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泪小管炎的临床诊断和治疗

临床眼科杂志 2016年第5期24卷 441-443页

作者：杨晓钊杨华刘先宁郑璇张懿刘超陕西省眼科研究所陕西省眼科学重点实验室西安市第一医院西安710002

研究泪小管炎的主要致病菌及药物敏感性,探索泪小管炎治愈率高、损伤小、依从性好的治疗方法。方法选取西安市第一医院就诊的泪小管炎患者32例(32只眼),取泪小管分泌物行细菌培养及药敏试验;泪小管内排除的硫磺颗粒碾开涂片;用搔刮泪小... 详细信息

研究泪小管炎的主要致病菌及药物敏感性,探索泪小管炎治愈率高、损伤小、依从性好的治疗方法。方法选取西安市第一医院就诊的泪小管炎患者32例(32只眼),取泪小管分泌物行细菌培养及药敏试验;泪小管内排除的硫磺颗粒碾开涂片;用搔刮泪小管+挤压泪小管排出硫磺颗粒+抗生素凝胶注入泪小管+敏感抗生素点眼联合方法进行治疗。结果 32例泪小管炎患者中,有31例挤压泪小管见硫磺颗粒经泪点排出,取硫磺颗粒涂片均见放线菌。32例患者取泪小管分泌物进行细菌培养,31例为阳性,共培养出菌株37株,主要为表皮葡萄球菌、草绿色链球菌和肺炎球菌,其他菌种少见。药物敏感性试验结果显示:利福平、头孢西丁、氯霉素、美洛西林等药物敏感性较高。用泪小管搔刮+挤压排出硫磺颗粒+抗生素凝胶注入泪小管+敏感抗生素点眼联合方法治疗泪小管炎,治愈率可达84%以上。结论放线菌为泪小管炎的主要致病菌,且大部分存在与其他细菌的合并感染。利福平、头孢西丁、氯霉素、美洛西林等药治疗泪小管炎敏感性高。用联合方法治疗泪小管炎治愈率高,且损伤小,患者依从性高。

关键词：泪小管炎致病菌药物敏感性诊断治疗

Comprehensive bibliometric analysis of pharmacotherapy for bipolar disorders:Present trends and future directions

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World Journal of Psychiatry 2025年第1期15卷 153-167页

作者： Bo-Fan Chen Li liu Fang-Zhen Lin Hai-Min Zeng Hai-Qiang Huang Chun-Fang Zhang Cong-Cong liu Xiang Chen Jie Peng Yun-Fa Wang Zhi-Lin Wang Bin Chen De-Le liu Yun liu zheng-zheng Li Xin-Xing Zeng The Second Affiliated Hospital Jiangxi Medical CollegeNanchang UniversityNanchang 330006Jiangxi ProvinceChina The Second Clinical Medical College Jiangxi Medical CollegeNanchang UniversityNanchang 330006Jiangxi ProvinceChina Department of Rehabilitation Medicine The Second Affiliated HospitalJiangxi Medical CollegeNanchang UniversityNanchang 330006Jiangxi ProvinceChina Jiangxi Provincial People’s Hospital The First Affiliated Hospital of Nanchang Medical CollegeNanchang 330006Jiangxi ProvinceChina Department of Psychiatry Jiangxi Mental HospitalHospital of Nanchang UniversityNanchang UniversityNanchang 330029Jiangxi ProvinceChina

BACKGROUND Bipolar disorder(BD)is a severe mental illness characterized by significant mood *** drug treatment modalities are crucial for managing *** To analyze the current status and future trends of global research on BD drug treatment over the last *** The Web of Science Core Collection database spanning from 2015 to 2024 was utilized to retrieve literature related to BD drug treatment.A total of 2624 articles were *** visualization and analysis were conducted using CiteSpace,VOSviewer,Pajek,Scimago Graphica,and R-studio bibliometrix to identify RESULTS The United States,China,and the United Kingdom have made the most significant contributions to research on BD drug treatment and formed notable research collaboration *** University of Pittsburgh,Massachusetts General Hospital,and the University of Michigan have been identified as the major research institutions in this *** Journal of Affective Disorders is the most influential journal.A keyword analysis revealed research hotspots related to clinical symptoms,drug efficacy,and genetic mechanisms.A citation analysis identified the management guidelines published by Yatham et al in 2018 as the most cited *** This study provides a detailed overview of the field of BD drug treatment,highlighting key contributors,research hotspots,and future *** study findings can be employed as a reference for future research and policymaking,which may enable further development and optimization of BD pharmacotherapy.

