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Hybrid Routing by Joint Optimization of Per-Flow Routing and Tag-Based Routing in Software-Defined Networks

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Tsinghua Science and Technology 2018年第4期23卷 440-452页

作者： Gongming Zhao Liusheng Huang Ziqiang Li hongli xu School of Computer Science and Technology University of Science and Technology of China Hefei 230027 China Institute for Advanced Study University of Science and Technology of China Suzhou 215123 China

In recent years, Software-Defined Networks （SDNs） have become a promising technology to improve network utilization. However, limited flow table size and long deployment delays may result in low network performance in large-scale networks and a poor user experience. While a typical solution to this issue is routing aggregation （i.e., wildcard routing）, the aggregation feasibility problem and reduced network performance may be encountered. To address this dilemma, we first design a novel wildcard routing scheme, called the Tag-based Rule Placement Scheme （TRPS）. We then formulate a Hybrid Routing by Joint optimization of Per-flow routing and Tag- based routing （HR-JPT） problem, and prove its NP-hardness. An algorithm with a bounded approximation factor is designed for this problem, and the proposed methods are implemented on a Mininet platform. Extensive simulation results show that our methods are efficient for wildcard/hybrid routing. For example, our proposed tag-based wildcard rule placement scheme can reduce the number of required rules by about 65% on average compared with previous wildcard routing methods. Our proposed hybrid routing algorithm can increase network throughput by about 43% compared with existing hybrid routing solutions.

关键词： Software Defined Networks (SDNs) load balancing per-flow routing tag-based routing flow table sizeconstraint deployment delay constraint

Expression of toll-like receptor 4 and MD-2 gene and protein in Kupffer cells after ischemia-reperfusion in rat liver graft

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World Journal of Gastroenterology 2004年第19期10卷 2890-2893页

作者： YongPeng Jian-PingGong Chang-AnLiu xu-hongli LingGan Shou-BaiLi DepartmentofHepatobiliarySurgery theSecondAffiliatedHospitalofChongqingMedicalUniversityChongqing400010China

AIM: To investigate the expression of toll-like receptor 4(TLR4) and MD-2 gene and protein in Kupffer cells (KCs)and their role in ischemia-reperfusion (IR) injury of ratliver ***: KCs were isolated at 0 (control group), 2, 12,24 h (IR group) following IR in rat liver graft, mRNA expressionof TLR4 and MD-2 was detected by RT-PCR analysis, proteinexpression of TLR4/MD-2 was detected by flow cytometric(FCM) analysis, and tumor necrosis factor-(~ (TNF-(~) levelin supernatant was measured by ELISA. Then isolated KCswere incubated with anti-TLR4 polyclonal antibody (anti-TLR4 group), and TNF-(~ level was measured ***: The mRNA and protein expression of TLR4/MD-2 and the level of TNF-(~ in IR group increased significantlyat 2 h following IR, and reached the maximum at 12 h, andslightly decreased at 24 h, but were still significantly higherthan those in the control group (P

关键词：基因表达受体4 MD-2基因蛋白质枯否氏细胞局部缺血多次灌注液老鼠肝移植抗体

UTILITY OPTIMIZATION SCHEDULING FOR MULTI-POINT VIDEO SURVEILLANCE IN UBIQUITOUS NETWORK

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Journal of Electronics(China) 2013年第1期30卷 1-8页

作者： Zhang Chen Huang Liusheng xu hongli Department of Computer Science and Technology University of Science and Technology of China

Resource allocation is an important problem in ubiquitous network. Most of the existing resource allocation methods considering only wireless networks are not suitable for the ubiquitous network environment, and they will harm the interest of individual users with instable resource requirements. This paper considers the multi-point video surveillance scenarios in a complex network environment with both wired and wireless networks. We introduce the utility estimated by the total costs of an individual network user. The problem is studied through mathematical modeling and we propose an improved problem-specific branch-and-cut algorithm to solve it. The algorithm follows the divide-and-conquer principle and fully considers the duality feature of network selection. The experiment is conducted by simulation through C and Lingo. And it shows that compared with a centralized random allocation scheme and a cost greed allocation scheme, the proposed scheme has better per- formance of reducing the total costs by 13.0% and 30.6% respectively for the user.

