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A review:Research on corrosive sulphur in electrical power equipment

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High Voltage 2022年第2期7卷 209-221页

作者： Yuan Yuan xue gao Jiang Zhou Guoyong Liu Xiongwei Kuang Lijun Yang Ruijin Liao College of Materials Science and Engineering Chongqing UniversityChongqingChina The State Key Laboratory of Power Transmission Equipment&System Security and New Technology Chongqing UniversityChongqingChina

Corrosive sulphur has been commonly regarded as an enormous threat to electrical power equipment in recent *** sulphide(Cu2S)deposition on the insulating oil and paper insulation caused by sulphur corrosion will bring about insulation deteriorations or failures in power transformers and shunt reactors.A large number of experiments have been carried out to investigate sulphur corrosion and some measures have been come up to solve this issue such as replacement of insulating oil,chemical removal of corrosive sulphur and the addition of passivator and so ***,there has not been a perfect method to work out this problem completely,and the phenomenon of sulphur corrosion still *** paper intends to provide thorough information of corrosive sulphur in power equipment and give detailed explanations about its corrosion mechanism,hazards and control measures,which is supposed to offer a reference for subsequent researchers.

关键词： corrosion sulphur electrical

学龄前儿童家长儿童保健知识知晓现状调查及影响因素分析

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中国妇幼卫生杂志 2024年第4期15卷 43-48页

作者：张楠高雪婷王雯罗丹滕炜西北妇女儿童医院陕西西安710061

目的了解学龄前儿童家长儿童保健知识知晓现状,并分析其影响因素,为探索学龄前儿童保健服务策略提供研究依据。方法选取2023年8月-2024年1月在陕西省西安市西北妇女儿童医院儿童保健门诊进行健康体检的学龄前儿童家长997例为调查对象... 详细信息

目的了解学龄前儿童家长儿童保健知识知晓现状,并分析其影响因素,为探索学龄前儿童保健服务策略提供研究依据。方法选取2023年8月-2024年1月在陕西省西安市西北妇女儿童医院儿童保健门诊进行健康体检的学龄前儿童家长997例为调查对象,通过问卷星上的自制版儿童保健知识调查问卷收集儿童家长的人口学特征、儿童保健知识知晓情况及获取途径,采用二元logistic回归模型分析相关影响因素。结果共回收有效问卷981份,回收率为98.40%。学龄前儿童家长儿童保健知识知晓率为32.01%(314/981),对适当身体活动时间及频次、儿童视力及口腔保健、适当观看电子视频时间及频次、学龄前儿童生长发育异常情况4项内容知晓率均<50%。医护人员、微信/抖音/百度等平台是儿童家长获取保健知识的常见途径,占比分别为56.47%和55.66%。单因素分析结果显示,学龄前儿童家长不同文化程度、职业和知识获取途径种类的比较差异均有统计学意义(均P <0.05)。Logistic影响因素分析结果显示,大专及以上学历(OR=2.812,95%CI:1.190~6.649)、多种知识获取途径(OR=2.826,95%CI:1.143~6.990)的学龄前儿童家长的儿童保健知识知晓率较高(均P <0.05)。结论学龄前儿童家长儿童保健知识知晓率偏低,且受文化程度、知识获取途径种类等因素影响,应针对不同特征人群采取多渠道儿童保健知识宣传教育,以提升家长育儿水平。

关键词：学龄前儿童家长儿童保健知识影响因素

Single Goss grain growth by isothermal annealing in rolled Fe–Al–Ga–Nb C sheets

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Rare Metals 2023年第10期42卷 3537-3544页

作者： Yang-Yang Liu Ji-Heng Li Xiao-Long Li Xing Mu Xiao-Qian Bao xue-Xu gao State Key Laboratory for Advanced Metals and Materials University of Science and Technology BeijingBeijing100083China

The(Fe_(82)Al_(13.5)Ga_(4.5))_(99.9)(NbC)_(0.1) sheets with strong Goss texture and large magnetostriction were prepared by rolling and isothermal annealing *** Goss grain growth was observed in sheets undergoing isothermal annealing at 1050 ℃ for 1 h using Ar as protecting *** annealing time increasing to 8 h at1050℃,a largest magnetostriction of 154×10^(-6) is obtained in sheet and a large λ_(//)(the maximum magnetostriction with magnetic field parallel to rolling direction)of 160×10^(-6) along the rolling direction is also *** fact that a λ_(//) of 160×10^(-6) along RD can be achieved with only 4.5 at% Ga in the Fe-18 at%(Al,Ga) sheet is of practical *** with previous studies in Fe-Al and Fe-Ga sheets,this paper provides a more efficient approach to prepare strong Goss textured *** this way,a slow continuous heating process,sulfur-induced surface energy control and high-temperature annealing above 1200 ℃ are no more *** shows a good prospect for industrial production of high-performance magnetostrictive alloy sheets.

