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The nucleon pair approximation(NPA) of the shell model

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Science China(Physics,Mechanics & Astronomy) 2011年第2期54卷 215-221页

作者： ZHAO YuMin LEI Yang xu zhengyu JIANG Hui Department of Physics Shanghai Jiao Tong University Shanghai 200240 China Center of Theoretical Nuclear Physics National Laboratory of Heavy Ion Accelerator Lanzhou 730000 China CCAST World Laboratory Beijing 100080 China School of Arts and Science Shanghai Maritime University Shanghai 200135 China

In this paper we discuss the nucleon pair approximation of the shell model,based on our recent results which include a brief introduction to its framework and *** exemplify this model by studies of low-lying states fo... 详细信息

关键词： pair truncation low-lying states heavy nuclei

A Novel Personalized Web Search Model

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Wuhan University Journal of Natural Sciences 2007年第5期12卷 897-901页

作者： ZHU zhengyu xu Jingqiu TIAN Yunyan REN Xiang College of Computer Science Chongqing University Chongqing 400044 China

A novel personalized Web search model is proposed. The new system, as a middleware between a user and a Web search engine, is set up on the client machine. It can learn a user＇s preference implicitly and then generate the user profile automatically. When the user inputs query keywords, the system can automatically generate a few personalized expansion words by computing the term-term associations according to the current user profile, and then these words together with the query keywords are submitted to a popular search engine such as Yahoo or Google. These expansion words help to express accurately the user＇s search intention. The new Web search model can make a common search engine personalized, that is, the search engine can return different search results to different users who input the same keywords. The experimental results show the feasibility and applicability of the presented work.

关键词： search engine personalization term-term association retrieval effectiveness

ROS-responsive nanoparticle delivery of ferroptosis inhibitor prodrug to facilitate mesenchymal stem cell-mediated spinal cord injury repair

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Bioactive Materials 2024年第8期38卷 438-454页

作者： Renshuai Hua Chenxi Zhao zhengyu xu Derong Liu Wenyuan Shen Wenlu Yuan Yan Li Jun Ma Zhishuo Wang Shiqing Feng Department of Orthopedics International Science and Technology Cooperation Base of Spinal Cord InjuryTianjin Key Laboratory of Spine and Spinal Cord InjuryTianjin Medical University General Hospital154 Anshan RoadHeping DistrictTianjin300052China Department of Orthopaedics Qilu Hospital of Shandong UniversityShandong University Centre for OrthopaedicsAdvanced Medical Research InstituteCheeloo College of MedicineShandong UniversityJinanShandong250012China Department of Orthopedics The Second Hospital of Shandong UniversityCheeloo College of MedicineShandong University247 Beiyuan StreetJinanShandong250033China

Spinal cord injury(SCI)is a traumatic condition that results in impaired motor and sensory *** is one of the main causes of neural cell death and loss of neurological function in the spinal cord,and ferroptosis inhibitors are effective in reducing inflammation and repairing *** human umbilical cord mesenchymal stem cells(Huc-MSCs)can ameliorate inflammatory microenvironments and promote neural regeneration in SCI,their efficacy is greatly limited by the local microenvironment after ***,in this study,we constructed a drug-release nanoparticle system with synergistic Huc-MSCs and ferroptosis inhibitor,in which we anchored Huc-MSCs by a Tz-A6 peptide based on the CD44-targeting sequence,and combined with the reactive oxygen species(ROS)-responsive drug nanocarrier mPEG-b-Lys-BECI-TCO at the other end for SCI ***,we also modified the classic ferroptosis inhibitor Ferrostatin-1(Fer-1)and synthesized a new prodrug Feborastatin-1(Feb-1).The results showed that this treatment regimen significantly inhibited the ferroptosis and inflammatory response after SCI,and promoted the recovery of neurological function in rats with *** study developed a combination therapy for the treatment of SCI and also provides a new strategy for the construction of a drug-coordinated cell therapy system.

