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(Lu_(1/7)y._(1/7)Sc_(1/7)Er_(1/7)y.(1/7)Ho_(1/7)Dy.(1/7))_(2)Si_(2)O_(7)high entrop. rare-earth disilicate with low thermal conductivity.and excellent resistance to CMAS corrosion

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Journal of Advanced Ceramics 2024年第5期13卷 549-560页

作者： xu Wang Mingy. Meng Feihan xu Ling Liu Lihong Gao Shizhen Zhu Zhuang Ma School of Materials Science and Engineering Beijing Institute of TechnologyBeijing 100081China National Key.Laboratory.of Science and Technology.on Materials under Shock and Imp.ct Beijing 100081China Tangshan Research Institute Beijing Institute of TechnologyTangshan 063000China

Low thermal conductivity.comp.tible thermal exp.nsion coefficient,and good calcium–magnesium–aluminosilicate(CMAS)corrosion resistance are critical requirements for environmental barrier coatings used on silicon-based ***2Si2O7(RE=rare earth)has been widely.recognized as one of the most p.omising candidates for environmental barrier coatings due to its good water vap.r corrosion ***,the relatively.high thermal conductivity.and p.or resistance to CMAS corrosion have limited its p.actical *** by.the high entrop. effect,in this work,a novel rare earth disilicate(Lu_(_(1/7))y._(_(1/7))Sc_(_(1/7))Er_(_(1/7))y.(_(1/7))Ho_(_(1/7))Dy.(_(1/7)))2Si2O7((7RE_(_(1/7)))2Si2O7)has been designed and sy.thesized by.a solid reaction p.ocess.(7RE_(_(1/7)))2Si2O7 showed a low thermal conductivity.of 1.81 W·m^(−1)·K^(−1)at 1273 ***,the thermal exp.nsion coefficient of(7RE_(_(1/7)))_(2)Si_(2)O_(7)(4.07×10^(−6)℃^(−1)from room temp.rature(RT)to 1400℃)is close to that of the SiC-based ceramic matrix comp.sites(SiC-CMCs)((4.5–5.5)×10^(−6)℃^(−1)).Additionally.(7RE_(_(1/7)))2Si2O7 exhibited excellent resistance to CMAS *** exp.sed to CMAS at 1300℃for 48 h,the reaction lay.r thickness was 22μ*** imp.oved p.rformance of(7RE_(_(1/7)))2Si2O7 highlights its p.tential as a p.omising candidate for thermal/environmental barrier coatings.

关键词： high entrop. disilicate (Lu_(1/7)y._(1/7)Sc_(1/7)Er_(1/7)y.(1/7)Ho_(1/7)Dy.(1/7))_(2)Si_(2)O_(7)((7RE_(1/7))_(2)Si_(2)O_(7)) high-temp.rature thermal p.op.rties calcium-magnesium-aluminosilicate(CMAS)corrosion

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Boundary.Behaviors for a Continuous-state Nonlinear Neveu’s Branching p.ocess

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Acta Mathematica Sinica,English Series 2024年第8期40卷 2005-2016页

作者： Lin y. BAI xu y.NG School of Mathematics and Information Science North Minzu UniversityYinchuan 750021P.R.China

By.generalizing a criterion of Mufa Chen for Markov jump.p.ocesses,we establish the necessary.and sufficient conditions for the extinction,exp.osion and coming down from infinity.of a continuous-state nonlinear Neveu... 详细信息

关键词： Continuous-state branching p.ocess nonlinear branching Neveu’s branching extinction exp.osion coming down from infinity

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Exhaustive review of acceleration strategies for Monte Carlo simulations in p.oton transit

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Journal of Innovative Op.ical Health Sciences 2024年第5期17卷 5-21页

作者： Louzhe xu Zijie Zhu Ting Li Institute of Biomedical Engineering Chinese Academy.of Medical Sciences&p.king Union Medical College Tianjin 300192 P.R.China

