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Reflectance confocal microscopy characteristics for melanocytic nevi

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Chinese Medical Journal 2019年第20期132卷 2510-2511页

作者： Yan Jing Chang-Bing shen Ke xue Cheng-Xu Li xue shen Zi-Yi Wang Feng Xu Ru-Song Meng Jian-Bin Yu Yong Cui Department of Dermatology The First Affiliated Hospital of Anhui Medical UniversityHefeiAnhui 230032China Department of Dermatology China-Japan Friendship HospitalBeijing 100029China Graduate School Peking Union Medical College and Chinese Academy of Medical SciencesBeijing 100730China Shanghai Wheat Color Intelligent Technology Company LimitedShanghai 200051China Department of Dermatology Specialty Medical Center of the Air ForcePeople's Liberation ArmyBeijing 100142China Department of Dermatology The First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan 450052China.

To the Editor: Melanocytic nevi are a common benign tumor disease in dermatology and can occur in all ages and parts of the skin surface. There are different clinical manifestations in pigmented nevus skin lesions. It is difficult to distinguish other diseases which have similar clinical manifestations of pigmented nevus if medical diagnosis is based solely on the color, shape, or clinical experience of the lesion. Nevi are mainly divided into three categories: junctional (melanocytes confined to the epidermis only), intra-dermal (confined to the dermis only), and compound (both an epidermal and a dermal component). The relationships between these three different types of nevi and what factors contribute to the formation of one type vs. another are still unclear.[1]

关键词： clinical diagnosis diseases

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建材行业智能化发展现状及展望

新型工业化 2024年第2期14卷 5-9页

作者：秦松沈雪中国建筑材料联合会北京100083 建筑材料工业信息中心北京100083

智能制造是制造强国建设的主攻方向,是新型工业化的重要特征。本文总体介绍了近年来建材行业智能化发展取得的积极进展,重点分析了水泥、玻璃、陶瓷领域推进智能制造取得的成效,从智能装备、技术创新和推广应用等方面分析了建材行业智... 详细信息

智能制造是制造强国建设的主攻方向,是新型工业化的重要特征。本文总体介绍了近年来建材行业智能化发展取得的积极进展,重点分析了水泥、玻璃、陶瓷领域推进智能制造取得的成效,从智能装备、技术创新和推广应用等方面分析了建材行业智能化发展的趋势,指出了建材行业智能化发展存在的不足,并提出相关建议。

关键词：智能制造零一线员工工业互联网发展趋势

基于层次分析法的门诊公共空间韧性设计要素评价研究

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当代建筑 2024年第1期 133-136页

作者：申雪王珊中国建筑设计研究院有限公司北京工业大学城建学院

在综合医院发展面临新的需求与挑战的背景下,本文首先将韧性理论模型引入综合医院门诊公共空间的设计研究中,构建基于韧性视角的门诊公共空间韧性发展机制;其次,利用层次分析法和系统文献研究法,通过客观分析明确空间环境的影响因子,系... 详细信息

在综合医院发展面临新的需求与挑战的背景下,本文首先将韧性理论模型引入综合医院门诊公共空间的设计研究中,构建基于韧性视角的门诊公共空间韧性发展机制;其次,利用层次分析法和系统文献研究法,通过客观分析明确空间环境的影响因子,系统地构建门诊公共空间韧性设计评价体系;最后,基于目标导向,从交通流线、等候区、服务空间等方面提出门诊公共空间的韧性优化策略,以期为综合医院的韧性提升提供新的理论基础与设计启发。

关键词：综合医院门诊公共空间韧性设计层次分析法

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融合双分支动态偏好的会话推荐

计算机系统应用 2024年第3期33卷 52-62页

作者：沈学利王乐田学成辽宁工程技术大学软件学院葫芦岛125105

针对基于会话的推荐算法仅对用户单一偏好进行静态建模而无法捕捉用户受环境影响偏好产生的波动,从而降低推荐准确性的问题.提出融合双分支动态偏好的会话推荐方法:首先,通过异构超图来建模不同类型信息,设计双分支聚合机制获取以及整... 详细信息

