin 150000China Acu-Moxi Department Lianyungang Hospital of Traditional Chinese MedicineLianyungang 222000China Integrated TCM and Western Medicine Department Suzhou Dushu lake hospitalSuzhou 215000China Internal Medicine Department Zhaozhou Hospital of Traditional Chinese MedicineDaqing 163000China

OBJECTIVE: To analyze part of the mechanism of electroacupuncture on Sishencong(EX-HN1) for strokerelated sleep disorders(SSD) and post-stroke cognitive impairment(PSCI). METHODS: Using a randomized controlled trial(RCT) design, 72 patients were assigned to the electroacupuncture(EA) group or the sham acupuncture(SA) group. A healthy control(HC) group was also included. Both groups were given routine rehabilitation treatment. Then, patients in the EA group were given additional electroacupuncture at Sishencong(EX_HN1). Meanwhile, patients in the SA group were given a flat-head needle sham/placebo treatment placed at the bilateral Jianyu (LI15) and Binao(LI14) line midpoints and the Jianyu(LI15) and Jianzhen(SI9) line midpoints. Before and after treatment, scales were collected and analyzed. In the second phase of the study, some subjects from the EA group were selected for functional magnetic resonance imaging(f MRI) data acquisition and comparative analysis with the HC group using a non-RCT design. RESULTS: The EA group performed better than the SA group on the Pittsburgh sleep quality index(PSQI), Montreal cognitive assessment basic(Mo CA_B), selfrating anxiety scale(SAS), and self-rating depression scale(SDS). Analysis of the f MRI showed that lowfrequency(2 Hz) electroacupuncture stimulation at Sishencong(EX_HN1) can restrain frontal sup medial right(SFGmed.R), precuneus right(PCUN.R), and posterior cingulate cortex right(PCC.R) and enhance angular left(ANG.L), parietal inf left(IPL.L) and occipital mid left(MOG.L). The functional connectivity(FC) of SFGmed.R was positively correlated with PSQI. Electroacupuncture stimulation at Sishencong(EX_HN1) can reduce the side efficiency of the whole brain connection with the Thalamus.L, Hippocampus.L, and ***.L. CONCLUSIONS: Low frequency(2 Hz) electroacupuncture stimulation at Sishencong(EX_HN1) can simultaneously improve sleep quality, negative emotions, and cognitive functions, the first two of which may be

关键词： electroacupuncture brain network neural regulation sleep disorder

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Preparation of multi-walled carbon nanotube-reinforced TiNi matrix composites from elemental powders by spark plasma sintering

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Rare Metals 2012年第1期31卷 48-50页

作者： CAI Wei,FENG xue,and sui Jiehe National Key Laboratory Precision Hot Processing of Metals,School of Materials Science and Engineering,Harbin Institute of Technology,Harbin 150001,China National Key Laboratory Precision Hot Processing of Metals School of Materials Science and Engineering Harbin Institute of Technology Harbin China

Carbon nanotube (CNT)-reinforced TiNi matrix composites were synthesized by spark plasma sintering (SPS) employing elemental *** phase structure,morphology and transformation behaviors were *** was found that thermoelastic martensitic transformation be-haviors could be observed from the samples sintered above 800 ℃ even with a short sintering time (5min),and the transformation tempera-tures gradually increased with increasing sintering temperature because of more Ti-rich TiNi phase *** decreasing the sin-tering temperature and time to 700 ℃ and 5min could not protect defective MWCNTs from reacting with Ti,still-perfect MWCNTs re-mained in the specimens sintered at 900 ℃.This method is expected to supply a basis for preparing CNT-reinforced TiNi composites.

关键词： metallic composites shape memory materials carbon nanotubes spark plasma sintering

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Enjoying Women's Work

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Women of China 1998年第9期 17-18页

作者： sui xue JENNIFER LIM

FATE is full of opportunities. Before going to college, I studied in a middle school in the suburban area of Changchun, Jilin Province. Because I studied hard, I had been a cadre in class. Some villagers said, "This girl is so capable. She could take charge of the work concerning women in our village." I was very glad to hear these words.

