检索结果-南通市图书馆

Clinical study of chemotherapy-related cognitive impairment in patients with non-Hodgkin lymphoma

World Journal of Psychiatry 2024年第7期14卷 1062-1067页

作者： qiang-Li Wang Hai-Yan Xu Yi Wang yin-Ling Wang Pei-Nan Lin Zhong-Lei Chen Department of Oncology and Hematology Suzhou Kowloon HospitalShanghai Jiao Tong University School of MedicineSuzhou 215000Jiangsu ProvinceChina

BACKGROUND Chemotherapy for malignant tumors can cause brain changes and cognitive impairment,leading to chemotherapy-induced cognitive impairment(CICI).Current research on CICI has focused on breast cancer and Hodgkin’s *** patients with non-Hodgkin’s lymphoma(NHL)undergoing chemo-therapy have cognitive impairment has not been fully *** have cognitive impairment has not been fully *** To investigate whether NHL patients undergoing chemotherapy had cognitive *** The study included 100 NHL patients who were required to complete a compre-hensive psychological scale including the Brief Psychiatric Examination Scale(MMSE)at two time points:before chemotherapy and within 2 wk of two chemo-therapy courses.A language proficiency test(VFT),Symbol Number Pattern Test(SDMT),Clock Drawing Test(CDT),Abbreviated Daily Cognition Scale(ECog-12),Prospective and Retrospective Memory Questionnaire,and Karnofsky Perfor-mance Status were used to assess cognitive changes before and after *** The VFT scores for before treatment(BT)and after treatment(AT)groups were 45.20±15.62,and 42.30±17.53,respectively(t-2.16,P<0.05).The CDT scores were 8(3.5-9.25)for BT and 7(2.5-9)for AT groups(Z-2.1,P<0.05).Retrospective memory scores were 13.5(9-17)for BT and 15(13-18)for AT(Z-3.7,P<0.01).The prospective memory scores were 12.63±3.61 for BT and 14.43±4.32 for AT groups(t-4.97,P<0.01).The ECog-12 scores were 1.71(1.25-2.08)for BT and 1.79(1.42-2.08)for AT groups(Z-2.84,P<0.01).The SDMT and MMSE values did not show a significant difference between BT and AT *** Compared to the AT group,the BT group showed impaired language,memory,and subjective cognition,but objec-tive cognition and execution were not significantly affected.

关键词： Non-Hodgkin’s lymphoma Hodgkin lymphoma Lymphoma cognitive impairment Chemotherapy-related cogni-tive impairment Clinical study

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Decomposition of pre-existing Au–P clusters induced in situ a-Fe grains uniformization in Fe–P-based nanocrystalline alloys

引用

Rare Metals 2024年第10期43卷 5242-5255页

作者： Min-Hao Han Cheng Sun Guo-Guo Xi Yang Meng qiang Luo xue-Qian Yu Wen-Feng Zhang Hao Liu Hong-Jie Xu Tao Zhang Key Laboratory of Aerospace Materials and Performance(Ministry of Education) School of Materials Science and EngineeringBeihang University Laboratory of Functional Fiber Materials Institute of Bast Fiber CropsChinese Academy of Agricultural Science School of Materials Science and Engineering Jiangsu Key Laboratory for Advanced Metallic MaterialsSoutheast University Institute for Advanced Materials North China Electric Power University Center for Advanced Analysis and Computational Science Zhengzhou University

In Fe-based amorphous-/nanocrystalline ribbons,the uniformization and refinement of a-Fe grains are key aspects for optimizing their soft magnetic and mechanical ***,the Fe–P–C–B nanocrystalline alloy system was selected for *** produced as-spun ribbons with pre-existing nanocrystals through melt-quenching and then obtained a well-distributed a-Fe nanocrystalline structure through annealing below the first crystallization onset temperature （633 K）resulting in excellent magnetic properties (saturation magnetization of 1.65 T and coercivity of 1.6 A·m-1)ultra-wide annealing temperature window （from 613 to 733 K）,and extremely high annealing stability （up to 480 min at 633 K）.Furthermore,we propose a new in situ two-step mechanism for the uniformization of a-Fe nanocrystals,which is separately induced by the decomposition of the Au–P clusters and the pre-existing a-Fe nanocrystals during *** work underscores the crucial significance of micro-alloying via metastable clusters primarily influenced by metal-phosphide interactions in the process of refining a-Fe ***,i introduces a new principle for optimizing the comprehensive properties of Fe-based amorphous/nanocrystalline alloys.