关键词： Spinal cord injury Huc-MSCs ROS-Responsive nanoparticles Ferroptosis inhibitor

Strong dual-crosslinked hydrogels for ultrasound-triggered drug delivery

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Nano Research 2019年第1期12卷 115-119页

作者： Wenxu Sun Heting Jiang Xin Wu zhengyu xu Chen Yao Juan Wang Meng Qin Qing Jiang Wei Wang Dongquan Shi Yi Cao Collaborative Innovation Center of Advanced Microstructures National Laboratory of Solid State Microstructureand Department of PhysicsNanjing UniversityNanjing 210093China Department of Sports Medicine and Adult Reconstructive surgery Drum Tower HospitalMedical SchoolState Key Laboratory of Analytical Chemistry for Life ScienceNanjing UniversityNanjing 210008China Joint Research Center far Bone and Joint Disease Model Animal Research Center(MARC)School of Chemistry and Chemical Engineeringand State Key Laboratory of Analytical Chemistry far Life ScienceNanjing UniversityNanjing 210093China

Hydrogels that can respond to dynamic forces either from endogenous biological activities or from external mechanical stimuli show great promise as novel drug delivery systems (DDS).However,it remains challenging to engineer hydrogels that specifically respond to externally applied mechanical forces with minimal basel drug leakage under normal stressful physiological *** we present an ultrasound responsive hydrogel-based DDS with special dual-crosslinked nanoscale network *** covalent crosslinks endow the hydrogel high mechanical stability and greatly suppress deformation-triggered drug ***,the dynamic covalent boronate ester linkages between hydrogel backbone and the anti-inflammation compound,tannic acid (TA),allow effective ultrasound-triggered pulsetile release of *** such,the hydrogel shows distinct drug release profiles under compression and ultrasound.A proof-of-principle demonstration of the suppression of inflammation activation of macrophage upon ultrasound-triggered release of TA was also *** anticipate that this novel hydrogel-based drug delivery system can be used for the treatment of inflammatory diseases on load-bearing tissues,such as muscle and cartilage.

关键词： hydrogel dynamic covalent bond mechanical force drug release

Stretchable and self-healable hydrogel artificial skin

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National Science Review 2022年第7期9卷 43-55页

作者： Bin xue Hui Sheng Yongqiang Li Lan Li Weishuai Di zhengyu xu Linjie Ma Xin Wang Haoting Jiang Meng Qin Zhibo Yan Qing Jiang Jun-Ming Liu Wei Wang Yi Cao National Laboratory of Solid State Microstructures Department of Physics Nanjing University State Key Laboratory of Pharmaceutical Biotechnology Department of Sports Medicine and Adult Reconstructive Surgery Drum Tower Hospital Affiliated to Medical School of Nanjing University Institute for Brain Sciences Nanjing University Chemistry and Biomedicine Innovation Center Nanjing University

Hydrogels have emerged as promising materials for the construction of skin-like mechanical *** common design of hydrogel-based artificial skin requires a dielectric sandwiched between two hydrogel layers for capacitive ***,such a planar configuration limits the sensitivity,stretchability and self-healing ***,we report the design of single-layer composite hydrogels with bulk capacitive junctions as mechanical *** engineer dielectric peptide-coated graphene(PCG) to serve as homogenously dispersed electric double layers in *** mechanical motions that alter the microscopic distributions of PCG in the hydrogels can significantly change the overall *** use peptide self-assembly to render strong yet dynamic interfacial interactions between the hydrogel network and *** resulting hydrogels can be stretched up to 77 times their original length and self-heal in a few *** devices can effectively sense strain and pressure in both air and aqueous environments,providing tremendous opportunities for next-generation iontronics.

关键词： hydrogel capacitive sensor stretchability self-healing self-assembly

Fabrication of W/Cu and Mo/Cu FGM as Plasma-facing Materials

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International Journal of Minerals,Metallurgy and Materials 2000年第2期14卷 122-125页

作者： Changchun Ge Zhangjian Zhou Jiangtao Li Xiang Liu zhengyu xu(Laboratory of Special Ceramics and Powder Metallurgy, University of Science and Technology Beijing, Beijing 100083, China)(Southwest Institute of Nuclear Physics, Chengdu 610041, China) Laboratory of Special Ceramics and Powder Metallurgy University of Science and Technology Beijing Beijing 100083 China Southwest Institute of Nuclear Physics Chengdu 610041 China