关键词： Fe–Al–Ga sheet Isothermal annealing Goss texture Magnetostriction

BlockBuster喉上通气装置与Supreme喉罩通气道在腹腔镜手术患者气道管理中应用效果比较

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中华实用诊断与治疗杂志 2024年第2期38卷 184-188页

作者：高学张加强张辉李超申军梅苏凯薛富善田鸣首都医科大学附属北京友谊医院麻醉科北京100050 河南省人民医院郑州大学人民医院麻醉与围术期医学科河南郑州450003 河北医科大学第四医院麻醉科河北石家庄050011

目的比较BlockBuster喉上通气装置与Supreme喉罩通气道在全身麻醉下择期腹腔镜手术患者气道管理中的应用效果及安全性。方法2016年4月—2017年3月首都医科大学附属北京友谊医院、河南省人民医院、河北医科大学第四医院行全身麻醉下择期... 详细信息

目的比较BlockBuster喉上通气装置与Supreme喉罩通气道在全身麻醉下择期腹腔镜手术患者气道管理中的应用效果及安全性。方法2016年4月—2017年3月首都医科大学附属北京友谊医院、河南省人民医院、河北医科大学第四医院行全身麻醉下择期腹腔镜手术患者118例,根据术中使用的通气装置分为BlockBuster组60例(BlockBuster喉上通气装置)和Supreme组58例(Supreme喉罩通气道),比较2组通气装置插入时间、插入成功率、定位及性能情况(通气试验阳性率、胸骨上凹试验阳性率、胃管插入试验阳性率、气道密封压、镜检定位分级)、位置调整情况、胃液引流量、通气罩充气量、手术时间、通气装置应用时间、腹腔镜气腹压及术中并发症(漏气、气道梗阻、通气罩染血、口腔活动性出血、反流、误吸)、术后并发症(咽痛、吞咽困难)发生情况。结果BlockBuster组通气装置气道密封压[(29.5±4.5)cmH2O]高于Supreme组[(27.0±3.3)cmH_(2)O](t=3.436,P0.05)。BlockBuster组手术时间、通气装置应用时间、腹腔镜气腹压,术中漏气、气道梗阻、通气罩染血、口腔活动性出血、反流、误吸及术后咽痛、吞咽困难比率与Supreme组比较差异均无统计学意义(P>0.05)。结论BlockBuster喉上通气装置和Supreme喉罩通气道均是全身麻醉下择期腹腔镜手术中安全、有效的气道管理工具,但BlockBuster喉上通气装置的气道密封性能优于Supreme喉罩通气道。

关键词：腹腔镜手术全身麻醉气道管理 BlockBuster喉上通气装置 Supreme喉罩通气道

Clinical application of free/total PSA ratio in the diagnosis of prostate cancer in men over 50 years of age with total PSA levels of 2.0-25.0 ng ml^(−1) in Western China

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Asian Journal of Andrology 2022年第2期24卷 195-200页

作者： xue-Dan gao Qiang Miao Jun-Long Zhang Jian-Zhao Zhai xue-Mei Gui Yi-Han Cai Qian Niu Bei Cai Department of Laboratory Medicine/Research Center of Clinical Laboratory Medicine West China Hospital of Sichuan UniversityChengdu 610041China Department of Laboratory Medicine Nan’an Chinese Medicine HospitalChongqing 400060China