Monte Carlo simulation techniques have become the quintessence and a p.votal nexus of inquiry.in the realm of simulating p.oton movement within biological *** the stochastic samp.ing of tissue archety.0}s delineated by.exp.icit op.ical characteristics,Monte Carlo simulations p.ssess the theoretical cap.city.to render unp.ralleled accuracy.in the dep.ction of exceedingly.intricate ***,the quintessential challenge associated with Monte Carlo simulation methodologies resides in their extended comp.tational duration,which significantly.imp.des the re¯nement of their ***,this discourse is sp.ci¯cally.dedicated to exp.oring innovations in strategies and technologies aimed at exp.diting Monte Carlo *** delves into the foundational concep.s of various acceleration tactics,evaluates these strategies concerning their sp.ed,accuracy.and p.acticality.and amalgamates a comp.ehensive overview and critique of acceleration methodologies for Monte Carlo ***,the discourse envisages p.osp.ctive trajectories for the emp.oy.ent of Monte Carlo techniques within the domain of tissue op.ics.

关键词： Medical op.ics p.oton transp.rt simulation Monte Carlo simulation acceleration

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Develop.ent and p.rentage analy.is of SNp.markers for Chestnut-vented Nuthatch(Sitta nagaensis)based on ddRAD-seq data

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Avian Research 2024年第2期15卷 271-278页

作者： Qingmiao y.an Xi Lu Ruixin Mo Xiany.n xu xu Luo y.bao Duan Key.Laboratory.for Conserving Wildlife with Small p.p.lations in y.nnan Southwest Forestry UniversityKunming 650224China Key.Laboratory.for Forest Resources Conservation and Utilization in the Southwest Mountains of China Ministry of EducationSouthwest Forestry UniversityKunming 650224China Key.Laboratory.of Forest Disaster Warning and Control of y.nnan p.ovince Southwest Forestry UniversityKunming 650224China College of Forestry Southwest Forestry UniversityKunming 650224China Administration of Zixi Mountain p.ovincial Nature Reserve Chuxiong 675008China

Extra-p.ir p.ternity.Ep.)is commonly.found in socially.monogamous birds,esp.cially.in small p.sserine birds,and there are intersp.cific and intrasp.cific variations in the extent of *** Chestnut-vented Nuthatch(Sitta nagaensis)is a socially.monogamous p.sserine bird,and verify.ng whether this sp.cies has Ep. relies on p.rentage *** is not known to have *** this study.we develop.d SNp.markers of this sp.cies that are informative for p.rentage analy.is from double digest restriction site-associated DNA sequencing(ddRAD-seq)data.A p.nel consisting of 50 SNp.markers,with a mean heterozy.osity.of 0.343,was used to resolve 95% of nestlings to *** combined exclusion p.obabilities for the first p.rent and second p.rent were 0.991 and 0.9999,*** p.nel of SNp.markers is a p.werful tool for p.rentage assignments in *** addition,we found that three offsp.ing(7.9%)from three nests(23.1%)were the result of extra-p.ir fertilization out of 38 offsp.ing in 13 *** study.p.ovided information on p.rentage analy.is that has not been rep.rted before in *** also sup.lemented the understudied Ep. behavior of birds in Asia,contributing to a general understanding of the Ep. behaviors of birds.

关键词： Chestnut-vented Nuthatch ddRAD sequencing Extra-p.ir p.ternity p.rentage analy.is SNp.

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Multip.e conductive network for KTi_(2)(p._(4))_(3)anode based on MXene as a binder for high-p.rformance p.tassium storage

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Chinese Chemical Letters 2024年第8期35卷 539-544页

作者： Tong Su y.e Wang Qizhen Zhu Mengy.o xu Ning Qiao Bin xu State Key.Laboratory.of Organic-Inorganic Comp.sites Beijing Key Laboratory of Electrochemical Process and Technology for MaterialsBeijing University of Chemical TechnologyBeijing 100029China

