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New poly-types of LPSO structures in a non-equilibrium Mg_(97)Zn_(1)Y_(1.6)Ca_(0.4)alloy

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China Foundry 2025年第1期22卷 83-89页

作者： Qian-qian Jin Zi-hui Tang Wen-long Xiao Xiu-yu Qu xu-hao Han Lin Mei Xiao-hong Shao Xiu-liang ma School of Biological and Chemical Engineering Guangxi University of Science and TechnologyLiuzhou 545006GuangxiChina Center for the Structure of Advanced matter School of Electronic EngineeringGuangxi University of Science and TechnologyLiuzhou 545006GuangxiChina Shenyang National Laboratory for materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China Bay Area Center for Electron Microscopy Songshan Lake Materials LaboratoryDongguan 523808GuangdongChina

In this study,a comprehensive analysis of microstructural features,morphology,crystal structures,and interface structures of long-period stacking ordered(LPSO)structures in a non-equilibrium Mg_(97)Zn_(1)Y_(16)Ca_(0.4)alloy cast in a steel mold was carried *** addition of Ca element plays an important role in the refinement of LPSO *** result reveals new poly-types including 20H F2F2F4,60R(F2F3F3)_(3),and 66H F2F3F3F2(F6)_(4)featuring a 6-Mg structure,alongside the prevalent 18R and 14H LPSO *** incoherent interface between 20H and the Mg matrix is split into two dislocation arrays,leading to the formation of a segment of 60R_(1).Moreover,the superstructure 116L,designated as(F2)_(18)F4,is formed through the ordered distribution of F4 stacking faults in 18R.

关键词： LPSO structures crystal structure Mg alloys heterogeneous interface

Small extracellular vesicles derived from human induced pluripotent stem cell-differentiated neural progenitor cells mitigate retinal ganglion cell degeneration in a mouse model of optic nerve injury

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Neural Regeneration Research 2025年第2期20卷 587-597页

作者： Tong Li Hui-Min Xing Hai-Dong Qian Qiao Gao Sheng-Lan xu Hua ma Zai-long Chi State Key Laboratory of Ophthalmology Optometry and Visual ScienceEye HospitalWenzhou Medical UniversityWenzhouZhejiang ProvinceChina National Clinical Research Center for Ocular Diseases Eye HospitalWenzhou Medical UniversityWenzhouZhejiang ProvinceChina

Several studies have found that transplantation of neural progenitor cells(NPCs)promotes the survival of injured ***,a poor integration rate and high risk of tumorigenicity after cell transplantation limits their clinical *** extracellular vesicles(sEVs)contain bioactive molecules for neuronal protection and *** studies have shown that stem/progenitor cell-derived sEVs can promote neuronal survival and recovery of neurological function in neurodegenerative eye diseases and other eye *** this study,we intravitreally transplanted sEVs derived from human induced pluripotent stem cells(hiPSCs)and hiPSCs-differentiated NPCs(hiPSC-NPC)in a mouse model of optic nerve *** results show that these intravitreally injected sEVs were ingested by retinal cells,especially those localized in the ganglion cell *** with hiPSC-NPC-derived sEVs mitigated optic nerve crush-induced retinal ganglion cell degeneration,and regulated the retinal microenvironment by inhibiting excessive activation of *** analysis further revealed that hiPSC-NPC derived sEVs transported neuroprotective and anti-inflammatory miRNA cargos to target cells,which had protective effects on RGCs after optic nerve *** findings suggest that sEVs derived from hiPSC-NPC are a promising cell-free therapeutic strategy for optic neuropathy.