关键词： Fe-based nanocrystalline alloys In-situ nano-crystallization Micro-alloying Soft magnetic property

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

FibroScan-aspartate transaminase:A superior non-invasive model for diagnosing high-risk metabolic dysfunction-associated steatohepatitis

引用

World Journal of Gastroenterology 2024年第18期30卷 2440-2453页

作者： Jing-Ya yin Tian-Yuan Yang Bing-Qing Yang Chen-xue Hou Jun-Nan Li Yue Li Qi Wang Center of Liver Diseases Beijing Ditan HospitalCapital Medical UniversityBeijing 100015China Department of Pathology Beijing Ditan HospitalCapital Medical UniversityBeijing 100015China Beijing institute of infectious disease Beijing 100015China Beijing Key Laboratory of Emerging Infectious Diseases Institute of Infectious DiseasesBeijing Ditan HospitalCapital Medical UniversityBeijing 100015China

BACKGROUND Non-alcoholic fatty liver disease(NAFLD)with hepatic histological NAFLD activity score≥4 and fibrosis stage F≥2 is regarded as“at risk”non-alcoholic steatohepatitis(NASH).Based on an international consensus,NAFLD and NASH were renamed as metabolic dysfunction-associated steatotic liver disease(MASLD)and metabolic dysfunction-associated steatohepatitis(MASH),respectively;hence,we introduced the term“high-risk MASH”.Diagnostic values of seven non-invasive models,including FibroScan-aspartate transaminase(FAST),fibrosis-4(FIB-4),aspartate transaminase to platelet ratio index(APRI),*** high-risk MASH have rarely been studied and compared in *** To assess the clinical value of seven non-invasive models as alternatives to liver biopsy for diagnosing high-risk *** A retrospective analysis was conducted on 309 patients diagnosed with NAFLD via liver biopsy at Beijing Ditan Hospital,between January 2012 and December *** screening for MASLD and the exclusion criteria,279 patients wereincluded and categorized into high-risk and non-high-risk MASH *** threshold values of each model,sensitivity,specificity,positive predictive value(PPV),and negative predictive values(NPV),were *** operating characteristic curves were constructed to evaluate their diagnostic efficacy based on the area under the curve(AUROC).RESULTS MASLD diagnostic criteria were met by 99.4%patients with *** MASLD population was analyzed in two cohorts:Overall population(279 patients)and the subgroup(117 patients)who underwent liver transient elastography(FibroScan).In the overall population,FIB-4 showed better diagnostic efficacy and higher PPV,with sensitivity,specificity,PPV,NPV,and AUROC of 26.9%,95.2%,73.5%,72.2%,and ***,Forns index,and aspartate transaminase to alanine transaminase ratio(ARR)showed moderate diagnostic efficacy,whereas S index and gamma-glutamyl transpeptidase to platelet ratio(GPR)were relatively *** the sub

关键词： Metabolic dysfunction-associated steatotic liver disease High-risk metabolic dysfunction-associated steatohepatitis Non-invasive models Liver biopsy Diagnostic value

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Selective Alkane Desaturation Catalyzed by Molecular Cage Copper Complexes Under Mild Conditions

引用

CCS Chemistry 2024年第8期6卷 1876-1884页

作者： Hao Sun xue-Yuan Wang Xu-Dong Wang Yu-Fei Ao De-Xian Wang Qi-qiang Wang Beijing National Laboratory for Molecular Sciences CAS Key Laboratory of Molecular Recognition and FunctionInstitute of ChemistryChinese Academy of SciencesBeijing 100190 University of Chinese Academy of Sciences Beijing 100049

Catalytic oxidative alkane desaturation by base metals with benign oxidants under mild conditions is highly attractive,as it could enable an efficient way to produce valuable olefin *** we report the design and synthesis of macrocyclic and molecular cage copper complexes in catalyzing highly selective cyclohexane desaturation with H_(2)O_(2)/O_(2).The macrocycles and cages possess two to three phenanthroline units connected by versatile binary linkers or tripodal *** compounds readily formed bi-and tri-nuclear copper complexes with confined cavities and adaptive coordination environments,as suggested by X-ray single crystal *** the catalytic oxidation of cyclohexane,a considerable yield of cyclohexene with unprecedented dehydrogenation/oxygenation selectivity up to 6.1:1 was achieved with the optimal cage compound *** and mechanistic experiments suggested a pronounced cage effect and radical-mediated *** high selectivity was attributed to a cooperative effect between the copper centers,which facilitated the second hydrogen atom abstraction on the trapped cyclohexyl radical and the inhibition of the Fenton process within the shielding cavity environment.