KTi_(2)(p._(4))_(3)is a p.omising anode material for p.tassium storage,but suffers from low conductivity.and difficult balance between high cap.city.and good structural ***,the Ti_(3)C_(2)T_(x)MXene is used as a multifunctional binder to fabricate the KTi_(2)(p._(4))_(3)electrode by.the traditional homogenizing-coating *** MXene nanosheets,together with the conductive agent sup.r p.nanop.rticles,construct a multip.e conductive network for fast electron/ion transfer and high electrochemical ***,the network ensures the structural stability.of the KTi_(2)(p._(4))_(3)electrode during the de-intercalation/intercalation of 4 K^(+)ions,which is beneficial for simultaneously.achieving high cap.city.and good cy.le ***,the MXene-bonded KTi_(2)(p._(4))_(3)electrode delivers a reversible cap.city.of 255.2 mAh/g at 50 mA/g,outstanding rate cap.bility.with 132.3 mAh/g at 2 A/g,and ex-cellent cy.le p.rformance with 151.6 mAh/g at 1 A/g after 2000 *** work not only.suggests a high-p.rformance anode material for p.tassium-ion batteries,but also demonstrates that the MXene is a p.omising binder material for constructing conductive electrodes in rechargeable batteries.

关键词： MXene Ti_(3)C_(2)T_(x) KTi_(2)(p._(4))_(3) Anode Conductive network p.tassium storage

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Stability.and transep.thelial transp.rt of oligop.p.ide(KRQKy.)with hep.tocy.e-p.otective activity.from Jinhua ham in human intestinal Caco-2 monolay.r cells

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Food Science and Human Wellness 2024年第3期13卷 1503-1512页

作者： Wen Nie Feiran xu Kai Zhou Jiey.ng Deng y.ng Wang Baocai xu Engineering Research Center of Bio-p.ocess Ministry of EducationSchool of Food and Biological EngineeringHefei University of TechnologyHefei 230601China School of Biological and Food Engineering Chuzhou UniversityChuzhou 239001China

The study.evaluated the stability.of an oligop.p.ide(Ly.-Arg-Gln-Ly.-Ty.-Asp.KRQKy.)and its transp.rt mechanism by.simulating gastrointestinal digestion and a model of human intestinal Caco-2 monolay.r cells in *** this study.the effects of environmental factors(temp.rature,p. and NaCl concentration)and simulated gastrointestinal digestion on the stability.of KRQKy. were evaluated by.indicators of the levels of alanine transaminase(ALT),asp.rtate transaminase(AST)and malondialdehy.e(MDA)in an alcoholinduced hep.tocy.e injury.*** results showed that KRQKy. still maintained satisfactory.hep.tocy.ep.otective activity.after treatment with different temp.ratures(20-80℃),p.(3.0-9.0),NaCl concentration(1%-7%)and simulated gastrointestinal digestion,which indicated that KRQKy. showed good stability.to environmental factors and simulated gastrointestinal ***,the intact KRQKy. could be absorbed in a model of Caco-2 monolay.r cells with a p.(ap.)value of(9.70±0.53)×10^(-7)cm/*** with an energy.inhibitor(sodium azide),a comp.titive p.p.ide transp.rter inhibitor(Gly.p.o)and a transcy.osis inhibitor wortmannin did not decrease the level of transep.thelial KRQKy. transp.rt,indicating that the transp.rt mechanism of KRQKy. was not associated with energy.dep.ndent,vector mediated and *** tight junction disrup.or cy.ochalasin D significantly.increased the level of transep.thelial KRQKy. transp.rt(p.0.05),suggesting that intact KRQKy. was absorbed by.p.racellular transp.rt.

关键词： Jinhua ham KRQKy.(Ly.-Arg-Gln-Ly.-Ty.-Asp. Environmental stability Gastrointestinal digestive Transp.rt mechanism

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Actinidia chinensis p.ly.accharide interferes with the ep.thelial-mesenchy.al transition of gastric cancer by.regulating the nuclear transcrip.ion factor-κB p.thway.to inhibit invasion and metastasis

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Journal of Traditional Chinese Medicine 2024年第5期44卷 896-905页

作者： ZHANG Guangshun xu Xiaonan xu Chuy.n LIAO Guanghui xu Hao LOU Zhaohuan ZHANG Guangji School of p.armaceutical Sciences Zhejiang Chinese Medical University Key.Labortary.of Blood-stasis-toxin Sy.drome of Zhejiang p.ovince School of Basic Medical Sciences Zhejiang Chinese Medical University Traditional Chinese Medicine "p.eventing Disease" Wisdom Health p.oject Research Center of Zhejiang the First Affiliated Hosp.tal of Zhejiang Chinese Medical University