关键词： Enjoying Women’s Work

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Effect of Traditional Chinese Medicine on the Growth and Invasion of Human First Trimester Cytotrophoblasts in vitro

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Journal of Reproduction and Contraception 2008年第2期19卷 73-82页

作者： Hai-yan WANG Qin-di ZOU xue-lian LI sui-qi GUI Gynecology ＆ Obstetrics Hospital Fudan University Shanghai 200011 China

Objective To investigate the effect of Traditional Chinese Medicine（TCM） on the growth and invasion of human first trimester cytotrophoblasts in vitro.Methods Serum contained drug was collected from rats adiministered with herbs intragastricly. Serum collected from rats administered with saline was used as the control. Isolated from first trimester placental tissues, human cytotrophoblast cultured in media with 5%, 10%, 20% drug-containing serum for a 24 h, 48 h or 72 h period. Then cell morphology was measured by scanning electric microscope, cell viability by MTT assay, cell DNA content by flow cytomester, and cell invasion by transwell assay.Results After a 48 h- and 72 h-culture period in media with drug-containing rat serum, cytotrophoblast showed more and longer cell pseudopodia than control cells. In addition, cytotrophoblast exhibited more cell microvillous than control cells after a 72 h culture with drug-containing serum. Cell viability cultured with drug-containing serum was higher than control cells. Cells cultured with drug-containing serum in S phase were more, by contrast, in sub-G1 and G2/M phase were less than the control. Cells cultured with drug-containing serum for 72 h showed significantly greater invasive ability than control cells.Conclusion TCM had a beneficial role in the growth and invasion of human first trimester cytotrophoblast in vitro.

关键词： Traditional Chinese Medicine(TCM) cytotrophoblast proliferation invasion

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Estimating Aboveground Fresh Biomass of Different Cotton Canopy Types with Homogeneity Models Based on Hyper Spectrum Parameters

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Agricultural Sciences in China 2007年第4期6卷 437-445页

作者： BAI Jun-hu LI Shao-kun WANG Ke-ru sui xue-yan CHEN Bing WANG Fang-yong Institute of Crop Sciences Chinese Academy of Agricultural Sciences/The National Key Facility for Crop Gene Resources and Genetic Improvement NFCRI Beijing 100081 P.R.China Key Laboratory of Oasis Ecology Agriculture of Xinjiang Construction Crops/The Center of Crop High-Yield Research Shihezi 832003 P.R.China

AGB （aboveground fresh biomass） is one of the most important parameters of the crop condition monitored with remote sensing. Hyper spectrum remote sensing with the fine spectrum information becomes the efficient method estimating the vegetation AGB. The research was conducted in Xinjiang, the largest cotton planting region of China. The paper analyzed the correlation between the cotton AGB and reflective spectrum and the first derivative spectrum, and the variation coefficient of the waveband reflectance. According to the analysis above, all of 23 parameters, including the hyper spectrum reflectance, the first derivative spectrum parameters and normalization vegetation indexes, were established. And then the estimation models on cotton AGB of relaxing and compact canopy type were established and tested respectively. The tested results showed that Fgo1, [901,502], [901,629], [901,672] among the reflective spectral parameters and D525, D956, D1019, D1751 among the first derivative spectral parameters had the homogenous effect on different cotton canopy types, and the determination coefficients of the models above all arrive at the significant level of 0.99 confidence interval. At last, the tested results of the homogeneity models for different canopy types indicated the parameters of [901, 502], [901,629], [901,672] have more satisfying veracity than others, and the relative errors are as low as 17.0, 16.3 and 16.7% correspondingly; in contrast, the estimation veracity of the first derivative spectrum parameters of single waveband is low.

