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Time Dependence of Entropy Flux and Entropy Production of a Dissipative Dynamical System Driven by Non-Gaussian Noise

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Communications in Theoretical Physics 2008年第6期49卷 1561-1566页

作者： GUO Yong-Feng xu Wei li dong-Xi XIE Wen-Xian Department of Applied Mathematics Northwestern Polytechnical University Xi＇an 710072 China

A stochastic dissipative dynamical system driven by non-Gaussian noise is investigated. A general approximate Fokker-Planck equation of the system is derived through a path-integral approach. Based on the definition of Shannon＇s information entropy, the exact time dependence of entropy flux and entropy production of the system is calculated both in the absence and in the presence of non-equilibrium constraint. The present calculation can be used to interpret the interplay of the dissipative constant and non-Gaussian noise on the entropy flux and entropy production.

关键词： information entropy entropy flux and entropy production non-Gaussian noise Fokker-Planck equation

Quantitative real-time RT-PCR detection for CEA, CK20 and CK19 mRNA in peripheral blood of colorectal cancer patients

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2006年第6期7卷 445-451页

作者： xu dong li xu-fen ZHENG Shu JIANG Wen-zhi Cancer Institute the Second Affiliated Hospital School of Medicine Zhejiang University Hangzhou 310009 China

This study is aimed at establishing a sensitive approach to detect disseminated tumor cells in peripheral blood and evaluate its clinical significance. A total of 198 blood samples including 168 from colorectal carcinoma (CRC) patients and 30 from healthy volunteers were examined by quantitative real-time reverse transcription-polymerase chain reaction (RT-PCR) to evaluate the expression of carcinoembryonic antigen (CEA), cytokeratin 20 (CK20) and cytokeratin 19 (CK19) mRNA. CEA mRNA was detected in 35.8% of patients and 3.3% of controls, CK20 mRNA in 28.3% of patients and 6.7% of controls, and CK19 mRNA in 41.9% of patients and 3.3% of controls. CEA and CK20 mRNA positive ratio increased with the advancing Dukes stages, but there was no significant difference in positive ratio between any two stages (P>0.05). Also, relatively high positive ratio of CEA, CK20 and CK19 mRNA expression was observed in some CRC patients with earlier Dukes stages. A higher positive ratio was obtained when two or three detection markers were combined compared to a single marker. Our study indicates that quanti-tative real-time RT-PCR detection for CEA, CK20 and CK19 mRNA in peripheral blood is a valuable tool for monitoring early stage dissemination of CRC cells in blood circulation.

关键词： Colorectal carcinoma Real-time RT-PCR CEA mRNA CK20 mRNA CK19 mRNA

OSCILLATION AMPliTUDE OF THE FREE END OF A FLEXIBLY MOUNTED RIGID CYliNDER IN TRIANGLE ARRANGEMENT

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Journal of Hydrodynamics 1998年第3期10卷 101-110页

作者： xu, Youheng dong, liyun Huang, dongqun Fudan Univ Shanghai China

Oscillation amplitude of the free end of a group of the three cylinders was studied. The results of three cylinder arrangement were compared with those of two cylinders in tandem/side-by-side arrangement under the same condition. The experimental results show that the rear cylinder of the three cylinders is affected more seriously than that of two cylinders in contrast arrangement. The main direction of oscillation is changed. The transversal oscillation is stronger than the longitudinal oscillation in the three cylinder arrangement. The transversal oscillation is much weaker than the longitudinal oscillation in the two cylinders arrangement. The large transversal oscillations are attained for the rear cylinder in the third arrangement (two cylinders in tandem arrangement with a side cylinder) at S/D=2.5 and 3.0.

关键词： Cylinders (containers) Flow measurement Oscillations Stability Water wave effects

Remarkably enhanced dielectric stability and energy storage properties in BNT–BST relaxor ceramics by A-site defect engineering for pulsed power applications

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Journal of Advanced Ceramics 2022年第2期11卷 283-294页

作者： Zhipeng li dong-xu li Zong-Yang SHEN Xiaojun ZENG Fusheng SONG Wenqin LUO Xingcai WANG Zhumei WANG Yueming li Energy Storage and Conversion Ceramic Materials Engineering Laboratory of Jiangxi Province China National Light Industry Key Laboratory of Functional Ceramic MaterialsSchool of Materials Science and EngineeringJingdezhen Ceramic UniversityJingdezhen 333403China State Key Laboratory of Advanced Technology for Materials Synthesis and Processing School of Materials Science and EngineeringWuhan University of TechnologyWuhan 430070China Chengdu Hongke Electronic Technology Co. Ltd.Chengdu 610000China

Lead-free bulk ceramics for advanced pulsed power capacitors show relatively low recoverable energy storage density(Wrec)especially at low electric field *** address this challenge,we propose an A-site defect engineering to optimize the electric polarization behavior by disrupting the orderly arrangement of A-site ions,in which Ba_(0.105)Na_(0.325)Sr_(0.245−1.5x)□_(0.5x)Bi_(0.325)+xTiO_(3)(BNS_(0.245−1.5x)□_(0.5x)B_(0.325+x)T,x=0,0.02,0.04,0.06,and 0.08)lead-free ceramics are selected as the *** BNS_(0.245−1.5x)□_(0.5x)B_(0.325+x)T ceramics are prepared by using pressureless solid-state sintering and achieve large W_(rec)(1.8 J/cm^(3))at a low electric field(@110 kV/cm)when x=*** value of 1.8 J/cm3 is super high as compared to all other W_(rec) in lead-free bulk ceramics under a relatively low electric field(lity.

