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Ring-Shaped Jets in Gamma-Ray Bursts

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Chinese Journal of Astronomy and Astrophysics 2008年第4期8卷 411-420页

作者： Ming xu Yong-feng huang Si-Wei Kong Department of Astronomy Nanjing University Nanjing 210093 China

When the axis of a gamma-ray burst （GRB） does not coincide with the spin axis of its source, there may result a ring-shaped jet. Using some refined jet dynamics, we calculate multi-wavelength afterglow light curves for such ring-shaped jets. In the R-band we find an obvious break in the afterglow light curve due to the beaming effect and the break is affected by many parameters, such as the electron energy fraction ζe, the magnetic energy fraction ζB^2, the width of ring △θ and the medium number density n. The overall light curve can be divided into three power-law stages, i.e., an ultra-relativistic stage, an after-break stage and a deep Newtonian stage. For each stage the power-law index is larger in the ring-shaped jet than in the corresponding conical jet.

关键词： gamma rays bursts - ISM jets and outflows

Empirical Line Method Using Spectrally Stable Targets to Calibrate IKONOS Imagery

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Pedosphere 2008年第1期18卷 124-130页

作者： xu Jun-feng Institute of Agricultural Remote Sensing and Information Technology Zhejiang University Hangzhou 310029 （China）.

By using speetrally stable targets, the empirical line （EL） method was tested to correct the multispectral IKONOS imagery acquired over Putuo Mountain, Zhejiang, China. A series of calibration targets, which were spectrally stable over time, were selected to establish the linear predicted equation. Subsequently, a series of spectrally stable validation targets were selected to assess the accuracy of the equations. And, validation targets, which were speetrally unstable over time, were used to test the feasibility of using the EL method to calibrate the archival remotely sensed data. Ground reflectance measurements for each target were made using an ASD FieldSpec spectroradiometer. A Trimble GeoXTTM GPS unit with sub-meter accuracy was used to estimate the target position accurately. Linear regression equations for four tKONOS bands were derived. The coefficients of determination for the blue, green, and red bands were all greater than 0.9800 and it was 0.9697 for the near infrared band. It was concluded that reasonable results could be obtained by using speetrally stable targets.

关键词： calibration empirical line method, IKONOS spectrally stable targets

Angular disturbance prediction for countermeasure launcher in active protection system of moving armored vehicle based on an ensemble learning method

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Defence Technology（防务技术） 2023年第3期21卷 207-218页

作者： Chun-ming Li Guang-hui Wang Hai-ping Song xu-feng huang Qi Zhou China North Vehicle Research Institute Beijing100072China School of Aerospace Engineering Huazhong Univerisity of Science and TechnologyWuhan430074China

The active protection system(APS),usually installed on the turret of armored vehicles,can significantly improve the vehicles’survivability on the battlefield by launching countermeasure munitions to actively intercept incoming ***,uncertainty over the launch angle of the countermeasure is increased due to angular disturbances when the off-road armored vehicle is moving over rough ***,accurate and comprehensive angular disturbance prediction is essential to the real-time monitoring of the countermeasure launch *** this paper,a deep ensemble learning(DEL)-based approach is proposed to predict the angular disturbances of the countermeasure launcher in the APS based on previous time-series *** view of the intricate temporal attribute of angular disturbance prediction,the sampling information of historical time series measured by an inertial navigation device is adopted as the input of the developed DEL ***,the recursive multi-step(RMS)prediction strategy and multi-output(MO)prediction strategy are combined with the DEL model to perform the final angular disturbance prediction for the countermeasure launcher in the APS of a moving armored *** proposed DEL model is validated by using the different datasets from real *** results reveal that this approach can be used to accurately predict angular disturbances,with the maximum absolute error of each DOF less than 0.1°.

