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Asian Pacific Journal of Tropical Medicine 2012年第11期5卷 906-910页

作者： Wei-Hong Wang Guo-ping He xu-ping xiao Can Gu Hua-Ying Chen Medical College of Hunan Normal University School of Nursing Central South University First Affiliated Hospital Hunan Normal University

Objective:To determine the relationship between the blood serum brain-derived neurotrophic factor（BDNF） level and cognitive function deterioration in patients with obstructive sleep apnea/ hypopnea syndrome（OSAHS）,and to explore the possible mechanism of cognitive impairment. Methods:Twenty-eight male OSAHS patients and 14 normal males（as controls） were enrolled in the *** and the Montreal cognitive assessment（MoCA） were conducted. The blood serum BDNF levels were measured using ***:The OSAHS group had significantly decreased blood serum BDNF levels compared with the control group（t=-10.912, P=0.000）.The blood serum BDNF level of the subjects was significantly positively associated with the MoCA score（r=0.544,P=0.000）,significantly negatively associated with the apneahypopnea index（AHI） and shallow sleep（S1+S2）（AHI:r=-0.607,P=0.000;S1+S2:r =-0.768,P= 0.000）,and significantly positively associated with the lowest SaO2（LSO）,slow wave sleep（S3+S4）, and rapid eye movement sleep（REM）（LSO:r=0.566,P = 0.000;S3+S4:r=0.778,P=0.000;REM: r=0.575,P=0.000）.Conclusions:OSAHS patients have significantly decreased blood serum BDNF levels compared with the *** hypoxia as well as the deprivation of slow wave sleep and REM may lead to the decreased serum BDNF level of OSAHS *** decreased blood serum BDNF level may contribute to the cognitive impairment in OSAHS.

关键词： Obstructive sleep apnea/hypopnea syndrome Cognitive function Brain-derived neurotrophic factor Sleep

Preparation and Characterization ofβ-Cyclodextrin/Poly(acrylic acid)/Permutite Hydrogel Composite for U(Ⅵ)Adsorption

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Chinese Journal of Structural Chemistry 2020年第10期39卷 1795-1806,1742页

作者： ZHANG Zi-Hui ZHANG Wen xu xiao-ping OU Min-Rui College of Chemistry Fuzhou UniversityFuzhou 350116China College of Chemical Engineering Fuzhou UniversityFuzhou 350116China

Uranium in the environment can damage human health and *** is a need for excellent adsorbents to remove U(Ⅵ)from aqueous *** we synthesized a novelβ-cyclodextrin/poly(acrylic acid)/permutite(CAP)hydrogel composite by a simple *** characterizations of the materials were conducted by XRD,FTIR,SEM,EDX,and *** effect of pH value,contact time,initial U(Ⅵ)concentration,and temperature were researched.A pseudo-second-order kinetic model,intra-particle diffusion model,and Langmuir isotherm model were used to describe the U(Ⅵ)adsorption behavior,and the maximum adsorption capacity of U(Ⅵ)was 833.33 mg/g at 25℃.Thermodynamic analysis showed that the adsorption process of U(Ⅵ)was endothermic and ***,the excellent reusability indicated that CAP hydrogel composite could be potentially used as a promising sorbent for the removal of U(Ⅵ)in wastewater.

关键词： β-cyclodextrin acrylic acid hydrogel adsorption U(Ⅵ)

Genome-wide identification and expression analysis of Argonaute gene family from longan embryogenic callus

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Journal of Integrative Agriculture 2021年第8期20卷 2138-2155页

作者： CHEN Rong-zhu SHEN xu ZHANG Shu-ting ZHAO Hua CHEN xiao-hui xu xiao-ping HUO Wen ZHANG Zi-hao LIN Yu-ling LAI Zhong-xiong Institute of Horticultural Biotechnology Fujian Agriculture and Forestry UniversityFuzhou 350002P.R.China Department of Pharmacy Zhangzhou Health Vocational CollegeZhangzhou 363000P.R.China