关键词： Bipolar disorder Drug treatment Bibliometric analysis Visualization Mental disorder

IL-1α、IL-1β和TNF-α mRNA在实验性鼠根尖周炎中的表达

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上海口腔医学 2001年第1期10卷 16-18页

作者：梅陵宣刘正张濒上海第二医科大学附属第九人民医院口腔医学院口腔内科上海200011

目的　检测IL 1α、IL 1β和TNF αmRNA在鼠根尖周炎组织中的表达 ,了解上述细胞因子与根尖周炎的关系。方法　 16只SD大鼠第一、二磨牙开髓 ,分别于术后 3d、7d、14d、2 8d取磨牙根尖周组织 ,提取总RNA ,用RT PCR方法测定IL 1α、IL 1... 详细信息

目的　检测IL 1α、IL 1β和TNF αmRNA在鼠根尖周炎组织中的表达 ,了解上述细胞因子与根尖周炎的关系。方法　 16只SD大鼠第一、二磨牙开髓 ,分别于术后 3d、7d、14d、2 8d取磨牙根尖周组织 ,提取总RNA ,用RT PCR方法测定IL 1α、IL 1β和TNF αmRNA的表达 ,用看家基因 β Actin作内参照进行半定量分析。结果　术后 7d鼠根尖周组织中即有IL 1α、TNF α、IL 1βmRNA的表达 ,14d达高峰 ,2 8d有所下降 ,但IL 1α和TNF α的表达量大于IL 1β表达量 ,相差非常显著 (P <0 .0 1)。结论　IL 1α和TNF α可能是导致鼠根尖周炎的主要细胞因子。

关键词：根尖周炎 IL-1α IL-1β TNF-α mMRNA表达

Electro-optical properties cholesteric liquid of polymer stabilized crystal film＊

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Chinese Physics B 2011年第2期20卷 295-301页

作者： Ma Ji zheng Zhi-Gang liu Yong-Gang xuan Li State Key Laboratory of Applied Optics Changchun Institute of Optics Fine Mechanics and Physics Chinese Academy of Sciences Changchun 130033 China Department of Physics School of Science East China University of Science and Technology Shanghai 200237 China

Liquid crystals （LCs） and polymers are extensively used in various electro-optical applications. In this paper, normal mode polymer stabilized cholesteric LC film is prepared and studied. The effects of chiral dopant and monomer concentrations on the electro-optical properties, such as contrast ratio, driving voltage, hysteresis width and response time, are investigated. The reasons of electro-optical properties influenced by the concentrations of the materials are discussed. Through the proper material recipe, the electro-optical properties of polymer stabilized cholesteric LC film can be optimized.

关键词： liquid crystal polymer electro-optical property cholesteric liquid crystal

The Chang 7 member of the upper Triassic in the southwest Ordos Basin:Carbon isotope studay of dispersed organic matter and its paleoclimate significance

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Petroleum Science 2008年第1期5卷 20-23页

作者： Yang Minghui liu Chiyang Tang xuan zheng Xiaofeng Basin ＆ Reservoir Research Center Key Laboratory of Hydrocarbon Accumulation Ministry of Education ChinaUniversity of Petroleum Beijing 102249 China Department of Geology Northwest University Xi＇an 710069 Shaanxi China Department of Energy Geology China University of Geosciences Beijing 100083 China

The carbon isotope δ 13C value of dispersed organic matter in the Upper Triassic sediments in the Ordos basin is （-24.5 to -26.6） ×10^-3 with the carbon being derived from C3-1ike pleustons. The paleoclimate of the Late Triassic, especially during the deposition of the Chang 7 member, was characterized by a hot and humid climate. It underwent four small climate cycles from humid and warm to humid and hot.

关键词： Paleoclimate stable carbon isotope dispersed organic material Yanchang Formation Ordos basin

Symmetry Breaking for Black-Scholes Equations

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Communications in Theoretical Physics 2007年第6期47卷 995-1000页

作者： YANG xuan-liu ZHANG Shun-Li QU Chang-zheng School of Economics and Management Tsinghua University Beijing 100084 China Center for Nonlinear Studies Northwest University Xi＇an 710069 China Department of Mathematics Northwest University Xi＇an 710069 China

Black-Scholes equation is used to model stock option pricing. In this paper, optimal systems with one to four parameters of Lie point symmetries for Black-Scholes equation and its extension are obtained. Their symmetry breaking interaction associated with the optimal systems is also studied. As a. result, symmetry reductions and corresponding solutions for the resulting equations are obtained.

