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可视化椎间孔镜技术与纤维内窥镜下椎间盘切除术治疗腰椎侧隐窝狭窄症的近期疗效比较

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中国脊柱脊髓杂志 2018年第4期28卷 330-335页

作者：徐峰李涛解放军武汉总医院武汉市430000 湖北中医药大学研究生院武汉市430070

目的 :比较可视化椎间孔镜技术(可视化经皮经椎间孔内窥镜下椎间盘切除术,visualization of percutaneous transforaminal endoscopic discectomy,VPTED)与显微内窥镜下椎间盘切除术(microendoscopic discectomy,MED)治疗腰椎侧隐窝狭窄症的近期临床疗效。方法 :选取我院2016年3月~2017年3月收治的49例单节段腰椎侧隐窝狭窄合并腰椎间盘突出症患者,其中21例接受VPTED治疗,28例接受MED治疗,记录两组患者的手术切口长度、术中透视次数、手术时间、住院天数、住院费用;采用视觉模拟评分法(visual analogue scale/score,VAS)评估手术疗效,应用Oswestry功能指数(Oswestry disability index,ODI)评价临床疗效,末次随访行改良Mac Nab标准评估患者的疗效。结果:两组患者年龄、男女比例、随访时间、腰痛症状、肌力减退、感觉障碍及腱反射、突出节段(L3/4、L4/5、L5/S1)等一般情况无统计学差异(P>0.05)。两组组内术后与术前VAS、ODI评分相比有统计学差异(P0.05)。VPTED组手术切口长度(0.78±0.06cm)较MED组(1.95±0.12cm)小,手术时间(87.51±30.46min)较MED组(47.53±13.61min)长,透视次数(15.86±2.66)较MED组(2.18±0.38)多,差异有统计学意义(P0.05);末次随访改良Mac Nab标准评估疗效,VPTED组优17例,良3例,可1例,优良率为95.24%;MED组优22例,良4例,可2例,优良率为92.86%,两组优良率比较差异无统计学意义(P>0.05)。结论 :可视化椎间孔镜技术与显微内窥镜下椎间盘切除术治疗腰椎侧隐窝狭窄症近期疗效良好,是一种安全、有效的微创手术方式。

关键词：腰椎管狭窄症腰椎间盘突出症椎间孔镜椎间盘镜微创技术

From waste to wealth:Coal tar residue derived carbon materials as low-cost anodes for potassium-ion batteries

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 464-475页

作者： Zhonghua Lu Jun Shen Xin Zhang Lingcong Chao Liang Chen Ding Zhang tao Wei Shoudong xu College of Chemical Engineering and Technology Taiyuan University of TechnologyTaiyuan 030024China College of Chemistry Taiyuan University of TechnologyTaiyuan 030024China School of Chemical Engineering and Pharmacy Wuhan Institute of TechnologyWuhan 430205China School of Energy and Power Jiangsu University of Science and TechnologyZhenjiang 212003China

Carbon materials are widely recognized as highly promising electrode materials for various energy storage system *** tar residues(CTR),as a type of carbon-rich solid waste with high value-added utilization,are crucially important for the development of a more sustainable *** this study,we employed a straightforward direct carbonization method within the temperature range of 700-1000℃to convert the worthless solid waste CTR into economically valuable carbon materials as anodes for potassium-ion batteries(PIBs).The effect of carbonization temperature on the microstructure and the potassium ions storage properties of CTR-derived carbons(CTRCs)were systematically explored by structural and morphological characterization,alongside electrochemical performances *** on the co-regulation between the turbine layers,crystal structure,pore structure,functional groups,and electrical conductivity of CTR-derived carbon carbonized at 900℃(CTRC-900H),the electrode material with high reversible capacity of 265.6m Ah·g^(-1)at 50 m A·g^(-1),a desirable cycling stability with 93.8%capacity retention even after 100 cycles,and the remarkable rate performance for PIBs were ***,cyclic voltammetry(CV)at different scan rates and galvanostatic intermittent titration technique(GITT)have been employed to explore the potassium ions storage mechanism and electrochemical kinetics of *** indicate that the electrode behavior is predominantly governed by surface-induced capacitive processes,particularly under high current densities,with the potassium storage mechanism characterized by an“adsorption-weak intercalation”*** work highlights the potential of CTR-based carbon as a promising electrode material category suitable for high-performance PIBs electrodes,while also provides valuable insights into the new avenues for the high value-added utilization of CTR.