关键词： relaxor ferroelectrics energy storage ceramics ceramic capacitor Bi_(0.5)Na_(0.5)TiO_(3)(BNT) defect engine

Studies on BN rats model to determine the potential allergenicity of proteins from genetically modified foods

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World Journal of Gastroenterology 2005年第34期11卷 5381-5384页

作者： xu-dong Jia Ning li Yong-Ning Wu Xiao-Guang Yang National Institute for Nutrition and Food Safety Chinese Center for Disease Control and Prevention 29 Nanwei Road Beijing 100050China

AIM： To develop a Brown Norway （BN） rat model to determine the potential allergenicity of novel proteins in genetically modified food. METHODS： The allergenicity of different proteins were compared, including ovalbumin （OVA）, a potent respiratory and food allergen, bovine serum albumin （BSA）, a protein that is considered to have a lesser allergenic potential, and potato acid phosphatase （PAP）, a non-allergenic protein when administered to BN rats via different routes of exposure （intraperitoneally or by gavage）. IgG and IgE antibody responses were determined by EliSA and PEA, respectively. An immunoassay kit was used to determine the plasma histamine level. In addition, possible systemic effect of allergens was investigated by monitoring blood pressure. RESULTS： OVA provoked very vigorous protein-specific IgG and IgE responses, low grade protein-specific IgG and IgE responses were elicited by BSA, while by neither route did PAP elicit anything. In either routes of exposure, plasma histamine level in BN rats sensitized with OVA was higher than that of BSA or PAP. In addition, an oral challenge with BSA and PAP did not induce any effect on blood pressure, while a temporary drop in systolic blood pressure in few animals of each routes of exposure was found by an oral challenge with OVA. CONCLUSION： BN rat model might be a useful and predictive animal model to study the potential allergenicity of novel food proteins.

关键词： Animal model Food protein Allergenicity

Maternal sleep deprivation disrupts glutamate metabolism in offspring rats

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Zoological Research 2024年第6期45卷 1221-1231页

作者： Wen-Ting He dong-xu li Jin-Hua Fan Zheng-Yu Yao Yu-Peng Cun Zhi-Fang dong Growth Developmentand Mental Health of Children and Adolescence CenterPediatric Research InstituteMinistry of Education Key Laboratory of Child Development and DisordersNational Clinical Research Center for Child Health and DisordersChongqing Key Laboratory of Child Neurodevelopment and Cognitive DisordersChildren's Hospital of Chongqing Medical UniversityChongqing 400014China

Maternal sleep deprivation(MSD)has emerged as a significant public health concern,yet its effects on offspring metabolism remain poorly *** study investigated the metabolomic implications of MSD on offspring cognitive development,with a particular focus on alterations in glutamate *** rats were subjected to sleep deprivation during late *** and brain samples from their offspring were collected at different postnatal days(P1,P7,P14,and P56)and analyzed using untargeted metabolomics with liquid chromatography-mass *** analysis revealed significant differences in various amino acids,including L-glutamate,L-phenylalanine,L-tyrosine,and L-tryptophan,which are crucial for cognitive *** differential analysis and partial least squares discriminant analysis(sPLS-DA)demonstrated a gradual reduction in these metabolic differences in the brain as the offspring underwent growth and *** pathway analysis revealed differential regulation of several pathways,including alanine,aspartate,and glutamate metabolism,glutathione metabolism,arginine biosynthesis,aminoacyl-tRNA biosynthesis,histidine metabolism,and taurine and hypotaurine metabolism,at different developmental *** and Spearman analyses indicated that the observed changes in metabolites in MSD progeny may be related to various gut microbes,Ruminococcus_1,Ruminococcaceae_UCG-005,and Eubacterium_coprostanoligenes_*** assays further demonstrated developmental changes in the L-glutamate metabolic ***,these findings suggest that MSD not only affects maternal wellbeing but also has enduring metabolic consequences for offspring,particularly impacting pathways linked to cognitive *** highlights the importance of addressing maternal sleep health to mitigate potential long-term consequences for offspring.

