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Selectivity of N170 in the left hemisphere as an electrophysiological marker for expertise in reading Chinese

Neuroscience Bulletin 2012年第5期28卷 577-584页

作者： Jing Zhao Su Li Si-En Lin Xiao-Hua Cao Sheng He xu-chu weng Key Laboratory of Behavioral Science Institute of Psychology Chinese Academy of Sciences Beijing 100101 China Center for Cognition and Brain Disorders Hangzhou Normal University Hangzhou 310000 China Department of Psychology University of Minnesota MN 55455 USA Graduate University of Chinese Academy of Sciences Beijing 100049 China

Objective The left-lateralized N170, an event-related potential component consistently shown in response to alphabetic words, is a robust electrophysiological marker for reading expertise in an alphabetic language. In contrast, such a marker is lacking for expertise in reading Chinese, because the existing results about the lateralization of N170 for Chinese characters are mixed, reflecting complicated factors such as top-down modulation that contribute to the relative magnitudes of N170 in the left and right hemispheres. The present study aimed to explore a potential electrophysiological marker for reading expertise in Chinese with minimal top-down influence. Methods We recorded N170 responses to Chinese characters and three kinds of control stimuli in a content-irrelevant task, minimizing potential top-down effects. Results Direct comparison of the N170 amplitude in response to Chinese characters between the hemispheres showed a marginally significant left-lateralization effect. However, detailed analyses of N170 in each hemisphere revealed a more robust pattern of left-lateralization - the N170 in the left but not the right hemisphere differentiated Chinese characters from control stimuli. Conclusion These results suggest that the selectivity of N170 （a greater N170 in response to Chinese characters than to control stimuli） within the left hemisphere rather than the hemispheric difference of N170 with regard to Chinese characters is an electrophysiological marker for expertise in reading Chinese.

关键词： N170 Chinese character left-lateralization

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Prevalence of developmental dyslexia in primary school children:a protocol for systematic review and meta-analysis

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World Journal of Pediatrics 2022年第12期18卷 804-809页

作者： Li-Ping Yang chun-Bo Li Xiu-Mei Li Man-Man Zhai Jing Zhao xu-chu weng Key Laboratory of Brain Cognition and Education SciencesMinistry of Education55 Zhongshan Avenue WestTianhe DistrictGuangzhou510631China School of Psychology South China Normal UniversityGuangzhou510631China Shanghai Key Laboratory of Psychotic Disorders Shanghai Mental Health CenterShanghai Jiao Tong University School of MedicineShanghai200030China CAS Center for Excellence in Brain Science and Intelligence Technology(CEBSIT) Chinese Academy of ScienceShanghai200031China Institute of Psychology and Behavioral Science Shanghai Jiao Tong UniversityShanghai200030China Institutes of Psychological Sciences Hangzhou Normal UniversityRoom 30119 Shuyuan Building2318 Yuhangtang RoadCangqianYuhang DistrictHangzhou311121China Zhejiang Key Laboratory for Research in Assessment of Cognitive Impairments Hangzhou311121China Institute for Brain Research and Rehabilitation South China Normal UniversityGuangzhou510631China

Background Developmental dyslexia(DD)is a specific impairment during the acquisition of reading skills and may have a lifelong negative impact on *** estimates of the prevalence of DD serve as the basis for evidence-based health resource allocation and policy ***,the prevalence of DD in primary school children varies largely across ***,it is unclear whether there are differences in prevalence in different genders and writing ***,the present study aims to conduct a systematic review and meta-analysis to assess the global prevalence of DD and to explore related *** We will undertake a comprehensive literature search in 14 databases,including EMBASE,PubMed,Web of Science,China National Knowledge Infrastructure and Cochrane,from their inception to June ***-sectional and longitudinal studies that describe the prevalence of DD will be *** quality of the included observational studies will be assessed using the Strengthening the Reporting of Observational Studies in Epidemiology *** risk of bias will be determined by sensitivity analysis to identify publication *** One meta-analysis will be conducted to estimate the prevalence of DD in primary school *** will be assessed in terms of the properties of subjects(e.g.,gender,grade and writing system)and method of diagnosis in the included primary *** analyses will also be performed for population and secondary *** The results will synthesize the prevalence of DD and provide information for policy-makers and public health specialists.