关键词： coal tar residue carbon materials anode potassium-ion batteries high value-added

丹参酮ⅡA亚微乳抗肿瘤作用及对逆转SMMC-7721/VCR肿瘤多药耐药的影响

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中国临床药理学杂志 2017年第5期33卷 427-430页

作者：冯欣张须学冯涛聚迟栋南阳医学高等专科学校河南南阳473000 南阳市中医院河南南阳473000

目的研究丹参酮ⅡA亚微乳的抗肿瘤作用及逆转人肝癌耐药细胞株SMMC-7721/VCR肿瘤的多药耐药性的作用。方法体外培养人肝癌细胞SMMC-7721及SMMC-7721/VCR细胞,每种细胞都分为3组:实验组(细胞悬液+3种化疗药)、阴性对照组(细胞悬液+培养液... 详细信息

目的研究丹参酮ⅡA亚微乳的抗肿瘤作用及逆转人肝癌耐药细胞株SMMC-7721/VCR肿瘤的多药耐药性的作用。方法体外培养人肝癌细胞SMMC-7721及SMMC-7721/VCR细胞,每种细胞都分为3组:实验组(细胞悬液+3种化疗药)、阴性对照组(细胞悬液+培养液)和空白对照组(培养液)。丹参酮ⅡA亚微乳和丹参酮ⅡA以5个浓度(0.5,1.0,2.0,4.0,8.0μg·m L^(-1))对SMMC-7721细胞作用,用四甲基偶氮唑蓝(MTT)法,检测丹参酮ⅡA和丹参酮ⅡA亚微乳作用24,48 h对SMMC-7721细胞的抑制作用;同时,检测长春新碱、顺铂、5-氟尿嘧啶(5-FU)这3种化疗药对SMMC-7721、SMMC-7721/VCR细胞株及丹参酮ⅡA亚微乳干预后的SMMC-7721/VCR细胞株的半数抑制浓度(IC50),观察丹参酮ⅡA亚微乳干预前后耐药细胞株的药敏性变化及药物逆转效果。结果前4个浓度丹参酮ⅡA亚微乳对SMMC-7721细胞作用48 h的抑制率分别为47.93%,55.92%,66.34%,95.61%,IC50为(0.67±0.32)μg·m L^(-1);丹参酮ⅡA对其的抑制率分别为38.83%,49.31%,58.24%,82.46%,IC50为(1.91±0.53)μg·m L^(-1),两者相比差异均有统计学意义(均P<0.01)。丹参酮ⅡA亚微乳对SMMC-7721细胞的抑制率随着浓度的增加而逐渐升高,呈剂量依赖性和时间依赖性。0.5μg·m L^(-1)丹参酮ⅡA亚微乳浓度对SMMC-7721细胞及SMMC-7721/VCR细胞的生长抑制率分别为9.53%,7.74%(均<10%),说明两者均无明显毒性作用。0.5μg·m L^(-1)丹参酮ⅡA亚微乳干预SMMC-7721/VCR细胞,长春新碱对SMMC-7721/VCR的半数抑制浓度由(12.27±0.84)μg·m L^(-1)降为(3.25±0.14)μg·m L^(-1),逆转倍数为3.78。顺铂对SMMC-7721/VCR的半数抑制浓度由(20.42±0.18)μg·m L^(-1)降为(6.98±0.99)μg·m L^(-1),逆转倍数是2.93;5-FU对SMMC-7721/VCR的半数抑制浓度由(35.21±0.68)μg·m L^(-1)降为(18.27±2.18)μg·m L^(-1),逆转倍数分别为1.93。与对SMMC-7721细胞作用相比,长春新碱、顺铂、5-FU对SMMC-7721/VCR细胞作用差异均有统计学意义(P<0.01)。与丹参酮ⅡA亚微乳干预后的SMMC-7721/VCR细胞作用相比,长春新碱、顺铂、5-FU对SMMC-7721/VCR细胞作用差异均有统计学意义(P<0.01)。结论丹参酮ⅡA亚微乳可以抑制SMMC-7721细胞及SMMC-7721/VCR细胞的生长;丹参酮ⅡA亚微乳在体外能够部分逆转SMMC-7721/VCR的多药耐药性。