关键词： exosome miRNA neural progenitor cell neurodegeneration neuroinflammation neuroprotection optic nerve crush optic neuropathy retinal ganglion cell small extracellular vesicles

Engineering strategies of biomaterial-assisted exosomes for skin wound repair:Latest advances and challenges

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Chinese Chemical Letters 2025年第1期36卷 99-109页

作者： Yang xu Le ma Yang Wang Chunmeng Shi Institute of Rocket Force Medicine State Key Laboratory of Trauma and Chemical PoisoningThird Military Medical University(Army Medical University)Chongqing 400038China

The treatment of skin wounds,especially chronic wounds,remains a critical clinical challenge and places a heavy burden on patients and healthcare *** recent years,the engineering strategy of using biomaterial-assisted exosomes has emerged as a powerful tool for skin *** to treatments such as debridement and regular dressing changes,the design of biomaterial-assisted exosomes not only maintains the bioactivity of exosomes at the wound site but also provides an appropriate microenvironment for the repair of complex tissues,thereby accelerating wound *** review systematically introduces the general characteristics of exosomes and their functions in skin wound healing,highlights recent advances in classification of natural exosomes and engineering methods which enriching their functions in intercellular ***,various emerging and innovative approaches based on biomaterials delivery of exosomes are comprehensively *** review seeks to bring an in-depth understanding of bioactive dressings based on exosomes therapeutic strategies,aiming to facilitate new clinical application value.

关键词： Exosomes Biomaterials Hydrogel Delivery system Wound healing

Effect of rolling schedules on ridging resistance of ultra-thin ferritic stainless steel foil

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Journal of Iron and Steel Research International 2025年第1期32卷 198-214页

作者： Jing-wei Zhao Qing-zhong Xie Li-nan ma Cun-long Zhou Zheng-yi Jiang Xi Liao Xiao-guang ma College of Mechanical and Vehicle Engineering Taiyuan University of TechnologyTaiyuan030024ShanxiChina Engineering Research Center of Advanced Metal Composites Forming Technology and Equipment Ministry of EducationTaiyuan030024ShanxiChina National Key Laboratory of Metal Forming Technology and Heavy Equipment Ministry of Science and TechnologyTaiyuan030024ShanxiChina School of Mechanical Engineering Taiyuan University of Science and TechnologyTaiyuan 030024ShanxiChina School of Mechanical MaterialsBiomedical and Mechatronic EngineeringUniversity of WollongongWollongongNSW2522Australia Shanxi Taigang Stainless Steel Precision Strip Co. Ltd.Taiyuan 030006ShanxiChina

The effect of rolling schedules on the ridging resistance of ultra-thin ferritic stainless steel(FSS)430 foil was evaluated by studying the microstructure and *** results show that specimens processed with three-pass cold rolling under the reductions of 40%,40%and 31%,respectively,exhibit improved ridging resistance owing to the microstructural refinement and the texture structure optimization.A nearly 40%reduction of ridging height can be achieved using the proposed rolling schedule compared to the other two rolling *** addition,the effect of annealing temperature after cold rolling on the ridging resistance of FSS 430 foil is also found to be crucial,and an optimal annealing temperature of 900℃ is obtained for FSS 430 foil with high ridging ***,the improvement in the ridging resistance of FSS 430 foil can be attributed to the reduction in the fraction of{001}and{114}components by optimization of the rolling and annealing processes.

关键词： Ferritic stainless steel foil Ridging Cold rolling Annealing Microstructure Texture

Atomic cerium-doped CuO_(x) catalysts for efficient electrocatalytic CO_(2) reduction to CH_(4)

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Chinese Chemical Letters 2025年第1期36卷 326-331页

作者： Xiangyu Chen Aihao xu Dong Wei Fang Huang Junjie ma Huibing He Jing xu Guangxi Key Laboratory of Petrochemical Resource Processing and Process Intensification Technology School of Chemistry and Chemical EngineeringGuangxi UniversityNanning 530004China State Key Laboratory of Featured Metal materials and Life-cycle Safety for Composite Structures Guangxi UniversityNanning 530004China State Key Laboratory of Green Chemical Engineering and Industrial Catalysis School of Chemical EngineeringEast China University of Science and TechnologyShanghai 200237China

