检索结果-南通市图书馆

Journal of Hydrodynamics 2022年第2期34卷 299-307页

作者： xiu-xuan Wang Jia-zhong Qian Lei Ma Qian-kun Luo Guan-qun Zhou School of Resources and Environmental Engineering Hefei University of TechnologyHefei230009China

The groundwater flow in natural aquifers can change from the Darcy flow to the non-Darcian flow due to a variety of causes,such as the increase of the Reynolds number in the highly permeable media or the decrease of the hydraulic gradient below a threshold in the low-permeability media,while the representative flow regime cannot be reliably determined using the traditional *** address this challenge,this paper proposes a new term called the equivalent hydraulic gradient(EHG)by generalizing the differential form of the Darcy’s law using a spatial integral of the upstream hydraulic *** nonlocal spatial variation of the hydraulic head difference between upstream and downstream zones is assumed to be the potential cause of the transition of the groundwater flow *** assumption is analogous to the common assumption used for quantifying the anomalous pollutant transport in the geological *** of this idea show that the EHG concept could distinguish three main flow regimes,namely the Super-Darcy flow,the Darcy flow,and the Sub-Darcy flow,although the Super-Darcy flow regime is rarely observed in the laboratory column flow *** of this study therefore shed lights on the interpretation of the fundamental dynamics of the groundwater moving in various heterogeneous aquifers,and may lead to the rebuilding of the hydrodynamics of the surface water,the groundwater,and the soil.

关键词： Hydraulic head distribution spatially non-local effect flow regime Forchheimer number Reynolds number

Simulation of denitrification in groundwater from Chaohu Lake Catchment,China

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Water Science and Engineering 2018年第2期11卷 114-119页

作者： Jia-zhong Qian xiu-xuan Wang Lei Ma Long-ping Wang Jian-kui Liu Zhang-xian Yang School of Resources and Environmental Engineering Hefei University of TechnologyHefei 230009China Anhui Institute of Geo-Environment Monitoring Hefei 230009China

The eutrophication of Chaohu Lake in China is mainly attributed to nitrate inflow from non-point sources in the lake catchment. In this study,biological nitrate reduction from groundwater in the Chaohu Lake Catchment was investigated under laboratory conditions in a continuous upflow reactor. Sodium acetate served as the carbon source and electron donor. Results showed that a carbon-to-nitrogen(C/N) molar ratio of 3:1 and hydraulic retention time(HRT) of 8 d could achieve the most rapid nitrate nitrogen(NO_3^--N) depletion(from 100 mg/L to 1 mg/L within120 h). This rate was confirmed when field groundwater was tested in the reactor, in which a NO_3^--N removal rate of 97.71% was achieved(from60.35 mg/L to 1.38 mg/L within 120 h). Different levels of the initial NO_3^--N concentration(30, 50, 70, and 100 mg/L) showed observable influence on the denitrification rates, with an overall average NO_3^--N removal efficiency of 98.25% at 120 h. Nitrite nitrogen(NO_2^--N)accumulated in the initial 12 h, and then kept decreasing, until it reached 0.0254 mg/L at 120 h. Compared with the initial value, there was a slight accumulation of 0.04 mg/L for the ammonia nitrogen(NH4-N) concentration in the effluent, which is, however, less than the limit *** results can provide a reference for evaluating performance of denitrification in situ.

关键词： Chaohu Lake Catchment Denitrification Eutrophication Nitrate Wetland

Research on Fault Prediction and Health Management(PHM) Based on Data-driven Industrial Robot

在线全文

学校读者我要写书评

暂无评论

Research on Fault Prediction and Health Management(PHM) Base...

作者： xuan xiu Zhanqi Zhong Lei Wu Wuhan University of Technology Computer Integrated Manufacturing System Key Lab of Guangdong Province

Industrial robots play an important role in industrial automation due to their stability, flexibility and excellent production efficiency. More and more companies choose industrial robots to replace manual operations in specific fields. However, as the number and use time of industrial robots continue to increase, the loss rate also increases, and equipment failure in important production occasions will bring unpredictable economic losses and safety problems. Therefore, it has high research value for fault prediction and health management(PHM) of industrial robots.

关键词： data driven industrial robot PHM clustering

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

编辑传播的信息内阻与消除

编辑之友 2020年第4期 84-87页

作者：禤胜修广州工商学院基础教学部广东佛山528137

从信息传播的角度,论述了编辑传播信息内阻的表现及其消除的方法。编辑传播的信息内阻,有文本本身的文字、语法、修辞、逻辑错误所致的误阻,因编排处理不当而造成传播信息序列的阻断或转移而形成的信息隔阻,以及传播的信息缺乏明晰度而... 详细信息

从信息传播的角度,论述了编辑传播信息内阻的表现及其消除的方法。编辑传播的信息内阻,有文本本身的文字、语法、修辞、逻辑错误所致的误阻,因编排处理不当而造成传播信息序列的阻断或转移而形成的信息隔阻,以及传播的信息缺乏明晰度而造成的晦阻。信息内阻的消除有赖于编辑的认真加工、严格校对和合理编排。