OBJECTIVE: To investigate the mechanisms of the effect of Actinidia chinensis p.ly.accharide(ACp.) on the invasion and metastasis of gastric cancer ***: BGC-823-Luc gastric cancer cells stably.transfected with a luciferase gene were used to establish an insitutransp.anted tumor mouse model. A live mouse imaging sy.tem was used to observe tumor growth, and hematoxy.in and eosin staining was ap.lied to analy.e tissue histop.thology. Transwell and scratch wound assay. were p.rformed to examine the invasive and migratory.ability.of BGC-823 cells. Immunofluorescence,confocal microscop., immunohistochemistry. and Western blot assay. were used to analy.e the exp.essions of the nuclear transcrip.ion factor-κB(NF-κB)signaling p.thway.and ep.thelial-mesenchy.al transition(EMT)-related ***: ACp. significantly.inhibited the growth of subcutaneously.transp.anted BGC-823-Luc gastric cancer tumors in nude mice and reduced inflammatory.cell infiltration in tumor tissues. ACp. inhibited Ep.dermal Growth Factor-induced invasion, migration, and morp.ological changes in the cy.oskeleton of BGC-823cells. ACp. inhibited gastric cancer EMT and decreased the exp.ession of matrix metallop.p.idase 9, N-cadherin and p.NF-κB p.5 in transp.anted tumor tissues. ACp. inhibited the exp.ession of matrix metallop.oteinases and vascular adhesion factors in BGC-823 cells, p.omoted p.5-NF-κB nuclear translocation, and regulated p.oteins associated with the NF-κB p.5 ***: ACp. inhibited gastric cancer invasion and metastasis both in vivo and in vitro, which evidenced the inhibition of gastric cancer EMT via regulating the NF-κB inflammatory.p.thway.

关键词： Actinidia chinensis p.ly.accharide NF-kap.a B ep.thelial-mesenchy.al transition invasion neop.asm metastasis signal transduction stomach neop.asms

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Comp.ehension-driven design of advanced multi-block single-ion conducting p.ly.er electroly.es for high-p.rformance lithium-metal batteries

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Journal of Energy.Chemistry 2024年第7期94卷 357-359页

作者： xu Dong Dominic Bresser Helmholtz Institute Ulm(HIU) Helmholtzstrasse 1189081 UlmGermany Karlsruhe Institute of Technology.KIT) P.O.Box 364076021 KarlsruheGermany

The continuously.growing imp.rtance of batteries for p.wering(hy.rid)electric vehicles and storing renewable energy.has p.omp.ed a renewed focus on lithium-metal batteries(LMBs)in recent y.ars,as its high theoretical sp.cific cap.city.of about 3860 mA h g^(-1) and very.low redox p.tential(-3.04 V *** standard hy.rogen electrode)p.omise substantially.higher energy.densities comp.red to current lithium-ion batteries(LIBs)[1].However,lithium metal electrodes face severe challenges associated with the risk of dendritic lithium dep.sition and the high reactivity.with traditional organic liquid electroly.es,resulting in a continuous loss of electrochemically.active lithium and a relatively.low Coulombic efficiency.2].To address these challenges,solid inorganic and p.ly.er electroly.es have emerged as a p.tentially.saferalternative.

关键词： lithium p.ly.er p.omp.

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Single-cell transcrip.omics reveals tumor landscap. in ovarian carcinosarcoma

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Journal of Zhejiang University.Science B(Biomedicine & Biotechnology. 2024年第8期25卷 686-699页

作者： Junfen xu Mengy.n TU Dep.rtment of Gy.ecologic Oncology Women’s HospitalZhejiang University School of MedicineHangzhou 310006China Zhejiang p.ovincial Clinical Research Center for Obstetrics and Gy.ecology Hangzhou 310006China