Argonaute(AGO)proteins are the core of the RNA-induced gene silencing complex which regulate a wide variety of processes in plants,from organ development to abiotic stress *** have been identified in many plants,but little is known in longan(Dimocarpus longan Lour.),and how AGO functions in the signaling pathways in plant embryos in response to changing environmental stimuli remains *** the present research,a genome-wide analysis of the AGO gene family members and their roles in somatic embryogenesis(SE),zygotic embryogenesis(ZE),tissue developmental processes,and responses to hormones,light and abiotic stress in longan were *** longan AGO genes were identified genome-wide and divided into four *** were distributed on chromosomes 1,4,8,10,12,13,14,and 15,and had 2–23 *** expression profiling implied that DlAGOs regulated early and middle embryogenesis,as well as developmental processes of seed,flower,and stem in *** addition,the transcript levels of DlAGOs in response to exogenous hormones,light and abiotic stress showed differences in expression *** results provide the useful information for further elucidation of RNAi-mediated gene silencing in longan embryogenic callus(EC).

关键词： Argonaute family longan embryogenesis expression profile hormones stress response

Current status and development of hematopoietic stem cell transplantation in China： a report from Chinese Hematopoietic Stem Cell Transplantation Register Group

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Chinese Medical Journal 2011年第16期124卷 2548-2555页

作者： xu Lan-ping HUANG xiao-jun Peking University Institute of Hematology Peking UniversityPeople's Hospital Beijing 100044 China

Allogeneic hematopoietic stem cell transplantation （alIo-HSCT） has three decades history in China. During these periods, the number of HSCT has been increasing, donor and stem cell sources were expanded, indication of diseases and patients for HSCT extended. Forty-two HSCT units offered their data 1-6 times from July 2007 to June 2010. The annual increase rates were 8.8% to 10.8%. Matched sibling donor is 41%, mismatched related/haploidentical donor is 24%, unrelated volunteer donor is 16%, and umbilical cord blood is 2%. The indications of major disease entities are acute myeloid leukemia （AML, 35%）, acute lymphobastic leukemia （ALL, 25%）, chronic myeloid leukemia （CML, 21%）, and myelodysplastic syndrome （MDS, 8%）. The different opinions on the indication of HSCT were supported by some trials, matched/haploidentical HSCT fit for middle or high risk ALL and AML in first complete remission （CR1）, the international prognosis score system （IPSS） -- middle-II/high risk MDS, CML in advanced stage and so on, when patients have no matched sibling donor. In the Peking University Institute of Hematology, Peking University People＇s Hospital, haploidentical HSCT has received a comparable result to matched simbling donor HSCT and unrelated matched donor HSCT; we suggest haploidentical donor might be a routine alternative donor for high-risk patents who need an urgent HSCT without matched related donor in soecial center.

关键词： hematopoietic stem cell transplantation registration unrelated haploidentical

Allogeneic hematopoietic stem cell transplantation for the treatment of chronic myeloid leukemia in the era of tyrosine kinase inhibitors

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Chinese Medical Journal 2013年第4期126卷 768-774页

作者： xu Lan-ping HUANG xiao-jun People's Hospital and Institute of Hematology Peking University Beijing Key laboratory of Hematopoitic Stem Cell Transplantation Beijing 100044 China

The approval of imatinib in 2001 has changed the landscape of CML management.^-3 With its excellent efficacy in the International Interferon and STI571 （IRIS）, Randomized Study of imatinib has become the standard of care for newly diagnosed patients. This change challenges the previous role of allogeneic hematopoietic stem cell transplantation （allo-HSCT） in CML treatment. However,

关键词： allogeneic hematopoietic stem cell transplantation chronic myeloid leukemia tyrosine kinase inhibitors," imatinib

Prevention of pancreatic leakage after pancreaticoduodenectomy by modified Child pancreaticojejunostomy

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Hepatobiliary & Pancreatic Diseases International 2008年第4期7卷 426-429页

作者： Yang, Yan-Ling xu, xiao-ping Wu, Guo-Qiang Yue, Shu-Qiang Dou, Ke-Feng Fourth Mil Med Univ Xijing Hosp Dept Hepatobiliary Surg Xian 710032 Peoples R China S Med Univ Zhujiang Hosp Dept Gen Surg Guangzhou 510282 Guangdong Peoples R China Gen Hosp Shenyang Mil Area PLA Dept Gen Surg Shenyang 110016 Peoples R China