关键词： Ubiquitous network Multi-point video surveillance Resource allocation

Construction of a targeting adenoviral vector carrying AFP promoter for expressing EGFP gene in AFP-producing hepatocarcinoma cell

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World Journal of Gastroenterology 2004年第2期10卷 186-189页

作者： Yu-JunShi Jian-PingGong Chang-AnLiu xu-hongli YingMei CanMi Yan-YingHuo DepartmentofGeneralSurgery theSecondCollegeofClinicalMedicineandtheSecondAffiliatedHospitalofChongqingUniversityofMedicalSciencesChongqing400010China DepartmentofPathoiogy BasicMedicalCollegeChongqingUniversityofMedicalSciencesChongqing400016China InstituteforRadiology MilitaryAcademyofMedicalSciencesBeijing100850China

AIM:To construct a recombinant adenoviral vector carrying AFP promoter and EGFP gene for specific expression of EGFP gene in AFP producing hepatocellular carcinoma (HCC) HepG2 ***: Based on the Adeno-X^TM expression system, the human immediate early cytomegalovirus promoter (PCMV IE)was removed from the plasmid, pshuttle,and replaced by a 0.3 kb (α-fetoprotein (AFP) promoter that was synthesized by polymerase chain reaction (PCR).The enhanced green fluorescent protein (EGFP) gene was inserted into the multiclone site (MCS),and then the recombinant adenovirus vector carrying the 0.3kb AFP promoter and EGFP gene was *** of a normal liver cell line (LO2),a hepatocarcinoma cell line (HepG2) and a cervical cancer cell line (HeLa) were transfected with the *** blot and fluorescence microscopy were used to detect the expression of the EGFP gene at mRNA or protein level in three different cell ***:The 0.3kb AFP promoter was synthesized through PCR from the human *** AFP promoter and EGFP gene were directly inserted into the plasmid pshuttle as confirmed by restriction digestion and DNA *** blot showed that EGFP gene was markedly transcribed in HepG2 cells,but only slightly in LO2 and HeLa *** addition,strong green fluorescence was observed in HepG2 cells under a fluorescence microscopy,but fluorescence was very weak in LO2 and HeLa ***:Under control of the 0.3kb human AFP promoter, the recombinant adenovirus vector carrying EGFP gene can be specially expressed in AFP-producing HepG2 cells,Therefore,this adenovirus system can be used as a novel,potent and specific tool for gene-targeting therapy for the AFP positive primary hepatocellular carcinoma,

关键词：肝细胞癌聚合酶链反应 AFP EGFP基因基因序列重组肾病毒受体

Privacy-Preserving Strategyproof Auction Mechanisms for Resource Allocation

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Tsinghua Science and Technology 2017年第2期22卷 119-134页

作者： Yu-E Sun He Huang Xiang-Yang Li Yang Du Miaomiao Tian hongli xu Mingjun Xiao School of Urban Rail Transportation Soochow University School of Computer Science and Technology Soochow University School of Computer Science and Technology University of Science and Technology of China Suzhou Institute for Advanced Study University of Science and Technology of China School of Computer Science and Technology Anhui University

In recent years, auction theory has been extensively studied and many state-of-the-art solutions have been proposed aiming at allocating scarce resources. However, most of these studies assume that the auctioneer is always trustworthy in the sealed-bid auctions, which is not always true in a more realistic scenario. Besides the privacy-preserving issue, the performance guarantee of social efficiency maximization is also crucial for auction mechanism design. In this paper, we study the auction mechanisms that consider the above two aspects. We discuss two multi-unit auction models： the identical multiple-items auction and the distinct multiple-items *** the problem of determining a multi-unit auction mechanism that can maximize its social efficiency is NPhard, we design a series of nearly optimal multi-unit auction mechanisms for the proposed models. We prove that the proposed auction mechanisms are strategyproof. Moreover, we also prove that the privacy of bid value from each bidder can be preserved in the auction mechanisms. To the best of our knowledge, this is the first work on the strategyproof multi-unit auction mechanisms that simultaneously consider privacy preservation and social efficiency maximization. The extensive simulations show that the proposed mechanisms have low computation and communication overheads.