关键词： prediction disturbance moving

Olanzapine Induces Inflammation and Immune Response via Activating ER Stress in the Rat Prefrontal Cortex

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Current Medical Science 2021年第4期41卷 788-802页

作者： Wen-ting LI xu-feng huang Chao DENG Bao-hua ZHANG Kun QIAN Meng HE Tao-lei SUN School of Chemistry Chemical Engineering and Life SciencesWuhan University of TechnologyWuhan 430070China Illawarra Health and Medical Research Institute and Centre for Translational Neuroscience School of MedicineUniversity of WollongongNSW 2522Australia The National Clinical Research Center for Mental Disorders&Beijing Key Laboratory of Mental Disorders Beijing Anding Hospital&the Advanced Innovation Center for Human Brain ProtectionCapital Medical UniversityBeijing 100069China

Objective Antipsychotics,in particular olanzapine,are first-line medications for *** prefrontal cortex(PFC)is an important region for antipsychotics’therapeutic *** PFC inflammatory and immune pathways are associated with schizophrenia ***,the effect of antipsychotics on the inflammatory and immune pathways in the PFC remains *** aimed to examined the time-dependent effect of olanzapine on inflammatory and immune markers in the PFC of *** the inflammatory and immune pathways are related to endoplasmic reticulum(ER)stress,we further investigated whether or not olanzapine-induced inflammation and immune responses were related to ER *** Expression of pro-inflammatory markers including IkappaB kinaseβ(IKKβ),nuclear factor kappa B(NFκB),tumor necrosis factorα(TNF-α),interleukin-6(IL-6)and IL-1β,and immune-related proteins including inducible nitric oxide synthase(iNOS),toll-like receptor 2(TLR2)and cluster of differentiation 14(CD14)were examined by Western *** Olanzapine treatments for 1,8 and 36 days significantly activated the inflammatory IKKβ/NFκB signaling,and increased the expression of TNF-α,IL-6,IL-1βand immune-related proteins such as iNOS,TLR4 and *** treatment for 1 day,8 and 36 days also induced ER stress in the ***-treatment with an ER stress inhibitor,4-phenylbutyrate,inhibited olanzapine-induced inflammation and the immune response in the *** These results suggested olanzapine exposure could be a factor that induces central inflammation and immunological abnormities in schizophrenia *** induces PFC inflammation and immune response,possibly via activating ER stress signaling.

关键词： olanzapine prefrontal cortex inflammation immune response endoplasmic reticulum stress

Smoking and Serum Lipid Profiles in Schizophrenia

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Neuroscience Bulletin 2016年第4期32卷 383-388页

作者： Hui-Mei An Yun-Long Tan Shu-ping Tan Jing Shi Zhi-Ren Wang Fu-De Yang xu-feng huang Jair C.Soars Thomas R.Kosten Xiang-Yang Zhang Beijing Hui Long Guan Hospital Peking University Centre for Translational Neuroscience School of MedicineIllawarra Health and Medical Research InstituteUniversity of Wollongong Department of Psychiatry and Behavioral Sciences The University of Texas Health Science Center at Houston Department of Psychiatry and Behavioral Sciences Baylor College of Medicine

Schizophrenia is associated with a high preva- lence of cigarette-smoking and abnormal lipid profiles. The purpose of this study was to determine whether the profiles differ between schizophrenic smokers and non-smokers and whether the lipid profiles are related to psychopathological symptoms. Serum lipid profiles were measured in 130 male inpatients with DSM-IV-defined schizophrenia： 104 smokers and 26 non-smokers. Symptoms were assessed using the Positive and Negative Syndrome Scale （PANSS）. Our results showed that positive PANSS symp- toms were fewer in smokers than in non-smokers, while the negative symptoms were fewer in those who smoked more cigarettes. Total protein and globulin levels were significantly lower in the smokers than in the non-smokers. However, there was no significant difference in total cholesterol, triglycerides, high-density lipoprotein choles terol （HDL-c）, low-density lipoprotein cholesterol, apolipoprotein A1, or apolipoprotein B between the smokers and non-smokers. However, the PANSS positive subscale had a significant negative correlation with the HDL-c levels （a protective factor） in the smokers but not in the non-smokers. Our findings suggest that schizophrenic patients who smoke have fewer psychotic symptoms, but contrary to expectation, smoking does not alter lipid profile levels.