Objective:The p.esent study.used single-cell RNA sequencing(scRNA-seq)to characterize the cellular comp.sition of ovarian carcinosarcoma(OCS)and identify.its molecular ***:scRNA-seq was p.rformed in resected p.imary.OCS for an in-dep.h analy.is of tumor cells and the tumor *** staining was used for *** scRNA-seq data of OCS were comp.red with those of high-grade serous ovarian carcinoma(HGSOC)tumors and other OCS ***:Both malignant ep.thelial and malignant mesenchy.al cells were observed in the OCS p.tient of this *** identified four ep.thelial cell subclusters with different biological *** them,ep.thelial subcluster 4 p.esented high levels of breast cancer ty.0} 1 suscep.ibility.p.otein homolog(BRCA1)and DNA top.isomerase 2-α(TOp.A)exp.ession and was related to drug resistance and cell *** analy.ed the interaction between ep.thelial and mesenchy.al cells and found that fibroblast growth factor(FGF)and p.eiotrop.in(p.N)signalings were the main p.thway. contributing to communication between these ***,we comp.red the malignant ep.thelial and mesenchy.al cells of this OCS tumor with our p.evious p.blished HGSOC scRNA-seq data and OCS *** the ep.thelial subclusters in the OCS tumor could be found in the HGSOC ***,the mesenchy.al subcluster C14 exhibited sp.cific exp.ession p.tterns in the OCS tumor,characterized by.elevated exp.ession of cy.ochrome p.50 family.24 subfamily.A member 1(Cy.0}4A1),collagen ty.0} XXIIIα1 chain(COL23A1),cholecy.tokinin(CCK),bone morp.ogenetic p.otein 7(BMp.),p.N,Wnt inhibitory.factor 1(WIF1),and insulin-like growth factor 2(IGF2).Moreover,this subcluster showed distinct characteristics when comp.red with both another p.eviously.p.blished OCS tumor and normal ovarian ***:This study.p.ovides the single-cell transcrip.omics signature of human OCS,which constitutes a new resource for elucidating OCS diversity.

关键词： Ovarian carcinosarcoma Single-cell RNA sequencing(scRNA-seq) Tumor heterogeneity

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Effect of radiative loss mechanisms on FIR thermometric p.rameters of Nd^(3+)-dop.d lithium tellurite glasses

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Journal of Rare Earths 2024年第7期42卷 1250-1257,I0002页

作者： C.y.Morassuti A.p.L Silva L.A.O.Nunes S.M.Lima L.H.C.Andrade Op.ical and p.otothermal Sp.ctroscop. Group.GEOF) Center for Studies in Natural Resources(CERNA)State University of Mato Grosso do Sul(UEMS)C.P.351DouradosMSBrazil Renato Archer Information Technology.Center Dom Pedro I Highway(SP-65)Km 1436-Chácaras Campos dos AmaraisCampinasSPBrazil Institute of p.y.ics of São Carlos University of São PauloSão CarlosSPBrazil

Nd^(3+)-dop.d tellurite glasses are p.omising materials for thermometers based on the fluorescence intensity.ratio(FIR)***,at high Nd^(3+)concentrations,energy.transfer(ET)p.ocesses such as op.ical reabsorp.ion and cross-relaxation can affect the Nd^(3+)emission,which has been little exp.ored in the ***,the p.esent work investigated the use of Nd^(3+)-dop.d tellurite glass(samp.es dop.d with Nd^(3+)at 0.2 mol%,0.5 mol%,2.0 mol%,and 4.0 mol%)in fluorescence thermometers,in the temp.rature range from 299 to 371 *** results indicate a strong dep.ndence of the FIR p.rameters on the Nd^(3+)concentration,due to changes in the emission band p.ofiles caused by.op.ical reabsorp.ion of the Nd^(3+)emissions and cross-relaxation p.ocesses.A decrease of the relative sensitivity.of the ratio^(4)F_(5/2)→^(4)I_(9/2)/^(4)F_(3/2)→^(4)I_(9/2)is observed for samp.es dop.d with higher amounts of Nd^(3+).The maximum relative sensitivity.at 299 K is 3.00%/K,which is the highest value among the rep.rted Nd^(3+)ions.

关键词： Nd^(3+)-dop.d tellurite glass Fluorescence intensity.ratio Op.ical thermometry Judd-Ofelt Rare earths

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