Copper(Cu)is widely used in the electrochemical carbon dioxide reduction reaction(ECO_(2)RR)for efficient methane(CH_(4))***,the morphology and valence of Cu-based catalysts are usually unstable under reaction *** this work,we prepared Ce-doped MOF-199 precursor(Ce/HKUST-1)and further obtained nanoparticle electrocatalyst Ce/CuO_(x)-NPs by cyclic voltammetry(CV)*** Faradic efficiency of methane(FE_(CH_(4)))maintains above 62%within a broad potential window of 350 mV and the maximum FE_(CH_(4))reaches 67.4%with a partial current density of 293 ma/cm^(2)at-1.6 V vs.a reversible hydrogen *** characterization and theoretical calculations revealed that the unique electronic structure and large ionic radius of Cerium(Ce)not only promoted the generation of key intermediate*CO but also lowered energy barrier of the*CO to*CHO *** study provides a novel and efficient catalyst for methane production in ECO_(2)RR and offers profound insights into constructing high performance Cu-based catalysts.

关键词： ECO_(2)RR Cu-based catalyst Structure evolution DFT calculation

When Software Security Meets Large Language Models:A Survey

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IEEE/CAA Journal of Automatica Sinica 2025年第2期12卷 317-334页

作者： Xiaogang Zhu Wei Zhou Qing-long Han Wanlun ma Sheng Wen Yang Xiang IEEE the School of Computer and mathematical Sciences the University of Adelaide the School of Science Computing and Engineering Technologies Swinburne University of Technology

Software security poses substantial risks to our society because software has become part of our life. Numerous techniques have been proposed to resolve or mitigate the impact of software security issues. Among them, software testing and analysis are two of the critical methods, which significantly benefit from the advancements in deep learning technologies. Due to the successful use of deep learning in software security, recently,researchers have explored the potential of using large language models(LLMs) in this area. In this paper, we systematically review the results focusing on LLMs in software security. We analyze the topics of fuzzing, unit test, program repair, bug reproduction, data-driven bug detection, and bug triage. We deconstruct these techniques into several stages and analyze how LLMs can be used in the stages. We also discuss the future directions of using LLMs in software security, including the future directions for the existing use of LLMs and extensions from conventional deep learning research.

关键词： Large language models (LLMs) software analysis software security software testing

Research on the balance optimization algorithm of image recognition accuracy and speed based on autocollimator measurement

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Optoelectronics Letters 2025年第2期21卷 121-128页

作者： LI Renpu ma long CUI Jiwen GUO Junqi Andrei KULIKOV WEN Dandan Chongqing Engineering Research Center of Intelligent Sensing Technology and Microsystem Chongqing University of Post and TelecommunicationsChongqing 400065China School of Instrumentation Science and Engineering Harbin Institute of TechnologyHarbin 150080China Higher School of Engineering and Technology ITMO UniversitySaint Petersburg 197101Russia

The autocollimator is an important device for achieving precise,small-angle,non-contact *** primarily obtains angular parameters of a plane target mirror indirectly by detecting the position of the imaging *** is limited report on the core algorithmic techniques in current commercial products and recent scientific *** paper addresses the performance requirements of coordinate reading accuracy and operational speed in autocollimator image *** proposes a cross-image center recognition scheme based on the Hough transform and another based on Zernike moments and the least squares *** experimental evaluation of the accuracy and speed of both schemes,the optimal image recognition scheme balancing measurement accuracy and speed for the autocollimator is *** these,the center recognition method based on Zernike moments and the least squares method offers higher measurement accuracy and stability,while the Hough transform-based method provides faster measurement speed.

关键词： image optimization recognition

Achievable Rate Analysis and Optimization of Double-RIS Assisted Spatially Correlated MIMO with Statistical CSI

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China Communications 2025年第1期22卷 139-157页

作者： xu Kaizhe Guo Jiajia Zhang Jun Jin Shi ma Shaodan Department of Communications and Networking Xi’an Jiaotong-Liverpool UniversitySuzhou 215123China State Key Laboratory of Internet of Things for Smart City University of MacaoMacao SARChina Jiangsu Key Laboratory of Wireless Communications Nanjing University of Posts and TelecommunicationsNanjing 210003China National Mobile Communications Research Laboratory Southeast UniversityNanjing 210096China State Key Laboratory of Internet of Things for Smart City and the Department of Electrical and Computer Engineering University of MacaoMacao SARChina