针对基于会话的推荐算法仅对用户单一偏好进行静态建模而无法捕捉用户受环境影响偏好产生的波动,从而降低推荐准确性的问题.提出融合双分支动态偏好的会话推荐方法:首先,通过异构超图来建模不同类型信息,设计双分支聚合机制获取以及整合异构超图中信息并且学习多类型节点之间的关系,再用价格嵌入增强器来加强类别和价格之间关系;其次,设计双层偏好编码器,其中采用多尺度时序Transformer提取用户动态价格偏好,利用软注意机制和反向位置编码学习用户动态兴趣偏好;最后,用门控机制融合用户多类型动态偏好,向用户进行推荐.通过在Cosmetics和Diginetica-buy两个数据集上进行实验,结果证明与其他对比算法相比在Precision和MRR评价指标中有显著的提升.

关键词：推荐系统多类型动态建模异构超图双分支注意力机制

Pharmacological Effects and Mechanisms of Sclareol

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Medicinal Plant 2022年第4期13卷 8-11页

作者： Yuqi LI Qian CHEN xue shen Shuang LI Bocui SONG Chenghao JIN Molecular Mechanism of Disease&Research and Development of Bioactive Substances College of Life Science&TechnologyHeilongjiang Bayi Agricultural UniversityDaqing 163319China Department of Pharmaceutical Engineering College of Life Science&TechnologyHeilongjiang Bayi Agricultural UniversityDaqing 163319China College of Food Science&Technology Heilongjiang Bayi Agricultural UniversityDaqing 163319China National Coarse Cereals Engineering Research Center Daqing 163319China

This paper first reviewed the pharmacological effects and mechanisms of Sclareol in recent years.It discussed anti-inflammatory effects,antibacterial,and anti-photoaging effects of Sclareol.It is expected to lay a the... 详细信息

关键词： Sclareol Anti-inflammatory Anti-photoaging Anti-tumor

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基于YOLOv8n的无人机航拍目标检测

计算机系统应用 2024年第7期33卷 139-148页

作者：沈学利王灵超辽宁工程技术大学软件学院葫芦岛125105

针对无人机航拍检测任务中小目标检测精度低的问题,提出一种基于YOLOv8n的目标检测算法(SFEYOLO).首先,嵌入浅层特征增强模块,将输入特征的浅层空间信息与颈部获取的深层语义信息融合,以增强小目标特征表示能力,并使用全局上下文块(GC-B... 详细信息

针对无人机航拍检测任务中小目标检测精度低的问题,提出一种基于YOLOv8n的目标检测算法(SFEYOLO).首先,嵌入浅层特征增强模块,将输入特征的浅层空间信息与颈部获取的深层语义信息融合,以增强小目标特征表示能力,并使用全局上下文块(GC-Block)对融合信息进行重校准,抑制背景噪声.其次,引入可变形卷积来代替C2F中的部分标准卷积,提高网络对几何变化的适应性.再次,引入ASPPF模块,融合平均池化技术,增强模型对多尺度特征的表达并降低漏检率.最后,在颈部网络的基础上嵌入中尺度特征合成层,融合主干网络中更多的中间特征,使不同尺度的特征过渡更平滑,并通过跳跃连接增强特征重用性.该模型在数据集VisDrone2019和VOC2012上进行验证,mAP@0.5值达到30.5%和67.3%,相较于基线算法YOLOv8n提升了3.6%和0.8%,能够提升无人机图像目标检测性能,同时具有较好的泛化性.