关键词： Developmental dyslexia Prevalence Primary school children Protocol

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The Claustrum Controls Motor Activity Through Anterior Cingulate Cortex Input and Local Circuit Synchronization in a Preparatory Manner

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Neuroscience Bulletin 2023年第10期39卷 1591-1594页

作者： Zi-Qi Kou chun-Yan Chen Mamatsali Abdurahman xu-chu weng chun Hu Hong-Yan Geng Key Laboratory of Brain Cognition and Education ScienceMinistry of EducationSouth China Normal UniversityGuangzhou 510631China Institute for Brain Research and Rehabilitation and Guangdong Key Laboratory of Mental Health and Cognitive ScienceSouth China Normal UniversityGuangzhou 510631China

Motor control has evolved in the nervous systems of animals and motor output is the final result of neural *** previous studies have focused on the classical brain regions for motor coordination,including the cerebell... 详细信息

关键词： Cortex neural processing

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The development of Chinese character recognition:Evidence from an ERP study

The development of Chinese character recognition:Evidence fr...

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中国神经科学学会第四次会员代表大会暨第八届全国学术会议

作者： Xiao-Hua CAO xu-chu weng~* Institute of psychology Chinese Academy of Sciences Beijing 100101 China

＜正＞Objective Reading words elicits a very early evoked potential termed "N170"located in left posterior regions. It is not clear how the left lateralization of the neural networks involved in characters reading changes with *** ran an experiment to addressed this *** Twenty grade 2 students（mean age = 8）,20 grade 4 students（mean age = 10）,20 grade 6 students（mean age = 12）and 16 young adults（mean age = 23） participated in the current study.75 characters ,75 line drawings and 75 face pictures were presented to *** electroencephalogram（EEG） recording was made using an elastic net containing 128 silver chloride plated electrodes embedded in sponges（Electrical Geodesics,Inc., Eugene,Oregon）.Results The results of the experiment as followed,for all participants,in an overall analysis with a 3 （stimulus types） x4（age group）x 2（hemisphere）ANOVA,a significant stimulus types effect was *** comparisons showed that the characters had a larger N170 amplitude than the line drawings,the face pictures had also a larger N170 amplitude than the line drawings.A interaction was found between stimulus types and age group.A main effect of age was not found in the experiment,nor the hemisphere ***-group comparisons found that,grade 2 had a main effect of stimulus types,also grade 4,grade 6 and adults *** characters had a larger N170 amplitude than the line drawings in all age *** comparisons of the characters found that:left hemisphere had a larger N170 amplitude than the right hemisphere in grade 6 and adults *** grade 2 and grade 4 students had not different N170 amplitude between left and right hemisphere.

关键词： development children character N170

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Modulation of neural connectivity during practice of verb generation

Modulation of neural connectivity during practice of verb ge...

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中国神经科学学会第四次会员代表大会暨第八届全国学术会议

作者： Xiao-Ying YANG,Zhi YANG~*,Zong-Wang DONG,xu-chu weng Institute of Psychology,Chinese Academic of Sciences