关键词： supramolecular catalysis macrocycles molecular cages phenanthroline alkane desaturation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

I-DCGAN and TOPSIS-IFP:A simulation generation model for radiographic flaw detection images in light alloy castings and an algorithm for quality evaluation of generated images

引用

China Foundry 2024年第3期21卷 239-247页

作者： Ming-jun Hou Hao Dong Xiao-yuan Ji Wen-bing Zou Xiang-sheng Xia Meng Li Ya-jun yin Bao-hui Li qiang Chen Jian-xin Zhou State Key Laboratory of Materials Processing and Die&Mould Technology Huazhong University of Science and TechnologyWuhan 430074China Xinjiang Technology(Jiangsu)Co. Ltd.Nantong 226100JiangsuChina Southwest Technique and Engineering Research Institute Chongqing 400039China Shanghai Spaceflight Precision Machinery Institute Shanghai 201600China

The intelligent detection technology driven by X-ray images and deep learning represents the forefront of advanced techniques and development trends in flaw detection and automated evaluation of light alloy ***,the efficacy of deep learning models hinges upon a substantial abundance of flaw *** existing research on X-ray image augmentation for flaw detection suffers from shortcomings such as poor diversity of flaw samples and low reliability of quality *** this end,a novel approach was put forward,which involves the creation of the Interpolation-Deep Convolutional Generative Adversarial Network(I-DCGAN)for flaw detection image generation and a comprehensive evaluation algorithm named TOPSIS-IFP.I-DCGAN enables the generation of high-resolution,diverse simulated images with multiple appearances,achieving an improvement in sample diversity and quality while maintaining a relatively lower computational ***-IFP facilitates multi-dimensional quality evaluation,including aspects such as diversity,authenticity,image distribution difference,and image distortion *** results indicate that the X-ray radiographic images of magnesium and aluminum alloy castings achieve optimal performance when trained up to the 800th and 600th epochs,*** TOPSIS-IFP value reaches 78.7%and 73.8%similarity to the ideal solution,*** to single index evaluation,the TOPSIS-IFP algorithm achieves higher-quality simulated images at the optimal training *** approach successfully mitigates the issue of unreliable quality associated with single index *** image generation and comprehensive quality evaluation method developed in this paper provides a novel approach for image augmentation in flaw recognition,holding significant importance for enhancing the robustness of subsequent flaw recognition networks.

关键词： light alloy casting flaw detection image generator discriminator comprehensive evaluation index

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effects of dense planting patterns on photosynthetic traits of different vertical layers and yield of wheat under different nitrogen rates

引用

The Crop Journal 2024年第2期12卷 594-604页

作者： Cuicun Wang Ke Zhang Qing Liu Xiufeng Zhang Zhikuan Shi xue Wang Caili Guo qiang Cao Yongchao Tian Yan Zhu Xiaojun Liu Weixing Cao National Engineering and Technology Center for Information Agriculture Nanjing Agricultural UniversityNanjing 210095JiangsuChina MOE Engineering Research Center of Smart Agricultural Nanjing Agricultural UniversityNanjing 210095JiangsuChina MARA Key Laboratory for Crop System Analysis and Decision Making Nanjing Agricultural UniversityNanjing 210095JiangsuChina Jiangsu Key Laboratory for Information Agriculture Nanjing Agricultural UniversityNanjing 210095JiangsuChina Institute of Smart Agriculture Nanjing Agricultural UniversityNanjing 210095JiangsuChina

A two-year field experiment was conducted to measure the effects of densification methods on photosynthesis and yield of densely planted ***-plant and inter-row distances were used to define ratefixed pattern(RR)and row-fixed pattern(RS)density ***,four nitrogen(N)rates(0,144,192,and 240 kg N ha-1,termed N0,N144,N192,and N240)were applied with three densities(225,292.5,and 360×10^(4)plants ha^(-1),termed D225,D292.5,and D360).The wheat canopy was clipped into three equal vertical layers(top,middle,and bottom layers),and their chlorophyll density(Ch D)and photosynthetically active radiation interception(FIPAR)were *** showed that the response of Ch D and FIPAR to N rate,density,and pattern varied with different layers.N rate,density,and pattern had significant interaction effects on Ch *** maximum values of whole-canopy Ch D in the two seasons appeared in N240 combined with D292.5 and D360 under RR,*** two growing seasons,FIPAR values of RR were higher than those of RS by 29.37%for the top layer and 5.68%for the middle layer,while lower than those of RS by 20.62%for the bottom layer on *** a low N supply(N0),grain yield was not significantly affected by density for both *** N240,increasing density significantly increased yield under RR,but D360 of RS significantly decreased yield by 3.72%and 9.00%versus D225 in two seasons,*** an appropriate and sufficient N application,RR increased the yield of densely planted wheat more than ***,the maximum yield in two seasons appeared in the combination of D360 with N144 or N192 rather than of D225 with N240 under both patterns,suggesting that dense planting combined with an appropriate N-reduction application is feasible to increase photosynthesis capacity and yield.