关键词：无人机检测浅层特征融合 ASPPF YOLOv8n 中尺度特征融合

激光诱导击穿光谱技术对钕铁硼永磁材料中多元素的定量表征

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光谱学与光谱分析 2024年第1期44卷 141-147页

作者：刘佳郭飞飞于雷崔飞鹏赵迎韩冰沈学静王海舟钢铁研究总院北京100081 钢研纳克检测技术股份有限公司纳克研究院北京100081

“磁王”钕铁硼是现今性能最为优异的永磁体,因其优异的磁性能被广泛应用于工业互联网、新能源、 5G通讯等诸多高新科技领域。目前研究钕铁硼材料中元素成分的主要分析方法有电感耦合等离子体发射光谱(ICP-OES)和X射线荧光光谱(XRF),其... 详细信息

“磁王”钕铁硼是现今性能最为优异的永磁体,因其优异的磁性能被广泛应用于工业互联网、新能源、 5G通讯等诸多高新科技领域。目前研究钕铁硼材料中元素成分的主要分析方法有电感耦合等离子体发射光谱(ICP-OES)和X射线荧光光谱(XRF),其中ICP-OES是湿法分析,样品前处理复杂,测试周期长,而XRF法可实现直接分析,但受制于其轻元素的检测能力很难满足对钕铁硼材料中主要轻元素B的分析需求。激光诱导击穿光谱(LIBS)技术具有分析效率高,样品前处理简单,多元素直接分析,适用于现场分析、在线分析等技术优点,使其在快速定量表征方面展现出其独有的优势。运用LIBS分析技术开展对钕铁硼材料中多元素定量表征的直接、快速分析的方法研究,首先针对钕铁硼材料中定量表征的九个元素Nd、 Co、 B、 Dy、 Tb、 Pr、 Cu、 Al、 Ga完成特征谱线的筛选,通过对系统激光器电压、激光剥蚀方式等因素在不同条件下对钕铁硼材料光谱信号稳定性的影响分析,优化并确立了分析条件,最终选用720V的激光器电压,15个预剥蚀脉冲15个剥蚀脉冲的激光剥蚀方式为钕铁硼样品的分析条件;其次,选取8个通过ICP-OES法定值的烧结钕铁硼样品,样品具有元素成分的梯度差异化特征,作为建立分析方法的标准样品,采用标准曲线法通过相对强度与浓度的关联方式,建立钕铁硼样品中Nd、 Co、 B、 Dy、 Tb、 Pr、 Cu、 Al、 Ga九个元素的定量分析校准曲线;最后选取两个烧结钕铁硼试样,运用建立的定量分析方法完成九个元素的定量表征,分析时间小于30 s,其定量结果与ICP-OES法测定结果的比对,具有较好的一致性。运用激光诱导击穿光谱分析技术实现了对钕铁硼材料中多元素成分的直接、同时、快速定量表征,为钕铁硼材料的快速定量表征提供了新的技术思路和表征方法。

关键词：激光诱导击穿光谱钕铁硼定量表征

Skin diseases in the Da Qing Diabetes Study:a cross-sectional study

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Chinese Medical Journal 2021年第10期134卷 1191-1198页

作者： Chang-Bing shen Xin Qian Rui-Xing Yu xue-Lei Ji Yin-Juan Shi Jing Gao Cheng-Xu Li Ke-Ke Li Wen-Min Fei xue shen Zi-Yi Wang Yang Han Xiao-Li Ning Randy Ko Yi-Hsiang Hsu Xian-Yong Yin Guang-Wei Li Yong Cui Department of Dermatology Peking University Shenzhen HospitalShenzhenGuangdong 518036China shenzhen Key Laboratory for Translational Medicine of Dermatology Shenzhen Peking University-The Hong Kong University of Science and Technology Medical CenterShenzhenGuangdong 518036China Hinda and Arthur Marcus Institute for Aging Research Hebrew SeniorLife and Harvard Medical SchoolBostonMA 02131USA Center of Endocrinology and Cardiology Fu Wai HospitalChinese Academy of Medical SciencesBeijing 100037China Department of Dermatology China-Japan Friendship HospitalBeijing 100029China Institute of Skin Health China-Japan Friendship HospitalBeijing 100029China Department of Endocrinology and Metabolism Second People’s Hospital of WuhuWuhuAnhui 241000China Department of Dermatology First Affiliated Hospital of Soochow UniversitySuzhouJiangsu 215006China Department of Dermatology Second Affiliated HospitalAnhui Medical UniversityHefeiAnhui 230601China Graduate School Peking Union Medical College and Chinese Academy of Medical SciencesBeijing 100730China Department of Dermatology Chengdu Second People’s HospitalChengduSichuan 610017China The University of New Mexico School of Medicine AlbuquerqueNM 87131USA Broad Institute of MIT and Harvard CambridgeMA 02142USA Department of Biostatistics Center for Statistical GeneticsUniversity of MichiganAnn ArborMI 48109USA Department of Endocrinology China-Japan Friendship HospitalBeijing 100029China