关键词：丹参酮ⅡA 亚微乳抗肿瘤逆转多药耐药半数抑制浓度

正交试验在聚合物改性水泥砂浆力学性能研究中的应用

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数学的实践与认识 2017年第19期47卷 176-188页

作者：李娜徐洪涛冯虎郑州工商学院公共基础教学部河南郑州451400 郑州大学综合设计研究院有限公司河南郑州450002 郑州大学土木工程学院河南郑州450002

通过正交试验研究聚合物改性水泥砂浆的力学性能.考察了水胶比(A)、聚胶比(B)、砂胶比(C)及集灰比(D)四个因素,每个因素四个水平,采用L_(16)(4~5)正交表进行试验安排.研究发现,各因素对不同力学性能指标影响显著程度的排序不尽相同,且... 详细信息

通过正交试验研究聚合物改性水泥砂浆的力学性能.考察了水胶比(A)、聚胶比(B)、砂胶比(C)及集灰比(D)四个因素,每个因素四个水平,采用L_(16)(4~5)正交表进行试验安排.研究发现,各因素对不同力学性能指标影响显著程度的排序不尽相同,且重复试验方差分析所对应的因素显著程度高于无重复试验;重复试验的方差分析表明:砂胶比(C)及集灰比(D)是影响抗折强度显著因素;聚胶比(B)及集灰比(D)是影响抗压强度的显著因素.

关键词：正交试验因素水平聚合物改性水泥砂浆力学性能

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危桥加固维修过程中关键施工技术的应用

工程建设与设计 2019年第21期 240-242页

作者：封旭涛陕西省西安公路管理局

结合实际,对危桥加固维修过程中应用的关键技术进行研究,阐述危桥概念及危桥加固内容,在总结危桥加固具体流程的同时,对维修过程中关键施工技术应用要点进行介绍。实践可知,在危桥加固维修过程中合理应用塞缝灌浆施工技术、上下部结构... 详细信息

结合实际,对危桥加固维修过程中应用的关键技术进行研究,阐述危桥概念及危桥加固内容,在总结危桥加固具体流程的同时,对维修过程中关键施工技术应用要点进行介绍。实践可知,在危桥加固维修过程中合理应用塞缝灌浆施工技术、上下部结构加固施工技术与增设主梁加固技术等,能提高危桥安全性与质量。

关键词：危桥加固维修关键技术应用

The Convergence of Parameter Estimates and the Real Structure Information of Plant are both Unnecessary for a General Self-Tuning Control System - Arbitrary Deterministic Plant

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The Convergence of Parameter Estimates and the Real Structur...

Müller cells are activated in response to retinal outer nuclear layer degeneration in rats subjected to simulated weightlessness conditions

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作者： Weicun Zhang, Qing Li , Yinmei xu, tao feng School of Automation Science and Electrical Engineering University of Science and Technology Beijing Beijing 100083 P. R. China

This paper is concerned with the stability and convergence of a general deterministic self-tuning control （STC） system, which consists of arbitrary control strategy and arbitrary estimation algorithm. The plant may be linear or non-linear, time-invariant or time varying. The conditions required for global stability and convergence are relaxed, i.e., the convergence of parameter estimates and the real structure information of plant are both removed. It is therefore argued that external excitation signal is not necessary for deterministic STC system. In other words, feedback information of STC system itself is sufficient to achieve the control objective （regulation or tracking）. The key point is that with the help of Virtual Equivalent System （VES） concept, the original nonlinear dominant （nonlinear in structure） problem of STC is converted to a linear dominant （linear in structure） problem- deterministic slow switching control system.

关键词： deterministic self-tuning control stability convergence virtual equivalent system slow switching

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Neural Regeneration Research 2025年第7期20卷 2116-2128页

作者： Yuxue Mu Ning Zhang Dongyu Wei Guoqing Yang Lilingxuan Yao Xinyue xu Yang Li Junhui xue Zuoming Zhang tao Chen Aerospace Clinical Medical Center School of Aerospace MedicineAir Force Medical UniversityXi’anShaanxi ProvinceChina Department of Aviation Medicine Xijing HospitalAir Force Medical UniversityXi’anShaanxi ProvinceChina Department of Emergency Medicine Wuhan No.1 HospitalWuhanHubei ProvinceChina Third Regiment School of Basic MedicineAir Force Medical UniversityXi’anShaanxi ProvinceChina Fourth Regiment School of Basic MedicineAir Force Medical UniversityXi’anShaanxi ProvinceChina