Reconfigurable intelligent surface(RIS)is a novel meta-material which can form a smart radio environment by dynamically altering reflection directions of the impinging electromagnetic *** the prior literature,the inter-RIS links which also contribute to the performance of the whole system are usually neglected when multiple RISs are *** this paper we investigate a general double-RIS assisted multiple-input multiple-output(MIMO)wireless communication system under spatially correlated non line-of-sight propagation channels,where the cooperation of the double RISs is also *** design objective is to maximize the achievable ergodic rate based on full statistical channel state information(CSI).Specifically,we firstly present a closedform asymptotic expression for the achievable ergodic rate by utilizing replica method from statistical *** a full statistical CSI-enabled optimal design is proposed which avoids high pilot training overhead compared to instantaneous CSI-enabled *** further reduce the signal processing overhead and lower the complexity for practical realization,a common-phase scheme is proposed to design the double *** results show that the derived asymptotic ergodic rate is quite accurate even for small-sized antenna *** the proposed optimization algorithm can achieve substantial gain at the expense of a low overhead and ***,the cooperative double-RIS assisted MIMO framework is proven to achieve superior ergodic rate performance and high communication reliability under harsh propagation environment.

关键词： common reflection pattern double RISs large system analysis MIMO replica method

Recombinant chitinase-3-like protein 1 alleviates learning and memory impairments via M2 microglia polarization in postoperative cognitive dysfunction mice

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Neural Regeneration Research 2025年第9期20卷 2727-2736页

作者： Yujia Liu xue Han Yan Su Yiming Zhou Minhui xu Jiyan xu Zhengliang ma Xiaoping Gu Tianjiao Xia Department of Anesthesiology Nanjing Drum Tower HospitalAffiliated Hospital of Medical SchoolNanjing UniversityNanjingJiangsu ProvinceChina Medical School Nanjing UniversityNanjingJiangsu ProvinceChina Jiangsu Key Laboratory of Molecular Medicine Nanjing UniversityNanjingJiangsu ProvinceChina State Key Laboratory of Pharmaceutical Biotechnology Nanjing UniversityNanjingJiangsu ProvinceChina Department of Anesthesiology Zhongshan HospitalFudan UniversityShanghaiChina

Postoperative cognitive dysfunction is a seve re complication of the central nervous system that occurs after anesthesia and surgery,and has received attention for its high incidence and effect on the quality of life of *** date,there are no viable treatment options for postoperative cognitive *** identification of postoperative cognitive dysfunction hub genes could provide new research directions and therapeutic targets for future *** identify the signaling mechanisms contributing to postoperative cognitive dysfunction,we first conducted Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analyses of the Gene Expression Omnibus GSE95426 dataset,which consists of mRNAs and long non-coding RNAs differentially expressed in mouse hippocampus3 days after tibial *** dataset was enriched in genes associated with the biological process"regulation of immune cells,"of which Chill was identified as a hub ***,we investigated the contribution of chitinase-3-like protein 1 protein expression changes to postoperative cognitive dysfunction in the mouse model of tibial fractu re *** were intraperitoneally injected with vehicle or recombinant chitinase-3-like protein 124 hours post-surgery,and the injection groups were compared with untreated control mice for learning and memory capacities using the Y-maze and fear conditioning *** addition,protein expression levels of proinflammatory factors(interleukin-1βand inducible nitric oxide synthase),M2-type macrophage markers(CD206 and arginase-1),and cognition-related proteins(brain-derived neurotropic factor and phosphorylated NMDA receptor subunit NR2B)were measured in hippocampus by western *** with recombinant chitinase-3-like protein 1 prevented surgery-induced cognitive impairment,downregulated interleukin-1βand nducible nitric oxide synthase expression,and upregulated CD206,arginase-1,pNR2B,and brain-derived neurotropic factor expr

关键词： Chil1 hippocampus learning and memory M2 microglia neuroinflammation postoperative cognitive dysfunction(POCD) recombinant CHI3L1