关键词： approximation mechanism multi-unit auction privacy preserving social efficiency strategyproof

Role of NF-kB in multiple organ dysfunction during acute obstructive cholangitis

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World Journal of Gastroenterology 2003年第1期9卷 179-183页

作者： BinTu Jian-PingGong Hu-YiFeng Chuan-XinWu Yu-JunShi xu-hongli YongPeng Chang-AnLiu Sheng-WeiLi DepartmentofGeneralSurgery theSecondCollegeofClinicalMedicine&theSecondAffiliatedHospitalofChongqingUniversity'ofMedicalScience74LinjiangRoadChongqing400010China DepartmentofGeneralSurgery theSecondCollegeofClinicalMedicine&theSecondAffiliatedHospitalofChongqingUniversity'ofMedicalScience74LinjiangRoadChongqing400010China

AIM:To elucidate the role of NF-kB activation in the development of multiple organ dysfunction(MOD)during acute obstructive cholangitis(AOC)in rats. METHODS:Forty-two Wistar rats were divided into three groups:the AOC group,the group of bile duct ligation(BDL group),and the sham operation group(SO group).All the animals in the three groups were killed in the 6th and 48th hour after *** changes of vital organs were observed under light and electron ***-κB activation was determined with Electrophoretic Mobility Shift Assay(EMSA).Arterial blood gas analyses and the serum levels of lactate dehydrogenase(LDH),alanine aminotransferase(ALT),blood urea nitrogen(BUN)and creatinine were *** concentrations of TNF-α and IL-6 in plasma were also measured. RESULTS:The significant changes of histology and ultrastructure of vital organs were observed in AOC group. By contrast,in BDL group,all the features of organs damage were greatly *** of NF-κB activation in various tissues increased in AOC group when compared to other two *** 6 h,the arterial pH in three groups was 7.52±0.01,7.46±0.02,and 7.45±0.02,and the blood pCO_2 was 33.9±0.95 mmHg,38.1±0.89 mmHg,38.9±0.94 mmHg,there was difference in three groups(P<0.05).At 48 h,the blood pH values in three groups was 7.33±0.07, 7.67±0.04,and 7.46±0.03,and blood HCO_3^- was 20.1±1.29 mmol·L^(-1),26.7±1.45 mmol·L^(-1)and 27.4±0.35 mmol·L^(-1),there was also difference in three groups(P<0.05).In AOC group, Levels of LDH,ALT,BUN and creatinine were 16359.9±2278.8 nkat·L^(-1),5796.2±941.9 nkat·L^(-1),55.7±15.3 mg/dl,and 0.72± 0.06 mg/dl,which were higher than in SO group(3739.1± 570.1 nkat·L^(-1),288.4±71.7 nkat·L^(-1),12.5±2.14 mg/dl,and 0.47±0.03 mg/dl)(P<0.05).Levels of plasma TNF-α and IL-6 in AOC at 48 h were 429±56.62 ng·L^(-1)and 562±57 ng·L^(-1), which increased greatly when compared to BDL group (139±16 ng·L^(-1),227±43 ng·L^(-1))and SO group(74±10 ng·L^(-1), 113±19 ng·L^(-

关键词：核因子-κB 急性阻塞性胆管炎多器官功能失调病理机制动物模型

Synthesis of endotoxin receptor CD14 protein in Kupffer cells and its role in alcohol-induced liver disease

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World Journal of Gastroenterology 2003年第3期9卷 622-626页

作者： Li-LiDai Jian-PingGong Guo-QingZuo Chuan-XinWu Yu-JunShi xu-hongli YongPeng WuDeng Sheng-WeiLi chang-AnLiu DepartmentofDigestiveDisease theSecondCollegeofClinicalMedicine&theSecondAffiliatedHospitalofChongqingUniversityofMedicalScience74LinjiangRoadChongqing400010China DepartmentofGeneralSurgery theSecondCollegeofClinicalMedicine&theSecondAffiliatedHospitalofChongqingUniversityofMedicalScience74LinjiangRoadChongqing400010China