Background:The prevalence of skin diseases and diabetes mellitus(DM)are prominent around the world.The current scope of knowledge regarding the prevalence of skin diseases and comorbidities with type 2 DM(T2DM)is limited,leading to limited recognition of the correlations between skin diseases and T2DM.Methods:We collected 383 subjects from the Da Qing Diabetes Study during the period from July 9th to September 1st,2016.The subjects were categorized into three groups:Normal glucose tolerance(NGT),impaired glucose tolerance(IGT),and T2DM.The prevalence and clinical characteristics of skin diseases were recorded and investigated.Results:In this cross-sectional study,383 individuals with ages ranging from 53 to 89-year-old were recruited.The overall prevalence of skin diseases was 93.5%,and 75.7%of individuals had two or more kinds of skin diseases.Additionally,there were 47 kinds of comorbid skin diseases in patients with T2DM,of which eight kinds of skin diseases had a prevalence>10%.The prevalence of skin diseases in NGT,IGT,and T2DM groups were 93.3%,91.5%,and 96.6%,respectively;stratified analysis by categories showed a statistically significant difference in"disturbances of pigmentation"and"neurological and psychogenic dermatoses".The duration of T2DM also significantly associated with the prevalence of"disturbances of pigmentation"and"neurological and psychogenic dermatoses".Subsequently,the prevalence of"disturbances of pigmentation"was higher in males than females in NGT(P<0.01)and T2DM(P<0.01)groups.In addition,the difference in the prevalence of"disturbances of pigmentation"was also significant in NGT and T2DM groups(P<0.01).Conclusions:There was a high prevalence of skin diseases in the Da Qing Diabetes Study.To address the skin diseases in the Da Qing Diabetes Study,increased awareness and intervention measures should be implemented.

关键词： Skin diseases Type 2 diabetes mellitus Prevalence Comorbidities

Hybridized 1T/2H-MoS_(2)/graphene fishnet tube for high-performance on-chip integrated micro-systems comprising supercapacitors and gas sensors

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Nano Research 2021年第1期14卷 114-121页

作者： Chi Zhang Jing Ning Boyu Wang Haibin Guo Xin Feng xue shen Yanqing Jia Jianguo Dong Dong Wang Jincheng Zhang Yue Hao The State Key Discipline Laboratory of Wide Band Gap Semiconductor Technology Xidian UniversityXian 710071China Shaanxi Joint Key Laboratory of Graphene Xidian UniversityXian 710071China

The emerging micro-nano-processing technologies have propelled significant advances in multifunctional systems that can perform multiple functions within a small volume through integration.Herein,we present an on-chip multifunctional system based on a 1T/2H-MoS_(2)/graphene fishnet tube,where a micro-supercapacitor and a gas sensor are integrated.A hybrid three-dimensional stereo nanostructure,including M0S_(2) nanosheets and graphene fishnet tubes,provides K^(+)ions with a short diffusion pathway and more active sites.Owing to the large layer spacing of IT-M0S_(2) promoting fast reversible diffusion,the on-chip micro-supercapacitor exhibits excellent electrochemical properties,including an areal capacitance of 0.1 F·cm^(-2)(1 mV·s^(-1)).The variation in the conductivity of 2H-MoS_(2) when ammonia molecules are adsorbed as derived from the first-principles calculations proves the Fermi level-changes theory.Driven by a micro-supercapacitor,the responsivity of the gas sensor can reach 55.7%at room temperature(27℃).The multifunctional system demonstrates the possibility of achieving a two-dimensional integrated system for wearable devices and wireless sensor networks in the future.

关键词： multifunctional system integrate 1T/2H-MoS_(2) supercapacitor gas sensor