The goal of this study was to investigate the clinical application of free/total prostate-specific antigen(F/T PSA)ratio,considering the new broad serum total PSA(T-PSA)“gray zone”of 2.0–25.0 ng ml^(−1)in differential diagnosis of prostate cancer(PCa)and benign prostate diseases(BPD)in men over 50 years in Western China.A total of 1655 patients were included,528 with PCa and 1127 with *** T-PSA,free PSA(F-PSA),and F/T PSA ratio were *** operating characteristic curves were used to assess the efficiency of PSA and F/T PSA *** were 47.4%of cancer patients with T-PSA of 2.0–25.0 ng ml^(−1).When T-PSA was 2.0–4.0 ng ml^(−1),4.0–10.0 ng ml^(−1),and 10.0–25.0 ng ml^(−1),the area under the curve(AUC)of F/T PSA ratio was 0.749,0.769,and 0.761,*** best AUC of F/T PSA ratio was 0.811 when T-PSA was 2.0–25.0 ng ml^(−1),with a specificity of 0.732,a sensitivity of 0.788,and an optimal cutoff value of 15.5%.The AUC of F/T PSA ratio in different age groups(50–59 years,60–69 years,70–79 years,and≥80 years)was 0.767,0.806,0.815,and 0.833,respectively,and the best sensitivity(0.857)and specificity(0.802)were observed in patients over 80 *** T-PSA trend was in accordance with the Gleason score,tumor node metastasis(TNM)stage,and American Joint Committee on Cancer prognosis ***,the F/T PSA ratio can facilitate the differential diagnosis of PCa and BPD in the broad T-PSA“gray zone”.Serum T-PSA can be a Gleason score and prognostic indicator.

关键词： free/total prostate-specific antigen ratio gray zone prostate-specific antigen prostate cancer total prostate-specific antigen

Vedolizumab-associated diffuse interstitial lung disease in patients with ulcerative colitis:A case report

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World Journal of Clinical Cases 2022年第5期10卷 1716-1722页

作者： Jie Zhang Mei-Hong Liu xue gao Chang Dong Yan-Xia Li Department of Pulmonary and Critical Care Medicine First Affiliated Hospital of Dalian Medical UniversityDalian 116011Liaoning ProvinceChina Department of Pathology First Affiliated Hospital of Dalian Medical UniversityDalian 116011Liaoning ProvinceChina

BACKGROUND Vedolizumab,a newer class of integrin antagonist biological agents,has been applied to treat patients with moderate-to-severe Crohn’s disease(CD)and ulcerative colitis(UC),especially for patients who are refractory to traditional therapies and tumor necrosis factor ***,some rare but lifethreatening adverse effects warrant *** describe the first fatal case of vedolizumab-associated severe diffuse interstitial lung disease in *** SUMMARY We present a case of new-onset diffuse parenchymal lung disease developing under treatment with vedolizumab in a patient with *** two doses of vedolizumab,he developed persistent fever and progressively worsening *** workups,including bronchoalveolar lavage,transbronchial lung biopsy and metagenomic next-generation sequencing,identified no infectious causes,and other potential causes(such as tumors and cardiogenic pulmonary edema)were also *** a result,a diagnosis of vedolizumabrelated interstitial lung disease was ***,although corticosteroids and empiric antibiotics were administered,the patient eventually died of respiratory *** Vedolizumab-related interstitial lung disease in patients with UC is rare but potentially *** and pulmonologists should be aware of vedolizumab-related adverse drug reactions.

关键词： Vedolizumab Adverse effects Ulcerative colitis Inflammatory bowel disease Interstitial lung disease Case report

牛MED28基因编码区克隆、生物信息学分析及组织表达谱研究

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中国畜牧兽医 2024年第8期51卷 3225-3236页

作者：李晋男王亚慧邓天宇梁忙杜丽丽李柯安宁薛青青骞里高雪张路培朱波陈燕王泽昭李俊雅高会江青岛农业大学动物科技学院青岛266109 中国农业科学院北京畜牧兽医研究所北京100193 黑龙江八一农垦大学动物科技学院大庆163319

[目的]克隆牛介体复合物亚单位28(mediator complex subunit 28,MED28)基因CDS区,预测MED28蛋白的结构功能,并分析MED 28基因在牛各组织中的表达水平,为后续研究MED 28基因的功能奠定基础。[方法]以牛成肌细胞RNA反转录的cDNA为模板,利... 详细信息