关键词：编辑传播信息内阻编辑加工校对编排

在线全文

学校读者我要写书评

暂无评论

冷凝集素增高致双侧睾丸炎一例报道

中国全科医学 2013年第36期16卷 4340-4341页

作者：达选秀甘肃省兰州市皋兰县人民医院检验科 730200

冷凝集素综合征是由于反应性自身红细胞凝集及冷诱导因素导致慢性溶血性贫血和微循环栓塞为特征的一组疾病,是免疫球蛋白M(IgM)抗体引起的自身免疫性疾病,严重时可有溶血性贫血或血红蛋白尿,发生急性血管内溶血者少见。现将我院收治的1... 详细信息

冷凝集素综合征是由于反应性自身红细胞凝集及冷诱导因素导致慢性溶血性贫血和微循环栓塞为特征的一组疾病,是免疫球蛋白M(IgM)抗体引起的自身免疫性疾病,严重时可有溶血性贫血或血红蛋白尿,发生急性血管内溶血者少见。现将我院收治的1例冷凝集素增高引起急性血管内溶血致双侧睾丸炎患者报道如下。

关键词：贫血,溶血性,自身免疫性睾丸炎病例报告

在线全文

学校读者我要写书评

暂无评论

液压支架立柱、千斤顶用新型密封件的研究

煤矿机械 2001年第1期22卷 15-16页

作者：李秀轩煤科总院太原分院山西太原030006

介绍了新型聚胺脂密封件的研究开发和使用过程 ,并与进口同类密封件进行对比 ,有一定的实用价值。

关键词：液压支架聚胺脂密封件千斤顶

经济波动与产业结构合理化的相互作用关系研究

在线全文

学校读者我要写书评

暂无评论

经济问题 2019年第6期 55-64页

作者：张明任烜秀山西财经大学经济学院山西太原030006

对于产业结构合理化和经济波动的关系,国内学者们多是从实证角度研究,发现产业结构合理化对经济波动有较弱的抑制作用,这一结论需要理论论证并深入扩展。首先从理论上论证二者关系可知,一是产业结构合理化本身不能引起经济的波动,但它... 详细信息

对于产业结构合理化和经济波动的关系,国内学者们多是从实证角度研究,发现产业结构合理化对经济波动有较弱的抑制作用,这一结论需要理论论证并深入扩展。首先从理论上论证二者关系可知,一是产业结构合理化本身不能引起经济的波动,但它却影响经济波动的幅度。当经济受到负向冲击时,产业结构合理化能够抑制经济波动的幅度;当经济受到正向冲击时,产业结构合理化能够加剧经济波动的幅度,而不是学界普遍认为的抑制经济波动。二是经济波动对产业结构合理化程度的提高作用不确定。其次通过格兰杰因果检验,状态空间嵌套门限回归模型从实证的角度验证了结论的正确性。最后提出相关政策建议。

关键词：产业结构合理化经济波动要素配置

在线全文

学校读者我要写书评

暂无评论

新型有机太阳能光伏薄膜的制备

西北农林科技大学学报（自然科学版） 2013年第10期41卷 228-234页

作者：孙秀轩郭康权西北农林科技大学机械与电子工程学院陕西杨凌712100

【目的】开发有机太阳能光伏薄膜,弥补传统无机太阳能电池的不足。【方法】利用Suzuki偶联方法,合成了以3,4-乙撑二氧噻吩(EDOT)和异靛蓝(Isoindigo)单元为基础的聚异靛-乙撑二氧噻吩P(iI-EDOT),并制备正型有机太阳能电池,通过热分析仪... 详细信息

【目的】开发有机太阳能光伏薄膜,弥补传统无机太阳能电池的不足。【方法】利用Suzuki偶联方法,合成了以3,4-乙撑二氧噻吩(EDOT)和异靛蓝(Isoindigo)单元为基础的聚异靛-乙撑二氧噻吩P(iI-EDOT),并制备正型有机太阳能电池,通过热分析仪、紫外-可见光分光光度计和电化学工作站,对其热稳定性、紫外吸收和电化学性能进行表征,并对其光伏性能进行测试。【结果】合成的新型材料P(iI-EDOT)具有很好的热稳定性及合适的最高已占轨道能级(EHOMO)和最低未占轨道能级(ELUMO);光伏性能测试表明,基于P(iI-EDOT)制备的有机太阳能电池的开路电压(Voc)为0.45V,短路电流密度(Jsc)为2.80mA/cm2,填充系数(FF)为28%,能量转化效率(PCE)为0.35%。【结论】新合成的导电高分子聚合物P(iI-EDOT)具有一定的光伏性能,还应引进改善物质溶解性的基团,以提高其能量转换效率。

关键词：有机光伏薄膜太阳能电池 3,4-乙撑二氧噻吩聚异靛-乙撑二氧噻吩

CD147 contributes to SARS-CoV-2-induced pulmonary fibrosis

在线全文

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Therapy 2022年第12期7卷 4422-4434页