关键词： Chlorophyll density Densification method Nitrogen Photosynthetically active radiation interception Wheat

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Broadband high-efficiency plasmonic metalens with negative dispersion characteristic

引用

Photonics Research 2024年第4期12卷 813-820页

作者： YONG-qiang LIU YONG ZHU HONGCHENG yin JINHAI SUN YAN WANG YONGXING CHE National Key Laboratory of Scattering and Radiation Beijing 100854China

Controlling the dispersion characteristic of metasurfaces(or metalenses) along a broad bandwidth is of great importance to develop high-performance broadband metadevices. Different from traditional lenses that rely on the material refractive index along the light trajectory, metasurfaces or metalenses provide a new regime of dispersion control via a sub-wavelength metastructure, which is known as negative chromatic ***, broadband metalenses design with high-performance focusing especially with a reduced device dimension is a significant challenge in society. Here, we design, fabricate, and demonstrate a broadband highperformance diffractive-type plasmonic metalens based on a circular split-ring resonator metasurface with a relative working bandwidth of 28.6%. The metalens thickness is only 0.09λ0(λ0is at the central wavelength),which is much thinner than previous broadband all-dielectric metalenses. The full-wave simulation results show that both high transmissive efficiency above 80%(the maximum is even above 90%) and high average focusing efficiency above 45%(the maximum is 56%) are achieved within the entire working bandwidth of 9–12 ***, an average high numerical aperture of 0.7(NA = 0.7) of high-efficiency microwave metalens is obtained in the simulations. The broadband high-performance metalens is also fabricated and experimental measurements verify its much higher average focusing efficiency of 55%(the maximum is above 65% within the broad bandwidth) and a moderate high NA of 0.6. The proposed plasmonic metalens can facilitate the development of wavelength-dependent broadband diffractive devices and is also meaningful to further studies on arbitrary dispersion control in diffractive optics based on plasmonic metasurfaces.

关键词： resonator dispersion high

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Characteristics of the Deep Crustal Structure of the Greenland–Iceland–Faroe Ridge in the North Atlantic

引用

Acta Geologica Sinica(English Edition) 2024年第S1期 87-89页

作者： ZHANG Chunguan LI Fengyuan ZHANG qiang ZHANG Guoli HU Hongchuan yin Rui School of Earth Sciences and Engineering Xi'an Shiyou University Shaanxi Key Laboratory of Petroleum Accumulation Geology Xi'an Shiyou University Institute of Geophysical and Geochemical Exploration CAGS Tianjin Center China Geological Survey

The Greenland–Iceland–Faroe Ridge, located between the central eastern part of Greenland and the northwestern edge of Europe, spans across the North Atlantic. As the core component of the Greenland–Iceland–Faroe Ridge, the Iceland is an alkaline basalt area, which belongs to the periodic submarine magmatism and submarine volcano eruption resulting from mantle plume upwelling(Jiang et al., 2020). For the oceanic plateaus, the characteristics of the Iceland are closest to the continental crust, so the Iceland is considered the most suitable for simulating the earliest continental crust on the Earth(Reimink et al., 2014).

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Flash nanocomplexation (FNC): A new microvolume mixing method for nanomedicine formulation

引用

Chinese Chemical Letters 2024年第10期35卷 39-52页

作者： Keyang Li Yanan Wang Yatao Xu Guohua Shi Sixian Wei xue Zhang Baomei Zhang qiang Jia Huanhua Xu Liangmin Yu Jun Wu Zhiyu He Frontiers Science Center for Deep Ocean Multispheres and Earth Systems Key Laboratory of Marine Chemistry Theory and TechnologyMinistry of Education/Sanya Oceanographic InstitutionOcean University of ChinaQingdao/Sanya 266100/572024China College of Chemistry and Chemical Engineering Ocean University of ChinaQingdao 266003China School of Materials Science and Engineering Tsinghua UniversityBeijing 100084China Guangzhou City Polytechnic Guangzhou 510520China National Key Laboratory for the Modernization of Classical and Famous Prescriptions of Chinese Medicine Jiangxi University of Chinese MedicineNanchang330004China Division of Life Science The Hong Kong University of Science and TechnologyHong Kong SAR 999077China