BACKGROUND: Pancreatic leakage after pancreaticoduodenectomy is associated with a morbidity and mortality. Different techniques have been used to make a safe anastomosis to the left pancreatic remnant. METHODS: We performed 'modified Child pancreatico jejunostomy' for 31 patients, by which end-to-end pancreaticojejunal anastomosis was made with a two-layer polypropylene continuous running suture. RESULTS: In the patients who underwent pancreaticojejunostomy, the average operative time was 14.2 minutes. There was no pancreaticoenterostomy leakage in all patients, and no deaths occurred. CONCLUSIONS: In pancreaticojejunostomy, pancreatic anastomosis is time-saving and free from complications. Thus it is an improvement of pancreaticojejunostomy.

关键词： pancreaticojejunostomy pancreaticoduodenectomy pancreatic leakage

Successful second transplantation from haploidentical donor for graft failure following unrelated cord blood cell transplantation or mismatched related transplantation:2 cases report

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Chinese Medical Journal 2006年第17期119卷 1489-1493页

作者： xu Lan-ping HUANG xiao-jun Institute of Hematology People＇s Hospital Peking UniversityBeijing 100044 China

Cord blood transplantation （CBT） from unrelated donors has increasingly been performed worldwide during the last decade. The immaturity of lymphocytes in cord blood permits HLA-mismatching between donors and recipients and reduces the severity of graft-versus-host disease （GVHD）. However, the relatively small dose of the cord blood nucleated cells is associated with a high frequency of engraftment failure.15 But re-transplantation with stem cells from the original donor is impossible.

关键词： haploidential second transplantation graft failure

A Sensitive Material for Specifically Treating Tetracycline in Water Environment

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Chinese Journal of Structural Chemistry 2021年第5期40卷 646-652,530页

作者： OU Min-Rui ZHANG Zi-Hui WEN Yu-Kai xu xiao-ping YANG Huang-Hao College of Chemical Engineering Fuzhou UniversityFuzhou 350116China College of Chemistry Fuzhou UniversityFuzhou 350116China

There are currently many materials for treating residual antibiotics in the environment, but none of them can specifically remove antibiotics. In addition, these materials are not sensitive enough to low concentrations of antibiotics. Here we show that a sensitive and specific material was developed by the preparation of magnetic Fe_(3)O_(4)-PAMAM-antibody complexes for treating tetracycline. The prepared antibody complexes can specifically treat tetracycline from aqueous solutions and the tetracycline removal ability by adsorption was also investigated. Controlled experiments were carried out with the effects of solution pH, temperature, and initial concentration of the tetracycline. The tetracycline was completely removed within 35 min at room temperature 30 ℃ with the maximum removal rate of almost 100%. Therefore, this material for specifically combining antigen and antibody to treat tetracycline indicated good application prospects for the waste water treatment.

关键词： complex material antibody specificity tetracycline water treatment

Erosion Resistance Behaviours of H13 Steel to Molten ADC12 Alloy

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材料热处理学报 2004年第5期25卷 239-243页

作者： MINYong-an xuLuo-ping WUxiao-chun LILin WANGRong SchoolofmaterialsscienceandEngineering ShanghaiUniversityShanghaiChina

H13 hot work steel samples and surface water vapor oxidized H13 samples were immersed into molten ADC 12 alloy under static resting or dynamic rotating conditions. Weigh-losing method was used to discover the influences of temperature, time and surface conditions on the erosion resistance of H13 steel. The interfaces between the steel and the molten alloy were studied with optical microscopy to compare the different erosion resistance behaviours. The results show that the composite layer outside of the compounds layers changes obviously with increasing temperature, lasting time or sample movement. The better erosion resistance of H13 steel can be endowed with the oxide films, which would gradually decrease along with the dissolve of the films.

关键词：抗腐蚀性氧化薄膜热锻模具钢铝合金

Simultaneous Stabilization for a Family of Plants

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Journal of Mathematical Research and Exposition 2008年第3期28卷 529-534页

作者： LU Yu Feng xu xiao ping Department of Applied Mathematics Dalian University of Technology Liaoning 116024 China

In this paper, we discuss the problem of simultaneous stabilization for plants more than three by using Youla parametrization and give a necessary and sufficient condition for simultaneous stabilization.

关键词： complete nest nest algebra linear system stabilizable.