关键词： Schizophrenia Nicotine Cigarettesmoking Lipid profiles Symptoms

The effects of antipsychotics on AKT/GSK3 signalling pathway:implications for treatment of memory impairment for schizophrenia

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The effects of antipsychotics on AKT/GSK3 signalling pathway...

No changes in densities of cannabinoid receptors in the superior temporal gyrus in schizophrenia

中国神经科学学会第十届全国学术会议

作者： Mei HAN Chong-Sheng SONG Hong-Qin WANG xu-feng huang Center for Translational Neuroscience School of Health SciencesIHMRIUniversity of Wollongong Center for Biological Psychiatry Beijing HuiLongGuan HospitalPeking University

Objective Cognitive impairment is a core feature of *** impairment of AKT-glycogen synthase kinase 3p(GSK3β) signalling pathway in the hippocampus has been involved in memory impairment in schizophrenia and other schizophrenic *** evidence supports that antipsychotics may partly improve cognition such as memory function in patients with *** study is to investigate the effects of haloperidol and olanzapine in the AKT/GSK3B signalling pathway in the rat hippocampus and understand the possible pharmacological mechanisms of antipsychotics in improving cognitive *** Female rats were treated with haloperidol(0.1mg/kg),olanzapine(1.0mg/kg) or saline for one times,three times/day for 3 days and 6 *** were then sacrificed after two hours once the last injection was *** blotting was employed to determine total and phosphorylated protein levels of AKT and GSK 3β in the hippocampus of female *** analyses were used to detect any differences between treatment and *** Overall,compared to salines,haloperidol and olanzapine showed significant treatment effects on the levels of GSK3β total proteins and phosphorylation of AKT and GSK3β(all P<0.01).Haloperidol treatment significantly increased expression levels in GSK3β total proteins and phosphorylation of GSK3β in the hippocampus after a single ***,olanzapine significantly increased expression levels in phosphorylation of GSK3β.At the three days time-points,haloperidol significantly increased phosphorylation of AKT3β and GSK3β(all P<0.05).Olanzapine significantly increased phosphorylation of GSK3β.Furthermore,both antipsychotics significantly increased phosphorylation of AKT and GSK3β at the six days ***,the total AKT protein levels were significant increased by haloperidol(P<0.05) and had been increased tread by olanzapine(P=0.061) at this *** These results suggested that antipsychotics

关键词： schizophrenia memory impairment glycogen synthase kinase 3β phosphorylation AKT

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Neuroscience Bulletin 2007年第6期23卷 341-347页

作者：邓超韩玫黄旭枫澳大利亚卧龙岗大学健康科学学院

Objective In recent years,abnormal changes in the endocannabinoid system have been found in schizophrenia. The superior temporal gyrus（STG）is strongly implicated in the pathophysiology of schizophrenia,particularly with regards to auditory *** this study,we investigated the binding density of cannabinoid CB1 receptors in the STG of schizophrenia patients compared to control *** Quantitative autoradiography was used to investigate the binding densities of[^3H]SR141716A（a selective antagonist）and[^3H]CP-55940（an agonist）to the CB1 receptors in the ***-mortem brain tissue was obtained from the NSW Tissue Resource Centre（Australia）.Results Contrasting to previous findings in the alterations of CB1 receptor densities in the prefrontal,anterior and posterior cingulate cortex of schizophrenia,which were suggested to be associated to impairment of cognition function,no significant difference was found between the schizophrenia and control cases in both[^3H]SR141716A and[^3H]CP-55940 binding. Conclusion We suggest that CB1 receptors in the STG are not involved in the pathology of schizophrenia and the auditory hallucination symptom of this disease.