The application of nanotechnologies in formulation has significantly promoted the development of modern medical and pharmacological science, especially for nanoparticle-based drug delivery, bioimaging, and theranostics. The advancement of engineering particle design and fabrication is largely supported by a better understanding of how their apparent characteristics(e.g., size and size distribution, surface morphology, colloidal stability, chemical composition) influence their in vivo biological performance, which raises an urgent need for practical nanoformulation methods. Based on turbulent flow mixing and the self-assembly of molecules in fluids, flash technologies emerged as effective bottom-up fabrication strategies for effective nanoformulation. Among the flash technology family, flash nanocomplexation(FNC) is considered a novel and promising candidate that can promote and optimize formulation processes in a precise spatiotemporal manner, thus obtaining excellent fabrication efficiency, reproducibility and expandability. This review presents an overview of recent advances in fabricating drug-delivery nanoparticles using FNC platforms. Firstly, brief introductions to the basic principles of FNC technology were carried out, followed by descriptions of turbulent microvolume mixers that have significantly promoted the efficiency of FNC-based fabrications. Applications of real formulation cases were then categorized according to the self-assembly-driven interactions(including electrostatic interaction, coordination interaction,hydrogen bonding and hydrophobic interaction) and discussed to reveal the progressiveness of fabricating nanoparticles and discuss how its flexibility will provide advances and replenish the philosophy of nanomedicine formulation. In the end, the commercial potential, current limitations, and prospects of FNC technology for nanoformulation will be summarized and discussed.

关键词： Nanoformulation Nanoparticles Self-assembly Flash nanocomplexation Kinetic control Drug delivery

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A three-way electrolyte with ternary solvents for high-energy-density and long-cycling lithium-sulfur pouch cells

引用

SusMat 2024年第2期4卷 1-12页

作者： Zheng Li Legeng Yu Chen-Xi Bi Xi-Yao Li JinMa Xiang Chen xue-qiang Zhang Aibing Chen Haoting Chen Zuoru Zhang Li-Zhen Fan Bo-Quan Li Cheng Tang qiang Zhang Tsinghua Center for Green Chemical Engineering Electrification Beijing Key Laboratory of Green Chemical Reaction Engineering and TechnologyDepartment of Chemical EngineeringTsinghua UniversityBeijingChina School of Materials Science and Engineering Beijing Institute of TechnologyBeijingChina Institute of Advanced Materials and Technology University of Science and TechnologyBeijingChina Shanxi Research Institute for Clean Energy Tsinghua UniversityTaiyuanChina Center for Next-Generation Energy Materials and School of Chemical Engineering Sungkyunkwan UniversityJangan-GuSuwon-SiGyeonggi-DoRepublic of Korea College of Chemical and Pharmaceutical Engineering Hebei University of Science and TechnologyShijiazhuangChina Ordos Carbon Neutral Research and Application Co. Ltd.Kangbashi DistrictOrdos CityInner MongoliaChina Institute for Carbon Neutrality Tsinghua UniversityBeijingChina

Lithium–sulfur(Li–S)batteries promise high-energy-density potential to exceed the commercialized lithiumion batteries but suffer from limited cycling lifespan due to the side reactions between lithium polysulfides(LiPSs)and Li metal ***,a three-way electrolyte with ternary solvents is proposed to enable high-energy-density and long-cycling Li–S pouch ***,ternary solvents composed of 1,2-dimethoxyethane,di-isopropyl sulfide,and 1,3,5-trioxane are employed to guarantee smooth cathode kinetics,inhibit the parasitic reactions,and construct a robust solid electrolyte interphase,*** cycling lifespan of Li–S coin cells with 50μm Li anodes and 4.0 mg cm^(−2) sulfur cathodes is prolonged from88 to 222 cycles using the three-way ***-heterogeneous solvation structure of LiPSs and organic-rich solid electrolyte interphase are identified to improve the cycling stability of Li metal ***,a 3.0 Ah-level Li–S pouch cell with the three-way electrolyte realizes a high energy density of 405 Wh kg^(−1) and undergoes 27 *** affords a three-way electrolyte recipe for suppressing the side reactions of LiPSs and inspires rational electrolyte design for practical high-energy-density and long-cycling Li–S batteries.

关键词： lithium metal anodes lithium-sulfur batteries pouch cells solid electrolyte interphase three-way electrolyte

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：