W/Cu Functionally Graded Materials (FGM) was designed not only for reducing the thermal stress caused by the mismatch of thermal expansion coefficients, but also for combining the features of W, Mo - high plasma-erosion resistance and the advantages of Cu - high heat conductivity and ductility. Four different fabrication processes for W/Cu or Mo/Cu, including hot-pressing, Cu infiltration of sintered porosity-graded W skeleton, spark plasma sintering and plasma spraying, were investigated and compared. It was foundthat the hot-pressing process is difficult to keep the designed composition gradient, while the other three processes are successful in making W/Cu or Mo/Cu FGM. Meanwhile, microstructures and composition gradients are analyzed with SEM and EDAX.

关键词： FGM plasma-facing material W/Cu and Mo/Cu alloy

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基于地基土等效线性的三维厂址反应分析

核动力工程 2022年第2期43卷 112-116页

作者：屈云光徐征宇中广核工程有限公司核电安全监控技术与装备国家重点实验室广东深圳518124

随着核电厂选址条件的日趋复杂化,土-结构相互作用(SSI)成为核电厂抗震分析需要考虑的重要因素之一。目前经典的自由场厂址反应分析采用的是一维层状地基土的分析,比如SHAKE91、EERA和SASSI等,很难考虑土层的非均质层状因素。因此随着... 详细信息

随着核电厂选址条件的日趋复杂化,土-结构相互作用(SSI)成为核电厂抗震分析需要考虑的重要因素之一。目前经典的自由场厂址反应分析采用的是一维层状地基土的分析,比如SHAKE91、EERA和SASSI等,很难考虑土层的非均质层状因素。因此随着核电安全的监管要求越来越高,抗震的精细化分析成为趋势。本文采用有限元程序ABAQUS编写的UMAT材料子程序,实现了基于地基土材料的等效线性,开展均质层状土的三维自由场厂址反应分析。其计算分析结果与SHAKE91计算结果进行对比表明,在均质层状土条件下吻合较好。因此,本研究为求解复杂非均质地基条件的SSI分析提供了良好的工程适用性。

关键词：土-结构相互作用(SSI) 厂址反应分析均质层状土

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超声速磁流体管道流动的数值模拟

北京航空航天大学学报 2005年第8期31卷 893-898页

作者：许振宇李椿萱北京航空航天大学航空科学与工程学院北京100083

应用可同时适用于描述磁流体MHD (MagnetoHydroDynamic)强化超燃冲压发动机磁流体发电器与磁流体加速器的,包含磁流体N S(Navier Stokes)方程与磁感应方程的可压缩磁流体方程组对超声速磁流体管道流动进行了数值模拟研究,以验证本项工... 详细信息

应用可同时适用于描述磁流体MHD (MagnetoHydroDynamic)强化超燃冲压发动机磁流体发电器与磁流体加速器的,包含磁流体N S(Navier Stokes)方程与磁感应方程的可压缩磁流体方程组对超声速磁流体管道流动进行了数值模拟研究,以验证本项工作所提出的对2组方程进行交替迭代的分裂式算法.给出了算例的计算结果,并与无磁场及恒磁场下相同管道的流动计算结果进行了对比分析.

关键词：磁流体高超声速 TVD(Total Variation Denlinition) 数值模拟

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循环流化床过程仿真的数学模型

计算机与应用化学 2008年第2期25卷 227-232页

作者：许正宇牛凯中国化工信息中心华康达公司北京100029

传统的循环流化床仿真的数学模型都采用反应动力学的方法。本文采用了CSTR的平衡反应算法,对循环流化床建立仿真的数学模型,已用于100MW循环流化床的实际工业装置仿真培训器中,算法比较稳定,模拟了循环流化床的开停车、事故处理和正常操... 详细信息

传统的循环流化床仿真的数学模型都采用反应动力学的方法。本文采用了CSTR的平衡反应算法,对循环流化床建立仿真的数学模型,已用于100MW循环流化床的实际工业装置仿真培训器中,算法比较稳定,模拟了循环流化床的开停车、事故处理和正常操作,动态趋势和实际工业装置相符。与设计值相比,模拟的稳态误差在1%以内,动态误差在5%以内。

关键词：仿真 CSTR模型循环流化床