关键词： schizophrenia cannabinoid receptor autoradiography superior temporal gyrus

Ru doping triggering reconstruction of cobalt phosphide for coupling glycerol electrooxidation with seawater electrolysis

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Journal of Energy Chemistry 2025年第1期100卷 317-326页

作者： Binglu Deng Jie Shen Jinxing Lu Chuqiang huang Zhuoyuan Chen feng Peng Yunpeng Liu School of Materials Science and Hydrogen Energy Foshan University School of Chemistry and Chemical Engineering Guangzhou University Guangdong Key Laboratory for Hydrogen Energy Technologies

Seawater electrolysis is a promising approach for sustainable energy without relying on precious ***,the large-scale seawater electrolysis is hindered by low catalytic efficiency and severe anode corrosion caused by the harmful *** contrast to the oxygen evolution reaction （OER）and chlorin ion oxidation reaction （ClOR）,glycerol oxidation reaction （GOR） is more thermodynamically and kinetically favorable ***,a Ru doping cobalt phosphide （Ru-CoP2） is proposed as a robust bifunctional electrocatalyst for seawater electrolysis and GOR,for the concurrent productions of hydrogen and value-added *** in situ and ex situ characterization analyses demonstrated that Ru doping featured in the dynamic reconstruction process from Ru-CoP2to Ru-CoOOH,accounting for the superior GOR *** coupling GOR with hydrogen evolution was realized by employing Ru-CoP2as both anode and cathode,requiring only a low voltage of 1.43 V at 100 mA cm-2,which was 250 m V lower than that in alkaline *** work guides the design of bifunctional electrocatalysts for energy-efficient seawater electrolysis coupled with biomass resource upcycling.

关键词： Glycerol electrooxidation Hydrogen evolution Ru doping Cobalt phosphide Bifunctional electrocatalysts

The Comparison of the Effect of Oat and Shiitake Mushroom Powder to Prevent Body Weight Gain in Rats Fed High Fat Diet

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Food and Nutrition Sciences 2012年第7期3卷 1009-1019页

作者： Dian Handayani Barbara J. Meyer Jiezhong Chen Patricia Tang Philip Chi Lip Kwok Hak-Kim Chan xu-feng huang Department of Pharmacology and Pharmacy Li Ka Shing Faculty of Medicine The University of Hong Kong Hong Kong Faculty of Pharmacy The University of Sydney Australia Faculty of Pharmacy The University of Sydney Sydney Australia Metabolic Research Centre School of Health Sciences and Illawarra Health and Medical Research Institute (IHMRI) University of Wollongong Wollongong Australia Metabolic Research Centre School of Health Sciences and Illawarra Health and Medical Research Institute (IHMRI) University of Wollongong Wollongong Australia

Preventing obesity could be done by lowering plasma TAG that inhibits adipogenesis. Oat and mushroom beta-glucans in the diet has been reported to lower plasma lipid;however the data focusing on their effects on TAG and obesity are insufficient. In the present study, lowering plasma triacylglycerol, fat deposition, body weight gain (BWG) in rats fed a high fat diet (HFD) was evaluated. Rats in the control group were given HFD only and rats in the treatment group fed HFD enriched with 0.2%, 0.6% and 1.8% (wt:wt) beta-glucan from oats (LD-O, MD-O, HD-O) or mushroom (LD-M, MD-M, HD-M). After 6 weeks dietary intervention, the rats fed HD-M showed significantly lower plasma TAG, total fat mass, white adipose tissue, inguinal fat and BWG level more than HD-O treated rats (p < 0.05). The underlying mechanism in lowering plasma TAG, fat pad masses and BWG in HD-M was increasing ratio of fat faecal to faecal weight which was significantly higher than HD-O (p < 0.05). This study demonstrated that the preventing obesity via lowering plasma TAG and fat deposition was different depending on beta-glucan origin, either from oats and Shiitake mushroom.

关键词： Beta-Glucan Triacylglycerol Fat Deposition Obesity Dietary Fibre