关键词： canopy types of cotton AGB hyperspectrum parameters homogeneity estimation models

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住宅辐射-送风末端冷负荷分担率研究——从热舒适及室内空气品质角度

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土木建筑与环境工程 2011年第5期33卷 114-120页

作者：隋学敏张旭长安大学环境科学与工程学院西安710054 长安大学国土资源部干旱半干旱地区水资源与国土环境开放研究实验室西安710054 同济大学暖通空调及燃气研究所上海200092

以住宅建筑为研究对象,针对低、中、高负荷3种不同住宅负荷工况,对不同冷负荷条件下不同负荷分担率下的室内热环境进行了数值模拟,分别分析比较不同冷负荷分担率匹配时室内热舒适性水平及室内空气品质情况,从舒适和健康的角度,分析适宜... 详细信息

以住宅建筑为研究对象,针对低、中、高负荷3种不同住宅负荷工况,对不同冷负荷条件下不同负荷分担率下的室内热环境进行了数值模拟,分别分析比较不同冷负荷分担率匹配时室内热舒适性水平及室内空气品质情况,从舒适和健康的角度,分析适宜的冷负荷分担率范围。研究结果表明辐射供冷末端承担的显热负荷分担率ωc<0.7时,可将工作区人体热舒适性指标控制在舒适性标准允许范围内。从避免局部不舒适度方面讲,ωc宜取0.4～1。从室内空气品质角度讲,定风量模式低中负荷工况,ωc宜取0.5～0.9,高负荷工况,ωc宜取0.35～0.6;变风量模式,ωc值越小,室内空气品质越好。

关键词：辐射供冷送风冷负荷分担率热舒适空气品质

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Aerolysin Nanopore Identification of Single Nucleotides Using the AdaBoost Model

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Journal of Analysis and Testing 2019年第2期3卷 134-139页

作者： xue-Jie sui Meng-Yin Li Yi-Lun Ying Bing-Yong Yan Hui-Feng Wang Jia-Le Zhou Zhen Gu Yi-Tao Long School of Information Science and Engineering East China University of Science and TechnologyShanghai 200237China School of Chemistry and Molecular Engineering East China University of Science and TechnologyShanghai 200237China

Nanopores employ the ionic current from the single molecule blockage to identify the structure,conformation,chemical groups and charges of a single *** the tremendous development in designing sensitive pore-forming materials,at some extent,the analyte with the single group difference still exhibits similar residual current or duration *** serious overlap in the statistical results of residual current and duration time brings the difficulties in the nanopore discrimination of each single molecules from the *** this paper,we present the AdaBoost-based machine learning model to identify the multiple analyte with single group difference in the mixed blockages.A set of feature vectors which is obtained from Hidden Markov Model(HMM)is used to train the AdaBoost *** employing the aerolysin sensing of 5ʹ-AAAA-3ʹ(AA3)and 5ʹ-GAAA-3ʹ(GA3)as the model system,our results show that AdaBoost model increases the identification accu-racy from~0.293 to above ***,five sets of mixed blockages of AA3 and GA3 further validate the average accuracy of training and validation,which are 0.997 and 0.989,*** proposed methods improve the capacity of wild-type biological nanopore in efficiently identify the single nucleotide difference without designing of protein and optimizing of the experimental ***,the AdaBoost-based machine learning approach could promote the nanopore practical application such as genetic and epigenetic detection.

关键词： Nanopore single nucleotide discrimination Single molecule analysis AdaBoost Hidden Markov model

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学习困难儿童观看图片的眼动研究

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中国特殊教育 2006年第8期 61-65页

作者：隋雪辽宁师范大学心理系大连116029

本文探讨了学习困难儿童(学困儿童)观看图片过程的认知加工及眼动特性。要求被试观看图片后回答相关问题,并对观看过程中的眼动情况进行记录。结果发现,与学习优秀儿童、学习一般儿童相比,学困儿童提取图片信息的效率低,完成认知任务的... 详细信息