作者： Jiao Wu Liang Chen Chuan Qin Fei Huo Xue Liang Xu Yang Kui Zhang Peng Lin Jiangning Liu Zhuan Feng Jiansheng Zhou Zhuo Pei Yatao Wang xiu-xuan Sun Ke Wang Jiejie Geng Zhaohui Zheng Xianghui Fu Man Liu Qingyi Wang Zheng Zhang Huijie Bian Ping Zhu Zhi-Nan Chen Department of Cell Biology of National Translational Science Center for Molecular Medicine and Department of Clinical Immunology of Xijing Hospital Fourth Military Medical UniversityXi’an710032China Shanghai Engineering Research Center of Organ Repair School of MedicineShanghai UniversityShanghai200444China Institute of Laboratory Animals Science Chinese Academy of Medical SciencesBeijing100071China

COVID‐19 patients can develop clinical and histopathological features associated with fibrosis,but the pathogenesis of fibrosis remains poorly ***147 has been identified as a universal receptor for SARS-CoV-2 and its variants,which could initiate COVID-19-related cytokine ***,we systemically analyzed lung pathogenesis in SARS-CoV-2-and its delta variant-infected humanized CD147 transgenic *** and Transmission Electron Microscopy revealed inflammation,fibroblast expansion and pronounced fibrotic remodeling in SARS-CoV-2-infected ***,RNA-sequencing identified a set of fibrosis signature ***,we identified CD147 as a crucial regulator for fibroblast activation induced by *** found conditional knockout of CD147 in fibroblast suppressed activation of fibroblasts,decreasing susceptibility to bleomycin-induced pulmonary ***,a CD147 antibody,was able to inhibit the accumulation of activated fibroblasts and the production of ECM proteins,thus alleviating the progression of pulmonary fibrosis caused by *** conclusion,we demonstrated that CD147 contributed to SARS-CoV-2-triggered progressive pulmonary fibrosis and identified CD147 as a potential therapeutic target for treating patients with post-COVID-19 pulmonary fibrosis.

关键词： CD147 inflammation fibrosis

PDGFA-associated protein 1 is a novel target of c-Myc and contributes to colorectal cancer initiation and progression

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cancer Communications 2022年第8期42卷 750-767页

作者： Hong-Yong Cui Wei Wei Mei-Rui Qian Ruo-Fei Tian Xin Fu Hong-Wei Li Gang Nan Ting Yang Peng Lin Xi Chen Yu-Meng ZhuBin Wang xiu-xuan Sun Jian-Hua Dou Jian-Li Jiang Ling Li Shi-Jie Wang Zhi-Nan Chen National Translational Science Center for Molecular Medicine&Department of Cell Biology Fourth Military Medical UniversityXi’anShaanxi 710032P.R.China State Key Laboratory of Cancer Biology and National Clinical Research Center for Digestive Diseases Xijing Hospital of Digestive DiseasesFourth Military Medical UniversityXi’anShaanxi 710032P.R.China Department of Clinical Medicine Medical College of Yan’an UniversityYan’anShaanxi 716000P.R.China Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education College of Chemistry and Materials ScienceNorthwest UniversityXi’anShaanxi 710127P.R.China

Background:The mechanism underlying colorectal cancer(CRC)initiation and progression remains elusive,and overall survival is far from *** studies have shown that PDGFA-associated protein 1(PDAP1)is upregulated in several cancers including ***,we aimed to identify the cause and consequence of PDAP1 dysregulation in CRC and evaluate its role as a potential therapeutic ***:Multi-omics data analysis was performed to identify potential key players in CRC initiation and ***(IHC)staining was applied to determine the expression pattern of PDAP1 in CRC ***1 conditional knockout mice were used to establish colitis and CRC mouse *** sequencing,a phosphoprotein antibody array,western blotting,histological analysis,5-bromo-2′-deoxyuridine(BrdU)incorporation assay,and interactome analysis were applied to identify the underlying mechanisms of PDAP1.A human patient-derived xenograft(PDX)model was used to assess the potential of PDAP1 as a therapeutic ***:PDAP1 was identified as a potential key player in CRC development using multi-omics data ***1 was overexpressed in CRC cells and correlated with reduced overall *** investigation showed that PDAP1 was critical for the regulation of cell proliferation,migration,invasion,and ***,depletion of Pdap1in intestinal epithelial cells impaired mucosal restitution in dextran sulfate sodium salt-induced colitis and inhibited tumor initiation and growth in colitis-associated *** studies showed that c-Myc directly transactivated PDAP1,which contributed to the high PDAP1 expression in CRC ***1 interacted with the juxtamembrane domain of epidermal growth factor receptor(EGFR)and facilitated EGFRmitogen-activated protein kinase(MAPK)signaling activation,which resulted in FOS-related antigen 1(FRA-1)expression,thereby facilitating CRC progres***,silencing of PDAP1 could hinder the

关键词： carcinogenesis colorectal cancer FRA-1 PDAP1 c-Myc