＜正＞Objective In a functional magnetic resonance imaging study（fMRI）,we adopted within-condition interregional covariance analysis（WICA） to investigate dynamic modulation of a skill learning task on the inter-regional connectivity in the *** Subject performed five fMRI scan sessions,each included four blocks,two for a noun repetition task and two for verb generation *** the first four sessions,the same list nouns were presented while the sequence of the stimuli presentation were *** the last session,a new list nouns were *** data were processed using multiple regression analysis to identify functional regions of interest（ROIs）.The time courses of within each block in the ROIs were further computed for within-condition interregional correlation using WICA（Liu et al.,1999）. The resultant correlation coefficients were examined against those obtained from the time courses for each ROI during rest *** As expected,practice of verb generation improved behavior *** the native performance （the first session）,the verb generation task activated the left posterior cingulate,the left thalamus,the left frontal cortexc, the right insular,the left fusiform gyrus,the right cerebellar hemisphere,and left *** of these regions decreased significantly along with the practice of the ***,when a new word list was introduced,activity in the left frontal area,the right cerebellum and the right frontal cortex increased compared to the practiced *** results were consistent with the findings of Raichle et al.（1994）.Furthermore,the WICA showed that after practice,inter-regional connections for the verb generation gradually reduced and the activation pattern became more ***,in the novel verb generation,a new association between the left insular and left fusiform gyrus was additionally recruited,while connections between the left frontal and left insular,and the right anterior cingulat

关键词： verb generation learning neural connectivity

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Early visual cortex activation correlates better verbal memory in longterm musically trained subjects

Early visual cortex activation correlates better verbal memo...

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中国神经科学学会第四次会员代表大会暨第八届全国学术会议

作者： Zi-Rui HUANG Zhi YANG~* xu-chu weng Laboratory for Higher Brain Functions Institute of Psychology Chinese Academy of Sciences Beijing 100101 China

＜正＞Previous studies have shown that music training could improve many cognitive functions,such as visuo-spatial cognition and verbal *** present study aims to explore neural correlates of verbal memory improvement by music *** used functional magnetic resonance imaging to compare brain activation between long-term music trained and na（i|¨）ve subjects under three conditions:concrete words encoding,concrete word retrieval and pure tone pitch judgment （baseline condition）.The music trained subjects recognized the words more accuracy and more quickly than the na（i|¨）ve subjects during a post recognition *** importantly,we found activation of the early visual cortex in the music group but not in the na（i|¨）ve group during the word retrieval ***-wise random effect and ROI analysis also revealed significant group difference in bilateral early visual cortex,with larger activation volume in the left hemisphere. These findings suggest that long-term music training can induce functional reorganization of the early visual cortex,which in turn may contribute to improvement of verbal memory capability.

关键词： early visual cortex verbal memory music training fMRI

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Smart Cellulose‑Based Janus Fabrics with Switchable Liquid Transportation for Personal Moisture and Thermal Management

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Nano-Micro Letters 2025年第1期17卷 333-347页

作者： Jianfeng Xi Yanling Lou Liucheng Meng Chao Deng Youlu chu Zhaoyang xu Huining Xiao Weibing Wu Jiangsu Co‑Innovation Center of Efficient Processing and Utilization of Forest Resources International Innovation Center for Forest Chemicals and MaterialsJiangsu Provincial Key Lab of Sustainable Pulp and Paper Technology and Biomass MaterialsNanjing Forestry UniversityNanjing 210037People’s Republic of China College of Materials Science and Engineering Nanjing Forestry UniversityNanjing 210037People’s Republic of China Department of Chemical Engineering University of New BrunswickFrederictonNB E3B 5A3Canada Macromolecular Chemistry and Bavarian Polymer Institute University of BayreuthBayreuth 95440Germany

The Janus fabrics designed for personal moisture/thermal regulation have garnered significant attention for their potential to enhance human ***,the development of smart and dynamic fabrics capable of managing personal moisture/thermal comfort in response to changing external environments remains a ***,a smart cellulose-based Janus fabric was designed to dynamically manage personal moisture/*** cotton fabric was grafted with N-isopropylacrylamide to construct a temperature-stimulated transport ***,hydrophobic ethyl cellulose and hydrophilic cellulose nanofiber were sprayed on the bottom and top sides of the fabric to obtain wettability *** fabric exhibits anti-gravity directional liquid transportation from hydrophobic side to hydrophilic side,and can dynamically and continuously control the transportation time in a wide range of 3–66 s as the temperature increases from 10 to 40℃.This smart fabric can quickly dissipate heat at high temperatures,while at low temperatures,it can slow down the heat dissipation rate and prevent the human from becoming too *** addition,the fabric has UV shielding and photodynamic antibacterial properties through depositing graphitic carbon nitride nanosheets on the hydrophilic *** smart fabric offers an innovative approach to maximizing personal comfort in environments with significant temperature variations.