本文探讨了学习困难儿童(学困儿童)观看图片过程的认知加工及眼动特性。要求被试观看图片后回答相关问题,并对观看过程中的眼动情况进行记录。结果发现,与学习优秀儿童、学习一般儿童相比,学困儿童提取图片信息的效率低,完成认知任务的质量差;在眼动参数上,学困儿童的注视次数多,眼跳距离小,与其他两组儿童相比差异显著。结果提示,学困儿童认知加工效率低与眼动模式差关系密切。

关键词：学习困难儿童观看图片认知加工眼动眼跳距离特殊教育

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Two forms of the membrane-bound state of the first C2 domain (C2A) of synaptotagminⅠand calcium-triggered membrane insertion

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Chinese Science Bulletin 2003年第17期48卷 1822-1827页

作者： HE Yuhong, LI Xianghui, WANG Fu, xue Yi & sui Senfang Department of Biological Sciences & Biotechnology, State Key Labora-tory of Biomembrane, Tsinghua University, Beijing 100084, China Department of Biological Sciences & Biotechnology State Key Laboratory of Biomembrane Tsinghua University Beijing China

The synaptic vesicle protein synaptotagminⅠ (sytⅠ) is a vesicle transmembrane protein present in synap-tic vesicles, which has been proposed as the Ca2+ sensor that regulates secretion. The C2A domain is the membrane proximal part of its cytoplasmic domain. The interaction between C2A and lipid bilayer has been considered to be essential for triggering neurotransmitter release. In the pre-sent work, the measurements of membrane surface tension and surface concentration showed that the C2A domain of sytⅠexhibited two membrane-bound states: the surface adsorption state and the membrane insertion state. The sur-face absorption state formed in a Ca2+-independent manner with lower affinity, while the membrane insertion state formed with high affinity was only found in the presence of Ca2+. Both the Ca2+-independent and Ca2+-dependent sytⅠ- membrane interactions required anionic phospholipids, such as phosphatidylserine (PS). When expressed into rat pheo-chromocytoma (PC12) cells and human embryonic kidney (HEK-293) cells, as demonstrated by immunofluorescence staining and subcellular fractionation, most of the C2A was found at the plasma membrane, even when the cells were depleted of Ca2+ by incubation with EGTA. These results suggested a new molecular mechanism of sytⅠas a Ca2+ sensor in membrane fusion. Ca2+-independent surface ad-sorption might attach sytⅠto the release site during the docking or priming step. When intracellular Ca2+ increased, sytⅠtriggered the neurotransmitter release following the Ca2+-dependent penetration into the target membrane.

关键词：突触小泡蛋白质膜贯通蛋白质钙离子薄膜插入 C2A 薄膜边界状态

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Relationship of Abortion and the Expression of Indoleamine 2,3- dioxygenase (IDO) in Villus and Syncytiotrophoblasts

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Journal of Reproduction and Contraception 2005年第4期16卷 235-242页

作者： xue-lian LI sui-qi GUI Hai-yan WANG Department of Gynecology of lntegrated Traditional Chinese and Western Medicine The Hospital of Obstetric ＆ Gynecology Fudan University Shanghai 200011 China

Objective To study the relationship of abortion and the expression of indoleamine 2, 3- dioxygenase （IDO） in villus and syncytiotrophoblast in vitro. Methods RT-PCR was applied to analyze the mRNA transcription of lDO in villus of normal pregnancy and inevitable abortion and JAR cells as well. Immunohistochemistry was applied to analyze the expression of IDO protein in villus. Western blot was applied to determinate the expression of IDO protein on cultured syncytiotrophoblast. Highperformance liquid chromatography was applied to determinate whether there was kynurenine in cell culture medium of syncytiotrophoblast. Results The expression of IDO mRNA and protein in villus of inevitable abortion was lower than that of normal pregnancy; IDO mRNA did not express in JAR cells. IDO protein expressed on cultured syncytiotrophoblast, and there was kynurenine in cell culture medium of syncytiotrophoblast. Conclusion Appropriate expression of IDO in villus is *** maintenance of normal pregnancy and an active IDO protein expresses in syncytiotrophoblast.

关键词： indoleamine 2,3-dioxygenase syncytiotrophoblast villus abortion

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