关键词： Maternal sleep deprivation Glutamate metabolism Metabolomics Cognitive development Offspring

Preliminary Systematic Study of the Temperature Effect on the K—Cs—Sb Photocathode Performance Based on the K and Cs Co-Evaporation

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Chinese Physics Letters 2020年第1期37卷 6-9页

作者： xu-dong li Zeng-Gong Jiang Qiang Gu Ming-Hua Zhao li Guo Shanghai Advanced Research Institute Chinese Academy of SciencesShanghai 201210 Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800

It is very important to increase the quantum efficiency(QE)and prolong the lifetime of the photocathode in a variety of *** have succeeded in preparing a high QE cesium potassium antimonide(K-Cs-Sb)photocathode by K and Cs co-evaporation in the photocathode preparation *** order to better understand the effect of the substrate(photocathode)temperature on the photocathode performance,the photocathode preparation,photocathode performance degradation,photocathode performance recovery and photocathode removal are studied in detail.

关键词： preparing preparation lifetime

Mechanical characteristics and reservoir stimulation mechanisms of the Gulong shale oil reservoirs, the northern Songliao Basin

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Petroleum Science 2024年第3期21卷 2023-2036页

作者： Si-Wei Meng Jia-Ping Tao Tian-Jiao li dong-xu li Su-ling Wang liu Yang Xin liu li-Hao liang He liu PetroChina Research Institute of Petroleum Exploration Development Beijing100083China National Key Laboratory of Continental Shale Oil Daqing 163002HeilongjiangChina Dalian University of Technology Dalian116024LiaoningChina PetroChina Daqing Oilfield Co.Ltd. Daqing163002HeilongjiangChina Northeast Petroleum University Daqing163002HeilongjiangChina China University of Mining and Technology(Beijing) Beijing100083China

Shale oil of the Qingshankou Formation of the Gulong Sag,the northern Songliao Basin,represents the first attempt at large-scale development of pure-shale-type shale oil in *** integrating the multiscale refined reservoir characterization with macro-micro-scale mechanical testing,it is clarified that the Gulong shale is characterized by high clay mineral content,high rock plasticity,highly-developed bedding,and prominent mechanical anisotropy.A three-dimensional(3D)fracture propagation model of hydraulic fracturing was built for the Gulong shale,which fully captures the hydraulic fracture distribution pattern affected by the high bedding density,in-situ stress,and fracturing treatment *** research showed that due to influences of bedding,hydraulic fracturing in the Gulong shale forms a complex fracture morphology featuring the main fracture with multiple perpendicular branches that have different lengths(like the outdoor directional TV antenna);however,the vertical propagation of fractures is inhibited,and the fracture height is commonly less than 10 *** limited stimulated reservoir volume(SRV)is the main problem facing the fracturing stimulation of the Gulong shale *** density has vital effects on fracture morphology,so case-specific fracturing designs shall be developed for shale intervals with different bedding development *** reservoirs with welldeveloped bedding,it is suggested to properly increase the perforation cluster spacing and raise the volume and proportions of viscous fluids of the pad,so as to effectively promote vertical fracture propagation and improve reservoir stimulation *** study integrates multi-scale fine reservoir characterization and macro-micro-scale mechanical testing,as well as the construction and numerical simulation of hydraulic fracturing models for high-density layered shale reservoirs,providing a new approach and methodological framework for the fracturing research of high-density layer

关键词： Shale oil Hydraulic fracturing High bedding density Fracture propagation model

Optimal proportioning of iron ore in sintering process based on improved multi-objective beluga whale optimisation algorithm

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Journal of Iron and Steel Research International 2024年第7期31卷 1597-1609页

作者： Zong-ping li xu-dong li xue-tong Yan Wu Wen Xiao-xin Zeng Rong-jia Zhu Ya-hui Wang ling-zhi Yi Zhongye Changtian International Engineering Co. Ltd.Changsha 410205HunanChina College of Automation and Electronic Information Xiangtan UniversityXiangtan 411105HunanChina College of Electrical and Information Engineering Hunan UniversityChangsha 410082HunanChina

Proportioning is an important part of sintering,as it affects the cost of sintering and the quality of sintered *** address the problems posed by the complex raw material information and numerous constraints in the sintering process,a multi-objective optimisation model for sintering proportioning was established,which takes the proportioning cost and TFe as the optimisation ***,an improved multi-objective beluga whale optimisation(IMOBWO)algorithm was proposed to solve the nonlinear,multi-constrained multi-objective optimisation *** algorithm uses the con-strained non-dominance criterion to deal with the constraint problem in the ***,the algorithm employs an opposite learning strategy and a population guidance mechanism based on angular competition and two-population competition strategy to enhance convergence and population *** actual proportioning of a steel plant indicates that the IMOBWO algorithm applied to the ore proportioning process has good convergence and obtains the uniformly distributed Pareto ***,compared with the actual proportioning scheme,the proportioning cost is reduced by 4.3361¥/t,and the TFe content in the mixture is increased by 0.0367%in the optimal compromise ***,the proposed method effectively balances the cost and total iron,facilitating the comprehensive utilisation of sintered iron ore resources while ensuring quality assurance.

关键词： Sintering process Proportioning Iron ore Multi-objective beluga whale optimisation algorithm Proportioning cost