[目的]克隆牛介体复合物亚单位28(mediator complex subunit 28,MED28)基因CDS区,预测MED28蛋白的结构功能,并分析MED 28基因在牛各组织中的表达水平,为后续研究MED 28基因的功能奠定基础。[方法]以牛成肌细胞RNA反转录的cDNA为模板,利用PCR方法扩增并克隆牛MED 28基因CDS区。运用MegAlign、Mega 11.0软件进行MED28蛋白的相似性比对和系统进化树构建,利用ProtParam、ProtScale、SOPMA、SWISS-MODEL、MEME、STRING等在线软件分析MED28蛋白的理化性质及结构功能,并通过实时荧光定量PCR检测MED 28基因在牛心脏、肝脏、脾脏、肺脏、肾脏、小肠、肌肉组织中的表达量。[结果]试验成功克隆MED 28基因CDS区,长度为537 bp,编码178个氨基酸。相似性比对结果表明,牛MED28蛋白与山羊、绵羊的相似性最高;系统进化树显示,牛与山羊、绵羊的遗传距离最近,与鸡的遗传距离最远。MED28蛋白属于不稳定的亲水性蛋白,无跨膜区和信号肽,主要在细胞外发挥作用,含有2个N-糖基化位点和21个磷酸化位点。MED28蛋白二级结构由α-螺旋、β-转角、延伸链和无规则卷曲组成,其中α-螺旋占比最大,蛋白结构稳定,与三级结构预测结果一致。蛋白互作网络分析表明,MED28蛋白与其家族的多种蛋白之间存在互作,且主要在转录途径和甲状腺信号通路中发挥作用。MEME预测结果表明,MED28蛋白的保守基序在牛、人、猪、小鼠、马、兔、山羊、绵羊之间是相同的;MED28蛋白结构域有低复杂度和卷曲螺旋序列。实时荧光定量PCR结果表明,MED 28基因在牛肌肉组织中的表达量显著高于其他组织(P<0.05)。[结论]牛和羊的亲缘关系最近、蛋白相似性高。MED28蛋白亲水且结构稳定,存在N-糖基化位点和磷酸化位点,无跨膜区和信号肽,主要分布在细胞外,并参与转录途径和甲状腺信号通路。MED 28基因在牛肌肉组织中高表达。以上结果可为进一步研究牛MED 28基因的功能提供参考。

关键词：牛 MED 28基因克隆生物信息学

超高层建筑施工中起火预测及火灾模拟与人员疏散

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科学技术与工程 2024年第12期24卷 5114-5122页

作者：任浩王宪杰张林飞翁振江高雪莲陈永党云南大学建筑与规划学院中建交通建设集团有限公司云南分公司

超高层施工中起火因素多，火灾危害较大，疏散风险较高。为研究超高层施工中火灾发生情况与对应情况下的人员疏散问题，以招平商务中心项目施工现场为例，采用神经网络对火灾的起火材料进行预测，通过火灾动力学模拟工具进行火灾模拟仿... 详细信息

超高层施工中起火因素多，火灾危害较大，疏散风险较高。为研究超高层施工中火灾发生情况与对应情况下的人员疏散问题，以招平商务中心项目施工现场为例，采用神经网络对火灾的起火材料进行预测，通过火灾动力学模拟工具进行火灾模拟仿真，得到火灾烟气与温度的模拟数据，并在此基础上考虑恐慌和施工环境影响，对施工现场人员利用Pathfinder进行疏散研究。结果表明：该案例最可能的起火材料为保温材料，火灾时影响疏散的因素主要为温度与能见度，疏散者受恐慌情绪、火灾和施工环境影响后，疏散时间由324 s变为419 s。

关键词：施工火灾超高层建筑火灾动力学模拟工具(FDS) 疏散模拟神经网络

Depression in children with nephrotic syndrome related to parents’stress,quality of life,and depression

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World Journal of Pediatrics 2023年第2期19卷 194-199页

作者： Hui-Mei Huang Wei He xue-Yun gao Hong-Li Sun Ying Bao Department of Nephrology Xi’an Children’s HospitalXi’anChina Shaanxi Institute for Pediatric Diseases Xi’an Key Laboratory of Children’s Health and DiseasesXi’an Children’s HospitalXi’anChina School of Public Health Xi’an Jiaotong UniversityXi’anChina

Nephrotic syndrome(NS)is the most common glomerular disease in children,affecting about 7-16 in 100,000 children under 16 years old worldwide[1].Children with NS often experience significant emotional and behavioral problems,especially with frequent relapses,steroid dependence,steroid resistance,or maternal distress[2].Psychological stress may trigger proteinuria in children with steroid-sensitive nephrotic syndrome[3].The presence of NS in a child also causes burden on family members,especially the mother[4],in association with psychological distress.

关键词： distress mother stress