关键词： Directional water transport Cotton fabric Anti-gravity directional liquid transportation Janus wettability

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Prediction and optimization of flue pressure in sintering process based on SHAP

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 346-359页

作者： Mingyu Wang Jue Tang Mansheng chu Quan Shi Zhen Zhang School of Metallurgy Northeastern UniversityShenyang 110819China Liaoning Low-Carbon Steelmaking Technology Engineering Research Center Northeastern UniversityShenyang 110819China Engineering Research Center of Frontier Technologies for Low-Carbon Steelmaking(Ministry of Education) Shenyang 110819China

Sinter is the core raw material for blast *** pressure,which is an important state parameter,affects sinter *** this paper,flue pressure prediction and optimization were studied based on the shapley additive explanation(SHAP)to predict the flue pressure and take targeted adjustment ***,the sintering process data were collected and processed.A flue pressure prediction model was then constructed after comparing different feature selection methods and model algorithms using SHAP+extremely random-ized trees(ET).The prediction accuracy of the model within the error range of±0.25 kPa was 92.63%.SHAP analysis was employed to improve the interpretability of the prediction *** effects of various sintering operation parameters on flue pressure,the relation-ship between the numerical range of key operation parameters and flue pressure,the effect of operation parameter combinations on flue pressure,and the prediction process of the flue pressure prediction model on a single sample were analyzed.A flue pressure optimization module was also constructed and analyzed when the prediction satisfied the judgment *** operating parameter combination was then *** flue pressure was increased by 5.87%during the verification process,achieving a good optimization effect.

关键词： sintering process flue pressure shapley additive explanation prediction optimization

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汉字阅读加工的功能磁共振研究进展

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国际脑血管病杂志 2006年第3期14卷 216-218页

作者：张娜翁旭初罗本燕浙江大学医学院附属第一医院神经内科杭州310003

对阅读基本机制的了解是研究失读症发病机制和对失读症进行康复治疗的基础。功能磁共振成像是一种能显示活体脑内神经活动状态的成像方法,近年来被用于语言学尤其是汉字阅读加工机制的研究。本文对汉字单字加工的偏侧化以及是否存在汉... 详细信息

对阅读基本机制的了解是研究失读症发病机制和对失读症进行康复治疗的基础。功能磁共振成像是一种能显示活体脑内神经活动状态的成像方法,近年来被用于语言学尤其是汉字阅读加工机制的研究。本文对汉字单字加工的偏侧化以及是否存在汉字认知加工的特异脑区等进行综述。

关键词：汉字功能磁共振成像失读症偏侧化

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Morphology engineering of ZnO micro/nanostructures under mild conditions for optoelectronic application

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 498-503页

作者： Liang chu Haoyu Shen Hudie Wei Hongyu Chen Guoqiang Ma Wensheng Yan Institute of Carbon Neutrality and New Energy&School of Electronics and Information Hangzhou Dianzi UniversityHangzhou 310018China School of Applied Physics and Materials Wuyi UniversityJiangmen 529020China

Zinc oxide(ZnO)serves as a crucial functional semiconductor with a wide direct bandgap of approximately 3.37 *** reaction is commonly used in the synthesis of ZnO micro/nanostructures,given its low cost,simplicity,and easy ***,ZnO morphology engineering has become desirable through the alteration of minor conditions in the reaction process,particularly at room *** this work,ZnO micro/nanostructures were synthesized in a solution by varying the amounts of the ammonia added at low temperatures(including room temperature).The formation of Zn^(2+)complexes by ammonia in the precursor regulated the reaction rate of the morphology engineering of ZnO,which resulted in various structures,such as nanoparticles,nanosheets,microflowers,and single ***,the obtained ZnO was used in the optoelectronic application of ultraviolet detectors.

关键词： morphology engineering low temperature ZnO nanosheets microflowers ultraviolet detector

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