关键词： Black-Scholes equation symmetry optimal system symmetry breaking solution

Theoretical Studies of g Factors and Defect Structures for Cubic, Tetragonal, and Orthorhombic Fe^＋ Centers in Alkali Halides MX （M=Li, Na; X = F, C1）

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Communications in Theoretical Physics 2006年第1X期46卷 167-170页

作者： liu Hong-Gang WU Xiao-xuan zheng Wen-Chen Department of Material Science Sichuan University Chengdu 610064 China Department of Physics Civil Aviation Flying Institute of China Guanghan 618307 China International Centre for Materials Physics the Chinese Academy of Sciences Shenyang 110016 China

The EPR 9 factors for cubic, tetragonal and orthorhombic Fe^＋ centers in alkali halides MX （M= Li, Na; X = F, CI） are calculated from second-order perturbation formulas of g factors based on cluster approach for 3d^7 ions in three symmetries. From calculations, the g factors of these Fe^＋ centers in MX crystals are reasonably explained and the defect structural data for the tetragonal and orthorhombic Fe^＋ centers are estimated. The results are discussed.

关键词： crystal- and ligand-field theory electron paramagnetic resonance defect structure

Sequence framework of two different kinds of margins and their response to tectonic activity during the Middle-Late Triassic,Ordos Basin

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Science China Earth Sciences 2007年第Z2期50卷 203-216页

作者： YANG MingHui liu ChiYang zheng MengLin LAN ChaoLi TANG xuan Key Laboratory for Hydrocarbon Accumulation of Education Ministry in China University of Petroleum Basin and Reservoir Research CenterChina University of PetroleumBeijing 102249China State Key Laboratory of Continental Dynamics(Northwest University) Xi'an710069China Exploration&Production Research Institute SINOPECBeijing 100083China School of Engineering of Oil&Gas China University of PetroleumBeijing 102249China School of Energy China University of GeosciencesBeijing 100083China

Two kinds of margin respectively occur in the Ordos Basin during the Middle-Late Triassic(Yanchang Age),one is foreland margin developed under the background of flexural subsidence by thrusting intensively in the southwest margin,and the other is intracratonic basin margin by stable subsidence in northern and central parts of the *** Middle-Late Triassic Yanchang Formation can be divided into four regional third-order sequences,which are separated by gentle angular unconformity or regional erosion surface,made up of lowstand system tract(LST),expanding system tract(EST)and highstand system tract(HST)from lower to upper within a *** there are distinct differences of the sequence framework between the southwest margin and northern and central parts of the *** southwest margin develops heavy conglomerate layer and unconformity as a result of orogeny by thrusting,and the intracratonic basin margin by stable subsidence in the northern and central parts grows aggradational sandstone,conglomerate in fluvio-delta system and parallel *** depositional framework of southwest margin reflects the tectonic evolution from flexural subsidence by thrusting to rebounded *** formation of sequence boundary is related to the resilient uplift and *** sequence stratigraphic framework and depositional system tract configuration in the foreland basin are controlled by structural activity of the fold and thrust belt,and the sequence succession reflects episodic thrusting of the Middle-Late Triassic toward the foreland *** sequence evolution in northern and central parts reflects the depositional succession of fluvio-delta system under intracratonic background,composed of coarse-grained sediment in braided channel deposit at the lower,meandering channel deposit in the middle and fine-grained sediment in the flood plain at the upper,dominated by lake level *** the deposit of the LST in the intracraton basin,accommodation spa

关键词： sequence architecture tectonic response basement structure the Middle-Late Triassic(Yanchang Age) Ordos Basin

An Isogeometric Cloth Simulation Based on Fast Projection Method

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Computer Modeling in Engineering & Sciences 2023年第3期134卷 1837-1853页

作者： xuan Peng Chao zheng Department of Mechanical Engineering Suzhou University of Science and TechnologySuzhou215009China Simshow High Technology Co. Ltd.Chengdu610042China Department of Mechanical and Industrial Engineering The University of IowaIowa CityIA 52242-1527USA

A novel continuum-based fast projection scheme is proposed for cloth *** geometry is described by NURBS,and the dynamic response is modeled by a displacement-only Kirchhoff-Love shell element formulated directly on NURBS *** fast projection method,which solves strain limiting as a constrained Lagrange problem,is extended to the continuum *** examples are studied to demonstrate the performance of the current *** proposed approach can be applied to grids of arbitrary topology and can eliminate unrealistic over-stretching efficiently if compared to spring-based methodologies.

关键词： Cloth simulation isogeometric analysis strain limiting fast projection