A microgravity environment has been shown to cause ocular damage and affect visual acuity,but the underlying mechanisms remain ***,we established an animal model of weightlessness via tail suspension to examine the pathological changes and molecular mechanisms of retinal damage under *** 4 weeks of tail suspension,there were no notable alterations in retinal function and morphology,while after 8 weeks of tail suspension,significant reductions in retinal function were observed,and the outer nuclear layer was thinner,with abundant apoptotic *** investigate the mechanism underlying the degenerative changes that occurred in the outer nuclear layer of the retina,proteomics was used to analyze differentially expressed proteins in rat retinas after 8 weeks of tail *** results showed that the expression levels of fibroblast growth factor 2(also known as basic fibroblast growth factor)and glial fibrillary acidic protein,which are closely related to Müller cell activation,were significantly *** addition,Müller cell regeneration and Müller cell gliosis were observed after 4 and 8 weeks,respectively,of simulated *** findings indicate that Müller cells play an important regulatory role in retinal outer nuclear layer degeneration during weightlessness.

关键词： glial fibrous acidic protein gliosis Müller cells nerve growth factor neural differentiation neurodegeneration proteomic retinal degeneration retinal outer nuclear layer simulated weightlessness

Effect of lamellarization on the microstructure and mechanical properties of marine 10Ni5CrMoV steel

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 402-413页

作者： tao Zou Yanwu Dong Zhouhua Jiang Shuyang Du Yushuo Li School of Metallurgy Northeastern UniversityShenyang 110819China Key Laboratory of Rolling and Automation Northeastern UniversityShenyang 110819China Key Laboratory for Ecological Metallurgy of Multimetallic Ores(Ministry of Education) Northeastern UniversityShenyang 110819China

Multistage heat treatment involving quenching(Q),lamellarizing(L),and tempering(T)is applied to marine 10Ni5CrMoV *** microstructure and mechanical properties were studied by multiscale characterizations,and the kinetics of reverse austenite transformation,strain hardening behavior,and toughening mechanism were further *** lamellarized specimens possess low yield strength but high toughness,especially cryogenic *** leads to the development of film-like reversed austenite at the martensite block and lath boundaries,refining the martensite structure and lowering the equivalent grain *** analysis of austenite reversion based on the JMAK model shows that the isothermal transformation is dominated by the growth of reversed austenite,and the maximum transformation of reversed austenite is reached at the peak temperature(750℃).The strain hardening behavior based on the modified Crussard-Jaoul analysis indicates that the reversed austenite obtained from lamellarization reduces the proportion of martensite,significantly hindering crack propagation via martensitic transformation during the *** a consequence,the QLT specimens exhibit high machinability and low yield *** with the QT specimen,the ductile-brittle transition temperature of the QLT specimens decreases from-116 to-130℃due to the low equivalent grain size and reversed austenite,which increases the cleavage force required for crack propagation and absorbs the energy of external load,*** work provides an idea to improve the cryogenic toughness of marine 10Ni5CrMoV steel and lays a theoretical foundation for its industrial application and comprehensive performance improvement.

关键词： 10Ni5CrMoV steel lamellarizing reversed austenite cryogenic toughness ductile-brittle transition temperature

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基于预测的计算网格负载平衡研究

航空计算技术 2006年第2期36卷 82-85页

作者：陈世浩宋东徐烽涛西北工业大学航空学院陕西西安710072 奥利金高性能计算技术有限公司浙江湖州313000

计算网格中负载平衡有着重要的作用和显著的效果。预测节点性能是实现动态负载平衡的关键,本文首先引入预测网格节点性能的指数平滑算法,讨论了平滑系数的选取方法。然后设计一个负载平衡实验,实验证明使用基于该预测算法的动态负载平... 详细信息

计算网格中负载平衡有着重要的作用和显著的效果。预测节点性能是实现动态负载平衡的关键,本文首先引入预测网格节点性能的指数平滑算法,讨论了平滑系数的选取方法。然后设计一个负载平衡实验,实验证明使用基于该预测算法的动态负载平衡与静态负载平衡和不使用负载平衡时任务执行效率有明显的提高。

关键词：计算网格预测指数平滑负载平衡