AIM: To observe the synthesis of endotoxin receptor CD14 protein and its mRNA expression in Kupffer cells (KCs), and evaluate the role of CD14 in the pathogenesis of liver injury in rats with alcohol-induced liver disease (ALD).METHODS: Twenty-eight Wistar rats were divided into two groups: ethanol-fed group and control group. Ethanol-fed group dextrose instead of ethanol. Two groups were sacrificed at 4 wk and 8 wk, respectively. KCs were isolated and the synthesis of CD14 protein and its mRNA expression in KCs were determined by flow cytometric analysis (FCM)or the reverse transcription polymerase chain reaction (RTPCR) analysis. The levels of plasma endotoxin and alanine transaminase (ALT) were measured by Limulus Amebocyte Lysate assay and standard enzymatic procedures respectively, and the levels of plasma tumor necosis factor (TNF)-α and interleukin (IL)-6 were both determined by ELISA. The liver pathology change was observed under light and electric ***: In ethanol-fed group, the percentages of FITCCD14 positive cells were 76.23 % and 89.42 % at 4 wk and 8 wk, respectively. Compared with control group (4.45 %and 5.38 %), the difference was significant (P＜0.05). The expressions of CD14 mRNA were 7.56±1.02 and 8.74±1.37 at 4 wk and 8 wk, respectively, which were significantly higher compared with the control group (1.77±0.21 and 1.98±0.23)(P＜0.05). Plasma endotoxin levels at 4 wk and 8 wk increased dramatically in ethanol-fed rats (112±15 IU/L and 147±22 IU/L) than those in the control animals (31±12 IU/L and 33±9 IU/L) (P＜0.05). In ethanol-fed rats, the levels of wk, respectively which were significantly higher than those fed rats, there were marked pathological changes including steatosis, cell infiltration and necrosis. No marked pathological changes were seen in control ***: Ethanol administration led to a significantsynthesis of endotoxin receptor CD14 protein and its gene expression in KCs, which maybe result in the pathologica

关键词：内毒素受体 CD14蛋白 Kupffer细胞酒精性肝病肝功能发病机制

多模式交通网络下考虑尾气排放的道路收费研究

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系统工程理论与实践 2016年第9期36卷 2345-2354页

作者：徐薇范名才徐红利南京大学工程管理学院南京210093

随着出行需求和机动车保有量的迅猛增加,城市道路不堪重负,不仅交通拥堵严重,同时大量的尾气排放更造成了严重的空气环境污染问题.本文在传统的道路收费研究中明确加入排放约束或目标,建立了一系列带均衡约束的数学规划双层决策模型,探... 详细信息

随着出行需求和机动车保有量的迅猛增加,城市道路不堪重负,不仅交通拥堵严重,同时大量的尾气排放更造成了严重的空气环境污染问题.本文在传统的道路收费研究中明确加入排放约束或目标,建立了一系列带均衡约束的数学规划双层决策模型,探讨多模式混合交通网络下如何通过经济手段诱导人们选择更环保的出行模式和更合理的出行路径,以同时达到缓解交通拥堵和降低尾气排放的目的.模型下层考虑多模式之间的相互影响,运用变分不等式描述个体出行者的模式路径选择;上层根据不同的管理目标构建数学规划模型.采用遗传模拟退火算法对数值算例进行求解,结果显示了道路收费对系统各种指标的影响和改善.

关键词：道路收费尾气排放模式选择均衡约束数学规划遗传模拟退火算法

考虑共乘激励与费用分摊比例异质性的停车收费模型

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系统工程理论与实践 2023年第4期43卷 1220-1231页

作者：徐红利余静徐薇张开基南京大学工程管理学院南京210093

本文针对单个OD对的简单交通网络,研究考虑共乘激励的交通流分配和停车收费策略.首先,考虑共乘费用分摊比例的异质性,共乘匹配的成功率,公交车内的拥挤效应和道路拥挤效应等,构建了考虑公交车、共乘司机、共乘乘客、独自驾驶等4种出行... 详细信息

本文针对单个OD对的简单交通网络,研究考虑共乘激励的交通流分配和停车收费策略.首先,考虑共乘费用分摊比例的异质性,共乘匹配的成功率,公交车内的拥挤效应和道路拥挤效应等,构建了考虑公交车、共乘司机、共乘乘客、独自驾驶等4种出行方式的交通流分配模型;然后,通过实施停车费优惠以激励共乘出行,建立了考虑共乘费用分摊比例异质性的停车收费模型.对无共乘、有共乘、实施共乘激励等三种情景展开算例分析,结果表明,共乘成本的分摊比例影响出行者参与共乘的固定成本,进而影响共乘司机和乘客匹配的成功率,匹配成功率较低的情况下共乘双方的期望出行成本都会很高,从而导致出行者共乘意愿降低甚至没有意愿参与共乘.此外,共乘的引入对于出行者和系统的效率是双赢的,而合理的停车收费和共乘激励可以显著增加出行者参与共乘的意愿,增加共乘匹配成功的人数,降低大部分出行者的出行成本,并提高系统效率.

关键词：共乘激励用户均衡停车收费出行者异质性

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